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Re:Brains on Drugs: How tinkering with consciousness became ... by UweSchmidt on Thursday June 22, 2023 @03:23AM (#36429004)
It seems there are plenty of unsuccessful "consciousness-tinkerers" out there:

- friends and people you've met who fell off the radar, some came back and now speak negatively about their past drug use - plenty of homeless drug users in big city streets, clearly in a bad state of mind - dead celebrities, their path documented by the media

So I have a hard time understanding how these articles downplay the risks and downsides, why they even pop up on HN and are so well received. On Fentanyl the straw man is "carpet bombing Mexico", the only alternative cheaper and more dangerous versions of this drug? That sounds a little tone-deaf.

It's one thing if you are well-established in life and experiment with a mushrooms from a trusted source under expert guidance - may you become a better fin-de-siècle poet. But opening the floodgates to the general public even more? Can't be good.

Re:Brains on Drugs: How tinkering with consciousness became ... by pantalaimon on Thursday June 22, 2023 @04:43AM (#36429513)
Opioids are the most dangerous as they go straight to satisfy your deepest desires like nothing else, anyone can fall for them.

I feel it takes a certain kind of person to get hooked on stimulants, I just find them rather boring.

Those are also drugs that can be rather subtle, so it’s possible to integrate them into daily life which makes starting an African easy.

Psychedelics on the other hand are much too intense of an experience to take casually, those truly let you tinker with consciousness. Most people will take them a couple of times a year at most and are fine.

Re:Brains on Drugs: How tinkering with consciousness became ... by danielbln on Thursday June 22, 2023 @08:08AM (#36430889)
Psychdelics are only intense and borderline overwhelming with a high dose, at low/micro doses they have a very different effect/expression. That's why microdosing is a thing, and why the term "museum dose" exists.
Re:Brains on Drugs: How tinkering with consciousness became ... by spoiler on Thursday June 22, 2023 @08:15AM (#36430961)
There's some research that shows that microdosing psilocybin isn't nearly (or at all) as effective as taking a regular dose. "Heroic" doses seem most promising from the neurological/neuroplasticity aspect, but yeah they can be... Quite something (even when you take care of S&S).
Re:Brains on Drugs: How tinkering with consciousness became ... by grugagag on Thursday June 22, 2023 @08:23AM (#36431039)
Never heard of the museum dose term. Can you share your experience?
Re:Brains on Drugs: How tinkering with consciousness became ... by morog on Thursday June 22, 2023 @09:13AM (#36431653)
Museum dose is somewhere between art gallery dose and planetarium dose. Under forest explorer dose and way under isolated beach dose.
Re:Brains on Drugs: How tinkering with consciousness became ... by danielbln on Thursday June 22, 2023 @10:11AM (#36432453)
At least in the LSD world it is said that 10mcg is a microdose, 20-50mcg is a museum dose (meaning, you can appreciate and navigate a museum while being acutely affected by the effects of the psychedelic, but not to a degree that it's overwhelming/debilitating. Anything north of 100mcg is a "proper" recreational dose, and a heroic dose I believe is anything from 300mcg upwards (very dependant on person, experience, tolerance).
Re:Brains on Drugs: How tinkering with consciousness became ... by FeteCommuniste on Thursday June 22, 2023 @01:30PM (#36435708)
What does "starting an African" mean?
Re:Brains on Drugs: How tinkering with consciousness became ... by pantalaimon on Tuesday July 04, 2023 @04:26PM (#36592098)
It should mean "starting an addiction" but auto-correct decided otherwise :/
Re:Brains on Drugs: How tinkering with consciousness became ... by explorer83 on Thursday June 22, 2023 @04:45AM (#36429519)
The short term effects of many drugs seem harmless. Because they seem harmless, it makes the anti-drug messaging seem overblown. It's usually too late once the long term effects are noticed. I wish there was a better way to get that message through other than experience.
Re:Brains on Drugs: How tinkering with consciousness became ... by grugagag on Thursday June 22, 2023 @08:20AM (#36431006)
Moderation is key. But there’s a scale to moderation that has to be learned as well.
Re:Brains on Drugs: How tinkering with consciousness became ... by cmh89 on Thursday June 22, 2023 @10:23AM (#36432632)
>I wish there was a better way to get that message through other than experience.

There is, puritanical American culture just wont do it. Abstinence only education, whether for sex or drug consumption doesn't work.

It's completely viable to talk to kids about risk factors for different drugs. When I was growing up they acted like marijuana and heroin were the same risk factors.

'Drugs are fun until they aren't' is something kids can understand. We should also talk about how people are different and some people can do recreational drugs and never have a problem and others can do the same amounts of drugs at first and develop an addiction.

Re:Brains on Drugs: How tinkering with consciousness became ... by jonhohle on Thursday June 22, 2023 @10:46AM (#36432956)
Except abstinence education is shown to delay sexual activity [0] (and possibly drug activity). Normalizing potentially dangerous behavior under the assumption that it can be safer is not a replacement for saying you probably shouldn’t do it until you’re able to understand and handle the consequences.

0 - https://jamanetwork.com/journals/jamapediatrics/fullarticle/...

Re:Brains on Drugs: How tinkering with consciousness became ... by cmh89 on Thursday June 22, 2023 @12:40PM (#36434848)
Basing anything on one social experiment is not wise.

“The weight of scientific evidence shows these programs do not help young people delay initiation of sexual intercourse,” says co-author John Santelli, professor of Population and Family Health at the Mailman School. “While abstinence is theoretically effective, in actual practice, intentions to abstain from sexual activity often fail. These programs simply do not prepare young people to avoid unwanted pregnancies or sexually transmitted diseases.” [0][1]

Further, abstinence only sex education is positively correlated with teenage pregnancy rates

"After accounting for other factors, the national data show that the incidence of teenage pregnancies and births remain positively correlated with the degree of abstinence education across states: The more strongly abstinence is emphasized in state laws and policies, the higher the average teenage pregnancy and birth rate. "[2]

Informing youth about the realistic outcomes of actions, whether its sex or taking drugs, is going to be a lot more effective than just telling them not to do it.

[0]https://www.publichealth.columbia.edu/news/abstinence-only-e... [1]https://www.jahonline.org/article/S1054-139X(17)30297-5/full... [2]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194801/

Re:Brains on Drugs: How tinkering with consciousness became ... by vorpalhex on Thursday June 22, 2023 @11:22AM (#36433545)
> Abstinence only education, whether for sex or drug consumption doesn't work.

This line gets repeated a lot, with the implied assumption that since X doesn't work the solution must be to invert X.

That's incorrect.

You know how you dramatically reduce teen pregnancy? You increase their socio-economic status.

The fix to drug use is not to teach kids the best way to shoot heroin or how to drug test for fentanyl, anymore than the fix for teen pregnancy is practicing putting condoms on bananas.

Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @12:09PM (#36434354)
Except "putting condoms on bananas", which is a hilariously bad faith description of sex ed, has demonstrably reduced teen pregnancy.
Re:Brains on Drugs: How tinkering with consciousness became ... by vorpalhex on Thursday June 22, 2023 @04:32PM (#36438529)
That was my non-abstinence sex ed experience as a University freshman. I mean there was a certain amount of reading and the usual dumb multiple choice quizzes too, but it was not a medical course.

(We actually had a wooden practice phallus, but the banana line was funnier.)

Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @05:27PM (#36439269)
Your only sex ed was in University? That's unusual. We didn't have sex ed in university, we had "health class" all throughout middle and part of high school. It covered lots more than birth control methods too, like what signs there are you are in an emotionally abusive relationship.
Re:Brains on Drugs: How tinkering with consciousness became ... by cmh89 on Thursday June 22, 2023 @12:40PM (#36434871)
>That's incorrect.

You're welcome to find some sources that support your assertion. All the research on the matter disagrees with you though.

Re:Brains on Drugs: How tinkering with consciousness became ... by randomopining on Thursday June 22, 2023 @11:02AM (#36433193)
Which ones do you think this applies to? Long term effects
Re:Brains on Drugs: How tinkering with consciousness became ... by dweymouth on Thursday June 22, 2023 @05:53PM (#36439594)
Ironically, the two main legal drugs (excluding caffeine) - tobacco and alcohol - have some of the worst long term effects. Others can have long term effects though, like MDMA is somewhat neurotoxic but not to a degree that matters with infrequent acute use, but it becomes very relevant if someone were to use it regularly.
Re:Brains on Drugs: How tinkering with consciousness became ... by YetAnotherNick on Thursday June 22, 2023 @04:58AM (#36429599)
> But opening the floodgates to the general public even more? Can't be good.

At least historically it hasn't been true[1][2]. In fact I had used nicotine gums which are easily available as OTC drug in the past to help cure my smoking addiction.

Obviously I think there are certain kind of junkies who would exploit legalization and do significantly more harm to themselves than good, but they are likely doing it now anyways. Most drug users I know of do consciously care about addiction potential.

[1]: https://www.colorado.edu/today/2023/01/24/gateway-drug-no-mo...

[2]: https://www.theguardian.com/news/2017/dec/05/portugals-radic...

Re:Brains on Drugs: How tinkering with consciousness became ... by thr_msc on Thursday June 22, 2023 @06:48AM (#36430233)
Ironically enough this is exactly what the tone for drugs was in the early mid sixties. Then the summer of love happened and people couldn't ignore tweens whoring themselves out for smack because they expanded their consciousness first.

Look at the size of the average American. They can't handle cheese responsibly. But we're supposed to think that now they'll manage acid?

Re:Brains on Drugs: How tinkering with consciousness became ... by silveraxe93 on Thursday June 22, 2023 @07:11AM (#36430382)
Have you ever done acid? If you want to reduce drug use, you should legalise LSD and make it easy to buy.

Your average American that "can't handle cheese responsibly" will try it once, have a terrible 12h and swear off drugs for life. With no long term health effects from one dose.

Re:Brains on Drugs: How tinkering with consciousness became ... by rocketbop on Thursday June 22, 2023 @07:42AM (#36430620)
Yea for sure. Mushrooms and LSD are not really popular and not drugs drug addicts gravitate towards.

I don’t thin legalisation would hugely increase use.

Re:Brains on Drugs: How tinkering with consciousness became ... by spoiler on Thursday June 22, 2023 @08:12AM (#36430929)
Not to mention that due to tolerance build up, you can't take LSD/psilocybin too often. And also, they don't "make you" wanna take them often either.

This might be anecdotal, but even though they can be fun, but they're also very exhausting and make you introspective and also kinda encourage you to think about improving different aspec of your life. Sure, there's some bad trips that make people psychotic, but I think that legalisation and regulations would help protect those peope, rather than harm them, because there's usually an underlying condition that triggers such an episode. On the flip side, I've had bad trips a few times and they usually taught me a lot about myself, the people around me, and how I lived life at the, which in turn pushed me to change for the better, and improve some aspects of my life.

Re:Brains on Drugs: How tinkering with consciousness became ... by bryanrasmussen on Thursday June 22, 2023 @08:29AM (#36431112)
>Not to mention that due to tolerance build up, you can't take LSD/psilocybin too often. And also, they don't "make you" wanna take them often either.

these arguments never seem to have a separate addictive from non-addictive drugs component.

Re:Brains on Drugs: How tinkering with consciousness became ... by sowbug on Thursday June 22, 2023 @11:08AM (#36433306)
Not that I have any data to back up this anecdote, but you don't see people in rehab for tryptamines. But you do for alcohol, coke, heroin, and meth.
Re:Brains on Drugs: How tinkering with consciousness became ... by BasedAnon on Thursday June 22, 2023 @07:39AM (#36430592)
>Your average American that "can't handle cheese responsibly" will try it once, have a terrible 12h and swear off drugs for life

You severely underestimate how much most people want to escape their lives, even if the experience is negative. It's silly to act like people don't self-harm.

Re:Brains on Drugs: How tinkering with consciousness became ... by silveraxe93 on Thursday June 22, 2023 @08:43AM (#36431274)
If they want to escape their lives they'll just become an alcoholic.

I'm not denying that people will self-harm. But the argument that people will self-harm with LSD needs to ignore that there's plenty of better drugs legalised already

Re:Brains on Drugs: How tinkering with consciousness became ... by BasedAnon on Thursday June 22, 2023 @10:28AM (#36432683)
Alcohol is much worse than LSD
Re:Brains on Drugs: How tinkering with consciousness became ... by soligern on Thursday June 22, 2023 @11:34AM (#36433759)
In a way. It has much worse physical outcomes over the long term especially if you’re drinking humongous amounts. However, alcohol/nicotine etc. don’t change your modality of thought processes or your underlying perspectives on life. Anecdotally from that perspective LSD is way, way more destructive. It can reconstruct you as a shell of the person you were, and very quickly. I’ve seen it happen so many times and anyone arguing the alcohol is worse than LSD is missing the forest for the tree.
Re:Brains on Drugs: How tinkering with consciousness became ... by skyyler on Thursday June 22, 2023 @12:37PM (#36434797)
>However, alcohol/nicotine etc. don’t change your modality of thought processes or your underlying perspectives on life.

Go to a couple of AA meetings and say that again.

Re:Brains on Drugs: How tinkering with consciousness became ... by pixl97 on Thursday June 22, 2023 @10:56AM (#36433108)
>You severely underestimate how much most people want to escape their lives

Hey, lets optimize society for human happiness and enjoyment without escapism then...

Moloch: "Now just hold the fuck up, I have some corporations to run"

Re:Brains on Drugs: How tinkering with consciousness became ... by Communitivity on Thursday June 22, 2023 @08:38AM (#36431214)
"no long term health effects from one dose" does not account for the possibility of persistent flashbacks, or for bad trips that can cause lasting psychological trauma.

LSD bonds with something in the brain, such that it causes persistent flashbacks more than any other hallucinogen, sometimes years later. Taking it just once to try it might not have any effect, or might cause flashbacks for the rest of your life. Depends on your personal neurochemistry, the dosage, form of dosing, and your mental state. A friend who had taken LSD described it to me once something like this: LSD sometimes takes any cracks (neurosis or psychosis) in your mind and expands them wide open, forcing you to look into them. If you're aware of them already and they're minor, it can be helpful, sometimes expanding your mind to new capabilities. If you've been unaware or worse, in denial, or they're major, then you get a bad trip that may come back to haunt you over and over again over the years.

Flashbacks that continue to occur after the original drug effects have worn off are a medically recognized phenomenon, which is documented in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) as hallucinogen persisting perception disorder.

Flashbacks typically happen in the days or weeks following ingestion of the drug but can happen months or even years after the drug use has been discontinued.

Re:Brains on Drugs: How tinkering with consciousness became ... by silveraxe93 on Thursday June 22, 2023 @08:53AM (#36431387)
Eh... fine. People won't come out unscathed in literally all cases.

However the risk from one dose is minimal. If your risk threshold is so close to 0 then we should be banning way more things today.

Re:Brains on Drugs: How tinkering with consciousness became ... by scrozart on Thursday June 22, 2023 @10:30AM (#36432727)
I've done LSD numerous times, including "heroic" doses, as have many of my friends, starting 30 years ago (I haven't in a while as i no longer feel the need to blow open those doors).

Not one of us has ever had a single flashback, let alone "persistent" flashbacks. If they were ever really an issue, it was long ago with different/absurdly strong formulations.

Re:Brains on Drugs: How tinkering with consciousness became ... by GuB-42 on Thursday June 22, 2023 @12:42PM (#36434902)
I don't believe in the "LSD binds to something in the brain and this causes flashbacks". LSD obviously binds to something in the brain during the trip, like all psychoactive substances, but after that, it is gone. LSD degrades relatively easily, you only get micrograms of it and there are known metabolic pathways.

A more convincing theory for flashbacks is that they are similar to PTSD. LSD can give really intense and memorable experiences, and in the case of a bad trip, they can be considered traumatic. Symptoms show similarities too. Essentially, flashbacks are just memories, good or bad, and in the worst cases, so bad as to haunt you for years.

Hallucinogen Persisting Perception Disorder (HPPD) is not like flashbacks. As the name suggests, it affects perception, i.e. senses, commonly in the form of visual noise, distinct from what is experienced during a trip. Think something like tinnitus. We know it exists, but the details are unclear.

Re:Brains on Drugs: How tinkering with consciousness became ... by PaulHoule on Thursday June 22, 2023 @09:49AM (#36432140)
The Netherlands has struggled to commercialize a safe psychedelic.

LSD is not so dangerous per se if you are in good hands. It does leave you discombobulated for 12 hours or so and put somebody into a strange and sketchy city like Amsterdam and some of them will get into trouble. Mushrooms are a little better because the duration is shorter but they still didn't find the problems acceptable. They tried the stimulating and hallucinatory 2C-T2 which is somehow entirely non-cosmic but I think even that failed market testing.

After all these years a pastor I know is providing psilocybin therapy for the terminally ill which they are doing in a tightly controlled

https://en.wikipedia.org/wiki/Ganzfeld_effect

environment and of course accompanying people for the whole tip.

Re:Brains on Drugs: How tinkering with consciousness became ... by cmh89 on Thursday June 22, 2023 @10:38AM (#36432825)
Amsterdam already has a problem with alcohol getting people in trouble. Millions of people take mushrooms every year with no issues.

The problem is we have such a high bar for pyschedelics that isn't applied to other recreational drugs.

Re:Brains on Drugs: How tinkering with consciousness became ... by totallywrong on Thursday June 22, 2023 @12:36PM (#36434753)
> put somebody into a strange and sketchy city like Amsterdam and some of them will get into trouble

Funny you say that because I couldn't have wished for a better trip than roaming Amsterdam with my friends when I tried mushrooms all those years ago. The canals, the architecture.. it was a fairy tale and I remember it dearly.

Re:Brains on Drugs: How tinkering with consciousness became ... by PaulHoule on Thursday June 22, 2023 @02:27PM (#36436593)
I remember getting bitched out for wandering around stoned in Het Vondelpark.
Re:Brains on Drugs: How tinkering with consciousness became ... by andelink on Saturday June 24, 2023 @04:36AM (#36456750)
Was just about to say this. My shrooms trip in Amsterdam was nothing short of magical. Such a colorful, vibrant city. It was beautiful
Re:Brains on Drugs: How tinkering with consciousness became ... by scruple on Thursday June 22, 2023 @11:26AM (#36433622)
> Have you ever done acid?

Yes, and a variety of other psychedelics in my early 20s. I remember spending time on erowid and then seeking out substances. Mescaline, peyote, ketamine, psylicobin, acid, GHB, DXM, others I'm forgetting.

I wish I had never done any of it.

Re:Brains on Drugs: How tinkering with consciousness became ... by novelwere on Friday June 23, 2023 @01:36AM (#36443203)
Can i ask why?
Re:Brains on Drugs: How tinkering with consciousness became ... by scruple on Friday June 23, 2023 @10:30AM (#36447293)
I had a few bad trips, one being very bad and which changed the direction of my life. It also made me realize that I was doing these things for the wrong reasons (mostly peer pressure, or a desire to fit in with certain crowds, etc.). In retrospect, it just wasn't very fun, and certainly wasn't a useful way (for me) to live my life.
Re:Brains on Drugs: How tinkering with consciousness became ... by davidguetta on Thursday June 22, 2023 @08:10AM (#36430908)
Best comment ever. And also true. I do drugs what i feels is responsable (5 times a year) and i always feel im the only one doing it responsibly among people i know who do drugs.
Re:Brains on Drugs: How tinkering with consciousness became ... by randomNumber7 on Thursday June 22, 2023 @01:19PM (#36435533)
> I do drugs what i feels is responsable (5 times a year)

One problem is that you can't get honest information about what is responsable, besides the "all drugs are evil" propaganda. Like you can defenitley smoke weed more often and call it responsable, but for MDMA 5 times is already quite at the edge imo. And people don't realize that easily.

Re:Brains on Drugs: How tinkering with consciousness became ... by davidguetta on Thursday June 22, 2023 @08:50PM (#36441309)
> for MDMA 5 times is already quite at the edge imo

Indeed, but I was speaking of 5 times like 1 LSD 1 mushroom, 1 coke and 1 mdma a year or something, with extremely cautious dosing..

> you can't get honest information about what is responsable

This is really debatable or even not true. There are several website (erowid, r/drugs) with literally thousands of not tens of thousands of reports and experiences of various people, including thoughts on multi-year / multi-decade drug experiences. If you sincerely look for the information there's everything you need

Re:Brains on Drugs: How tinkering with consciousness became ... by scotty79 on Thursday June 22, 2023 @08:36AM (#36431199)
"I handle cheese responsibly" is a great thing to put on a t-shirt.
Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @12:13PM (#36434409)
But then I'd be a liar
Re:Brains on Drugs: How tinkering with consciousness became ... by SamPatt on Thursday June 22, 2023 @08:37AM (#36431213)
We aren't all average Americans.

Individual responsibility should apply here. I don't want my rights restricted because other people are fools.

If it's considered acceptable to tell people what they can and cannot put into their bodies because "average" people can't handle it, there's no limiting principle in place to stop our bodies from being controlled by others.

Re:Brains on Drugs: How tinkering with consciousness became ... by circlefavshape on Thursday June 22, 2023 @09:05AM (#36431534)
It actually is considered acceptable to tell people what they can and cannot put into their bodies. Legal restrictions on medicines and intoxicants are in place all over the world, and that hasn't led to "others" taking control of my body.
Re:Brains on Drugs: How tinkering with consciousness became ... by SamPatt on Thursday June 22, 2023 @09:55AM (#36432222)
>Legal restrictions on medicines and intoxicants are in place all over the world, and that hasn't led to "others" taking control of my body.

If you say so. I believe prohibition exerts substantial control over our bodies, and also corrodes other aspects of personal freedom (such as the Fourth Amendment in the US).

Re:Brains on Drugs: How tinkering with consciousness became ... by MichaelZuo on Thursday June 22, 2023 @11:37AM (#36433806)
Well if you don't believe in any medicine prohibitions, then you'd be arguing against literally every government in the world (except maybe Somalia) plus the UN and hundreds of other IGOs, NGOs, etc...
Re:Brains on Drugs: How tinkering with consciousness became ... by Mordisquitos on Thursday June 22, 2023 @12:43PM (#36434916)
Spain for instance does not impose any legal restriction as to what you knowingly choose to put into your own body.

Not only is possession of any drug for personal use without an intent to distribute not a criminal offence in Spain, neither is consuming said drugs in the privacy of your own home. There is also no legal restriction on growing cannabis or psychedelic mushrooms on private property outside of public view, as long as the amounts are small enough that there is no reason to suspect an intent to distribute it.

Re:Brains on Drugs: How tinkering with consciousness became ... by randomNumber7 on Thursday June 22, 2023 @01:06PM (#36435343)
> then you'd be arguing against literally every government in the world

I'd like to do that^^.

1. Imagine what would happen to the mafia etc... No more war in mexico for example.

2. Normal people wouldn't just start taking heroine for example

3. Imagine what happens to jails

4. You could use some of the new tax money (which goes to the mafia currently) to hire some medical professionals. That way you could help the really addicted.

5. 100% pure heroin would not destroy the body (it was developed as painkiller). Those junkies are that f*ed up because of the other stuff they pump in their veins. How is that a win for society?

Re:Brains on Drugs: How tinkering with consciousness became ... by SamPatt on Thursday June 22, 2023 @01:55PM (#36436108)
Yes I believe every government in the world has made a mistake by implementing prohibition.

I also believe they were all in error when slavery was legal everywhere.

This is a combination of appeal to authority and appeal to majority.

Re:Brains on Drugs: How tinkering with consciousness became ... by MichaelZuo on Thursday June 22, 2023 @09:30PM (#36441680)
Why would anyone take you seriously? (Anymore so then the fringe groups that call for disbanding the UN, all central banks, etc...)
Re:Brains on Drugs: How tinkering with consciousness became ... by SamPatt on Friday June 23, 2023 @12:37AM (#36442824)
Ideas should be judged on their merit, not their popularity.

I don't care if my views are fringe and others choose to not take them seriously as a result. That's outside my control.

People accepting beliefs uncritically is the problem, and that applies equally to nutjob conspiracy theorists as well as people who accept the whatever the current groupthink believes.

A cursory examination of history is all that's needed to know that, at any given point in time, there are many beliefs across society which are just flat out wrong. To think that in 2023 somehow we've finally got it figured out is arrogance.

Re:Brains on Drugs: How tinkering with consciousness became ... by MichaelZuo on Friday June 23, 2023 @08:05AM (#36445700)
> Ideas should be judged on their merit, not their popularity.

No, ideas that need to be applied broadly should be judged on a combination of their merits and demerits, and popularity, as there are enforcement and political costs associated with any proposal (as long as the government needs to do make any changes whatsoever).

It would be different if it was a private proposal that will only affect you and immediate family.

To be entirely honest, it seems like you need to rethink this more thoroughly instead of just repeating memorable slogans.

Re:Brains on Drugs: How tinkering with consciousness became ... by misja111 on Thursday June 22, 2023 @10:13AM (#36432474)
I see what you mean and on the one hand I agree.

On the other hand, what to do if some people don't act responsibly and get addicted; and then for instance ruin their health or neglect their children. Who should be responsible for helping them go to rehab, fixing their health problems or helping their children? If it means the society has to take care of this, then isn't it also fair that society tries to prevent people from getting addicted in the first place? And prohibiting drugs is one way of trying to do that.

Re:Brains on Drugs: How tinkering with consciousness became ... by di456 on Thursday June 22, 2023 @11:16AM (#36433436)
> And prohibiting drugs is one way of trying to do that.

The war on drugs had tried and failed for decades. All it's done is enrich the cartels, fill prisons with minorities, create an oxycodone epidemic, flood the streets with cheap and deadly fentanyl, and countless other problems.

While the same government "protecting" citizens from harm is corrupt the point of the CIA becomeing drug traffickers on the side [1], making the problem even worse like throwing petrol on a fire.

[1] https://www.ojp.gov/ncjrs/virtual-library/abstracts/big-whit...

Prohibition has nothing to do with prevention.

Re:Brains on Drugs: How tinkering with consciousness became ... by SamPatt on Thursday June 22, 2023 @02:08PM (#36436301)
Prohibiting drugs is one way of trying to do that.

Has it succeeded? No.

Criminalizing it often makes it even more difficult to deal with the societal damage of addiction. Dealing with an addict is difficult, but dealing with an addict who is now a criminal is that much harder.

Society has all sorts of tools to help people who are struggling. Our criminal justice system is one of the least effective.

An addict is harming their family whether drugs are legal or not, and it's obvious from our current situation that their legal status doesn't prevent people from using drugs.

Re:Brains on Drugs: How tinkering with consciousness became ... by seanmcdirmid on Thursday June 22, 2023 @02:13PM (#36436376)
Not even Western Europe, especially Western Europe, has tried "decriminalizing drugs" yet. They might offer treatment as an alternative to incarceration for users, but they definitely don't allow police to ignore the problem (like we seem to do here in Seattle).

An addict who is now a criminal can be forced into treatment at least. An addict who can freely buy their drugs (because we aren't prosecuting dealers either) and do them on the street anywhere will just die faster (especially with fentanyl).

Re:Brains on Drugs: How tinkering with consciousness became ... by leetcrew on Friday June 23, 2023 @06:08PM (#36452826)
putting people in jail for doing drugs doesn't do much for their children or their health either.

I also don't see why it has to be all one way or the other. I agree that people with dependent children have no business taking risks with drugs. like you say, this creates a mess other people are compelled to clean up.

but what if a person doesn't have children (or successfully raised them to be independent adults)? as long as they pay whatever taxes they owe, why care what they do with their time?

Re:Brains on Drugs: How tinkering with consciousness became ... by pixl97 on Thursday June 22, 2023 @11:07AM (#36433297)
This is messy...

Lets imagine a hypothetical drug so we don't have to argue about the effects of real ones. This drug removes the idea of responsibility from your mind when your on it. This drug creates a paradox in your framework. You dictate that individuals have ultimate responsibility. This drug removes any internal idea of responsibility as a concept leading to bizzare and potential dangerous actions from the user.

Would you agree this drug should be banned then?

Re:Brains on Drugs: How tinkering with consciousness became ... by amanaplanacanal on Thursday June 22, 2023 @11:34AM (#36433750)
You’re talking about ethanol aren’t you.
Re:Brains on Drugs: How tinkering with consciousness became ... by pixl97 on Thursday June 22, 2023 @11:46AM (#36433988)
Nope. Was talking about something hypothetical with a 100% responsibility removal rate.

But with ethanol we tried that once, didn't work out well as you tend to create a police state to prevent it as it's easy to make.

Re:Brains on Drugs: How tinkering with consciousness became ... by SamPatt on Thursday June 22, 2023 @02:19PM (#36436481)
No, it should not be banned. The drug itself isn't the issue. If a person took precautions to ensure they couldn't harm others while using the drug (consenting trip sitter who can physically handle them, proper set and setting) then they should be able to do that.

However they must also bear the cost of any harm done in that state. The problem isn't that someone took a drug, it's that they did X thing to hurt others. Punish X thing, not the drug use.

I acknowledge that this has serious problems because not everyone acts responsibly. But the alternative is to implement a system which removes the basic freedom to control what goes into your own body... and still have people acting irresponsibly anyway.

Re:Brains on Drugs: How tinkering with consciousness became ... by refurb on Thursday June 22, 2023 @01:48PM (#36435984)
Not going to happen. People aren't even responsible enough to read their mortgage documents.
Re:Brains on Drugs: How tinkering with consciousness became ... by SamPatt on Thursday June 22, 2023 @01:57PM (#36436134)
Those people should bear the costs of acting irresponsibly.

The alternative is worse.

Re:Brains on Drugs: How tinkering with consciousness became ... by refurb on Thursday June 22, 2023 @08:05PM (#36440979)
We're already doing the opposite with most instances of personal responsibility.

I agree it's unfortunate.

Re:Brains on Drugs: How tinkering with consciousness became ... by thelastparadise on Thursday June 22, 2023 @10:08AM (#36432412)
The point of laws isn't to protect people from themselves.
Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @12:13PM (#36434404)
Ah yes, the government requires I wear a seatbelt because they think it's fun
Re:Brains on Drugs: How tinkering with consciousness became ... by scrozart on Thursday June 22, 2023 @10:32AM (#36432746)
Your comment indicates you can't differentiate between LSD and dangerous opioids. Cheese is the opioid supplying immediate gratification. LSD, and other hallucinogens, work much, much differently.
Re:Brains on Drugs: How tinkering with consciousness became ... by reddit_refugee3 on Thursday June 22, 2023 @08:03AM (#36430833)
Many (not all) of those things were results of the criminalization of drugs, as well as our refusal to take care of people with mental health issues.

Most overdoses could be avoided by knowing exactly what you're taking, at what dose, and maybe even under supervision (like at safe injection sites; places that have gone years without a single person dying on premises).

The homeless people thing is a failure of our healthcare and housing systems.

Fentanyl only exists on the black market because drugs are illegal. Fentanyl is kind of a shit high compared to other opioids, it's only a problem because dealers are cutting their illegal drugs with it.

Re:Brains on Drugs: How tinkering with consciousness became ... by DrThunder on Thursday June 22, 2023 @09:14AM (#36431662)
Addiction is the root issue, not overdosing. It's not enough to just stop people from dying, you need to actually give them quality of life.

"The homeless people thing is a failure of our healthcare and housing systems."

This is the result of drug addiction not the cause.

"Many (not all) of those things were results of the criminalization of drugs"

Don't agree, alcohol is perfectly legal and one of highest percentage addictions there is. Opioids are a legal prescription and also out of control.

Re:Brains on Drugs: How tinkering with consciousness became ... by randomNumber7 on Thursday June 22, 2023 @09:33AM (#36431915)
Yes, but often the root issue of addiction is mental health issues (and not only the drug itself). There are many people who occasionaly take drugs without strong addiction.

It depends a bit on the drug to be fair. Like you cant "occasionaly" smoke cigarettes, either you are addicted or not. You can occasionaly drink a beer and not become an alcoholic.

The people who become alcoholics almost always have some personal problems / mental health issues as a trigger.

But the world wide drug policy doesnt make any sense, because even a "evil" and highly addictive drug like cocaine is actually less addicting than smoking.

Re:Brains on Drugs: How tinkering with consciousness became ... by stef25 on Thursday June 22, 2023 @11:09AM (#36433315)
> Like you cant "occasionaly" smoke cigarettes, either you are addicted or not.

I was an occasional smoker for 20+ years. Could go weeks without a cigarette. Or smoke a few daily when stressed at work. Or smoke an entire pack on a night out.

Recently went through some personal hell and now I'm on 10-15 cigs a day and find it hard to stop. Absolutely because of the recent stress and trauma.

It is without a doubt one of the most pointless drugs in existence.

Re:Brains on Drugs: How tinkering with consciousness became ... by randomNumber7 on Thursday June 22, 2023 @11:44AM (#36433943)
> I was an occasional smoker for 20+ years. Could go weeks without a cigarette.

I think you are a very rare minority then.

Quit smoking is painfull (went through it multiple times). For me it feels so much better since I finally got it.

And since then my behaviour regarding other drugs also got a lot better, because you dont have that "hunger" to take s.th. from smoking.

> It is without a doubt one of the most pointless drugs in existence.

It doesnt even make you high lol.

Re:Brains on Drugs: How tinkering with consciousness became ... by Ylpertnodi on Thursday June 22, 2023 @01:22PM (#36435581)
"Like you cant "occasionaly" smoke cigarettes" I know several endurance sportsmen (no ladies were met, that I knew about) who will smoke an occasional cigarette. As an ex-smoker (took up endurance sports), I was astonished when I saw super-fit people casually smoking.
Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @07:55PM (#36440902)
> It is without a doubt one of the most pointless drugs in existence.

I don't know about this one. Cigarettes specifically certainly have enough chronic downsides to outweigh their upsides for me, but nicotine in general serves as a pretty good, light dopamine hit, with relatively few acute downsides. You don't intoxicated, it doesn't take long to ingest, and it's available enough to not become life-consuming. It's not a coincidence that it's a very common habit.

I say this as someone who used to use cigarettes, but took up vaping nicotine instead when I realized it didn't make my clothes reek and scratched the same itch. Everybody has habits around dopamine management. Some people snack, some people spend too much time on social media, some people gamble (in casinos or in brokerages). Personally, I'm prone to snacking, and I eventually realized I could either smoke and be attractive, or snack and get fat. It was an easy enough choice.

Re:Brains on Drugs: How tinkering with consciousness became ... by DrThunder on Thursday June 22, 2023 @12:58PM (#36435208)
"Like you cant "occasionaly" smoke cigarettes, either you are addicted or not."

I don't think there's any factual evidence for this at all. I occasionally smoke cigars (like 1-2 times a year) and I'm not addicted to them. Multiple friends/family members do the same.

"Yes, but often the root issue of addiction is mental health issues (and not only the drug itself)."

Agree, but not everyone who has mental illness issues resorts to drugs for help so there are many other factors to consider.

Re:Brains on Drugs: How tinkering with consciousness became ... by di456 on Thursday June 22, 2023 @11:01AM (#36433191)
> Addiction is the root issue, not overdosing

What is the root of addiction? This is the best book on it.

https://drgabormate.com/book/in-the-realm-of-hungry-ghosts/

Re:Brains on Drugs: How tinkering with consciousness became ... by tiffanyg on Thursday June 22, 2023 @11:56AM (#36434159)
Ooh, unexpected and interesting reference to one of the "realms" of human experience (in the terminology / model of Buddhism, in particular, to me).

"Hungry ghosts" is exactly it (as I've learned / come to view the meaning), speaking from personal experience with drives at various times morphing into the ... unhealthy.

Humans have all sorts of axes - behaviorally, environmentally, genetically. It's interesting to look at these, and look at how traits complement and contrast ... how subtle tweaks and changes in parameters can be the difference between, say, a high-performing researcher with a solid career, and a ... someone who falls off the map to greater or lesser degrees [1].

One thing I am quite familiar with, these days, is: the very traits that set people up for "(very) high performance", also set people up for addictions and other issues. AA and other related groups are quite enriched in, in my experience, high performers (as well as very interesting / idiosyncratic / "exceptional" people*) of various types. The tendency to get sucked into things ... to become obsessive, to push boundaries, "openness to experience", etc. easily contribute to someone becoming a "star" and/or a "strung-out junkie".

The Buddhist, AA (rooted in "Oxford Group" / "early Christian" ideas), etc. ideas about "spirit" and a sort of "middle way" and all of that, provide practical guidance (and practices) that can really help balance out the serious negatives that can come out of some traits / mixtures of traits.

I'll look into this book further when I have a moment. Thanks for pointing it out!

[1] https://en.wikipedia.org/wiki/John_Forbes_Nash_Jr. - not necessarily the best example, here, but, apt enough and what comes to mind this moment ... representing, to some extent, disparate outcomes in one individual (take that, dualism!)

* Note: none of this should be taken as any kind of "value judgment" - specifically, 'positive' or 'negative' ... these terms can be quite positive or negative, as reflected in almost anyone I've met, as well as myself

Re:Brains on Drugs: How tinkering with consciousness became ... by di456 on Thursday June 22, 2023 @02:10PM (#36436327)
The tl;dr is that a lot of addiction comes from unresolved trauma. Drugs, particularly opioids, give the sensation of returning to the mother's womb. They are comforting in the moment but it passes quickly and never quite get back to the satisfaction of that first high.
Re:Brains on Drugs: How tinkering with consciousness became ... by InCityDreams on Thursday June 22, 2023 @11:05AM (#36433250)
>"The homeless people thing is a failure of our healthcare and housing systems."

>This is the result of drug addiction not the cause.

Not always: lose job, lose house, get offered cheap accommodation, meet some people...seen it happen.

Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @12:07PM (#36434327)
Or, because of how things in cities are right now: Your rent increased but your pay didn't. Now you are homeless because it's impossible to pay rent with money you aren't getting. Now you have your job and car but no home, and are homeless, and now people want to treat you as lazy even though you work 60 hours a week for jobs you've been in for a decade.

Rent has gone up almost double in the city I live in (a small city you won't think of) and nobody's jobs decided to double their pay, so there's a lot of people who literally can't afford just to have a legal place to sleep.

Re:Brains on Drugs: How tinkering with consciousness became ... by giraffe_lady on Thursday June 22, 2023 @11:36AM (#36433784)
> This is the result of drug addiction not the cause.

Where'd you get that? Studies I've seen of homeless addicts show that a simple majority were not addicted when they became homeless. Certainly it's a common cause of homelessness but still only accounts for a minority.

Re:Brains on Drugs: How tinkering with consciousness became ... by DrThunder on Thursday June 22, 2023 @01:02PM (#36435269)
I don't agree at all. Most addicts on the streets were addicts beforehand and the reason they're homeless has a lot do with their addiction and being unable to maintain a working lifestyle.

It's DEFINITELY not a minority. They don't just randomly end up on the streets from some random cause and then turn into addicts. That rarely happens, there are too many opportunities in this country to just become completely homeless from bad luck.

Re:Brains on Drugs: How tinkering with consciousness became ... by giraffe_lady on Thursday June 22, 2023 @02:43PM (#36436842)
It’s not a matter of opinion though look it up.
Re:Brains on Drugs: How tinkering with consciousness became ... by DrThunder on Monday June 26, 2023 @10:03AM (#36479780)
There's no scientific basis for what you're saying, so it is in fact an opinion you're spouting off.

The only way to do a study on this would be to ask. They're not tracking people throughout their lives to see if they're suddenly becoming homeless and turning into drug addicts afterwards.

Use some critical thinking please. Just because some media outlet says it's so doesn't make it true.

Re:Brains on Drugs: How tinkering with consciousness became ... by ak_111 on Thursday June 22, 2023 @09:54AM (#36432212)
I think your argument is a bit shaky if you take into consideration alcohol in society.

alcohol consumption is perfectly acceptable, very well-regulated, “safe”, and alcoholics receive plenty of support and sympathy from public health, yet that doesn’t stop alcoholism ripping through society with countless victims (and victims of victims).

You can even make the argument that many alocholics wouldn’t be so if alcohol was less normalised in society

Re:Brains on Drugs: How tinkering with consciousness became ... by throwanem on Thursday June 22, 2023 @10:07AM (#36432394)
The argument has been made before. It didn't turn out all that well, not least because methanol is neurotoxic.
Re:Brains on Drugs: How tinkering with consciousness became ... by nuxi on Thursday June 22, 2023 @10:49AM (#36433002)
I think you meant "ethanol", methanol is fatal to drink even in small doses.
Re:Brains on Drugs: How tinkering with consciousness became ... by throwanem on Thursday June 22, 2023 @11:15AM (#36433429)
No, I meant methanol. It's an easy contaminant to produce through improper distillation practice, and the most common of several contaminants which produced unfortunate outcomes among drinkers of illegal liquor during prohibition.
Re:Brains on Drugs: How tinkering with consciousness became ... by nuxi on Thursday June 22, 2023 @11:54AM (#36434108)
Right, thanks, I missed your point.
Re:Brains on Drugs: How tinkering with consciousness became ... by htag on Thursday June 22, 2023 @12:03PM (#36434255)
Methanol specifically is produced during the distillation process. The methanol vapors and ethanol vapors reside next to each other in the distillation column, making it a common impurity that is brought over in the distillation process. Great care needs to be taken to avoid collecting the methanol.

This simple fact is the greatest argument for distillation having much higher legal barriers than the simple brewing involved in beer/wine/mead.

Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @12:33PM (#36434709)
Distilling doesn't produce jack-diddly-squat. It just concentrates. Methanol is a side effect of the fermentation process, and only common with exotic carbohydrates. In a normal beer, wine, or wash, you'll find less methanol than in your morning glass of orange juice.
Re:Brains on Drugs: How tinkering with consciousness became ... by throwanem on Thursday June 22, 2023 @04:08PM (#36438107)
I don't know what "exotic" means in the context of moonshine, but I've known some mountain men who weren't clever or careful about it and would ferment damn near anything - which is why I've drunk moonshine exactly once, and intend that to remain the case for the balance of my life.

Poking around the web, it seems as if making liquor at home has become popular among booze nerds. That's great and all, but I wouldn't call it moonshine, and I'd be very hesitant about how much I reasoned based on what well-informed people do today about the practices of a century ago, or indeed about the practices of today among those for whom making moonshine is more a family tradition than a hobby.

Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @06:02PM (#36439718)
If it vaguely, and I mean vaguely resembles starch or sugar, you're not getting methanol. It's substantially harder to convert long polysacharides into ethanol/methanol than it is to convert starches and simple sugars, to the point that the less informed a person is, in the off chance they succeeded in making alcohol, the less likely there's going to be substantial methanol levels.

The vast majority of moonshine stills were just churning out unaged corn whiskey from animal feed corn. There is no risk of methanol poisoning in that scenario.

Re:Brains on Drugs: How tinkering with consciousness became ... by dweymouth on Thursday June 22, 2023 @05:48PM (#36439542)
Speaking technically, methanol isn't produced during distillation, it's concentrated. Since it boils at a lower point than ethanol, it disproportionately comes out in the "heads" of a distillation run. The source wine/beer/mash already has all the methanol in it, it's just it's not a problem when present in the small quantities in a non-distilled drink, alongside with a much greater amount of ethanol. (Ethanol can actually act as an antidote to methanol since your body processes it first and can then excrete much of the methanol unmetabolized)
Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @12:30PM (#36434665)
The risk of methanol poisoning in moonshine is grossly overrated. Simply put, you have to do some stupid shit to end up with dangerous amounts of methanol. The methanol content in a beer, wine, or mash precursor to liquor production will be absolutely trivial, unless you are are doing something ridiculous like trying to make liquor from tree bark (the Greeks have a drink like this, it's heavily warned against in home distilling circles).

So why was methanol poisoning common during the Prohibition? Renatured fuel alcohol. To stop people from drinking fuel ethanol, the government poisoned the supply with methanol. People tried to come up with jerry-rigged solutions to remove the methanol, and more often than not failed. Some less scrupulous experimenters sold their results anyway, where it worked its way into the black market supply chain.

Re:Brains on Drugs: How tinkering with consciousness became ... by steppi on Thursday June 22, 2023 @11:10AM (#36433341)
Not that ethanol isn't also neurotoxic (to a much lesser degree), but bootleg moonshines common during prohibition often contained trace amounts of methanol, the number of people irreversibly injured by methanol poisoning greatly exceeded the number who died.

By 1926, according to Prohibition, by Edward Behr, 750 New Yorkers perished from such poisoning and hundreds of thousands more suffered irreversible injuries including blindness and paralysis. [0]

[0] https://content.time.com/time/specials/packages/article/0,28...

Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @11:53AM (#36434102)
Didn't the government also add methanol to non-consumption alcohol products as well, contributing to those poisoning numbers?
Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @12:37PM (#36434783)
This was likely the cause of the vast majority of methanol poisonings during the prohibition. You have to use exotic, hard to break down carbohydrates in your beer, wine, or mash (the pre-distillation fermented product), like tree bark, to end up with significant quantities of methanol.

Most of the methanol poisonings were from poorly "re"natured fuel alcohol.

Re:Brains on Drugs: How tinkering with consciousness became ... by steppi on Thursday June 22, 2023 @12:25PM (#36434585)
Yeah, industrial alcohols were (and still are) "denatured" with additives to make them toxic or unpalatable and industrial alcohol was often used as a precursor for bootleg spirits during prohibition. I think modern denaturants lean more towards unpalatable than toxic.
Re:Brains on Drugs: How tinkering with consciousness became ... by bittercynic on Thursday June 22, 2023 @11:07AM (#36433281)
I think GP was referring to the increase in methanol poisoning during prohibition.
Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @11:52AM (#36434086)
Prohibition reduced american alcohol consumption by about a third according to most estimates, and before it, americans were drinking insane amounts of hard liquor. Like the equivalent of multiple drinks a day.
Re:Brains on Drugs: How tinkering with consciousness became ... by pstuart on Thursday June 22, 2023 @01:32PM (#36435746)
It also promoted a lot of organized crime. Just like today (but worse, because now we have narco-states vs just gangs.

I lost a mother to alcohol and a brother to heroin. Both are technically quite safe when used appropriately and lethal when not. And they're going to be used regardless of legality, so let's make it safer for those that do as well as stop funding the cartels.

Re:Brains on Drugs: How tinkering with consciousness became ... by ak_111 on Thursday June 22, 2023 @01:35PM (#36435782)
I am sorry about your loss. However, if you want to talk technically, then the science over the last two decades has moved almost decisively to saying there is no safe level of alcohol consumption.
Re:Brains on Drugs: How tinkering with consciousness became ... by throwanem on Thursday June 22, 2023 @01:54PM (#36436083)
There's also no safe level of organized crime.
Re:Brains on Drugs: How tinkering with consciousness became ... by pstuart on Thursday June 22, 2023 @04:11PM (#36438153)
Yeah, alcohol is not healthy for people. But by safe I'm talking about a glass of wine with dinner or other low intake/healthy contexts.

But my point stands: people are going to do it regardless of the law, so let's stop criminalizing it. Being overweight is unhealthy too, should we arrest every fat person in the country "for their own good"?

Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @05:42PM (#36439465)
I'm not in favor of banning alcohol. I just want to dispel the false notion that prohibition didn't "work", when it empirically did.

We shouldn't ban alcohol because it's a hamfisted way to reduce alcoholism and harms from alcohol abuse. However, the 1910s didn't exactly have functioning rehabilitation programs.

Re:Brains on Drugs: How tinkering with consciousness became ... by pstuart on Friday June 23, 2023 @01:07PM (#36449611)
It might have worked if you squinted right. There was still plenty of alcohol for those of means.

Again, it came at a cost of organized crime. It was not a win.

Re:Brains on Drugs: How tinkering with consciousness became ... by LocalH on Saturday June 24, 2023 @10:45AM (#36459096)
We don't really have a functioning rehabilitation program now. The rates of failure and relapse are not exactly low. There are also often a bunch of hoops to jump through to even get access to them, most people are more interested in being "tough on crime" which really means "authoritarian".
Re:Brains on Drugs: How tinkering with consciousness became ... by goolz on Friday June 23, 2023 @08:01AM (#36445662)
Heroin, in a pure form, is non-toxic and as long as you don’t mix it with things and do too much you should be OK. Proper dosing is the huge part. But you could still easily die from slowing your heart down too much so I would not say “safe”. Non-toxic, let’s stick with that.
Re:Brains on Drugs: How tinkering with consciousness became ... by smoldesu on Thursday June 22, 2023 @10:12AM (#36432459)
> You can even make the argument that many alocholics wouldn’t be so if alcohol was less normalised in society

Didn't American and European prohibition vehemently disprove this theory?

Re:Brains on Drugs: How tinkering with consciousness became ... by runsWphotons on Thursday June 22, 2023 @10:37AM (#36432814)
Prohibition actually worked relatively well.
Re:Brains on Drugs: How tinkering with consciousness became ... by pixl97 on Thursday June 22, 2023 @10:54AM (#36433076)
It reduced harm until it started to increase harm.

At the end of the day human vice isn't going away.

Re:Brains on Drugs: How tinkering with consciousness became ... by skulk on Thursday June 22, 2023 @10:56AM (#36433117)
It's not useful to judge prohibition in a single dimension of "work well" to "didn't work". Sure, cirrhosis rates went down significantly but organized crime (a disease of its own) was gifted a torrent of money to fuel other activities.
Re:Brains on Drugs: How tinkering with consciousness became ... by joncrane on Thursday June 22, 2023 @11:28AM (#36433647)
It was a "loud minority" type of thing. The average person simply stopped drinking, which was fine.

In today's market, 10% of the drinkers consume 90% of the alcohol. So the efforts of the 10% and the people serving the 10%, and the efforts of law enforcement to stop them, resulted in many very high profile, violent events, which made it seem like it wasn't worth the effort.

Full disclosure, I'm an alcoholic in recovery and I'd be fine with alcohol being illegal. My main beef is that the laws are not internally consistent: THC is by far a milder drug than alcohol but alcohol is legal while THC is still mostly illegal in the US (federally).

Either legalize THC completely or ban alcohol if you want to be consistent.

Also worth noting, THC (at less than 0.3% which is plenty for gummies) and many very very close, but naturally occurring (in infinitesimal amounts) are technically legal federally and companies like 3CHI are exploiting those loopholes. You can buy a vape containing things like HHC, THC-P, THC-O, etc which is virtually indistinguishable from Delta-9 THC, so obviously the days of THC being illegal are numbered.

Re:Brains on Drugs: How tinkering with consciousness became ... by danenania on Thursday June 22, 2023 @11:56AM (#36434154)
But the people who are the problem drinkers still end up finding a source of alcohol. So now moderate drinkers have been prevented from having their drink or two, alcoholics are drinking just as much, but are more likely to be poisoned, and you’ve created a massive cash cow for organized crime. How is that anything but a total failure?
Re:Brains on Drugs: How tinkering with consciousness became ... by bfuller on Thursday June 22, 2023 @12:49PM (#36435043)
There are even better loopholes than that.
Re:Brains on Drugs: How tinkering with consciousness became ... by nosmokewhereiam on Thursday June 22, 2023 @01:19PM (#36435532)
If anyone can explain the THCA loophole, it'd explain how they are shipped directly to consumer.

It's the wild west but across the US. How is this possible, and will it be open until it's legalized federally?

"Why even get a license" is the incentive this creates.

Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @07:29PM (#36440685)
On the other hand, you can look at the vast majority of society that drinks in perfectly reasonable moderation. Teetotalers make up a tiny fraction of society, yet civilization hasn't crumbled to barbarism. If a community is experiencing alcoholism at such a rate that it's "ripping through society", then that suggests to me that there's a greater root evil than the bottle.
Re:Brains on Drugs: How tinkering with consciousness became ... by schrodinger on Thursday June 22, 2023 @09:19PM (#36441582)
Actually, you'd be surprised to learn that 20–40% of Americans don't drink. There are all different ways to define it leading to the ambiguous statistics (e.g. once a year, never, include/exclude under 21 year olds), but either way I found it very surprising how many people don't actually drink alcohol.
Re:Brains on Drugs: How tinkering with consciousness became ... by WastingMyTime89 on Friday June 23, 2023 @06:20AM (#36444934)
> “safe”

No idea of why you quote the word. Alcohol consumption is demonstrably unsafe. The estimate is that alcohol kills around 140 000 people per year in the USA. It's just legal because criminalisation was tried and proven to be not only useless but actually more harmful to society through its side effects, a situation similar to the one we are still having with all the other drugs which are still illegal basically.

Re:Brains on Drugs: How tinkering with consciousness became ... by jonhohle on Thursday June 22, 2023 @11:02AM (#36433195)
How are cities with a safe-injection sites doing at the moment? Over the last decade supporting drug use in transient (homeless) populations hasn’t had a positive effect on that population.

Legalization (or decriminalization) is a possible pathway to supporting people, but the current method of helping people with myriad issues stay in their current state in life (or worse, encourage more to enter it) is one of the biggest public health disasters facing urban areas. Major cities are being gutted by this failed line of thinking.

Re:Brains on Drugs: How tinkering with consciousness became ... by AlecSchueler on Thursday June 22, 2023 @11:24AM (#36433584)
Have you looked much at the situation in Portugal? I've only heard good reports about their efforts there.
Re:Brains on Drugs: How tinkering with consciousness became ... by jonhohle on Thursday June 22, 2023 @01:18PM (#36435524)
There are many places that are doing better than the US (which is 4ᵀᴴ from the bottom). Addressing affordable housing close to places of employment seems to be pretty helpful most places it’s tried. AFAICT, NIMBYism prevents that in most large cities (though why a tent city is preferable is beyond my understanding). I agree with decriminalization, but also that individuals should be able to function within a social framework. For those that can’t (not those who won’t), services should be provided to allow that person to thrive in the capacity that they can in the most minimally invasive way possible.
Re:Brains on Drugs: How tinkering with consciousness became ... by zeekaran on Thursday June 22, 2023 @01:55PM (#36436106)
> AFAICT, NIMBYism prevents that in most large cities (though why a tent city is preferable is beyond my understanding).

It's no different than "banning abortions to reduce the amount of abortions". It doesn't work that way in reality, and rather than face reality, they dig in deeper, stick fingers in their ears and go LALALALA CAN'T HEAR YOU. Except that NiMBYism goes strongly across both major political parties.

Though there's plenty to say about "affordable housing", many have argued we just need drastically more housing rather than a lot of government regulated housing prices. We're just not building enough in places people want to live, specifically because zoning (looping back to NiMBYism). [Andrew Price](https://andrewalexanderprice.com/blog20210125.php) and Strong Towns have plenty to say about this.

Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @12:00PM (#36434229)
Your understanding of the situation is pretty poor.

The reason cities are struggling with homeless populations isn't because "treat them like people with dignity" doesn't work, but rather that there are MOUNTAINS more homeless people than most cities fund helping. This is exacerbated by housing being stupidly more expensive than it has been in the past in cities. Homeless people don't have a home. Plenty of them have jobs they are desperately trying to keep. But when the average income in your city is less than the average housing cost, you inevitably get way more homeless people.

Also, the point of decriminalization of drugs is just to reduce unnecessary harm, since our justice system sees anyone in it as expendable and unwanted. If you want to actually help homeless people get off the street and back into society proper, you need to fund enough shelter beds for them, enough social workers such that they know these people by name and have the time to actually work for them, and some sort of jobs or education or enrichment programs.

Re:Brains on Drugs: How tinkering with consciousness became ... by jonhohle on Thursday June 22, 2023 @12:42PM (#36434893)
Cities with expanded funding for homeless populations are the ones with the issues. When I moved from Phoenix to Seattle in 2009 I was surprised by the level of homelessness there. The major difference: lots of support for urban homeless. I moved back and Phoenix has adopted many of the same concepts, and guess what? The homeless population is exploding here now as well.

I’m all for affordable housing and work programs and other things that allow those who have fallen on hard times ways to help themselves out. I’m also for psychiatric care for those who have mental health issues that won’t be able to help themselves. None of that involves safe spaces for recreational drug use. That only keeps people on their state or drags them down and provides incentive for others to follow (as evidenced by Seattle, Portland, SF, LA, etc.).

There are lots or organizations that will give people a place to stay, especially woman and children. The good ones will also have educational help and employment services as well. None of that needs to include trip sitters, needle exchanges, narcan, or paraphernalia vending machines.

Re:Brains on Drugs: How tinkering with consciousness became ... by driverdan on Thursday June 22, 2023 @01:13PM (#36435459)
> there are MOUNTAINS more homeless people than most cities fund helping

Last time I checked San Francisco spends something like $50,000 per year per homeless person. It's not a lack of funding in some places.

Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @05:37PM (#36439403)
San fransisco is up shit creek because even a cardboard box on the street fetches a $500 a month rent. The best option for them is probably a bus ticket to a much smaller city and a giant donation to that city's homeless funds, but what homeless person is going to take that offer when the other city might have a climate where you get to die from exposure?
Re:Brains on Drugs: How tinkering with consciousness became ... by derbOac on Thursday June 22, 2023 @08:12AM (#36430932)
So, I had a similar reaction. I'm about as libertarian as you can get with drug regulation, but found it odd that the article seemed to ignore the public health risk management arguments for drug regulation.

Still, we allow plenty of dangerous things to go unregulated, or far less regulated than drug use. Alcohol use is a glaring example, but you could go through a litany of things that US society legally allows that are very risky: guns, motorcycles, chainsaws, BASE jumping, various chemical cleaners and solvents, all kinds of sexual behavior, and so forth and so on.

Yes there are some that develop serious drug problems from use per se, but most do not, and those that do often (although not always) tend to be polyusers in the sense that if you look at their problems, it's often difficult to attribute it to a specific substance. So empirically there's a stretch to go from any use, to use of a specific substance, to such irreparable harm that it should be made illegal.

There's also many other mechanisms society has for regulating drug use, like revocation of rights due to incompetence in decision making (legally speaking), and so forth.

This isn't even getting into our hubris in uncertainty about potential benefits of substances, as manifested by changes in public discourse around psychedelics over the last century.

Seen from this perspective, the article might have a point about drugs being treated differently, as if by absence of discussion, the author is implicitly asserting that risk management is not actually the issue. But I still think the article would have been more effective by making that argument explicitly.

Then again maybe the author just thought public health risk management was a different, additional issue.

Re:Brains on Drugs: How tinkering with consciousness became ... by bryanrasmussen on Thursday June 22, 2023 @08:26AM (#36431077)
>It seems there are plenty of unsuccessful "consciousness-tinkerers" out there:

do you have some sort of stats in relation to successful ones?

Re:Brains on Drugs: How tinkering with consciousness became ... by yboris on Thursday June 22, 2023 @09:50AM (#36432150)
My favorite book on the subject: Legalize This!: The Case for Decriminalizing Drugs by Douglas Husak

The author argues that all drugs should be decriminalized. The TL;DR argument: going to jail is the worst thing the state does to a person so it needs to have an explanation of why. No rationalization can be given for the case of putting a person (user or "in possession of a drug") to jail.

https://www.versobooks.com/products/1795-legalize-this

This doesn't argue that doing drugs is a good idea, but we certainly, as a society, should not put people to jail (or even give fines for that matter).

Re:Brains on Drugs: How tinkering with consciousness became ... by amanaplanacanal on Thursday June 22, 2023 @11:38AM (#36433838)
I’m absolutely in favor of legalizing all recreational drugs, and selling them the same way we do liquor or tobacco to adults.

I also think that advertising any of them (including alcohol and tobacco) should be banned. Allow, but don’t encourage.

Re:Brains on Drugs: How tinkering with consciousness became ... by lazide on Thursday June 22, 2023 @10:41AM (#36432866)
For the same reason you’ll see articles talking about bar hopping, or glamorizing womanizing (less common now), or the latest celebrity shitshow, or travel to exotic locations.

People like escapism and excitement and feeling good in the moment.

People like to think they’re special and they’d never suffer the negative consequences.

And, truthfully - most of them do escape the negative consequences. Either by reading and not doing, or by doing and not being the problem cases, or by being lucky. How many/what proportion varies by the activity of course.

And so People click on it. And hence articles get read. And journalists write more articles, and the Overton window shifts.

Eventually, societal backlash occurs, or it becomes normal, or it gets boring and folks find something else novel to chase.

Re:Brains on Drugs: How tinkering with consciousness became ... by headcanon on Thursday June 22, 2023 @01:37PM (#36435812)
The main societal issue is that we've conflated a public health issue with a criminal one, and created a system of perverse incentives and propaganda that ensures that it remains a criminal one. When a drug user is labeled a "criminal" by the state, the role of the state changes from "helping them recover and rehabilitate" to "punish and contain", which helps nobody. Yes we have rehab programs, yes we have non-prison methods for non-violent offenders, but getting the "better" end of the legal system requires the privilege of a good lawyer and knowledge of how to navigate a system that is effectively predatory without one.

You have not said they should be criminalized, but too often the idea "Drugs can be harmful" is followed by "Drug use should be criminalized".

Another point is that not all drugs are the same. Fentanyl is a very different drug than, say, psychedelics, and should be treated as such. A lot of that is also part of the culture of criminalization, where we treat all "illegal" drugs as the same thing, consumed by the same dehumanized "criminals" for the same hedonistic purposes. Which is totally different than "momma's little helper" that some billionaire convinced her doctor to prescribe her.

By the same token, Adderall is a different drug than MDMA, but somehow one of them I'll definitely go to jail for possessing, the other I can get a doctor to prescribe to me.

Re:Brains on Drugs: How tinkering with consciousness became ... by bagacrap on Thursday June 22, 2023 @11:54PM (#36442603)
You know it's not possible to die from shrooms right? All drugs are not heroine.