(You somehow get the full article via https://www.iflscience.com/humans-may-be-causing-cancer-in-o...)
Here is a site you can use too see how most pharmaco therapy is lacking.
https://pain-calculator.com/calculators/osteoarthritis-pain/
Very few painkillers that are not blood thinners. Paracetamol and canabinoids are a couple of rare exceptions.
My uncle broke his hip in his old age. He died shortly after because of the bleeding induced by painkillers.
What all that, how can you defend opiates? Opinion of society is irrelevant here, they are absolute scourge if used enough, and nobody is immune.
i do argue that in the correct harness, opiates could be distributed to minimize unnecessary suffering at least somewhat - not 24/7, because literally any drug will result in tolerance (and debilitating physical side effects, something opiates lack) at that point. our current system is unsatisfactory - people are not taught how to take drugs correctly, and people exist in a system that naturally causes dopamine seeking reward systems to malfunction. while some are born psychologically weak, inherently leading to addiction susceptibility, society is expressly designed to produce such weakness in order to maintain the status quo. of course such an environment is not positively conducive to the dopamine flooding effects of opiates. i dont blame opiates for the system in which they exist.
regarding personality cracks, i still refer to rat park for the most part, saving brain resets such as ibogaine for extreme cases - our addiction inducing society (as a whole, not merely the opinions wherein) does not imply impossibility of rewiring addictions. regardless, some people think cracks are beautiful (ref. kintsugi).
do you argue that everyone should be instead placed on nsaids that destroy the stomach and liver, killing them earlier and objectively adding pain prior? is the current trajectory (that is, entirely depriving the suffering of effective relief, regardless as to their age bracket) for the best?
NSAIDs are known to kill your stomach, your kidney, your liver, and your heart, whereas opiates do not. And they are ineffective for a lot of people's chronic pain, on top of that.
in a few years when non opiate drugs are cheap, opiates will go the way of benzos (only prescribed by older doctors who learned under different guidelines). then chronic pain sufferers will get no pleasure at all, merely a dull blunting. and everyone will be okay with it, the same way they are okay with schizophrenics being unnecessarily blunted due to society.
I was thinking the same thing. There is no way people who have chronic pain are saying these things. And if you think about it, it is sickening that people who are fine and do not have chronic pain are the ones dismissing a painkiller, or are trying to dictate someone else's life because they heard opiates are bad (opioid crisis, war on drugs).
And yeah, everyone will be okay with it. Sometimes I really wish people were in my shoes... We need more people experiencing it, otherwise we really are f....d (because they lack empathy, it seems). Good comparison to schizophrenia, by the way.
I really hope that you are wrong though. :/
(BTW, any way I could reach out to you?)
ive come to the point where straight up forcing people into church to be told they are selfish 1x a week is probably the best solution. if a secular version could exist id be all ears, frankly i dont care if god is real or not, people dont follow the commandments and society would be better off if everyone did.
i made a reddit account under this handle a little while back, although it was immediately banned. so i couldnt respond, but i could recieve your email address there and reach out myself.
In this case some public reads "smoking a joint daily equals invulnerable to Alzheimer, science says so".
If you make a product you can make a study that shows it has some kind of benefit in some specific way, even if it probably causes more harm in other ways that are less obvious, and then you can sell it. Media will spread around your study especially if it shows something that will be a bit click-baity, and any study or discussion of the possible downsides will get far less attention.
This is also why basically every edible plant has some article saying it's a "super food" etc etc.
[rolls eyes]
lots of anecdotal evidence suggests donnie t like stimulants, esp. the kind that you can put up your nose.
this would require 3 joints of ~ 300 mg cannabis at ~ 30% THC content.
the legendary MTF strain regularily trumpets a 25-30% THC content.
now if bioavailability is 30% that means you need 9 or 10 joints to get a 1 micro molar total dosage. that dose is distributed across body mass.
at this point, i cant say i could conceive of anyone smoking basically an 1/8 ounce of MTA in one day, let alone at one sitting, and doing that for 6 days in a row sounds frightening, not recreational.
I don’t know what levels are achieved during normal use but I did find some studies that successfully killed a lot of hippocampal neuronal cells after 6 days at 1uM range. So the levels of THC observed in this study appear to be in the same range where things start getting really disrupted in cells.
In other words, don’t expect to replicate these results with normal recreational use.