News for hackers. Stuff that matters.
Re:Brains on Drugs: How tinkering with consciousness became ... by ak_111 on Thursday June 22, 2023 @09:54AM (#36432212)
I think your argument is a bit shaky if you take into consideration alcohol in society.

alcohol consumption is perfectly acceptable, very well-regulated, “safe”, and alcoholics receive plenty of support and sympathy from public health, yet that doesn’t stop alcoholism ripping through society with countless victims (and victims of victims).

You can even make the argument that many alocholics wouldn’t be so if alcohol was less normalised in society

Re:Brains on Drugs: How tinkering with consciousness became ... by throwanem on Thursday June 22, 2023 @10:07AM (#36432394)
The argument has been made before. It didn't turn out all that well, not least because methanol is neurotoxic.
Re:Brains on Drugs: How tinkering with consciousness became ... by nuxi on Thursday June 22, 2023 @10:49AM (#36433002)
I think you meant "ethanol", methanol is fatal to drink even in small doses.
Re:Brains on Drugs: How tinkering with consciousness became ... by throwanem on Thursday June 22, 2023 @11:15AM (#36433429)
No, I meant methanol. It's an easy contaminant to produce through improper distillation practice, and the most common of several contaminants which produced unfortunate outcomes among drinkers of illegal liquor during prohibition.
Re:Brains on Drugs: How tinkering with consciousness became ... by nuxi on Thursday June 22, 2023 @11:54AM (#36434108)
Right, thanks, I missed your point.
Re:Brains on Drugs: How tinkering with consciousness became ... by htag on Thursday June 22, 2023 @12:03PM (#36434255)
Methanol specifically is produced during the distillation process. The methanol vapors and ethanol vapors reside next to each other in the distillation column, making it a common impurity that is brought over in the distillation process. Great care needs to be taken to avoid collecting the methanol.

This simple fact is the greatest argument for distillation having much higher legal barriers than the simple brewing involved in beer/wine/mead.

Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @12:33PM (#36434709)
Distilling doesn't produce jack-diddly-squat. It just concentrates. Methanol is a side effect of the fermentation process, and only common with exotic carbohydrates. In a normal beer, wine, or wash, you'll find less methanol than in your morning glass of orange juice.
Re:Brains on Drugs: How tinkering with consciousness became ... by throwanem on Thursday June 22, 2023 @04:08PM (#36438107)
I don't know what "exotic" means in the context of moonshine, but I've known some mountain men who weren't clever or careful about it and would ferment damn near anything - which is why I've drunk moonshine exactly once, and intend that to remain the case for the balance of my life.

Poking around the web, it seems as if making liquor at home has become popular among booze nerds. That's great and all, but I wouldn't call it moonshine, and I'd be very hesitant about how much I reasoned based on what well-informed people do today about the practices of a century ago, or indeed about the practices of today among those for whom making moonshine is more a family tradition than a hobby.

Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @06:02PM (#36439718)
If it vaguely, and I mean vaguely resembles starch or sugar, you're not getting methanol. It's substantially harder to convert long polysacharides into ethanol/methanol than it is to convert starches and simple sugars, to the point that the less informed a person is, in the off chance they succeeded in making alcohol, the less likely there's going to be substantial methanol levels.

The vast majority of moonshine stills were just churning out unaged corn whiskey from animal feed corn. There is no risk of methanol poisoning in that scenario.

Re:Brains on Drugs: How tinkering with consciousness became ... by dweymouth on Thursday June 22, 2023 @05:48PM (#36439542)
Speaking technically, methanol isn't produced during distillation, it's concentrated. Since it boils at a lower point than ethanol, it disproportionately comes out in the "heads" of a distillation run. The source wine/beer/mash already has all the methanol in it, it's just it's not a problem when present in the small quantities in a non-distilled drink, alongside with a much greater amount of ethanol. (Ethanol can actually act as an antidote to methanol since your body processes it first and can then excrete much of the methanol unmetabolized)
Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @12:30PM (#36434665)
The risk of methanol poisoning in moonshine is grossly overrated. Simply put, you have to do some stupid shit to end up with dangerous amounts of methanol. The methanol content in a beer, wine, or mash precursor to liquor production will be absolutely trivial, unless you are are doing something ridiculous like trying to make liquor from tree bark (the Greeks have a drink like this, it's heavily warned against in home distilling circles).

So why was methanol poisoning common during the Prohibition? Renatured fuel alcohol. To stop people from drinking fuel ethanol, the government poisoned the supply with methanol. People tried to come up with jerry-rigged solutions to remove the methanol, and more often than not failed. Some less scrupulous experimenters sold their results anyway, where it worked its way into the black market supply chain.

Re:Brains on Drugs: How tinkering with consciousness became ... by steppi on Thursday June 22, 2023 @11:10AM (#36433341)
Not that ethanol isn't also neurotoxic (to a much lesser degree), but bootleg moonshines common during prohibition often contained trace amounts of methanol, the number of people irreversibly injured by methanol poisoning greatly exceeded the number who died.

By 1926, according to Prohibition, by Edward Behr, 750 New Yorkers perished from such poisoning and hundreds of thousands more suffered irreversible injuries including blindness and paralysis. [0]

[0] https://content.time.com/time/specials/packages/article/0,28...

Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @11:53AM (#36434102)
Didn't the government also add methanol to non-consumption alcohol products as well, contributing to those poisoning numbers?
Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @12:37PM (#36434783)
This was likely the cause of the vast majority of methanol poisonings during the prohibition. You have to use exotic, hard to break down carbohydrates in your beer, wine, or mash (the pre-distillation fermented product), like tree bark, to end up with significant quantities of methanol.

Most of the methanol poisonings were from poorly "re"natured fuel alcohol.

Re:Brains on Drugs: How tinkering with consciousness became ... by steppi on Thursday June 22, 2023 @12:25PM (#36434585)
Yeah, industrial alcohols were (and still are) "denatured" with additives to make them toxic or unpalatable and industrial alcohol was often used as a precursor for bootleg spirits during prohibition. I think modern denaturants lean more towards unpalatable than toxic.
Re:Brains on Drugs: How tinkering with consciousness became ... by bittercynic on Thursday June 22, 2023 @11:07AM (#36433281)
I think GP was referring to the increase in methanol poisoning during prohibition.
Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @11:52AM (#36434086)
Prohibition reduced american alcohol consumption by about a third according to most estimates, and before it, americans were drinking insane amounts of hard liquor. Like the equivalent of multiple drinks a day.
Re:Brains on Drugs: How tinkering with consciousness became ... by pstuart on Thursday June 22, 2023 @01:32PM (#36435746)
It also promoted a lot of organized crime. Just like today (but worse, because now we have narco-states vs just gangs.

I lost a mother to alcohol and a brother to heroin. Both are technically quite safe when used appropriately and lethal when not. And they're going to be used regardless of legality, so let's make it safer for those that do as well as stop funding the cartels.

Re:Brains on Drugs: How tinkering with consciousness became ... by ak_111 on Thursday June 22, 2023 @01:35PM (#36435782)
I am sorry about your loss. However, if you want to talk technically, then the science over the last two decades has moved almost decisively to saying there is no safe level of alcohol consumption.
Re:Brains on Drugs: How tinkering with consciousness became ... by throwanem on Thursday June 22, 2023 @01:54PM (#36436083)
There's also no safe level of organized crime.
Re:Brains on Drugs: How tinkering with consciousness became ... by pstuart on Thursday June 22, 2023 @04:11PM (#36438153)
Yeah, alcohol is not healthy for people. But by safe I'm talking about a glass of wine with dinner or other low intake/healthy contexts.

But my point stands: people are going to do it regardless of the law, so let's stop criminalizing it. Being overweight is unhealthy too, should we arrest every fat person in the country "for their own good"?

Re:Brains on Drugs: How tinkering with consciousness became ... by mrguyorama on Thursday June 22, 2023 @05:42PM (#36439465)
I'm not in favor of banning alcohol. I just want to dispel the false notion that prohibition didn't "work", when it empirically did.

We shouldn't ban alcohol because it's a hamfisted way to reduce alcoholism and harms from alcohol abuse. However, the 1910s didn't exactly have functioning rehabilitation programs.

Re:Brains on Drugs: How tinkering with consciousness became ... by pstuart on Friday June 23, 2023 @01:07PM (#36449611)
It might have worked if you squinted right. There was still plenty of alcohol for those of means.

Again, it came at a cost of organized crime. It was not a win.

Re:Brains on Drugs: How tinkering with consciousness became ... by LocalH on Saturday June 24, 2023 @10:45AM (#36459096)
We don't really have a functioning rehabilitation program now. The rates of failure and relapse are not exactly low. There are also often a bunch of hoops to jump through to even get access to them, most people are more interested in being "tough on crime" which really means "authoritarian".
Re:Brains on Drugs: How tinkering with consciousness became ... by goolz on Friday June 23, 2023 @08:01AM (#36445662)
Heroin, in a pure form, is non-toxic and as long as you don’t mix it with things and do too much you should be OK. Proper dosing is the huge part. But you could still easily die from slowing your heart down too much so I would not say “safe”. Non-toxic, let’s stick with that.
Re:Brains on Drugs: How tinkering with consciousness became ... by smoldesu on Thursday June 22, 2023 @10:12AM (#36432459)
> You can even make the argument that many alocholics wouldn’t be so if alcohol was less normalised in society

Didn't American and European prohibition vehemently disprove this theory?

Re:Brains on Drugs: How tinkering with consciousness became ... by runsWphotons on Thursday June 22, 2023 @10:37AM (#36432814)
Prohibition actually worked relatively well.
Re:Brains on Drugs: How tinkering with consciousness became ... by pixl97 on Thursday June 22, 2023 @10:54AM (#36433076)
It reduced harm until it started to increase harm.

At the end of the day human vice isn't going away.

Re:Brains on Drugs: How tinkering with consciousness became ... by skulk on Thursday June 22, 2023 @10:56AM (#36433117)
It's not useful to judge prohibition in a single dimension of "work well" to "didn't work". Sure, cirrhosis rates went down significantly but organized crime (a disease of its own) was gifted a torrent of money to fuel other activities.
Re:Brains on Drugs: How tinkering with consciousness became ... by joncrane on Thursday June 22, 2023 @11:28AM (#36433647)
It was a "loud minority" type of thing. The average person simply stopped drinking, which was fine.

In today's market, 10% of the drinkers consume 90% of the alcohol. So the efforts of the 10% and the people serving the 10%, and the efforts of law enforcement to stop them, resulted in many very high profile, violent events, which made it seem like it wasn't worth the effort.

Full disclosure, I'm an alcoholic in recovery and I'd be fine with alcohol being illegal. My main beef is that the laws are not internally consistent: THC is by far a milder drug than alcohol but alcohol is legal while THC is still mostly illegal in the US (federally).

Either legalize THC completely or ban alcohol if you want to be consistent.

Also worth noting, THC (at less than 0.3% which is plenty for gummies) and many very very close, but naturally occurring (in infinitesimal amounts) are technically legal federally and companies like 3CHI are exploiting those loopholes. You can buy a vape containing things like HHC, THC-P, THC-O, etc which is virtually indistinguishable from Delta-9 THC, so obviously the days of THC being illegal are numbered.

Re:Brains on Drugs: How tinkering with consciousness became ... by danenania on Thursday June 22, 2023 @11:56AM (#36434154)
But the people who are the problem drinkers still end up finding a source of alcohol. So now moderate drinkers have been prevented from having their drink or two, alcoholics are drinking just as much, but are more likely to be poisoned, and you’ve created a massive cash cow for organized crime. How is that anything but a total failure?
Re:Brains on Drugs: How tinkering with consciousness became ... by bfuller on Thursday June 22, 2023 @12:49PM (#36435043)
There are even better loopholes than that.
Re:Brains on Drugs: How tinkering with consciousness became ... by nosmokewhereiam on Thursday June 22, 2023 @01:19PM (#36435532)
If anyone can explain the THCA loophole, it'd explain how they are shipped directly to consumer.

It's the wild west but across the US. How is this possible, and will it be open until it's legalized federally?

"Why even get a license" is the incentive this creates.

Re:Brains on Drugs: How tinkering with consciousness became ... by OkayPhysicist on Thursday June 22, 2023 @07:29PM (#36440685)
On the other hand, you can look at the vast majority of society that drinks in perfectly reasonable moderation. Teetotalers make up a tiny fraction of society, yet civilization hasn't crumbled to barbarism. If a community is experiencing alcoholism at such a rate that it's "ripping through society", then that suggests to me that there's a greater root evil than the bottle.
Re:Brains on Drugs: How tinkering with consciousness became ... by schrodinger on Thursday June 22, 2023 @09:19PM (#36441582)
Actually, you'd be surprised to learn that 20–40% of Americans don't drink. There are all different ways to define it leading to the ambiguous statistics (e.g. once a year, never, include/exclude under 21 year olds), but either way I found it very surprising how many people don't actually drink alcohol.
Re:Brains on Drugs: How tinkering with consciousness became ... by WastingMyTime89 on Friday June 23, 2023 @06:20AM (#36444934)
> “safe”

No idea of why you quote the word. Alcohol consumption is demonstrably unsafe. The estimate is that alcohol kills around 140 000 people per year in the USA. It's just legal because criminalisation was tried and proven to be not only useless but actually more harmful to society through its side effects, a situation similar to the one we are still having with all the other drugs which are still illegal basically.