News for hackers. Stuff that matters.
Re:Omicron variant more resistant to vaccine but causes less... by ufo on Tuesday December 14, 2021 @10:18AM (#29552456)
The title is misleading. It is possible that Omicron is just as severe and that the effect in the study is because a large percentage of the population had some immunity from a previous infection or vaccine.

> South Africa has a quite high seroprevalence of prior infection, particularly after delta, and in some parts of South Africa up to 80 percent of people were exposed to previous infection. We don’t think it’s a question of virulence, but more a question of exposure to vaccination and prior infection, so we would be cautious to try and interpret that this is a less virulent strain. We’ll have to see what happens in other parts of the world before we make a call on this.

Re:Omicron variant more resistant to vaccine but causes less... by gjsman-1000 on Tuesday December 14, 2021 @10:25AM (#29552541)
I would suspect that most people who are were already vulnerable have already passed or built immunity if the virus is equally dangerous, resulting in a lower than equal death rate despite equivalent risk.

Although... Can we never, not even once, be a little optimistic? To me, the news that we may be replacing COVID with a less severe strain is some of the best news of the year. COVID clearly isn't going away at this point, so by all means try to replace it with something weaker!

EDIT: Also, on a side note, the actual doctor who found Omicron said it was less dangerous. She even described it as "extremely mild." https://www.vice.com/en/article/xgddw4/omicron-variant-inter... Needless to say, politicians and news hosts decided to completely ignore her description about it.

Re:Omicron variant more resistant to vaccine but causes less... by wokwokwok on Tuesday December 14, 2021 @10:47AM (#29552855)
Wanting something to be true does not make it true.

Even if it turns up to actually be true, the fact that so many people want it to be true is an excellent reason to be cautious in how you look at things here, because that is causing a lot of people to say things that haven’t been proven to be true.

The evidence so far looks like cause to be cautiously optimistic, but when the people giving out that evidence say “it’s too soon to be sure”, then pay attention.

It’s too soon to be sure.

Re:Omicron variant more resistant to vaccine but causes less... by timr on Tuesday December 14, 2021 @11:46AM (#29553720)
> Wanting something to be true does not make it true.

Indeed. And wanting something to be false does not make it false. People on both sides of this debate are far too eager to run with their preferred opinion and accuse anyone who disagrees of "misinformation".

"I don't like this paper, and I see arguments against it, therefore it is dangerous and wrong."

It's petty behavior.

Re:Omicron variant more resistant to vaccine but causes less... by choeger on Tuesday December 14, 2021 @01:14PM (#29555085)
The thing is that even the pessimistic explanation of the data (high immunity due to prior infection) should give everyone (except maybe some countries) hope. After all, most industrialized countries should have a double digit percentage of prior infection by now.
Re:Omicron variant more resistant to vaccine but causes less... by galangalalgol on Tuesday December 14, 2021 @11:28AM (#29553418)
Don't all viruses become more mild over time? Even Ebola gets much less lethal towards the end of an outbreak as it evolves to preserve its habitat. Small pox is a possible counter ecample it seems like it was pretty lethal for millennia.
Re:Omicron variant more resistant to vaccine but causes less... by ceejayoz on Tuesday December 14, 2021 @11:33AM (#29553504)
> Even Ebola gets much less lethal towards the end of an outbreak as it evolves to preserve its habitat.

No, it doesn't.

https://www.politifact.com/factchecks/2021/dec/08/facebook-p...

> The claim makes a broad generalization about pathogens that’s not supported by science. It has been well-documented that pathogens can evolve to be more virulent. And many viruses, including HIV and Ebola, have in fact become more lethal over time.

As you note, smallpox disproves the idea that viruses automatically become mild. It had thousands of years to do so and carried a 30% mortality rate still.

Re:Omicron variant more resistant to vaccine but causes less... by iso1631 on Tuesday December 14, 2021 @11:39AM (#29553615)
No, they tend to become more spreadable, but there's no reason they couldn't become even more harmful as they evolve, rather than less. The strains that will win out are those that do less immediate harm (thus become more spreadable as people don't stay in bed ill), but that doesn't mean after a week or two they couldn't get really harmful (we saw in the first wave that covid was generally a week of nothing, a week of symptoms at home, a week in hospital, a week in intensive care, and then into the grave, with a certain chance of recovering each week. Imagine a mutation which reduced that recovering chance, that would cause more death, but not affect the spreading in the first week)
Re:Omicron variant more resistant to vaccine but causes less... by hnaccount_rng on Tuesday December 14, 2021 @11:44AM (#29553704)
Only if you restrict to viruses that haven't killed their host population ;) But even then you could just wait until another higher-intelligence species appears and give them the same pathogen.

If everything survives, the resulting community can live with each other and that requires a sufficiently mild virus. However that doesn't help predict the future, because you can't enforce the precondition of everyone surviving.

Re:Omicron variant more resistant to vaccine but causes less... by mmastrac on Tuesday December 14, 2021 @11:33AM (#29553490)
There's no guarantee a virus gets more lethal. Viruses select for survival and less lethality is _one_ strategy (though a fairly good one).
Re:Omicron variant more resistant to vaccine but causes less... by ethbr0 on Tuesday December 14, 2021 @11:47AM (#29553741)
In the context of a pandemic there's also the relative fitness (strain vs strain) optimization.

So a more lethal virus during a pandemic must also be more transmissible, as it's actively competing for the same susceptible hosts with other circulating strains. If another strain gets there first, chances are it's going to prime that host's immune system sufficiently to prevent reinfection.

Which means it needs not just more lethal mutations, but also more transmissible ones. The probability of all of those coinciding seems low, as the former are more likely to arise in immunocompromised hosts, and the latter in circulation among dense populations, no?

Re:Omicron variant more resistant to vaccine but causes less... by nicoburns on Tuesday December 14, 2021 @11:41AM (#29553644)
No. They often do, but not always. Other counter examples: Rabies. Spanish Flu.
Re:Omicron variant more resistant to vaccine but causes less... by soperj on Tuesday December 14, 2021 @12:14PM (#29554199)
How's that going with Aids?
Re:Omicron variant more resistant to vaccine but causes less... by NicoJuicy on Tuesday December 14, 2021 @11:23AM (#29553338)
According to what I heard through the Covid update of work. Omicron settles more in the nose and not as much in the long ( their source was a doctor).

Although it's too early to be sure, it would explain both an increased transmissibility and a milder variant.

Re:Omicron variant more resistant to vaccine but causes less... by megablast on Tuesday December 14, 2021 @12:36PM (#29554492)
You understand that what you said is pure nonsense right?
Re:Omicron variant more resistant to vaccine but causes less... by NicoJuicy on Tuesday December 14, 2021 @04:11PM (#29557829)
Based on? The second part seems logical tbh and the first part actually did happen ( 1200 employees and a decent company, so I doubt their would be lies. We're no better.com ).

Also, it is similar enough to what i heard before from a conference about covid previous year.

Re:Omicron variant more resistant to vaccine but causes less... by NicoJuicy on Tuesday December 14, 2021 @06:22PM (#29559547)
COVID update from work is actually a weekly online meeting that started because of COVID. I forgot by now that it would sound weird for an outsider. Everything is discussed what's happening in and out of the company ( supply chain shortage, COVID variants, cyber security,...) There's a q&a if someone has questions/concerns.

It's actually a worldwide and European meeting ( so 2 times/ week for me actually) and it's a pretty good alternative for keeping company culture and bringing it somewhat online.

Yes, it's not required if you don't want to attend :)

Re:Omicron variant more resistant to vaccine but causes less... by spurgu on Tuesday December 14, 2021 @11:54PM (#29562261)
Why is it nonsense? He meant "lung", not "long" btw.
Re:Omicron variant more resistant to vaccine but causes less... by NicoJuicy on Wednesday December 15, 2021 @03:32PM (#29571249)
Aaah. Okay, that could explain it :p

Thanks!

Re:Omicron variant more resistant to vaccine but causes less... by mitigating on Tuesday December 14, 2021 @11:46AM (#29553723)
"The omicron variant is cause for concern — but not panic" - Biden

"Most Omicron cases in US have been mild but most were vaccinated" from CDC reported on by CNN and MSNBC

https://www.cnn.com/2021/12/10/health/omicron-cases-us-cdc/i...

https://www.nbcnews.com/health/health-news/cdc-report-omicro...

There may be more but that was a quick Google search. You said "politicians and news hosts decided to completely ignore her description about it." but that's incorrect

Re:Omicron variant more resistant to vaccine but causes less... by altcognito on Tuesday December 14, 2021 @12:28PM (#29554375)
It shouldn’t be surprising that the people that complain most vociferously about “The media panic” are selectively hearing only what reinforces their view of the media.

That being said there are a lot of people hand wringing about “we don’t know yet, we don’t know yet” in this very thread. Three weeks into it, and the evidence is almost overwhelming: it is not likely to be nearly as bad.

I followed the original covid news in early January and I fought against the narrative that it was “just the flu”. We would know by now if the news was bad.

That being said, folks should continue to remain vigilant in those areas where spread is prevalent.

Re:Omicron variant more resistant to vaccine but causes less... by panarky on Tuesday December 14, 2021 @10:55AM (#29552937)
> a little optimistic?

Sure, for this immediate wave [more transmissible less virulent] is better than [more transmissible more virulent].

But that's awfully myopic. What happens after that?

Since mutation rate is a function of the number of viral particles, and more transmission means many more hosts incubating many more particles, we should expect to see more new variants, faster.

So the probability just went up that we'll get a new wave of a new variant that's [more transmissible more virulent] and will kill 10x more people than alpha through omicron will.

That's a probability and not a certainty, but life is probabilistic and our risk level just went up a lot.

Re:Omicron variant more resistant to vaccine but causes less... by marpstar on Tuesday December 14, 2021 @11:01AM (#29553024)
It's a miracle that the human race has survived this long, and COVID is clearly not driving us to extinction.
Re:Omicron variant more resistant to vaccine but causes less... by adventured on Tuesday December 14, 2021 @11:28AM (#29553420)
> It's a miracle that the human race has survived this long

It's not a miracle or anything close to that level of implied bafflement (devoid of being able to explain it rationally). We're excellent survivors overall, and a lot more than that. We're very skilled at resource utilization, we're relatively talented at conceptual thinking, we're competent tool builders on a planet ripe for it, we possess the ability to plan far ahead and understand consequences numerous steps out, we have memory capabilities that are quite effective across most of our lifetimes, most of our species is not particularly violent and is generally good natured & friendly (only a very small fraction of the population will ever commit serious acts of violence), we function quite well together in groups/tribes/cities/nations (compounded, shared outcomes), and so on. It's not particularly complicated, despite the doomsayers that will never stop existing amongst us (their mentality says more about them than it does the human race).

Re:Omicron variant more resistant to vaccine but causes less... by dham on Tuesday December 14, 2021 @11:41AM (#29553639)
If the world wasn't so fat and it was 50 years ago, COVID probably would have been nothing, or the Hong Kong Flu.
Re:Omicron variant more resistant to vaccine but causes less... by Sargos on Tuesday December 14, 2021 @11:44AM (#29553702)
The Spanish Flu was over a hundred years ago and hit the world the same way Covid did even though there was no McDonald's or obesity epidemic back then.
Re:Omicron variant more resistant to vaccine but causes less... by dham on Tuesday December 14, 2021 @11:47AM (#29553759)
Yes but Spanish Flu was really really bad. Affected everyone. Covid is not the Spanish Flu or even the Flu. The flu kills children and is indiscriminate. 80% of hospitalizations and deaths from Covid are related to weight.

We should have prioritized health and Vitamin D in April 2020. At that time it was clear it was mainly affecting overweight people. Of course even almost 2 years later people still don't think that as a whole. They say comorbidities. Just say it like it is... it's mostly fat people. The news and society won't say that.

Re:Omicron variant more resistant to vaccine but causes less... by peter422 on Tuesday December 14, 2021 @12:02PM (#29554032)
And long covid? The two people I know who had longer term side effects were quite healthy.

Also by some definitions America is “mostly fat people” so your point is not that meaningful to begin with.

Re:Omicron variant more resistant to vaccine but causes less... by dham on Tuesday December 14, 2021 @12:25PM (#29554342)
You mean post-viral syndrome? I mean yea it's a thing with viruses but it will go away eventually. I had a cold a few years ago and was sick for like 3 months. Some of long covid is mental, so there's that aspect. Some say vaccination can help but that might just play into the mental aspect.

The human mind can create symptoms very easily, especially if every day you get bombarded by social media and news about Covid.

> Also by some definitions America is “mostly fat people” so your point is not that meaningful to begin with

True, but I'm just saying this wouldn't have been an issue 30 - 50 years ago.

Re:Omicron variant more resistant to vaccine but causes less... by kenjackson on Tuesday December 14, 2021 @12:34PM (#29554463)
> 80% of hospitalizations and deaths from Covid are related to weight.

Citation for this? I've never heard this at all.

Re:Omicron variant more resistant to vaccine but causes less... by dham on Tuesday December 14, 2021 @12:53PM (#29554751)
Re:Omicron variant more resistant to vaccine but causes less... by kenjackson on Tuesday December 14, 2021 @01:03PM (#29554915)
OK, that says something slightly different. Because 42% of the US population is obese, even if Covid hospitalized completely at random you'd expect 42% of those admitted to be obese (not that obesity is the cause of 42% of admissions). They saw 50% admitted were obese. This implies that being obese increases the risk of hospitalization by ~20%.

But still useful data. Thanks.

Re:Omicron variant more resistant to vaccine but causes less... by dham on Tuesday December 14, 2021 @06:04PM (#29559373)
I mean I think it says something very blunt. If you're not overweight you probably don't need 5 boosters and you can probably go about your day and play the odds. People still know how to play the odds right, they do it everyday? It's funny to me people are so scared of Covid when they're going to die of Heart Disease or Cancer.

There's just no nuance in any conversation related to Covid.

Re:Omicron variant more resistant to vaccine but causes less... by kenjackson on Wednesday December 15, 2021 @09:54AM (#29566720)
I honestly don’t think you understand the data even after I explained it to you. Unfortunately this is why even basic headlines get misunderstood by the public.

Let me ask you a question. If weight had absolutely no impact on Covid then what expected percentage of Covid hospitalizations would be with overweight people?

Re:Omicron variant more resistant to vaccine but causes less... by wbsss4412 on Tuesday December 14, 2021 @12:34PM (#29554452)
80% of hospitalizations and death globally or in the US specifically?

Globally that is one thing, but if that data point is in the US, then the baseline population is something like 60-70% overweight/obese to begin with. In which case, that elevation from baseline isn’t as significant as implied.

Re:Omicron variant more resistant to vaccine but causes less... by ethbr0 on Tuesday December 14, 2021 @11:50AM (#29553813)
There was a world war distracting resources.
Re:Omicron variant more resistant to vaccine but causes less... by jessaustin on Tuesday December 14, 2021 @01:05PM (#29554947)
WWI actually caused the epidemic. The first cases appeared in Kansas, and many doughboys were infected at Fort Riley before carrying the illness to Europe. Woodrow Wilson, who lied about staying out of the war until the day after his reelection, may have been the USA president who harmed the world the most.
Re:Omicron variant more resistant to vaccine but causes less... by native_samples on Tuesday December 14, 2021 @01:42PM (#29555487)
Spanish Flu definitely not the same severity as COVID, not even close.

Apparently though people's risk perceptions about COVID are wildly off base, by orders of magnitude.

https://news.gallup.com/opinion/gallup/354938/adults-estimat...

40% of US Democrats think COVID hospitalization risk if you're unvaccinated is 50%! Fifty percent! The real answer is less than 1%. Other polls have shown similar things for fatality rates, like estimated 16% IFR on average in France. It really makes me realize why people act in such extreme ways, if that's what they think.

COVID is to a large extent a total failure of our societies ability to disseminate accurate information. Unfortunately this misinformation catastrophe is largely the work of the very same people who are constantly complaining about misinformation.

Re:Omicron variant more resistant to vaccine but causes less... by kenjackson on Tuesday December 14, 2021 @05:10PM (#29558733)
How is it possible that anyone thinks 50% of all unvaccinated people have been hospitalized -- for just about anything! Seeing polls like this give me so little faith in our ability to make judgments as a country on anything non-trivial.
Re:Omicron variant more resistant to vaccine but causes less... by panarky on Tuesday December 14, 2021 @11:08AM (#29553127)
Is it optimism to settle for any outcome that's better than extinction?
Re:Omicron variant more resistant to vaccine but causes less... by jodrellblank on Tuesday December 14, 2021 @11:19AM (#29553286)
Are you arguing the equivalent of "something increasing the chance of another world war is not a concern, because previous world wars clearly didn't drive humans to extinction"?
Re:Omicron variant more resistant to vaccine but causes less... by mikenew on Tuesday December 14, 2021 @12:49PM (#29554682)
Covid can't just mutate to become more and more transmissible off to infinity. The likelihood of a new variant being able to out compete Omicron is lower than a variant that can out compete Delta. There's also selection pressure towards milder disease, because someone with milder disease is more likely to be out in the world spreading it than they are to be quarantined at home.

The probability of a more transmissible, more virulent strain just went down, not up. It certainly isn't zero, but "more transmissible less virulent" is exactly how viruses tend to evolve. Mutations are a dice roll and it there's no way to be sure of anything, but being a little optimistic is completely appropriate.

Re:Omicron variant more resistant to vaccine but causes less... by panarky on Tuesday December 14, 2021 @08:13PM (#29560686)
> selection pressure

How does selection pressure work when the disease is spread by people with no symptoms?

Re:Omicron variant more resistant to vaccine but causes less... by rajin444 on Tuesday December 14, 2021 @11:06AM (#29553099)
How do you reconcile this with the human race existing for so long? I guess you could make the argument global travel has changed things, but I’m not sure.
Re:Omicron variant more resistant to vaccine but causes less... by lisper on Tuesday December 14, 2021 @11:28AM (#29553426)
> How do you reconcile this with the human race existing for so long?

For a disease to make us go extinct it would have to be highly transmissible and have a fatality rate of close to 100%. Anything less than that, and evolution will produce a generation of humans that are resistant to (or otherwise able to protect themselves from) the disease, and from there the population will replenish itself. The great plague had a fatality rate of 30% and it didn't even come close to threatening our existence as a specie. (In fact, the resulting redistribution of wealth arguably contributed to the advent of the renaissance.)

Re:Omicron variant more resistant to vaccine but causes less... by ceejayoz on Tuesday December 14, 2021 @11:17AM (#29553261)
I mean, we can strive for more than just existence. The Black Death didn't wipe us out, but that doesn't mean it was fun to undergo.
Re:Omicron variant more resistant to vaccine but causes less... by newbamboo on Tuesday December 14, 2021 @11:13AM (#29553212)
This. When omicron and delta mate and produce offspring, we’re going to be screwed. Deltas virulence + omicron transceptability = the Great Wave of summer 2022. It will be a good year for Pfizer investors and Russia.
Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @12:30PM (#29554411)
When omicron and delta mate and produce offspring

While there can be recombinations of some similar viruses, that's not the common way that viruses propagate, and it's not mating. Point mutations are much more common. And if they do recombine there's no reason to (automatically) expect that the results will be the worst characteristics of both.

Re:Omicron variant more resistant to vaccine but causes less... by brokensegue on Tuesday December 14, 2021 @11:22AM (#29553330)
The south African doctor had insufficient evidence to conclude it was "extremely mild". Waiting for more data was the right course.
Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @11:43AM (#29553674)
Optimism on the part of news outlets can be dangerous here. It may cause people to prematurely relax their precautions, and if it turns out to be wrong it will further erode trust in media outlets that jumped the gun. Considering the study was comparing Omicron to the initial wave of 2020 infections (a strange choice) I am not confident in the results. If it turns out to be correct, it will be more of an accident than accurate analysis.

As for the doctor that discovered it: Here experience with infected individuals is anecdotal data. She has not, to my knowledge, been involved in systematic studies. She is a general practitioner so here experience with this has been on the ground, primarily with the patients she has seen. Certainly this is useful but it is not a replacement for well-formed studies. Medical research and epidemiology are distinctly different activities from medical practice, even if many people involved in both have a medical degree.

Re:Omicron variant more resistant to vaccine but causes less... by tn890 on Tuesday December 14, 2021 @11:05AM (#29553086)
> I would suspect that most people who are were already vulnerable have already passed or built immunity if the virus is equally dangerous, resulting in a lower than equal death rate despite equivalent risk.

You are forgetting about the most vulnerable group of all: immunosuppressed people.

They cannot mount a sufficient immune response, in severe immunosuppression like after a transplant event months or years after. In some cases the covid mortality for these people can approach 40% for young adults.

We have to be mindful of people like this when thinking about dropping mask mandates and such. Or "whoever's not vaccinated dies of their own fault". Not 100% true.

We as a society must protect those most vulnerable.

Re:Omicron variant more resistant to vaccine but causes less... by wonderwonder on Tuesday December 14, 2021 @11:18AM (#29553268)
I live in a state where mask mandates are essentially gone. Very few people wear masks here and they are not required in schools so only ~5% of kids are wearing them at my children's elementary school. Everything seems pretty good so far, no marked rise in cases and almost no cases in my kids school over the last year, maybe 25 total, all mild. I am in no way saying masks don't work, in fact I think that they do. With that said, I have not worn a mask in a long time, I am fully vaccinated including a booster and essentially figure that is enough. I work from home so if I get covid its going to be from my kids.

"We have to be mindful of people like this when thinking about dropping mask mandates and such."

Not arguing with you, just genuinely interested on how long you would advocate for mask mandates? Would you be willing to accept mask mandates in perpetuity?

Re:Omicron variant more resistant to vaccine but causes less... by nicoburns on Tuesday December 14, 2021 @11:48AM (#29553765)
> Would you be willing to accept mask mandates in perpetuity?

I think it depends on location. In key environments like public transport and supermarkets and other spaces that everyone needs to be able to access it seems reasonable to me that we might keep them for at least a 5-10 year horizon if that proves necessary. It just doesn't seem like a big deal to wear a mask, and it would cut down on the need for more restrictive measures like lockdowns.

Re:Omicron variant more resistant to vaccine but causes less... by lieut_data on Tuesday December 14, 2021 @12:22PM (#29554298)
> It just doesn't seem like a big deal to wear a mask, and it would cut down on the need for more restrictive measures like lockdowns.

My wife has a medical exemption from wearing a mask. She cannot live a normal life when the standard response to her being out in public is disgust, constant questioning, or outright rejecting her due to "in-store policies."

My father has been wearing a mask, but constantly deals with hyperventilation issues. He's working with his family doctor to determine next steps.

Some things are a big deal for some people. I support anyone wearing a mask if they so choose. I oppose mask mandates as a one-size fits all solution.

Re:Omicron variant more resistant to vaccine but causes less... by kenjackson on Tuesday December 14, 2021 @12:37PM (#29554500)
Actually legit medical exemptions are rare. Why can't we do mandates with exemptions (maybe an exemption card from a doctor)?
Re:Omicron variant more resistant to vaccine but causes less... by lieut_data on Tuesday December 14, 2021 @01:16PM (#29555115)
> Why can't we do mandates with exemptions (maybe an exemption card from a doctor)?

I expect my wife would have to strap her card over her mouth to satisfy the social pressure to conform. It's not in most people's imaginations that anyone else could suffer from something that doesn't bother them.

Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @01:23PM (#29555211)
> It just doesn't seem like a big deal to wear a mask

What about the fully vaccinated, boostered employees who work at these places? Should they also continue wearing masks despite being at virtually zero risk of major covid issues?

But yeah, no thanks. We didn't do masks in 2019 and we sure as heck shouldn't keep doing them going forward. Masks were a hack to get us to vaccines. They aren't something we should be keeping around anymore.

Re:Omicron variant more resistant to vaccine but causes less... by rajup on Tuesday December 14, 2021 @12:07PM (#29554100)
No thanks.
Re:Omicron variant more resistant to vaccine but causes less... by iso1631 on Tuesday December 14, 2021 @11:50AM (#29553817)
It's interesting how Scotland, which kept a mask mandate, and England, which dropped it, affected cases.

From start to end of October, cases per 100k, 7 day average

Glasgow -- 300->220

Edinburgh -- 210->250

Manchester -- 290->220

Birmingham -- 250->280

4 similar cities, two with mask mandates, two without.

And smaller ones

Aberdeen -- 267->330

Southampton -- 300->410

Perth -- 320->260

Hereford -- 290->580

So there may be something there, would need more data to really see, but it certainly isn't a glowing mandate for masks

Re:Omicron variant more resistant to vaccine but causes less... by roywiggins on Tuesday December 14, 2021 @12:41PM (#29554564)
There's already data that shows masks work.

https://med.stanford.edu/news/all-news/2021/09/surgical-mask...

Re:Omicron variant more resistant to vaccine but causes less... by iso1631 on Tuesday December 14, 2021 @03:20PM (#29556990)
Perhaps, but given there's doesn't seem to be a clear difference between Scotland and England, that leads to questions like

1) Were people in Scotland (with higher masking) being less cautious in other areas (washing hands, staying further away, etc)

2) Was the weather worse in Scotland, leading to more closed windows

3) Are people in Scotland more likely to be tested and thus more cases caught

The problem I have is that

The Scientific method comes out with great studies (wearing masks, all things being equal, reduces transmission)

That leads to a prediction (enforcing masks reduces cases figures)

That prediction doesn't hold out (Scottish cases figures)

So we need to revisit the prediction,

1) Does a mask mandate increase mask usage (anecdotally it appears so, but I only went to Glasgow and Manchester in October)

2) Does increased mask usage lead to other behaviours which would increase risk

3) Does increased mask usage lead to more awareness in testing

4) Do anti mask people go round licking door handles to try to spread covid to prove their points

These are perfectly valid questions, yet you can't ask them, because half the responses will be some idiotic cultish anti-mask covid denier, and the others will be some cultish mask worshiper

Re:Omicron variant more resistant to vaccine but causes less... by defaultprimate on Tuesday December 14, 2021 @01:33PM (#29555344)
https://boriquagato.substack.com/p/bangladesh-mask-study-do-...

https://wwwnc.cdc.gov/eid/article/26/5/19-0994_article

"At present there is only limited and inconsistent scientific evidence to support the effectiveness of masking of healthy people in the community to prevent infection with respiratory viruses, including SARS-CoV-2 (75). A large randomized community-based trial in which 4862 healthy participants were divided into a group wearing medical/surgical masks and a control group found no difference in infection with SARS-CoV-2 (76). A recent systematic review found nine trials (of which eight were cluster-randomized controlled trials in which clusters of people, versus individuals, were randomized) comparing medical/surgical masks versus no masks to prevent the spread of viral respiratory illness. Two trials were with healthcare workers and seven in the community. The review concluded that wearing a mask may make little or no difference to the prevention of influenza-like illness (ILI) (RR 0.99, 95%CI 0.82 to 1.18) or laboratory confirmed illness (LCI) (RR 0.91, 95%CI 0.66-1.26) (44); the certainty of the evidence was low for ILI, moderate for LCI."

https://apps.who.int/iris/bitstream/handle/10665/337199/WHO-...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546829/

Re:Omicron variant more resistant to vaccine but causes less... by roywiggins on Tuesday December 14, 2021 @01:38PM (#29555414)
Look, I'm not qualified to evaluate a study like this, but between Science and "el gato malo" published on Substack, I think I'm going to have to go with Science on this one, pending some recognized expert in the field with a human name saying otherwise.
Re:Omicron variant more resistant to vaccine but causes less... by mikeyouse on Tuesday December 14, 2021 @01:53PM (#29555690)
The author of the study that the bad cat is trying to discredit wrote a long, persuasive rebuttal to the simplistic critiques he's been reading on Tyler Cowen's blog;

https://marginalrevolution.com/marginalrevolution/2021/11/ja...

They saw a significant reduction in covid presence in communities with more masking -- even though total masking was still only 40% in those communities -- which is very much in line with all the other literature.

I literally can't believe people still pretend like masks (especially surgical/KN95s) don't protect people when it's completely self-evident since we've used them forever to protect people in medical settings.

Re:Omicron variant more resistant to vaccine but causes less... by defaultprimate on Tuesday December 14, 2021 @01:58PM (#29555770)
It doesn't address the primary criticisms of the bad cat, and you should really read the comments on the article you linked, as well as they meta-analyses I provided on mask effectiveness when it comes to respiratory illnesses in healthcare and community settings.

They don't work, at all, across decades of research and dozens of studies. They're not going to magically start working for COVID when they haven't worked for the flu or any other respiratory virus in the past.

>forever to protect people in medical settings.

Surgical masks in medical settings are designed to protect from bacterial infections, not viral ones.

Re:Omicron variant more resistant to vaccine but causes less... by mikeyouse on Tuesday December 14, 2021 @02:08PM (#29555915)
> and you should really read the comments on the article you linked, as well as they meta-analyses I provided on mask effectiveness when it comes to respiratory illnesses in healthcare and community settings.

Unfortunately, Tyler Cowen's blog has worse Covid commentary than even HN does, which is pretty impressive given the amount of HCQ/Ivermectin/bioweapon conspiracy theorizing here.

> Surgical masks in medical settings are designed to protect from bacterial infections, not viral ones.

This is patently untrue.. you're not one of those "virus particles can fit through masks" people are you? As just one example of how obvious it is that masks protect against viruses in HCW from the last SARS outbreak;

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112437/

Re:Omicron variant more resistant to vaccine but causes less... by defaultprimate on Tuesday December 14, 2021 @02:15PM (#29556011)
I literally linked several meta-analyses that show it's patently true.
Re:Omicron variant more resistant to vaccine but causes less... by mikeyouse on Tuesday December 14, 2021 @02:35PM (#29556300)
You should perhaps read the studies you've linked a bit closer? When mentioned (as several of them are explicitly about masks in non-healthcare settings) - they all advocate for universal masking in healthcare settings specifically to limit the spread of Covid...

> Although more research on universal masking in heath settings is needed, it is the expert opinion of the majority (79%) of WHO COVID-19 IPC GDG members that universal masking is advisable in geographic settings where there is known or suspected community or cluster transmission of the SARS-CoV-2 virus.

> 1. In areas of known or suspected community or cluster SARS-CoV-2 transmission, universal masking should be advised in all health facilities (see Table 1).

> All health workers, including community health workers and caregivers, should wear a medical mask at all times, for any activity (care of COVID-19 or nonCOVID-19 patients) and in any common area (e.g., cafeteria, staff rooms).

> Other staff, visitors, outpatients and service providers should also wear a mask (medical or non-medical) at all times

Re:Omicron variant more resistant to vaccine but causes less... by defaultprimate on Tuesday December 14, 2021 @02:38PM (#29556368)
Opinions not supported by empirical evidence are not opinions worth listening to.

"Experts" supported eugenics, antibacterial soap, breakfast cereal, the food pyramid, lobotomies, and all kinds of other things on the basis of popular "consensus"

Re:Omicron variant more resistant to vaccine but causes less... by mikeyouse on Tuesday December 14, 2021 @02:54PM (#29556629)
See now you've gone and boxed yourself into the typical HN corner...

The people making those recommendations are experts in the field and have all read the relevant research. Weighting the good studies vs. the bad ones, measuring evidence, etc. They literally exist to give guidance on world health matters based on the spectrum of results from all these different researchers.

And here you are, telling me that in your opinion, we should ignore their assessment and only trust these few specific papers that you choose to emphasize. (At least you've stopped advocating for ivermectin now?)

A bit of a paradox to get people to rely on your opinion when you've previously said we shouldn't rely on opinions isn't it? Or is it just that you don't like the WHO's opinion on World Health issues because they might be in the pocket of "big surgical mask".

Re:Omicron variant more resistant to vaccine but causes less... by defaultprimate on Tuesday December 14, 2021 @03:13PM (#29556887)
I haven't boxed myself in anywhere, I've maintained the same position throughout.

I'm not telling you anything in my opinion. I'm telling you what the empirical evidence says or doesn't say.

I have not stopped advocating Ivermectin. The empirical evidence shows that it is still an extremely cheap, safe, and correlated treatment demonstrated across populations of billions through a mechanism of action that has been well established.

There's literally no reason not to try it, and there's a reason it's part of treatment regimens across several countries. Its use doesn't involve eroding the liberty of the populace or solidifying absolute power of state. It has virtually zero side effects medically or socioculturally, unlike things like masks or vaccines that have zero long term data

Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @02:18PM (#29556050)
you should really read the comments on the article you linked

Even if I disagree with TC on something, I still think he's pretty much intellectually honest, i.e., is not beholden to one political agenda or another simply because it matches his world view or completely unaware of competing data. And he often does a good job in striking a balance on ideology & practicality (State Capacity Libertarianism comes to mind)

However the comments section on MR are often a hot mess of cherry picking or misinformation parroted back by people trying emulate TC's style without anything approaching his intellectual rigor.

Re:Omicron variant more resistant to vaccine but causes less... by defaultprimate on Tuesday December 14, 2021 @01:44PM (#29555530)
Skepticism and methodological criticism are definitionally "science". Not cult like faith. Ad hominems and appeals to authority are not valid arguments.
Re:Omicron variant more resistant to vaccine but causes less... by roywiggins on Tuesday December 14, 2021 @02:02PM (#29555839)
Paying more attention to information in a peer-reviewed journal than information in a pseudonymous substack is not "cult-like faith." Of course the study could be wrong.
Re:Omicron variant more resistant to vaccine but causes less... by defaultprimate on Tuesday December 14, 2021 @02:05PM (#29555872)
The study is not and has not passed peer review.
Re:Omicron variant more resistant to vaccine but causes less... by roywiggins on Tuesday December 14, 2021 @02:08PM (#29555924)
Hasn't it? Looks published to me. It has a doi and everything.

https://www.science.org/doi/10.1126/science.abi9069

Re:Omicron variant more resistant to vaccine but causes less... by defaultprimate on Tuesday December 14, 2021 @02:12PM (#29555973)
My mistake, the link in the article you first posted still shows it as a working paper and I couldn't find it with the original title when searching.

Interestingly the DOI does not show up

https://dx.doi.org/

Here's some further criticisms:

https://www.researchsquare.com/article/rs-1073440/latest.pdf

https://arxiv.org/abs/2112.01296

https://bmcpublichealth.biomedcentral.com/articles/10.1186/s...

Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @11:57AM (#29553938)
There are plenty of scientific studies showing that masks work.
Re:Omicron variant more resistant to vaccine but causes less... by kansface on Tuesday December 14, 2021 @03:47PM (#29557423)
Obviously, the material a mask is made from stops medium sized particles from flowing through some highish percentage of the time. No good faith actor is disputing that. Studies don't control for real world usage, actual public adoption, actual masks, etc. They also do not control for changes in behavior that we'd expect to occur contemporaneously to the time periods mask mandates are adopted (ie, during spikes in infection). When infections go up, I personally stop going places where lots of people congregate - a huge percentage of people change their behavior in ways that are both germane and impossible to track in response to perceived risk. They also do not or can not control for the differences in behavior in the societies that can actually adopt and enforce mask mandates in the first place; ie, a city that refuses a mandate in the face of a spike has citizens that are more risk tolerate (or something) as compared to eg SF.
Re:Omicron variant more resistant to vaccine but causes less... by adolph on Tuesday December 14, 2021 @12:44PM (#29554609)
I think the number analyzing actual mask usage is fewer than you’d think.
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @01:25PM (#29555238)
All conducted in the heat of the moment where saying anything that gives the slightest wiff of "masks don't work" gets you shunned, your career destroyed, and all social media platforms labeling your content as "misinformation".

Yeah... I'm sure all these studies done post-2019 are totally legit though.

Re:Omicron variant more resistant to vaccine but causes less... by iso1631 on Tuesday December 14, 2021 @12:40PM (#29554550)
But do they show how much mask mandates work in the real world, do they explain why Edinburgh and Glasgow are indistingishable from Mancehster and Birmingham in numbers of cases detected?
Re:Omicron variant more resistant to vaccine but causes less... by Aloha on Tuesday December 14, 2021 @12:51PM (#29554719)
I think in reality, COVID fatigue has set in, and thats the issue.
Re:Omicron variant more resistant to vaccine but causes less... by iso1631 on Wednesday December 15, 2021 @06:37AM (#29564586)
Via what mechanism? Were people not wearing masks in Scotland despite the mandate? Were they wearing masks in England despite no mandate? Is there enough difference in behaviour between Glasgow and Manchester to explain the difference?
Re:Omicron variant more resistant to vaccine but causes less... by roywiggins on Tuesday December 14, 2021 @11:33AM (#29553499)
We are maybe a couple months from Pfizer's new antiviral becoming widely available, and it will probably work for immune compromised people. There's also a recent EUA for a long-acting antibody PrEP injection that should help immune compromised people avoid infection in the first place.

Both of these may be widely available in the US quite soon.

Re:Omicron variant more resistant to vaccine but causes less... by wonderwonder on Tuesday December 14, 2021 @11:50AM (#29553819)
This is a good response and I think would be something that should be taken into account. I am still not going to start masking again unless a much more severe variant rises but I can understand setting a firm deadline based on an emerging technologies. Issue is that there will never be a 100% solution and some states more willing than others to let mandates run forever. What happens if those emerging technologies are not as effective as hoped? It becomes a slippery slope with the deadline kicked down the road. Personally I think we are all going to get covid eventually in much the same way we all get the flu. Everyone that wanted to get vaccinated (in the US) and boosted has had a chance to do so now. Most Americans that want to avoid human contact can for the most part via amazon and food delivery services, work is obviously a different matter for most people. Perhaps I am selfish which I am open to, but at this point after having taken 3 shots and been very mask conscious for the first ~14 months I am tapped out and willing to roll the dice as the risk ratio seems relatively low to my age group and I have no pre-existing morbidities.
Re:Omicron variant more resistant to vaccine but causes less... by roywiggins on Tuesday December 14, 2021 @12:39PM (#29554532)
The Pfizer data on their new pill Paxlovid is very good. It's not emerging, it's here and will be available to people very soon. We will probably all get covid, wouldn't it be better if we all got it after treatments that cut deaths by 90% are widely available?

https://www.washingtonpost.com/health/2021/12/14/does-pfizer...

Re:Omicron variant more resistant to vaccine but causes less... by landemva on Tuesday December 14, 2021 @01:00PM (#29554868)
The unmentionable and ridiculously safe antiviral is available today. But Ivermectin is cheap so it must not be considered.
Re:Omicron variant more resistant to vaccine but causes less... by mikeyouse on Tuesday December 14, 2021 @01:57PM (#29555756)
If only it worked at all, that'd be a great option.
Re:Omicron variant more resistant to vaccine but causes less... by landemva on Tuesday December 14, 2021 @02:56PM (#29556656)
NIH report says it does.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539925/ 'Ivermectin is an FDA-approved broad-spectrum antiparasitic agent with demonstrated antiviral activity against a number of DNA and RNA viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).'

Re:Omicron variant more resistant to vaccine but causes less... by mikeyouse on Tuesday December 14, 2021 @03:08PM (#29556805)
That's not an NIH report -- that's a random paper posted on the NIH domain. IVM may have some benefit in countries with parasite problems, unfortunately it doesn't do much in the rest of the world. Has already been discussed to death, there's no conspiracy, everyone would have loved for it to help but it really just doesn't;

https://astralcodexten.substack.com/p/ivermectin-much-more-t...

Re:Omicron variant more resistant to vaccine but causes less... by roywiggins on Tuesday December 14, 2021 @03:25PM (#29557073)
Yeah, it's so silly. It's not like there aren't studies and doctors willing to investigate cheap, effective treatments for covid with existing drugs.

We know that steroids work because they were studied, they definitely work, they're cheap and now they're the standard of care. Why didn't the anti-ivermectin conspiracy come for dexamethasone? It's left unexplained...

Re:Omicron variant more resistant to vaccine but causes less... by Karsteski on Tuesday December 14, 2021 @11:26AM (#29553392)
> Not arguing with you, just genuinely interested on how long you would advocate for mask mandates? Would you be willing to accept mask mandates in perpetuity?

This is the problem, isn't it? For how long will these mandates be in place for? Right now, it's clear that they won't end until populations start revolting.

Re:Omicron variant more resistant to vaccine but causes less... by jkubicek on Tuesday December 14, 2021 @12:21PM (#29554280)
> Right now, it's clear that they won't end until populations start revolting.

That's not at all clear. My very cautious Northern California county dropped the mask mandates when cases started dropping this summer and only re-implimented them when cases and hospitalizations started to rise again.

I don't see any reason for them not to drop the mandates again when infection/hospitalization rates drop down to acceptable levels.

Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @01:26PM (#29555255)
> acceptable levels

Define acceptable levels? And does this suggest we continue masking every winter when "cases surge"? There will always be a variant of covid. Always. It's never going away. Basing mask mandates of any metric, be it cases, hospitalizations or deaths means every winter you'll be wearing a state mandated mask.

Re:Omicron variant more resistant to vaccine but causes less... by jkubicek on Tuesday December 14, 2021 @03:14PM (#29556899)
Are you trolling or do you really think that "every winter you'll be wearing a state mandated mask"?

We've been in this pandemic now for close to 2 years. At every single point, government rules and guidance have lagged recommendations from the experts. I'm confident that there is exactly 0 chance that any governmental body in the US is going to continue to mandate masking after it's no longer necessary.

Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @03:25PM (#29557079)
> Are you trolling or do you really think that "every winter you'll be wearing a state mandated mask"?

At this point, in the states that have mandates? I'm honestly not sure. There sure seems to be no rush to remove them despite having low "cases" and hospitalizations not being an issue. And given none of these states have given a single hint as to when they will go away... who knows?

States that continue this are absolutely normalizing mandated masks. Vaccines were sold as the end of masks (and they morally should have been regardless of what politicians say). Vaccines are the best we can do. Mandated masks in a post-vaccine world makes absolutely no sense at all. What other target could a government reasonably set after a vaccine? "Cases"? "Hospitalizations"? Well... those will always be there. So do we just keep doing this forever?

And if you say "hospital capacity" shouldn't these governments have fixed that already? We gave them two years and it was an emergency so where is the hospital capacity we put our lives on hold for? I mean, its still an emergency right? Shouldn't people be super pissed that government hasn't dealt with the actual problem they keep saying we have?

Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @12:38PM (#29554516)
"Everything seems pretty good so far"

There shortages of hospital beds across many states [0] If you want a full perspective on things, look further than your own state.

Unless you live in Wyoming, Colorado, Alaska, North Dakota, or Montana then everything is not going very well. Most people don't live in these states, and many of the states with loose mask mandates are not in that short list. A small are just about holding their ground, but about 40 states have seen a >= 15% increase in infections just in the last two weeks, and one of the least restrictive states for mask mandates (Texas) has increased by 80%. [1]

[0] https://protect-public.hhs.gov/pages/hospital-utilization

[1] https://www.nytimes.com/interactive/2021/us/covid-cases.html

Re:Omicron variant more resistant to vaccine but causes less... by landemva on Tuesday December 14, 2021 @12:56PM (#29554797)
Increase in infections does not equal death. It does bring the population closer to herd immunity. Infections and recovery bring sterilizing immunity, which is not provided by the shots.
Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @01:46PM (#29555564)
Infections have been a lagging indicator for deaths this entire time and immunity from infections does not appear to last as long as immunity from vaccinations. The people most resistant to right now are those who had covid already and get vaccinated.

I also don't understand your assessment that we are reaching (or can reach) herd immunity: We're not there on the common cold or influenza, and it seems COVID mutates at rates that will keep it around as well. Early evidence on Omicron indicates that it in particular is better at reinfection than other strains, so I hope the data in the next few weeks confirms its milder nature, but reinfection provides even more opportunity for variants to emerge.

We're much better off than we were a year ago: The holiday spike is (so far) not as bad, deaths are lower than last year at this time, and vaccines are widely available. But we're not back to normal yet (probably never will be) and I don't think we're doing as well right now as we could be, and I think we can make a lot more progress before we declare this thing over and adjust to a new status-quo.

Re:Omicron variant more resistant to vaccine but causes less... by TurkishPoptart on Tuesday December 14, 2021 @12:58PM (#29554835)
"cases" is not really a relevant variable anymore. It's been two years of a "pandemic" and I don't know a single person who's died from this ting yet. Of course, none of my Seattle neighbors will go out to walk their dog without wearing 3 masks.
Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @01:10PM (#29555032)
Cases are absolutely relevant: they have been a lagging indicator for deaths the entire time. It will take another 2-3 weeks to see how the current spike in cases plays out in deaths. Hopefully Omicron actually is less lethal, but we'll see soon enough.

As for your experience, it is not predictive or representative given the ~800,000 US deaths. Especially because you live in an admittedly very cautious area.

Re:Omicron variant more resistant to vaccine but causes less... by mikeyouse on Tuesday December 14, 2021 @01:59PM (#29555796)
It's funny too - there's apparently no consideration given to "maybe I don't know anyone who's died because everyone in my community is so cautious".
Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @02:02PM (#29555838)
Yes-- and yet just about anyone in this community would roll over laughing before pointing out the obvious if someone said "Why are we devoting so much energy to computer security? We've never even been hacked"
Re:Omicron variant more resistant to vaccine but causes less... by TurkishPoptart on Tuesday December 14, 2021 @02:05PM (#29555877)
That's a good point.
Re:Omicron variant more resistant to vaccine but causes less... by mikeyouse on Tuesday December 14, 2021 @02:12PM (#29555968)
Just as an anecdote -- I moved from a very cautious place (SF) to a place on the complete opposite side of the spectrum. I knew a handful of people who were infected in SF but none who died, but I know a ton of people here who have got the disease, including a bunch who have died. The local Facebook group is filled with prayer requests for loved ones who are being admitted under very dire circumstances and my healthcare worker friends here are completely shellshocked from all the death they've seen in the community.

Give me "unnecessarily wear a mask while walking the dog" and no deaths every day if my other option is "never wear a mask anywhere" and be surrounded by death.

Re:Omicron variant more resistant to vaccine but causes less... by sjwalter on Tuesday December 14, 2021 @11:22AM (#29553334)
> I am in no way saying masks don't work, in fact I think that they do.

This is still so hilarious to me. It's pretty obvious that some masks work, that is, n95 or whatever actual respirator masks. It's pretty obvious that other masks don't work at all, that is, 99.99% of masks worn by the public at large.

Re:Omicron variant more resistant to vaccine but causes less... by roywiggins on Tuesday December 14, 2021 @11:34AM (#29553518)
Surgical masks probably help on a population level.

https://med.stanford.edu/news/all-news/2021/09/surgical-mask...

Re:Omicron variant more resistant to vaccine but causes less... by jjgreen on Tuesday December 14, 2021 @12:44PM (#29554617)
This is still in peer-review
Re:Omicron variant more resistant to vaccine but causes less... by roywiggins on Tuesday December 14, 2021 @01:34PM (#29555360)
It's since been published in Science.

https://www.science.org/doi/10.1126/science.abi9069

Re:Omicron variant more resistant to vaccine but causes less... by iso1631 on Tuesday December 14, 2021 @11:53AM (#29553880)
Given that surgical masks stop droplets from spreading as much (especially when you sneeze), and given that bugs spread via droplets, clearly they do something. You may argue on the level of that reduction, or that your right to go out in public without wearing a mask outweighs that reduction, but to just say "masks don't work" is disingenuous.
Re:Omicron variant more resistant to vaccine but causes less... by mitigating on Tuesday December 14, 2021 @11:31AM (#29553472)
" It's pretty obvious that other masks don't work at all"

So a N95 mask works and covering your mouth with a bandana has no effect at all? Not even 10%?

Re:Omicron variant more resistant to vaccine but causes less... by adolph on Tuesday December 14, 2021 @12:51PM (#29554721)
I was putting on two N95s until someone said three was three times as effective so I started wearing three, then one day I did the math myself and don’tcha know, 95% of 95% of 95% is 86%! So I’m back to one mask now, underneath my motorcycle helmet.
Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @11:56AM (#29553927)
Just wear a mask in indoor public places until the pandemic is over.
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @02:55PM (#29556638)
> Just wear a mask in indoor public places until the pandemic is over.

I'm fully vaccinated, so why should I? And when will the pandemic "be over"? Covid is here forever and ever. As long as we keep testing at the level we do, we will always find new variants and always see "spikes" of cases every single winter.

When, specifically, do the states with mask mandates remove them? Why not today? What makes a month better? Or a year? Or never?

Pushing for masks at this stage is arguing we wear masks forever. That isn't a world I care to live in.

Re:Omicron variant more resistant to vaccine but causes less... by wonderwonder on Tuesday December 14, 2021 @12:08PM (#29554122)
Your solution is a good one and makes logical sense but do you think that this pandemic is going to end? It shows no signs of abating currently and the new variant is even more communicable. How does one determine when the pandemic has ended, what is the benchmark? Covid will always be with us going forward. your solution also involves kids wearing masks in school for potentially years and years. I noticed a massive difference in behavior with my youngest kid during his year of wearing a mask in school and after the mandate went away. He went from a reserved almost sad little kid when I picked him up each day back to his prior outgoing happy self after a few weeks. Obviously my experience is anecdotal but I have spoken with other parents that observed the same.
Re:Omicron variant more resistant to vaccine but causes less... by jaywalk on Tuesday December 14, 2021 @03:10PM (#29556824)
No.
Re:Omicron variant more resistant to vaccine but causes less... by AustinDev on Tuesday December 14, 2021 @11:10AM (#29553160)
This may come off wrong but... COVID is not the first virus. Immunosuppressed people for all of human history have been falling victim to the common cold, the flu and other infections most humans can deal with safely. You can't stop the world economy and the benefit that brings to the majority of society to save a fraction of a percentage point of the population that is Immunocompromised.
Re:Omicron variant more resistant to vaccine but causes less... by tn890 on Tuesday December 14, 2021 @11:29AM (#29553438)
Wearing a mask in a supermarket does not "stop the world economy". Americans are borderline insane with the mask mandate
Re:Omicron variant more resistant to vaccine but causes less... by jkubicek on Tuesday December 14, 2021 @12:23PM (#29554313)
Americans are full-on insane with their opposition to mask mandates.
Re:Omicron variant more resistant to vaccine but causes less... by mitigating on Tuesday December 14, 2021 @11:32AM (#29553479)
How does wearing a mask hurt the economy?
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @01:30PM (#29555302)
I personally go out a heck of a lot less with these insane mask mandates. I hate wearing a mask.

Plus many of these people arguing to keep them around forever forget that actual living humans work at these businesses. It takes a lot of privilege to suggest employees should continue wearing masks forever to make a small set of extremely fearful customers feel "safe". I bet 99% of the "pro mask" people on are not in a place requiring them to wear a mask 40 hours a week.

Re:Omicron variant more resistant to vaccine but causes less... by alex-korr on Tuesday December 14, 2021 @02:49PM (#29556549)
Try having a 3 year old child with a speech impediment that has to wear a mask in childcare for 6 hours a day. Does wonders for their ability to communicate.
Re:Omicron variant more resistant to vaccine but causes less... by vkou on Tuesday December 14, 2021 @12:25PM (#29554335)
This may be a simple answer to a simple question - but it doesn't.
Re:Omicron variant more resistant to vaccine but causes less... by unmole on Tuesday December 14, 2021 @11:54AM (#29553890)
What were these people doing every flu season?
Re:Omicron variant more resistant to vaccine but causes less... by jjk166 on Tuesday December 14, 2021 @11:13AM (#29553201)
Hoping it's mild is great. Betting your life it's mild is dumb.
Re:Omicron variant more resistant to vaccine but causes less... by aantix on Tuesday December 14, 2021 @11:19AM (#29553289)
243 deaths per 100,000 in the U.S. (https://coronavirus.jhu.edu/data/mortality).

The death distributions are very clear.

If you're healthy, betting that you would be OK is a very reasonable bet.

Re:Omicron variant more resistant to vaccine but causes less... by r00fus on Tuesday December 14, 2021 @11:37AM (#29553564)
Death is merely the most extreme outcome. Not dying doesn't mean you're OK.

Long COVID is a big deal, and it apparently affects half of those who get COVID [1]. Furthermore, even double-vaxxed, while protected against hospitalization or death, are still at risk (reduced about 50%) for long COVID [2].

Until/unless Omicron has been proven to have less severe long covid symptoms, yeah I'm treating it with the same caution that I'd do with Delta.

[1] https://www.psu.edu/news/research/story/how-many-people-get-... [2] https://www.nature.com/articles/d41586-021-03495-2

Re:Omicron variant more resistant to vaccine but causes less... by timr on Tuesday December 14, 2021 @11:54AM (#29553891)
> Long COVID is a big deal

Long Covid is not a defined term. It comprises everything from "post-hospitalization syndrome" -- which is something that has existed since long before Covid -- to "slight cough for a few weeks". If you're young (under 65) and otherwise healthy, you are highly unlikely to have anything more than a minor illness. Particularly after vaccination.

Here's a paper that might interest you:

https://jamanetwork.com/journals/jamainternalmedicine/fullar...

> In this cross-sectional analysis of 26,823 adults from the population-based French CONSTANCES cohort during the COVID-19 pandemic, self-reported COVID-19 infection was associated with most persistent physical symptoms, whereas laboratory-confirmed COVID-19 infection was associated only with [loss of smell].

In other words, in a large study out of France, the only "long covid symptom" actually correlated with SARS-CoV2 infection was loss of smell. All of the other various symptoms were associated with self-reported illness, but not confirmed illness.

This is a fairly strong argument that "long covid" is at least partly psychosomatic. We'd probably see this more clearly if the various "long covid" studies didn't rely exclusively on self-reporting of symptoms, and mix together all levels of illness.

Re:Omicron variant more resistant to vaccine but causes less... by BrazzVuvuzela on Tuesday December 14, 2021 @12:18PM (#29554237)
Ironically if this is true, then the people loudly handwringing about "long covid" are the ones who are inflicting it on others, by encouraging people to fear it.

To combat this, perhaps we could swap the masks out with gags. /s

Re:Omicron variant more resistant to vaccine but causes less... by in_cahoots on Tuesday December 14, 2021 @12:06PM (#29554091)
That article is so bad it might as well be misinformation. 79% of the people in the study were hospitalized, and the authors did not correct for this.
Re:Omicron variant more resistant to vaccine but causes less... by ceejayoz on Tuesday December 14, 2021 @11:38AM (#29553588)
Some NFL stadiums host 100k people. Would you go to a game if you knew 243 people were going to be randomly executed at it?
Re:Omicron variant more resistant to vaccine but causes less... by aantix on Tuesday December 14, 2021 @11:44AM (#29553685)
Would you attend the game if it were 11 people?

Because that's what you do every time you drive. 11 crash fatalities per 100,000 people.

https://www.iihs.org/topics/fatality-statistics/detail/state...

Re:Omicron variant more resistant to vaccine but causes less... by ceejayoz on Tuesday December 14, 2021 @11:45AM (#29553710)
Driving has benefits.

Getting infected with COVID does not.

Re:Omicron variant more resistant to vaccine but causes less... by mixedCase on Tuesday December 14, 2021 @11:50AM (#29553808)
Except COVID is not the end goal here, it is living a full life in proximity to other human beings that comes with a risk of getting COVID. It is no different in purpose than driving for the most part.
Re:Omicron variant more resistant to vaccine but causes less... by ceejayoz on Tuesday December 14, 2021 @11:52AM (#29553870)
There's a wide spectrum of precautions available. I traveled overseas recently, but I KN95 masked on the plane and tested before departure and on arrival. I felt like I was living a pretty full life in Bora Bora, while also taking steps to ensure the safety of myself and others around me.

Same thing with driving; we have a variety of safety precautions - quite a few of them mandatory - involved that help tilt the cost/benefit balance in our favor.

Re:Omicron variant more resistant to vaccine but causes less... by adolph on Tuesday December 14, 2021 @12:56PM (#29554800)
Why travel anywhere if you are living a flu life in Bora Bora?
Re:Omicron variant more resistant to vaccine but causes less... by ceejayoz on Tuesday December 14, 2021 @01:14PM (#29555084)
Unfortunately, that was my travel destination, so I only got a week there. I heartily recommend a visit.
Re:Omicron variant more resistant to vaccine but causes less... by adolph on Tuesday December 14, 2021 @01:18PM (#29555149)
It’s a pity you and your fellow travelers are destroying the world with your carbon emissions. Good thing you wear a mask tho.
Re:Omicron variant more resistant to vaccine but causes less... by ceejayoz on Tuesday December 14, 2021 @01:20PM (#29555168)
Good news: you can address that, if you're so inclined. https://www.united.com/ual/en/us/fly/company/global-citizens...
Re:Omicron variant more resistant to vaccine but causes less... by adolph on Tuesday December 14, 2021 @05:33PM (#29559047)
With our Eco-Skies® CarbonChoice carbon offset sponsorship program, we’ll purchase carbon offsets on behalf of our customers so all their corporate air travel with us is 100% carbon neutral.

So they will buy carbon indulgences for your corporate trip to Bora Bora but not regular travelers?

Re:Omicron variant more resistant to vaccine but causes less... by ceejayoz on Tuesday December 14, 2021 @05:36PM (#29559082)
It's presented as an option on checkout for any United flight, or you can do it directly after the fact at https://united.conservation.org/. $34 for my round trip.
Re:Omicron variant more resistant to vaccine but causes less... by rajup on Tuesday December 14, 2021 @12:03PM (#29554046)
Getting back to life with COVID with the appropriate amount of precautions and restrictions has benefits. Current hysteria and alarmism shows we are not there yet.
Re:Omicron variant more resistant to vaccine but causes less... by slingnow on Tuesday December 14, 2021 @12:19PM (#29554257)
These statements don't follow from anything anyone has said.

You would need to compare the benefits of driving to the benefits of living a normal life, and compare that to the risks of dying from each.

Why would getting infected with COVID have benefits? What are you trying to say?

Re:Omicron variant more resistant to vaccine but causes less... by landemva on Tuesday December 14, 2021 @01:08PM (#29555010)
'Why would getting infected with COVID have benefits?'

Why do you think you get a choice? Without extreme measures of staying locked up, most everyone will encounter the virus. Why not help your body deal with it by going for a walk today to get some exercise? Life is to live, not eat ourselves to overweight deaths.

Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @01:31PM (#29555317)
> Getting infected with COVID does not.

Going to a live game has benefits. Do those not matter?

Re:Omicron variant more resistant to vaccine but causes less... by megablast on Tuesday December 14, 2021 @12:43PM (#29554591)
Yes. Pollution. Destruction of land. Serious injury. Noise. Urban sprawl.

So many benefits.

Re:Omicron variant more resistant to vaccine but causes less... by throwaway0a5e on Wednesday December 15, 2021 @06:36AM (#29564571)
>Because that's what you do every time you drive. 11 crash fatalities per 100,000 people

This is a ludicrous abuse of statistics. 11 fatalities per 100k people is 11 fatalities per 100k people's worth of trips. That is a few orders of magnitude less than executing 11 people out of every 100k who show up to a stadium.

Re:Omicron variant more resistant to vaccine but causes less... by jonathanstrange on Tuesday December 14, 2021 @12:16PM (#29554218)
That risk is an order of magnitude lower. Moreover, you're not taking that risk "...every time you drive". That risk is much lower, of course, given that most people drive more than once a year.
Re:Omicron variant more resistant to vaccine but causes less... by jdminhbg on Tuesday December 14, 2021 @02:10PM (#29555940)
> Moreover, you're not taking that risk "...every time you drive". That risk is much lower, of course, given that most people drive more than once a year.

The OP comparison of Covid to a football game has the same issue, of course.

Re:Omicron variant more resistant to vaccine but causes less... by kenjackson on Tuesday December 14, 2021 @12:53PM (#29554753)
Correct. It is about 1 death per 100 million miles driven per the table given by the other commenter. Those are actually much better odds than I was expecting!
Re:Omicron variant more resistant to vaccine but causes less... by clairity on Tuesday December 14, 2021 @01:54PM (#29555711)
that doesn’t mean it takes you driving 100m miles to die; that’s a population level statistic. your lifetime chances of death by car is 1 in 100.
Re:Omicron variant more resistant to vaccine but causes less... by kenjackson on Tuesday December 14, 2021 @05:02PM (#29558599)
Right. The 100m miles is more useful because it sets the scale of usage. 1 in 100 odds over your lifetime doesn't say anything about how likely you are to die at any given point in time. It's just that when you do die, there was a 1% chance it was in a car accident.
Re:Omicron variant more resistant to vaccine but causes less... by jdminhbg on Tuesday December 14, 2021 @11:46AM (#29553729)
No NFL stadiums host 100k people. All stadiums in the US with a capacity over 100k are college football stadiums: https://en.wikipedia.org/wiki/List_of_U.S._stadiums_by_capac...

> Would you go to a game if you knew 243 people were going to be randomly executed at it?

Covid-19 deaths are not randomly distributed. We've known this for nearly two years now.

Re:Omicron variant more resistant to vaccine but causes less... by iso1631 on Tuesday December 14, 2021 @11:41AM (#29553643)
I suspect many people would go especially if they knew 243 people were going, the types of people who believe it wouldn't happen to them, only to others (probably someone who made the "bad choices" in life because god/fate/karma/etc)
Re:Omicron variant more resistant to vaccine but causes less... by jjk166 on Tuesday December 14, 2021 @11:51AM (#29553841)
For context, the cancer death rate is 153 per 100,000 in the US, so about 60% of the risk from Covid. Am I living in constant fear of cancer? No. Am I taking reasonable precautions to avoid getting cancer? Yes.
Re:Omicron variant more resistant to vaccine but causes less... by dTal on Tuesday December 14, 2021 @11:37AM (#29553573)
That works out to 1-in-400. 6 times more deadly than base jumping. Not factoring the risk of long-term disability from post-viral CFS.

I'll happily give those odds a miss.

Re:Omicron variant more resistant to vaccine but causes less... by aantix on Tuesday December 14, 2021 @11:41AM (#29553645)
Those (likely) aren't your odds.

Without knowing your specific background, your numbers are probably much less.

E.g. ages 0-17, there's been 644 deaths. Across a cohort with ~75,000,000 people.

https://www.cdc.gov/nchs/nvss/vsrr/covid_weekly/index.htm#Ag...

Re:Omicron variant more resistant to vaccine but causes less... by jonathanstrange on Tuesday December 14, 2021 @12:19PM (#29554247)
Assuming that OP is a teenager or toddler...I guess that could be called "passive-aggressive optimism."
Re:Omicron variant more resistant to vaccine but causes less... by dTal on Tuesday December 14, 2021 @03:40PM (#29557299)
And I've had a HN account for over 8 years... precocious little scamp aren't I!
Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @12:13PM (#29554196)
Depends on what you consider reasonable. Per this study [0] NYC had, as of June 2020, about 100 deaths under age 65 from people without comorbidities. During the same time period there were about 200,000 cases. This made the chance of a healthy person dying from COVID about 1 in 2000.

Given the option, I'm not taking that bet. I wouldn't play Russian roulette even with a 2000-bullet revolver. Especially when there are pretty simple steps I can take to further minimize the risk.

(It would be nice to have more-- and updated-- data than this. If anyone is aware of a source, I'd love to know about it)

That's also discounting other (and possibly not yet known) complications from getting COVID. There might not be much of any, but we it will be some time before we know that so I wouldn't discount that factor in my risk analysis.

Serious measure to mitigate transmission rates still seems like a very reasonable practice, even for healthy people.

[0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327471/

Re:Omicron variant more resistant to vaccine but causes less... by aantix on Tuesday December 14, 2021 @01:19PM (#29555159)
>Depends on what you consider reasonable

Thank-you for acknowledging the subjectivity of Risk Tolerance.

Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @02:27PM (#29556182)
Yep, we all draw our own lines on that. The complicating factor with COVID is that acting on your own higher risk tolerance impacts other people too. That's why we've seen such disagreement in society over the types & level of precautions to take. (Apart from when it is just outright politicized for political gain)
Re:Omicron variant more resistant to vaccine but causes less... by _pmf_ on Tuesday December 14, 2021 @11:44AM (#29553682)
> Betting your life it's mild is dumb.

But keeping the panic dialed up to 11 for two years is very healthy.

Signed, someone who probably now has a cardiac neurosis.

Re:Omicron variant more resistant to vaccine but causes less... by mrtksn on Tuesday December 14, 2021 @12:36PM (#29554486)
Just look at well vaccinated populations like UK or Spain and then look at not well vaccinated like Bulgaria to see if it holds.

Unfortunately, in Bulgaria you see that the size of the deaths wave still follows the size of the infection wave.

The “no vulnerable people to die are left” hypothesis doesn’t hold. Those who survived survived because they were lucky, careful or vaccinated. It’s not true that the virus burned through the population and the remaining are the immune or resilient survivors.

Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @12:54PM (#29554769)
The UK has basically indicated that it is going to be bad and are relying on boosting before the new year to blunt the impact. If that doesn't work, lock downs are coming..
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @03:48PM (#29557447)
> If that doesn't work, lock downs are coming..

If they lock down again, they'll lock down every single winter from here on out. Lockdowns in a post-vaccine world are complete madness.

Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @06:11PM (#29559443)
I dunno, masks seem pretty effective as are capacity limits. That and rapid testing before gathering seems like a pretty good plan.
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @06:57PM (#29559903)
Mask and capacity limits until when? And why? What problem is being solved now? What’s the goal?
Re:Omicron variant more resistant to vaccine but causes less... by mrtksn on Tuesday December 14, 2021 @08:16PM (#29560716)
Why I’m sensing a tone of desire to cancel the virus? As if, not fun anymore let’s do something else kind of canceling.

A few months back I was in Bulgaria, where the majority of the population is antivaxx virus deniers mask sceptics. It’s true that mask free virus free worry free life is much better, it was liberating to be in Bulgaria. However, at the same time everyone knew someone who died from covid. Much more than Turkey, where I have been since the start of the pandemic.

The situation we are in is not a choice. The virus is real, the damage is real and we can’t simply refuse to play. We can but a lot of people will die and I’m not convinced that this is the way to go.

I bet, when the things start getting real with other issues like the global warming, the inconveniences will create similar reactions. I appreciate the drive, the desire for freedom and convince but these things happen to people all the time when they fail to address the slow moving issues beforehand.

Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @08:39PM (#29560945)
The situation we are in is absolutely a choice. We can choose right now today to move on from Covid. All we have to do is decide to stop being afraid of it. Accept the risk and move on.

Everything we’ve done in the last two years is not caused by the virus but our reaction to the virus.

PS: eventually even the most hardcore fearful will have no choice but to move on. Omicron is not the last variant and Covid will be with us forever. Expecting every member of society to treat Covid as if it is the only problem from here on out is not going to happen.

Get your vaccines. Stop being scared and move on. It’s quite literally as simple as that.

Re:Omicron variant more resistant to vaccine but causes less... by mrtksn on Tuesday December 14, 2021 @09:03PM (#29561135)
Do you understand that your level of fear is irrelevant from virus perspective? Sars-cov-2 doesn’t care about your feelings.

We will eventually move on, the idea is to do it with least damage possible. People moved on from the plague, the black death ve will move on. It’s just doesn’t need to lose so many people in the name of conspiracy theories and inconvenience.

The handling of the situation is different everywhere. It’s a management issue, not really a virus issue.

Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @09:24PM (#29561294)
> Do you understand that your level of fear is irrelevant from virus perspective? Sars-cov-2 doesn’t care about your feelings.

The way you talk scares me more than the virus. It is so authoritarian and creepy. So many of my tech worker colleagues talk the same way. It’s abuse. People that talk your way are the kinds of people that commit grave atrocities in the name of some cause you are 100% bought into. You do not have the moral high ground you think you do. Stop now before you let very evil people use you to commit very bad things to your fellow humans.

You’ve already allowed your government to destroy our kids, caused old folks to die alone in care homes, gutted the working class, transferred enormous amounts of wealth to the richest in society, and divided the population in a way never seen before. You are committing great evil and you foolishly believe you are doing it for a proper cause. You aren’t.

Covid ends when you personally decide it does. Covid has no feelings. It’s a virus. It does virus stuff. It’s a part of nature just like earthquakes or tornadoes. We have very little control over it. Accept that and move on.

End your fear and Covid is no longer a problem. It is literally as easy as that. Nobody has to “accept” the virus requires them to sacrifice their very short amount of time on this earth unless they allow it to. And anybody who tells them otherwise is not to be trusted at all, for they have nobodies interest in mind.

Re:Omicron variant more resistant to vaccine but causes less... by mrtksn on Wednesday December 15, 2021 @01:19AM (#29562709)
The virus can’t have feelings, it’s not even a living thing and will not react to your courage. If that’s authoritarian so be it, the meaning of the word must have changed.

You know what’s part of the nature? lions, crocodiles and sharks and yet I’m not going to let them eat me. Earthquakes are natural too and you build accordingly, actually the evil governments even implemented building codes for it. 20 years ago I survived an earthquake that wiped out the neighbourhood because the previous governments couldn't bother to be evil and authoritarian over building standards.

What's up with this obsession with naturalism and personification of events?

Re:Omicron variant more resistant to vaccine but causes less... by GeekyBear on Tuesday December 14, 2021 @12:04PM (#29554071)
> Can we never, not even once, be a little optimistic?

I'm optimistic.

A version of Covid that is much more contagious, but less likely to be severe is a great way to get the immune system of the vaccine avoidant trained on how to recognize and fight Covid.

For those who have already been vaccinated, a mild breakthrough infection would serve the same function as a booster shot.

Re:Omicron variant more resistant to vaccine but causes less... by pbourke on Tuesday December 14, 2021 @12:29PM (#29554390)
30% less severe with twice the rate of spread does not seem like a good tradeoff. You have an exponential increase in cases but a linear reduction in hospital admissions.
Re:Omicron variant more resistant to vaccine but causes less... by macintux on Tuesday December 14, 2021 @12:37PM (#29554499)
> For those who have already been vaccinated, a mild breakthrough infection would serve the same function as a booster shot.

Except booster shots don’t infect other people.

Re:Omicron variant more resistant to vaccine but causes less... by JamesBarney on Tuesday December 14, 2021 @12:33PM (#29554450)
The doctor who found it, isn't a psychic. She doesn't have any information the rest of us don't. She's just describing her personal experience.

And her experience is entirely consistent with Omicron appearing less virulent because it's infecting the previously infected and vaccinated who already have some degree of immunity.

Re:Omicron variant more resistant to vaccine but causes less... by mohanmcgeek on Tuesday December 14, 2021 @12:37PM (#29554498)
> because it's infecting the previously infected and vaccinated who already have some degree of immunity.

The doctor isn't a psychic but how do _you_ know this

Re:Omicron variant more resistant to vaccine but causes less... by JamesBarney on Tuesday December 14, 2021 @01:26PM (#29555247)
How do I know "her experience is entirely consistent with Omicron appearing less virulent because it's infecting the previously infected and vaccinated who already have some degree of immunity."

1. We know that break through infections are less serious than infections to the unvaccinated and uninfected. 2. We determine virulence by # of hospitalizations (or other serious outcome) / # of infections 3. If we add more infections that don't have serious outcomes (because they are break through cases) that greatly increases the denominator without affecting the numerator. 4. This is how you could have Omicron be just as virulent as the original but look less virulent to a doctor. (Because of the break through cases)

Does that make sense?

Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @12:52PM (#29554728)
Hope is not a strategy.
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @01:32PM (#29555329)
Nor is irrational panic
Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @02:35PM (#29556309)
Reality exists somewhere in the middle where we work together on rational mitigation strategies.
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @02:57PM (#29556665)
We have mitigation strategies. Vaccines. We've had them for a year. Anybody can get them. Boosters even. You can even mix & match your preferred make & model at this point!

We don't need any further mitigation strategies. Vaccines were the only real mitigation strategy we ever had.

Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @03:44PM (#29557365)
The medical and scientific consensus is that vaccines alone are not enough.
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @03:55PM (#29557565)
Could you imagine a company where lawyers had complete control over product development and the entire company designed their goods around whatever the lawyers said? Every square inch of the product would be covered in legal disclaimers, everything would have foam padding on the corners, and the box it came in would have you sign a 40 page document before you could even open it. I have no clue how the actual product might function but whatever it does, there is no way its failure would result in a lawsuit; which means it probably doesn't work very well at all.

Sometimes I feel this is what people want when they say we should be listening to "medical and scientific" people. They want us to build society around the advice of exactly one profession to the exclusion of everything else.

It takes way more than just a very narrow expert to run a society. For two years we've handed the keys over to exactly one form of expert and completely ignored every other form of expertise.

These "medical and scientific" folks you talk of can yell "not enough" until they run out of air but that doesn't mean we should listen to them. Of course they are gonna say "it isn't enough"! That is their job! That doesn't mean we should to listen to their advice.

It may come as a surprise to some people but at some point you have to move on from covid no matter what these "experts" say. There are vastly more problems with the world than one specific form of illness.

This blind adherence to a small set of "medical experts" is completely myopic and is resulting in a cure that is much worse than covid ever was. We've had a vaccine for a year. You can mix & match boosters at this point. Party is over. Covid is here to stay. Move on, people.

Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @04:18PM (#29557937)
If COVID is here to stay, we still need mitigation strategies and for people to follow them.
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @04:38PM (#29558253)
what would those mitigation strategies be?
[dead]
Re:Omicron variant more resistant to vaccine but causes less... by tannisphere4 on Tuesday December 14, 2021 @11:16AM (#29553250)
Someone out there is doing a study on meta-communication during COVID. The internalization of dominant narratives on social media is such an unspoken axiom, that merely SUGGESTING optimism results in a flurry of "we can't be sure!" finger-waves.

One could hypothesize that those who derive greater self-esteem or self-worth from social dynamics would engage in behaviors where the long-run probability of increasing self-esteem is higher. In other words, the most adaptive posts on both sides of a social media debate would be those which: A) maximally increase self-esteem via ingroup loyalty, and B) cause the debate to be prolonged or not resolved, thereby increasing the duration of A. The "we can't be sure" defense in response to optimism is B.

Re:Omicron variant more resistant to vaccine but causes less... by legulere on Tuesday December 14, 2021 @10:45AM (#29552814)
Of course we should be optimistic that omicron and variants that will follow will be less severe.

But that hope should not be treated as a fact like the headline does.

Another hope could be that omicron is actually not as virulent as delta, but only spreads so fast in South Africa, because people can get reinfected.

Re:Omicron variant more resistant to vaccine but causes less... by manjana on Tuesday December 14, 2021 @11:17AM (#29553266)
> Another hope could be that omicron is actually not as virulent as delta, but only spreads so fast in South Africa, because people can get reinfected.

It's seeing a pretty explosive growth rate in Denmark.

https://sum.dk/ministeren/sociale-medier-arkiv/2021/december...

https://www.ssi.dk/-/media/cdn/files/covid19/omikron/statusr...

Re:Omicron variant more resistant to vaccine but causes less... by ljm on Tuesday December 14, 2021 @10:40AM (#29552747)
> COVID clearly isn't going away at this point, so by all means try to replace it with something weaker!

Probably naive to think we could totally eradicate it within a couple of years, particularly as far as vaccine fearmongering is concerned. Would be nice to see it join Smallpox and Polio though.

That said, we've accepted an annual winter uptick in flu infections and we just tell people most vulnerable to get their yearly flu jab; less vulnerable folks can stay at home for a bit and manage the symptoms. If that's what we have to do for covid every winter then so be it.

I would still call that a victory overall.

Re:Omicron variant more resistant to vaccine but causes less... by azekai on Tuesday December 14, 2021 @11:06AM (#29553101)
>Probably naive to think we could totally eradicate it within a couple of years, particularly as far as vaccine fearmongering is concerned. Would be nice to see it join Smallpox and Polio though.

We would have to completely redesign our current method of vaccination, then. We do not have a sterilizing vaccine for COVID (like we did for smallpox and polio). The current vaccines all use spike proteins to prepare a body's antibodies against the main infection tool of the COVID virus. This method indirectly prevents the virus from efficiently infecting cells in vaccinated hosts, but it does not and cannot eradicate the virus.

Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @11:53AM (#29553885)
Huh? I would suggest you read: https://www.theatlantic.com/science/archive/2021/09/steriliz...

We don't actually have sterilizing vaccines for smallpox or polio either.

Re:Omicron variant more resistant to vaccine but causes less... by azekai on Tuesday December 14, 2021 @05:23PM (#29558930)
That article strikes me as largely playing a semantic game. From the article:

>The classic tale of sterilizing immunity unfolds something like this: A pathogen attempts to infiltrate a body; antibodies, lurking in the vicinity thanks to vaccination or a previous infection, instantly zap it out of existence, so speedily that the microbe can’t even reproduce. No symptoms manifest, and most of the body’s immune cells never get involved, a bit like an intruder smacking up against an electric fence around a building, leaving the security guards inside none the wiser.

and

>This is a very neat story. And it is “almost impossible to prove,” Mark Slifka, an immunologist and vaccine expert at Oregon Health & Science University, told me. To show sterilizing immunity, researchers have to demonstrate that an infection never occurred—a big ask, considering that microbiologists can’t even agree on what an infection actually is.

If that is the definition used, yes, you are right. It is also basically useless as a term, as it is 'almost impossible to prove.' If you wish to use another term, we can do that. Instead of sterilizing, I could simply say 'highly effective.' Suffice to say, the mechanisms used by the COVID vaccine and the polio vaccine are very different. At most, the polio vaccine only included 3 strains (or variants)- the Salk vaccine, the first, only targeted type 1, but two more were added later over the course of years.

All of this is to say- the highly effective polio vaccine works because there are very few polio variants and people are immunized against them directly.

The COVID vaccine does not make one immune to the virus, or immune to the spike protein. The presence of the spike protein in the vaccine provokes an autoimmune response in the form of antibodies that will target that spike protein. This is somewhat effective, and a clever 'hack' that allows us a measure of protection. However, different spike proteins can be used by different variant viruses.

I am not antivaccine, and while autoimmune systems can be fairly complex, it is certainly worth discussing. Frankly I find the obfuscation and sloppy, ideological reporting to be frustrating. On all sides I see a lack of rigor and emotional attempts at control.

Re:Omicron variant more resistant to vaccine but causes less... by tbihl on Tuesday December 14, 2021 @06:21PM (#29559541)
Sometimes I feel like I repeat myself.

Would someone who is flagging this comment please, instead, respond to it? If it is so trivially dismissed, please show the rest of us.

Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @10:02PM (#29561557)
The argument that this is a semantic game is not a very good one. The whole point of the article is to demonstrate that there really is no such thing as a sterilizing vaccine; As our scientific knowledge and technology has improved over the years we see that.
Re:Omicron variant more resistant to vaccine but causes less... by tbihl on Tuesday December 14, 2021 @11:21AM (#29553317)
Would someone who is flagging this comment please, instead, respond to it? If it is so trivially dismissed, please show the rest of us.
Re:Omicron variant more resistant to vaccine but causes less... by CorrectHorseBat on Tuesday December 14, 2021 @11:49AM (#29553791)
What other target would be better for a sterilizing vaccine?
Re:Omicron variant more resistant to vaccine but causes less... by lostlogin on Tuesday December 14, 2021 @12:34PM (#29554454)
Malaria.
Re:Omicron variant more resistant to vaccine but causes less... by bagels on Tuesday December 14, 2021 @11:31AM (#29553468)
Is it possible for one to be developed?
Re:Omicron variant more resistant to vaccine but causes less... by kiba on Tuesday December 14, 2021 @10:46AM (#29552842)
That said, we've accepted an annual winter uptick in flu infections and we just tell people most vulnerable to get their yearly flu jab; less vulnerable folks can stay at home for a bit and manage the symptoms. If that's what we have to do for covid every winter then so be it.

Accepted? I would call that normalizing as well. According to an estimate, about 290,000 to 650,000 globally died of the flu each year.[1]

Normalization means it's a problem out of mind out of sight. We stop demanding these problems to be solved.

1. https://www.who.int/news/item/13-12-2017-up-to-650-000-peopl...

Re:Omicron variant more resistant to vaccine but causes less... by rkk3 on Tuesday December 14, 2021 @12:01PM (#29554022)
At a certain point we accept the tradeoffs and get on with it. A few hundred thousand people die of the flu every year. So what? It's tragic, but that is life.
Re:Omicron variant more resistant to vaccine but causes less... by kiba on Tuesday December 14, 2021 @12:35PM (#29554471)
Normalization is not about accepting tradeoff. It's accepting defeat.

At some point, drastic measures start being worse than the disease. It doesn't mean we should ignore the few hundred thousand death.

Re:Omicron variant more resistant to vaccine but causes less... by rkk3 on Tuesday December 14, 2021 @02:20PM (#29556085)
56 Million people die a year. There are vaccine's and treatments available for the Flu. The deaths aren't 0 but don't think it's something to moralize about and call a defeat.
Re:Omicron variant more resistant to vaccine but causes less... by systemvoltage on Tuesday December 14, 2021 @11:07AM (#29553116)
If it means more lockdowns and more restrictions, more government powers; absolutely normalize COVID. We have given up enough.
Re:Omicron variant more resistant to vaccine but causes less... by kiba on Tuesday December 14, 2021 @11:18AM (#29553267)
Just because our economy cannot withstand further lockdowns and restrictions doesn't mean that the normalization of COVID is any more excusable. It just means we failed.
Re:Omicron variant more resistant to vaccine but causes less... by selectodude on Tuesday December 14, 2021 @11:47AM (#29553753)
It has nothing to do with the economy. Humans are social creatures. You can pay me $100,000/mo to sit in my house indefinitely and I can almost guarantee you it'll end in depression and suicide.
Re:Omicron variant more resistant to vaccine but causes less... by systemvoltage on Tuesday December 14, 2021 @12:15PM (#29554205)
To take this to extreme: We’ve failed to solve deaths. We should have solutions to aging and indefinite life.

Since we have 100% death ratio, show us your health history along with your verifiable ID. We are the ministry of Truth and Safety.

In all seriousness: We need to push back on robbing of civil liberties. No one cared to check for flu vaccine. It should be the same for COVID now that it’s getting weaker and it won’t end forever.

Re:Omicron variant more resistant to vaccine but causes less... by capdeck on Tuesday December 14, 2021 @10:49AM (#29552871)
> I would still call that a victory overall.

Humanity declared victory over every single pathogen to date (eradicated, contained or seasonal) because we are still here and thriving. We should go on with our lives.

Re:Omicron variant more resistant to vaccine but causes less... by notreallyserio on Tuesday December 14, 2021 @11:08AM (#29553137)
In the mean time we should do whatever we can to avoid filling hospitals to capacity.
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @01:33PM (#29555349)
Maybe build more hospitals? I mean, in march of 2020 we expressly locked down to build up healthcare capacity. Where is it?
Re:Omicron variant more resistant to vaccine but causes less... by jaywalk on Tuesday December 14, 2021 @03:13PM (#29556891)
It's almost completely a staffing issue at this point. Good thing we fired a bunch of healthcare workers because they didn't want to get vaccinated!
Re:Omicron variant more resistant to vaccine but causes less... by spookthesunset on Tuesday December 14, 2021 @03:32PM (#29557183)
> It's almost completely a staffing issue at this point

So these politicians should treat this like an emergency and drive dumptrucks of money up to healthcare staff not working and get them back. Get nursing students. Do whatever it takes. Think outside of the box. This is supposed to be an emergency, is it not?

I mean, if it was an emergency and healthcare was truly an issue, why aren't those hospital tents and hospital ships docked in the harbor of every major city? "Lack of staff" is just an excuse in an emergency. You work around it. Make it happen. It's an emergency, right?

And if it isn't an emergency, why are we mandating anything at all? Shouldn't we all be going about our lives like we did prior to march 2020? If it isn't an emergency why are governments still using emergency powers to push mandates onto citizens instead of actually dealing with hospital shortages?

None of this makes any sense at all when you really start thinking about it. Absolutely none of it... Never did, never will...

Re:Omicron variant more resistant to vaccine but causes less... by capdeck on Tuesday December 14, 2021 @01:22PM (#29555194)
... or maybe we should stop closing hospitals during the pandemic?

[US Closing Hospitals At Record Pace During Pandemic - YouTube](https://www.youtube.com/watch?v=Zz46ZQSRdRE)

Re:Omicron variant more resistant to vaccine but causes less... by rajup on Tuesday December 14, 2021 @12:06PM (#29554086)
Sounds good. 2 years on with enough vaccines and antiviral pills on the way if you still believe hospitals are "filled to capacity", I'd like what you're smoking.
Re:Omicron variant more resistant to vaccine but causes less... by isoskeles on Tuesday December 14, 2021 @12:39PM (#29554540)
I’m smoking a wadded-up copy of that Rolling Stone article about gunshot victims waiting for the ER.
Re:Omicron variant more resistant to vaccine but causes less... by sjwalter on Tuesday December 14, 2021 @11:21AM (#29553309)
Sure, but hospitals are run at a level to hit peak capacity at the point when vitamin D deficiency peaks.

Here's LA County using overflow tents in 2018 because the flu season was particularly bad: https://www.latimes.com/local/lanow/la-me-ln-flu-demand-2018...

So it's not like this is some new threat. "2 weeks to flatten the curve" came along with some understanding that hospitals would increase their resources. Instead, in many states, they've spent more time working out which unvaccinated staff to fire and how than they have increasing staffing levels.

Re:Omicron variant more resistant to vaccine but causes less... by jatone on Tuesday December 14, 2021 @10:43AM (#29552790)
I havent seen any evidence covid is seasonal. it may become seasonal. but nothing in the past 2 years as indicated it is.
Re:Omicron variant more resistant to vaccine but causes less... by tbihl on Tuesday December 14, 2021 @11:19AM (#29553288)
Just so other commenters can understand: are you saying that you haven't seen the charts with enormous spikes on them every time a place enters a cold season? Or that you find them to be uncompelling for some (as yet undisclosed) reason?
Re:Omicron variant more resistant to vaccine but causes less... by unmole on Tuesday December 14, 2021 @11:52AM (#29553873)
The second wave hit India at the height of summer. That outlier is big enough for me to be sceptical.
Re:Omicron variant more resistant to vaccine but causes less... by coolspot on Tuesday December 14, 2021 @12:00PM (#29553994)
Have you seen infection/death charts? It peaks in winter and at its minimum in summer.
Re:Omicron variant more resistant to vaccine but causes less... by unmole on Tuesday December 14, 2021 @12:39PM (#29554533)
Have you seen the charts for India?
Re:Omicron variant more resistant to vaccine but causes less... by selectodude on Tuesday December 14, 2021 @02:02PM (#29555843)
Have you seen the charts for literally the rest of the world?

You're picking an outlier as proof that its not seasonal. Others may say it's the exception that proves the rule.

Re:Omicron variant more resistant to vaccine but causes less... by unmole on Tuesday December 14, 2021 @02:17PM (#29556032)
> Have you seen the charts for literally the rest of the world?

I just did. There are no discernable spikes coinciding with cold weather for India, Brazil, the UK or Russia.

Re:Omicron variant more resistant to vaccine but causes less... by selectodude on Tuesday December 14, 2021 @02:34PM (#29556298)
I decided to check Brazil really quickly and there's a very steep drop off once summer hit. I don't even need to bother with the UK.
Re:Omicron variant more resistant to vaccine but causes less... by unmole on Tuesday December 14, 2021 @02:47PM (#29556498)
The steep drop off starts of in July which in Brazil is winter.
Re:Omicron variant more resistant to vaccine but causes less... by Izkata on Tuesday December 14, 2021 @06:18PM (#29559515)
Most of Brazil is pretty temperate year-round, so they don't really have a very sharp flu season, but what they do have typically peaks around June, which fits with when the covid drop started.

https://en.wikipedia.org/wiki/Flu_season#Timing -> https://academic.oup.com/aje/article/165/12/1434/125289

> In the Fourier analysis, the seasonality of influenza in Brazil was characterized by a semiannual pattern, peaking in the winter month of June (amplitude = 27 percent), with a second, smaller peak during the summer (January; amplitude = 13 percent; figure 2).

Re:Omicron variant more resistant to vaccine but causes less... by roywiggins on Tuesday December 14, 2021 @11:31AM (#29553460)
It won't join smallpox because it has lots of animal reservoirs.

https://www.cnn.com/2021/11/17/health/covid-deer-animals/ind...

Re:Omicron variant more resistant to vaccine but causes less... by algo646464 on Tuesday December 14, 2021 @12:39PM (#29554537)
I don't think that it is misleading. The severity of a disease is relative to the current situation.

For example, it could be the case that Omicron is actually less infectious than the original variant, when compared in the setting of 2020. It spreads faster today because, (i) because of preexisting immunity most cases are very mild, and so lots of people become unwitting carriers, (ii) people have gone back to normal behavior after vaccination, and (iii) the vaccines inhibit the other variants much more than Omnicron. So Omicron gets more opportunities to infect and spread. Of course, all this is just conjecture and could be true or false.

What matters from a practical point of view is that, Omnicron is less severe in the general population today(for various reasons), as compared to the original strain back in 2020.

Re:Omicron variant more resistant to vaccine but causes less... by croes on Tuesday December 14, 2021 @12:46PM (#29554643)
It is misleading if you compare a country with 80% infection rate with countries with much fewer infections. If the milder cases are because of previous infections it could be a hard hit for unvaccinated first timers.
Re:Omicron variant more resistant to vaccine but causes less... by gruez on Tuesday December 14, 2021 @12:52PM (#29554732)
> I don't think that it is misleading. The severity of a disease is relative to the current situation.

I think it is misleading. AIDS is much more survivable in "the current situation" because of various drug advances we made in the past few decades. Does that mean 2021 AIDS is "less severe" than 90s AIDS? I guess you could claim it's technically less severe, but the wording definitely suggests it's something about the virus, rather than the environment.

Re:Omicron variant more resistant to vaccine but causes less... by themgt on Tuesday December 14, 2021 @01:11PM (#29555046)
So if we had:

* variant "D" that kills 1% of the 20% of the population that isn't seropositive

* variant "O" that kills 1% of the 20% of the population that isn't seropositive and 0.2% of the 80% of the population that is seropositive

The takeaway is "good news everyone, variant O is less severe!"

Re:Omicron variant more resistant to vaccine but causes less... by elsherbini on Tuesday December 14, 2021 @10:35AM (#29552659)
Another quote from the press-release of the study:

>“Epidemiological tracking shows a steep trajectory of new infections, indicating Omicron’s rapid spread, but so far with a flatter trajectory of hospital admissions, possibly indicating lower severity,” explains Dr Noach. “This lesser severity could, however, be confounded by the high seroprevalence levels of SARS CoV-2 antibodies in the general South African population, especially following an extensive Delta wave of infections.” [1].

So, to actually make the comparison we'd need to compare new Delta infections with new Omicron infections time-matched, comparing people who were seronegative to start with. This would be really hard to do in South Africa since there is a high proportion of seropositive people.

[1] https://www.discovery.co.za/corporate/news-room

Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @11:31AM (#29553467)
The study adjusted for vaccine status [0] but was still comparing things to the initial wave in 2020, which is strange and I would like to know their justification for that.

For a bit more of an apples-to-apples comparison they should be comparing omicron hospitalization & fatality rates to those of non-omicron variants over the same period of time. It doesn't look like they've done that, and I'm not aware of a study that has systematically done this (yet).

It would certainly be a holiday-season gift if we shifted to a more virulent but less serious variant, but I'll hold out for a bit more information before I completely buy into that narrative. That can be difficult: people want to believe some good news here. Heck, my initial gut reaction was to push back against your objections but my career has trained me to resist that sort of thing. It won't be good for the erosion of trust in the media if they've jumped the gun on this and Omicron doesn't turn out the way we hope it will.

https://www.discovery.co.za/corporate/news-room

Re:Omicron variant more resistant to vaccine but causes less... by JamesBarney on Tuesday December 14, 2021 @12:39PM (#29554526)
Did they also adjust for previous infection?
Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @12:43PM (#29554602)
Not that I can tell (EDIT: They did, see comment further down) This seems to be research release by PR, not a published study. Although even if they adjusted for prior infections they should still be comparing comparable time periods. It is really odd if they didn't, and odd if they did do it but the results weren't included in the release. The initial 2020 wave is a reasonable baseline, but not a good measure of relative risk factors between variants right now especially because 2020 didn't include Delta.
Re:Omicron variant more resistant to vaccine but causes less... by ___q on Tuesday December 14, 2021 @12:44PM (#29554605)
Yes

> For individuals who have had COVID-19 previously, the risk of reinfection with Omicron is significantly higher, relative to prior variants.

Re:Omicron variant more resistant to vaccine but causes less... by JamesBarney on Wednesday December 15, 2021 @01:35AM (#29562798)
It also says the specifically did not adjust for previous infection when calculating severity.
Re:Omicron variant more resistant to vaccine but causes less... by ineedasername on Tuesday December 14, 2021 @02:27PM (#29556189)
Thanks-- I missed that in my read through.
Re:Omicron variant more resistant to vaccine but causes less... by nyokodo on Tuesday December 14, 2021 @10:38AM (#29552717)
> It is possible that Omicron is just as severe and that the effect in the study is because a large percentage of the population had some immunity from a previous infection or vaccine.

All viruses are severe if you have no immune protection from them. A small number of people die from the cold every year. The only thing that matters is how severe the infection is given the immunity you have.

Re:Omicron variant more resistant to vaccine but causes less... by Sharlin on Tuesday December 14, 2021 @10:57AM (#29552952)
Well, yes, but if you’re naively comparing the severity of omicron infections to that of the previous strains then that’s just apples and oranges because the degree of immunization in the population is not the same, even if you only consider non-vaccinated people.
Re:Omicron variant more resistant to vaccine but causes less... by nyokodo on Tuesday December 14, 2021 @02:46PM (#29556484)
> severity of omicron infections to that of the previous strains then that’s just apples and oranges

Comparing the severity of the viral strains on some objective scale, if that’s even possible, is at best an academic curiosity. Severity comparisons only really matter in giving us an accurate idea of how likely severe illness and death will be so that individuals, families, and public health officials can make any changes necessary.

Re:Omicron variant more resistant to vaccine but causes less... by janmo on Tuesday December 14, 2021 @10:23AM (#29552522)
Also, most people who would have died of Covid in South Africa already died during the Beta and then the Delta wave.
Re:Omicron variant more resistant to vaccine but causes less... by drcongo on Tuesday December 14, 2021 @11:48AM (#29553766)
If you want misleading titles, try this [0] from the Guardian. Every single other news outlet covering this study managed an accurate headline.

[0] https://www.theguardian.com/world/2021/oct/28/covid-vaccinat...

Re:Omicron variant more resistant to vaccine but causes less... by jmull on Tuesday December 14, 2021 @11:38AM (#29553583)
The headline looks good to me.

Few headlines work without context so what we want is for them to choose the most obvious, pertinent context. I think we all care a lot more about what Omicron means to us now, not what it would have meant if it were the main variant at the start of the pandemic.

And, of course, anyone who cares about the topic should read past the headline.

Re:Omicron variant more resistant to vaccine but causes less... by skeeter2020 on Tuesday December 14, 2021 @11:20AM (#29553301)
It's also early days for the new variant. I would love and do hope this is true, but it's previously take weeks and months to start seeing fatalities after the first reported cases, so it may be too early to make this statement yet; waiting for the law of big numbers to kic in.
Re:Omicron variant more resistant to vaccine but causes less... by toss1 on Tuesday December 14, 2021 @11:47AM (#29553749)
Yup, it is definitely too soon to be sure of anything like this headline, and that's the word of the leading epidemiologists I follow.

Plus, this combination could be a lot WORSE for the hospital capacity situation.

Even if the virulence/severity is only a fraction, the severe consequences will still grow exponentially, just further to the right on the curve.

Meanwhile, the curve will grow a lot faster to the top of the graph because the greater exponential growth among both the unvaxed and the vaccinated.

So, higher percentage of severe cases and lower transmisability would be less bad — fewer sever cases and much greater trensmissability is almost the worst case.

Re:Omicron variant more resistant to vaccine but causes less... by notabee on Tuesday December 14, 2021 @10:40AM (#29552743)
Additionally, severe illness and deaths are a lagging indicator. Cases are going to wildly outpace those figures because of how transmissable this is, until they don't. Deaths especially often take months from onset.
Re:Omicron variant more resistant to vaccine but causes less... by simonh on Tuesday December 14, 2021 @10:57AM (#29552959)
Hence the credulous articles about how India was 'special' when the virus first started spreading there because there were so few fatalities. Turns out it was spreading incredibly fast so cases were surging, but it took a month or more for the wave of deaths to follow. But follow it absolutely did.
Re:Omicron variant more resistant to vaccine but causes less... by colordrops on Tuesday December 14, 2021 @11:24AM (#29553359)
Why is it ok to to be skeptical of findings if they are optimistic when it comes to covid, but if you challenge a pessimistic finding you are an anti-science anti-vaxxer piece of work? Let's be consistent here.
Re:Omicron variant more resistant to vaccine but causes less... by rich_sasha on Tuesday December 14, 2021 @10:23AM (#29552519)
It would be nice, and seemingly feasible, if they could compare to recent Delta infections (or even current one, seeing as both variants are present right now). Presumably any kind of acquired immunity is more comparable to 3 months ago vs. 21 months ago.

It could still be that among people infected with Omicron, there is a larger proportion of vaccinated people, due to vaccines being less efficient, but that's still a better yardstick.

Re:Omicron variant more resistant to vaccine but causes less... by fanzhang on Tuesday December 14, 2021 @11:48AM (#29553773)
Technically anything is "possible" -- but what does the Bayesian weight of evidence say at this point?
Re:Omicron variant more resistant to vaccine but causes less... by foolfoolz on Tuesday December 14, 2021 @10:22AM (#29552507)
a large percentage of the planets population has some immunity from previous infection or vaccination
Re:Omicron variant more resistant to vaccine but causes less... by bingohbangoh on Tuesday December 14, 2021 @11:24AM (#29553358)
Weird, I thought that the natural immunity from COVID-19 wasn't as strong as the vaccine.
Re:Omicron variant more resistant to vaccine but causes less... by lanevorockz on Tuesday December 14, 2021 @10:37AM (#29552701)
You can easily disprove your theory by using the number of vaccinated vs unvaccinated that were exposed. We are talking about severity and not spread, that is easily done.
Re:Omicron variant more resistant to vaccine but causes less... by simonh on Tuesday December 14, 2021 @10:52AM (#29552904)
It's not the commenter's theory, it's the theory proposed in the article itself and that the commenter quoted. It's somewhat possible to account for the vaccination rate, but not really for resistance due to prior exposure because there are so many unknown variables in that.
Re:Omicron variant more resistant to vaccine but causes less... by lee on Tuesday December 14, 2021 @11:51AM (#29553835)
Additionally, the demographics of South Africa are different too. The median age is significantly lower than most Western countries.
Re:Omicron variant more resistant to vaccine but causes less... by timr on Tuesday December 14, 2021 @11:35AM (#29553528)
> The title is misleading.

Just because you disagree with something does not make it "misleading". The question of prior immunity is not unknown, is an obvious question, and in fact is mentioned in the article and discussed in the study.

The title accurately reflects the contents of the study. I have many issues with Washington Post's coverage of Covid, but this is actually fair.

Re:Omicron variant more resistant to vaccine but causes less... by bluGill on Tuesday December 14, 2021 @11:37AM (#29553562)
That is still misleading. We don't actually have enough evidence to make such bold claims because the unknowns exist.
Re:Omicron variant more resistant to vaccine but causes less... by timr on Tuesday December 14, 2021 @11:37AM (#29553569)
Again: Just because you disagree with something does not make it "misleading". Your opinion is not truth.

No research paper stands alone, and we never have all context on a given question. You disagree with the conclusion for reasons -- that's fine. Make your arguments, and see if you can convince people. That's how science works.

Re:Omicron variant more resistant to vaccine but causes less... by epgui on Tuesday December 14, 2021 @12:03PM (#29554052)
Biochemist here, you are spot on. I came here to say the same thing.
Re:Omicron variant more resistant to vaccine but causes less... by sjg007 on Tuesday December 14, 2021 @11:58AM (#29553959)
Also the 20% increase in child hospitalizations is no joke.
Re:Omicron variant more resistant to vaccine but causes less... by xyproto on Tuesday December 14, 2021 @11:18AM (#29553270)
There are plenty of people in intensive care, though.
Re:Omicron variant more resistant to vaccine but causes less... by sjwalter on Tuesday December 14, 2021 @11:23AM (#29553349)
There always are. Average hospital staffing and resource levels mean at its minimum ICUs are at ~78% capacity. Come low vitamin-D season, January or February, most ICUs hit capacity every year.

Google doesn't run its data centers at 5% capacity for the same reasons ICUs don't.

Re:Omicron variant more resistant to vaccine but causes less... by greedo on Tuesday December 14, 2021 @12:02PM (#29554035)
Sure. It's normal for hospitals to be delaying routine surgical procedures (where they make most of their money) due to not enough staff and beds. It's not just about ICU capacity, it's the overall hospital capacity. My small town has three primary hospitals, and all are seriously overloaded now.
Re:Omicron variant more resistant to vaccine but causes less... by SippinLean on Tuesday December 14, 2021 @11:01AM (#29553028)
> For individuals who have had COVID-19 previously, the risk of reinfection with Omicron is significantly higher, relative to prior variants.

https://www.discovery.co.za/corporate/news-room

Re:Omicron variant more resistant to vaccine but causes less... by gjm11 on Tuesday December 14, 2021 @11:07AM (#29553107)
Doesn't e.g. "a 73% relative risk of reinfection" mean being 0.73x as likely to be infected?

These numbers show (as one would expect) that prior infection makes you less likely to get Omicron, and that prior infection with more recent strains does so more effectively. (Which might be because they're more Omicron-like, or because the infection was more recent. I'm guessing more the latter.)