News for hackers. Stuff that matters.
Re:I’m not convinced by the new lab leak debunking by rossdavidh on Saturday March 05, 2022 @06:00PM (#30572837)
"But we should keep in mind that the virologists publishing papers downplaying the possibility of a lab leak are not disinterested parties in this. The political context is a debate about regulating virus labs, and it’s hardly shocking that a large segment of the virus lab community doesn’t like that idea."

This, I think, is the crux of our problem. Almost anyone who knows enough about the field to have an informed opinion, is involved enough to have an incentive to convince the world that it was not their profession, that unleashed this. Scientists are human, not demons but also not angels. It would be hard to convince yourself, that your profession was responsible for this. We should listen to what they have to say, but not expect them to be dispassionate and unbiased investigators of the question.

Re:I’m not convinced by the new lab leak debunking by 323 on Saturday March 05, 2022 @07:49PM (#30573757)
On the TWiV (This Week in Virology) podcast at one point they discussed what would be some of the consequences if the lab leak theory were to be proven.

One aspect mentioned was that all the virology labs doing dangerous research would be moved outside of big cities. Then they concluded that such an act would be a terrible thing to do, since no virologist would want to work and live in the middle of nowhere.

Re:I’m not convinced by the new lab leak debunking by WalterBright on Saturday March 05, 2022 @09:16PM (#30574366)
The genesis of JPL (Jet Propulsion Laboratory) was rocket researchers doing it on the Caltech campus and the community fearing explosions. So JPL was created out of town, and named "Jet" instead of "Rocket" because it sounded less dangerous.
Re:I’m not convinced by the new lab leak debunking by dmix on Saturday March 05, 2022 @11:20PM (#30574997)
I could imagine a university town or the Russian style nuclear cities developing. You go there for a certain industry and a mini culture develops, people understand the trade offs.

It doesn’t have to be a negative thing but I do understand that getting pushed out of all urban areas in a hostile NIMBY culture we’ve developed could very well limit the field in many ways.

Re:I’m not convinced by the new lab leak debunking by twaw on Sunday March 06, 2022 @01:53AM (#30575596)
World is interconnected a lot right now by planes. For example, Novosibirsk is low populated area in the middle if nowhere, but it just 2 hours by plane to heavily populated China. BSL4 Lab Vector was created in relatively safe area, but now it is not safe anymore. The blast in Vector lab on Sep 16 2019 took immediate attention of scientific world, because blast is able to put virus particles into air from hidden surfaces, which cannot be cleaned properly. Scintists recommended to put Novosibirsk into carantine for 2 weeks at least, but Russians ignored that.
Re:I’m not convinced by the new lab leak debunking by travisjungroth on Saturday March 05, 2022 @11:59PM (#30575158)
> people understand the trade offs.

Or 90% do and 10% want to shut down the thing depressing their property values. The problem is that 10% votes and shows up to city council meetings.

Re:I’m not convinced by the new lab leak debunking by itronitron on Sunday March 06, 2022 @03:45AM (#30576066)
Yeah, and the local High School mascot could be the 'Vector'

>> http://america.aljazeera.com/multimedia/2015/7/richland-wash...

Re:I’m not convinced by the new lab leak debunking by relaxing on Sunday March 06, 2022 @01:02AM (#30575402)
MIT Lincoln labs shares a similar origin story.

The idea that postdoc researchers are on the whole a bunch of hipster urbanites is laughable.

Re:I’m not convinced by the new lab leak debunking by ddddfdohvsyknn on Saturday March 05, 2022 @11:22PM (#30575008)
Covid has killed an order of magnitude more people than atomic weapons. We got to learn the hard way how destructive viruses can be. People clutching pearls over the potential to mislead are missing the point. There should be a frank and critical discussion about the risks of viral research, especially near populated areas. But entertaining the possibility of a catastrophic accident is now considered conspiratorial thinking
Re:I’m not convinced by the new lab leak debunking by sgt101 on Sunday March 06, 2022 @03:10AM (#30575900)
>Covid has killed an order of magnitude more people than atomic weapons.

so far.

Current events point to a possible future that remembers covid as a footnote to the events this year.

Re:I’m not convinced by the new lab leak debunking by jjeaff on Sunday March 06, 2022 @01:09AM (#30575435)
So I assume you also think the US should destroy all of its nuclear weapons today?

You will never, ever keep people safe from something by plugging your ears and pretending it doesn't exist.

The fact that viruses can cause so much damage is exactly why we need even more research into dangerous viruses, not less.

Re:I’m not convinced by the new lab leak debunking by serial_dev on Sunday March 06, 2022 @02:01AM (#30575623)
> The fact that viruses can cause so much damage is exactly why we need even more research into dangerous viruses, not less.

Isn't this line of thinking going to create a dangerous feedback loop?

Scientists experiment to create the deadliest virus yet, this virus leaks (because part of being very dangerous is being very contagious), killing many, shutting down our life as we know it for years.

And what did we learn from it? We need more research, we need to experiment and create even more dangerous viruses, because it can cause so much damage?

Then repeat?

That's not going to end well (but I'm afraid that will happen).

Re:I’m not convinced by the new lab leak debunking by jjeaff on Sunday March 06, 2022 @08:07PM (#30582967)
Yes, it might create a feedback loop. But the fact is, no matter what the good guys do, the bad guys are going to keep at it. The only alternative is to try and stay ahead of the bad guys.
Re:I’m not convinced by the new lab leak debunking by justatdotin on Sunday March 06, 2022 @10:08PM (#30583801)
> good guys

   ^-- found the bug
Re:I’m not convinced by the new lab leak debunking by jay_kyburz on Sunday March 06, 2022 @03:00AM (#30575848)
How is knowing more about Nukes keeping us safe from Nukes?

All nukes should be decommissioned, and all countries should be open to independent inspectors. (I will never happen, but it _should_). This week, of all weeks, this should be clear.

Re:I’m not convinced by the new lab leak debunking by jjeaff on Sunday March 06, 2022 @08:08PM (#30582982)
And we should also have world peace and we should also end world hunger. That doesn't make either of those things happen.

Not staying ahead of the curve just means someone else will.

Re:I’m not convinced by the new lab leak debunking by spopejoy on Monday March 07, 2022 @06:17PM (#30594627)
Non-proliferation treaties were a thing until the US decided not to play ball in the 90s. It is entirely feasible to conceive of nuclear containment via treaties, and indeed the world was headed in this direction after the cold war.

It doesn't help that any nuclear plant can make a "dirty bomb" btw, which is one more reason to be anti-nuclear. No nukes, no nuke weapons. Not a bad tradeoff all by itself. (And yes, such bans can be enforced, look no further than Iran's difficulty getting nuclear power going).

Re:I’m not convinced by the new lab leak debunking by dragonwriter on Monday March 07, 2022 @06:21PM (#30594651)
> Non-proliferation treaties were a thing until the US decided not to play ball in the 90s.

The Non-Proliferation Treaty is still a thing, and the US still plays ball with it.

Arms limitation treaties were an important thing until the US scrapped the ABM Treaty in 2002, followed almost immediately by Russia dumping START II, which is the closest real thing I can think of to what you said, differing in the kind of treaty involved and the decade the wheels came off.

Re:I’m not convinced by the new lab leak debunking by spopejoy on Monday March 07, 2022 @06:46PM (#30594834)
It's oversimplifying a lot to say Russia "dumped START II" given the dishonesty surrounding US nukes in Europe at the time. NATO's "nuclear sharing" makes a mockery of NPT. There's the USs historic support of Israel not joining NPT. And so on ... the US is not serious about non-proliferation, to say the very least.
Re:I’m not convinced by the new lab leak debunking by dragonwriter on Monday March 07, 2022 @09:28PM (#30595792)
> It's oversimplifying a lot to say Russia "dumped START II"

It is perfectly accurate to say that they did so (and that it was a direct response to the US withdrawing from the ABM Treaty.)

> NATO's "nuclear sharing" makes a mockery of NPT

NATO’s nuclear sharing agreements predate the NPT, and no new ones have been entered since the NPT, and the continuation of the existing ones is consistent with the NPT.

Re:I’m not convinced by the new lab leak debunking by justatdotin on Sunday March 06, 2022 @09:52PM (#30583711)
you're on the rong curve.
Re:I’m not convinced by the new lab leak debunking by chernevik on Monday March 07, 2022 @01:12PM (#30591258)
No more likely than decommissioning guns. Or swords.
Re:I’m not convinced by the new lab leak debunking by spopejoy on Monday March 07, 2022 @06:22PM (#30594662)
Non-proliferation is possible if democracies like the US weren't determined to sabotage them. I say democracies because in theory they do what their population wants, and NPTs faced no opposition in the 90s (except from defense contractors of course).

Now it's too late for this crisis (and possibly humanity) but we must demand NPTs if/when this crisis is resolved.

Re:I’m not convinced by the new lab leak debunking by ddddfdohvsyknn on Sunday March 06, 2022 @01:26AM (#30575497)
Viral research is useful I'm sure it just annoys me when the media is framing the lab leak theory as some absurd and incredibly unlikely possibility. My point is that like a nuclear exchange a low probability times a lot of damage is high risk
Re:I’m not convinced by the new lab leak debunking by doingtheiroming on Sunday March 06, 2022 @02:52AM (#30575818)
Nuclear weapons are reasonably well controlled. I’d love to know that they were better controlled than they are though. The same applies to virus research.
Re:I’m not convinced by the new lab leak debunking by justatdotin on Sunday March 06, 2022 @04:50PM (#30581627)
> So I assume you also think the US should destroy all of its nuclear weapons today?

yes please.

Re:I’m not convinced by the new lab leak debunking by jjeaff on Sunday March 06, 2022 @08:10PM (#30582997)
Surely you don't think that would be a good idea? That leaves Russia with the most powerful weapons on earth. Something makes me think that wouldn't end well for the rest of the world.
Re:I’m not convinced by the new lab leak debunking by justatdotin on Sunday March 06, 2022 @10:10PM (#30583816)
your logical fallacies include: * 'good guy' with a gun * mutually asssured destruction * american exceptionalism

yes of course all nuclear WMD states (not just the biggest) need to abandon this losing game.

The good news is the rest of us have called time: https://banmonitor.org/tpnw-status

Re:I’m not convinced by the new lab leak debunking by WanderPanda on Sunday March 06, 2022 @12:46AM (#30575335)
If it is „just“ one order of magnitude then I would argue that the loss in quality adjusted lifetime is much lower given the demographics of severe covid cases
Re:I’m not convinced by the new lab leak debunking by alfor on Sunday March 06, 2022 @01:04AM (#30575411)
Maybe not if you account for long covid.

Many people got lost many year of life but don’t even know it.

The fact that it affect heart muscle that have almost no regenerative capacity is chilling.

Re:I’m not convinced by the new lab leak debunking by hetspookjee on Saturday March 05, 2022 @07:58PM (#30573832)
As terrible as that may sound I wonder if they thought about the idea to move nuclear reactors back into big cities for the convenience of the people working in them. Sound as if they neither see a problem with that.
Re:I’m not convinced by the new lab leak debunking by scotty79 on Saturday March 05, 2022 @08:19PM (#30573972)
Actually moving reactors (back?) into the cities would be a great move because that would make people understand how incredibly safe those thing are.

Meanwhile we have coal power plants in the cities spewing out harmful particulates, gases and even radiation and people percieving them as safe because they live next to them.

Re:I’m not convinced by the new lab leak debunking by cronix on Saturday March 05, 2022 @08:45PM (#30574155)
A lot (most?) of them are. Trojan, in Portland Oregon, wasn't. It left a bitter taste in the mouths of many Oregonians, especially the main population center of the state in Portland, to the point the basically banned it. Also a lot of Washingtonians were not happy that the leftover nuclear waste was buried up in their state as well as increased radioactive levels in the Columbia River detected since then, and higher than average deformation of fish. It was on the ballot year after year to get it closed down and finally leaked docs from the US NRC sealed the deal. I got to watch them blow it up! :)

> After 16 years of irregular service, the plant was closed permanently in 1992 by its operator, Portland General Electric (PGE),[3] after cracks were discovered in the steam-generator tubing. Decommissioning and demolition of the plant began the following year and was largely completed in 2006

> The Trojan steam generators were designed to last the life of the plant, but it was only four years before premature cracking of the steam tubes was observed.[citation needed] In October 1979, the plant was shut down through the end of the year for repairs.[14][15][16] The plant had an extended shutdown in 1984, with difficulty restarting.

> In December 1992, documents were leaked from the U.S. Nuclear Regulatory Commission showing that staff scientists believed that Trojan might be unsafe to operate.[26] In early January 1993, PGE chief executive Ken Harrison announced the company would not try to restart Trojan

> In 2005, the reactor vessel and other radioactive equipment were removed from the Trojan plant, encased in concrete foam, shrink-wrapped, and transported intact by barge along the Columbia River to Hanford Nuclear Reservation in Washington, where it was buried in a pit and covered with 45 feet (14 m) of gravel, which made it the first commercial reactor to be moved and buried whole.[31] It was awaiting transport to the Yucca Mountain Repository until that project was canceled in 2009.

https://en.wikipedia.org/wiki/Trojan_Nuclear_Power_Plant

Re:I’m not convinced by the new lab leak debunking by unfocussed_mike on Saturday March 05, 2022 @11:25PM (#30575024)
Random factoid: Kodak had a small nuclear reactor in the basement of its Rochester, NY headquarters for thirty years (until the plant and HQ was closed).

Emphasis on small. Not a true secret; fully regulated and licensed. But they didn't talk about it!

https://www.independent.co.uk/news/world/americas/kodak-reve...

"...it came pre-loaded with nearly 1.5kg of uranium enriched up to a level of 93.4 per cent, which is just about right for an atomic warhead."

Re:I’m not convinced by the new lab leak debunking by thesz on Saturday March 05, 2022 @11:55PM (#30575139)
https://eng.mephi.ru/research/facilities/the-reactor

I think it is about 10-15km from center of Moscow.

Re:I’m not convinced by the new lab leak debunking by Tabular-Iceberg on Sunday March 06, 2022 @03:26AM (#30575979)
Another advantage is that it would become practical to use the waste heat for district heating.
Re:I’m not convinced by the new lab leak debunking by sumedh on Sunday March 06, 2022 @05:09AM (#30576408)
Do you want a nuclear plant near your backyard?
Re:I’m not convinced by the new lab leak debunking by naasking on Sunday March 06, 2022 @12:44PM (#30579312)
If it meant not having fossil fuel plants nearby instead, I 100% would want a nuclear pant near my backyard. Perhaps you don't realize how many people die per year due to air pollution. Comparing the safety records of fossil fuels and nuclear is frankly laughable.
Re:I’m not convinced by the new lab leak debunking by justatdotin on Sunday March 06, 2022 @04:57PM (#30581689)
Comparing the safety records of fossil fuels and nuclear, while ignoring the safety of solar, is dishonest. >150% of my power requirements is produced by panels on my roof.
Re:I’m not convinced by the new lab leak debunking by naasking on Sunday March 06, 2022 @11:07PM (#30584131)
If it feels dishonest, then you should do more research. Nuclear is safer than solar too:

https://www.iaea.org/sites/default/files/publications/magazi...

Re:I’m not convinced by the new lab leak debunking by justatdotin on Sunday March 06, 2022 @11:27PM (#30584226)
do you have a supporting reference from this century?

or at least, more recent than Chernobyl?

Re:I’m not convinced by the new lab leak debunking by godelski on Monday March 07, 2022 @03:31AM (#30585451)
I do[0]

> the death toll of history’s two nuclear disasters we have added the death rate that Markandya and Wilkinson (2007) estimated for occupational deaths, most from milling and mining. Their published rate is 0.022 deaths per TWh.

> The sum of these three data points gives us a death rate of 0.07 deaths per TWh. We might consider this an upper estimate.

> For example, included in this database were deaths related to an incident where from a water tank ruptured during a construction test at a solar factory. It’s not clear whether these supply chain deaths should or shouldn’t be attributed as a death from solar technologies.

Deaths: Nuclear 0.07 vs Solar 0.02.

Greenhouse gasses: Nuclear 3 tonnes vs Solar 5 tonnes

Here's one from 2012[1] where they breakdown nuclear deaths to include Chernobyl and Fukushima and remove those (i.e. electricity). Nuclear wins by a lot.

Or a 2014 study[2] showing nuclear beating solar rooftop (note, concentrated solar is a lot safer than rooftop. Concentrated is actually safer than nuclear but the death rates are so small I'm not sure why we're arguing over them).

There's plenty of sources showing nuclear's death rates are roughly the same as solar, wind, and hydro. All of which are 2 orders of magnitude below biomass and natural gas and 3 below coal and oil. Similarly also 2-3 orders of magnitude less than coal, natural gas, and oil (1 magnitude less than hydro).

These discussions are absurd. We just end up sitting here quibbling over a small tradeoff between emissions and deaths (a very difficult thing to measure) while we just keep producing gas, oil, and coal. Pick your battles. When we have a clean grid we can quibble over these numbers because at that point they will be significant. But at this time they aren't even close. If you want to complain about the cost of nuclear, sure, that's a fair and honest discussion we can have. But there is no evidence to suggest that nuclear isn't safe and green. This is very concerning when it represents 50% of the zero carbon emission energy in the US.

[0] https://ourworldindata.org/safest-sources-of-energy

[1] https://www.forbes.com/sites/jamesconca/2012/06/10/energys-d...

[2] https://www.researchgate.net/figure/rates-for-each-energy-so...

Re:I’m not convinced by the new lab leak debunking by justatdotin on Monday March 07, 2022 @04:08AM (#30585680)
you know what's really absurd? you started off with a 50yo source claiming solar has >100 times the deaths of nuclear, then fell back to claims that they're 'roughly the same' and 'just a small tradeoff' but go on to say there is no evidence nuclear isn't safe.

I've picked my battle and I've picked a winner. solar has been giving me more power than I know what to do with for years. More than 10% of my suburb has rooftop, there are 3 small grid arrays within 100k, and a 10gw plant being built down the highway that will produce enough untapped energy to kickstart new manufacturing.

Re:I’m not convinced by the new lab leak debunking by godelski on Monday March 07, 2022 @01:05PM (#30591175)
You know I'm a different person, right?

> More than 10% of my suburb has rooftop, there are 3 small grid arrays within 100k

Great! I'm not anti-solar. Nor is anyone I know that is pro-nuclear. We tend to also be pro-renewables. It is just that nuclear shouldn't be taken off the table when we're facing a crisis.

Re:I’m not convinced by the new lab leak debunking by justatdotin on Tuesday March 08, 2022 @09:22AM (#30600157)
sorry, that's two fumbles in one day. I gotta slow down :(
Re:I’m not convinced by the new lab leak debunking by godelski on Monday March 07, 2022 @03:18AM (#30585383)
Yes. Why not? In fact, I grew up next to one. Swam in the ocean next to it. Fished near it.
Re:I’m not convinced by the new lab leak debunking by enraged_camel on Saturday March 05, 2022 @08:31PM (#30574053)
>> Then they concluded that such an act would be a terrible thing to do, since no virologist would want to work and live in the middle of nowhere.

I mean, this is a solved problem in many fields. In medicine, for example, the way you convince good doctors and nurses to work in rural hospitals is to pay them a lot more.

Re:I’m not convinced by the new lab leak debunking by Calavar on Saturday March 05, 2022 @10:23PM (#30574742)
This is far from a solved problem in medicine. Higher salaries aren't enough to attract the number of doctors are needed, and there are also other issues that actively drive away doctors. (For example, fewer doctors to split the call pool in rural areas means that doctors may need to work more nights and weekends than they would in urban areas.)
Re:I’m not convinced by the new lab leak debunking by nostrademons on Saturday March 05, 2022 @10:37PM (#30574814)
That would require 1) budgeting more money for science or 2) hiring fewer scientists. Recent U.S. history has very much shown us unwilling to do 1), which means that we're going to get 2). I'm pretty sure that's not really an outcome scientists want either, and arguably it'd be bad for the nation's long-term competitiveness.
Re:I’m not convinced by the new lab leak debunking by nyanpasu64 on Saturday March 05, 2022 @09:06PM (#30574303)
On the other hand, I hear stories that VA has difficulty hiring doctors in rural areas, and ends up hiring bad doctors who harm patients.
Re:I’m not convinced by the new lab leak debunking by bradleyjg on Saturday March 05, 2022 @09:10PM (#30574336)
The VA and the government in general underpays doctors and white collar workers in general.
Re:I’m not convinced by the new lab leak debunking by nopenopenopeno on Saturday March 05, 2022 @10:52PM (#30574885)
Are you intentionally implying that the blue collar workers are paid fairly but the white collar workers are not? That takes some serious nerve!
Re:I’m not convinced by the new lab leak debunking by KerrAvon on Saturday March 05, 2022 @11:21PM (#30575002)
In the specific context of government work? Do you have evidence either way?
Re:I’m not convinced by the new lab leak debunking by bradleyjg on Sunday March 06, 2022 @12:21AM (#30575246)
Yes. In some cases overpaid. That’s how the federal civil service system works. Not sure why that’s offensive…
Re:I’m not convinced by the new lab leak debunking by anamax on Saturday March 05, 2022 @09:07PM (#30574313)
The Mayo Clinic started in the middle of no-where.
Re:I’m not convinced by the new lab leak debunking by MaxBarraclough on Sunday March 06, 2022 @06:26AM (#30576759)
> all the virology labs doing dangerous research would be moved outside of big cities

I imagine that might be helpful in making it more likely that an outbreak could be contained, but I wonder by how much. If I understand correctly the Pirbright Institute in England has a history of leaks, and is believed to have caused the 2007 outbreak of foot-and-mouth disease. The lab is situated far from cities, but that didn't stop the outbreak. [0]

(Of course, as foot-and-mouth disease affects livestock, rather than people, I imagine that putting the lab in a city might actually have been better in that particular case.)

[0] https://en.wikipedia.org/wiki/2007_United_Kingdom_foot-and-m...

Re:I’m not convinced by the new lab leak debunking by pbj1968 on Saturday March 05, 2022 @11:51PM (#30575127)
Inevitably what happens is “middle of nowhere” eventually becomes “middle of the city.” Look to the BSL4 primate lab in San Antonio to observe this phenomenon.
Re:I’m not convinced by the new lab leak debunking by mtmsr on Sunday March 06, 2022 @01:51AM (#30575584)
So what would be the difference? Through the lab-leak discussion we have identified labs as a _potential_ threat that need tighter security measures. Even if this virus did not originate in a lab we are just waiting for one that actually does.
Re:I’m not convinced by the new lab leak debunking by hef19898 on Sunday March 06, 2022 @03:52AM (#30576098)
As far as media and general public are concerned, maybe. Everyone that watched one of the pandemic films of the 90s, or spend more then 5 minutes thinking about this stuff, figured that out long ago.
Re:I’m not convinced by the new lab leak debunking by tim333 on Sunday March 06, 2022 @08:22AM (#30577419)
I'm not sure the outside big cities would make much difference given how these things spread. Lab worker gets it, goes home, partner flies to a conference etc.
Re:I’m not convinced by the new lab leak debunking by vitaflo on Saturday March 05, 2022 @10:15PM (#30574698)
This feels a little strange since Rocky Mountain Lab is in Hamilton, MT which I think many people would consider in the "middle of nowhere".
Re:I’m not convinced by the new lab leak debunking by tacitusarc on Sunday March 06, 2022 @01:27AM (#30575504)
TWIV has some very smart, very biased people, who are entirely incapable of recognizing their own biases. A shame, really.
Re:I’m not convinced by the new lab leak debunking by andrewclunn on Saturday March 05, 2022 @08:02PM (#30573854)
Which episode was that?
Re:I’m not convinced by the new lab leak debunking by 323 on Saturday March 05, 2022 @08:08PM (#30573897)
Sorry, I don't know the exact episode. When the lab leak theory started being taken seriously by the media - end of 2020 start of 2021.
Re:I’m not convinced by the new lab leak debunking by prpl on Saturday March 05, 2022 @09:07PM (#30574319)
In practice, this looks like Dugway Proving Grounds in Utah.
Re:I’m not convinced by the new lab leak debunking by hef19898 on Sunday March 06, 2022 @03:18AM (#30575935)
So the basis of the theory that virologists would do everything to hide a lab leak is, hold fast, that virologists don't want a long commute.

That is what it looks like whem you run of straws to grasp in order to maintain your favorite theory...

Re:I’m not convinced by the new lab leak debunking by anshorei on Sunday March 06, 2022 @05:37AM (#30576531)
How about: they don't want to lose their jobs.

And they don't have to cover up a lab leak, nearly all of them are not involved in any lab leak to cover up, most may just be unwilling to believe that it could've been a leak for personal convenience.

Re:I’m not convinced by the new lab leak debunking by chiefalchemist on Saturday March 05, 2022 @07:57PM (#30573820)
They don't want to work in the middle of nowhere? But they're comfortable with the possibility of an international pandemic?

So the science doesn't trust The Science?

Re:I’m not convinced by the new lab leak debunking by ethbr0 on Saturday March 05, 2022 @09:47PM (#30574547)
There's a constant, non-zero possibility of a (international-implied-by-the-term) pandemic. And even if this one was a lab leak, chances are extremely high the next will be zoonotic spillover.

So pathologists and virologists see reality as a default high risk of pandemic, with an optional managed risk of high-BSL research labs near population centers. And that total risk is dominated by the former.

But the general public doesn't react well when you run around screaming "Nature is constantly dreaming up better ways to kill us! And the latest creation might hitch a ride out of the forest any day now!" Which leads to some odd pro/con weighing in the public debate.

Re:I’m not convinced by the new lab leak debunking by ThunderSizzle on Saturday March 05, 2022 @10:27PM (#30574766)
Just because the chance of a new pandemic is non-zero doesn't mean we should invite and encourage dangerous behavior that could trigger or quickly spread a strain to the point it turns into a pandemic.

Experimenting with deadly viruses in a major population center is like testing in production if your an AWS or Azure engineer. You might not care too much if it doesn't work, but your screwing over everyone else for your convenience if something does go wrong.

Re:I’m not convinced by the new lab leak debunking by chiefalchemist on Sunday March 06, 2022 @11:00AM (#30578411)
There is risk in doing lab based research. There are clear and obvious ways to mitigate that risk. The science is clear both of these.

Covid was a warning. But scientists are going to ignore that and the science? And we're going to make excuses for that?

What could go wrong?

Re:I’m not convinced by the new lab leak debunking by ethbr0 on Sunday March 06, 2022 @11:59AM (#30578915)
Your response is a bit confusing, so I'm assuming what you mean is that you believe physically isolating high BSL labs in remote areas is a clear and obvious way to mitigate that risk? And that COVID was a warning that we should do more of that? And that scientists are ignoring that warning?

In which case, all of that is predicating on this actually being a lab leak.

But there is no "bury head in sand" option. Eventually something as transmissible and much more lethal is going to spread. At that point, it's too late. The reason SARS-CoV-2 had a vaccine a year later is because of previous work in exactly these sorts of facilities.

BSL labs are the safest places on the planet to work on dangerous pathogens. They aren't perfect. We should continually work to make them more perfect, and fund them to be so. But they're already multiple orders of magnitude more secure biologically than the alternates.

Any country on the planet can work with any dangerous pathogens they can get ahold of. In any way they want. You can only set standards, contribute foreign aid to fund improvement, and try to improve the safety level of the global community.

The "lab leak possibility means we shouldn't do lab research" argument feels like the suggestion that after Nagasaki the world should have abandoned nuclear weapons and ceased research.

In which case, we'd be living under the flag of whichever country ignored that and pursued it anyway.

Re:I’m not convinced by the new lab leak debunking by chiefalchemist on Sunday March 06, 2022 @12:33PM (#30579216)
Put a lab in a densely populated area vs a non densely populated area? I don't see what's confusing about that.
Re:I’m not convinced by the new lab leak debunking by ethbr0 on Sunday March 06, 2022 @04:38PM (#30581511)
It isn't a ceteris paribus comparison, because we don't live in a society where you can force people of expertise to work where you would like them to.

They get to choose.

So you end up with the CDC in Atlanta or Ft. Detrick 50 miles away from Washington, DC. If you said "We're only going to do BSL-4 work at Enewetak," then a lot of work simply wouldn't get done, either because of logistical challenges or because no one wants to relocate there.

And on a personal note, as someone who's lived < 5 miles away from a BSL-4 lab, I slept like a baby. I knew that if the worst happened, from the environment outside the lab or the lab itself, the nearest ICU and associated institutions were staffed by some of the best infectious disease experts on the planet.

Re:I’m not convinced by the new lab leak debunking by taylorius on Sunday March 06, 2022 @06:46AM (#30576877)
Not all pandemics are equal though. Whatever nature might throw at us, might not be as bad as a virus that has been purposefully designed to be deadly and highly contagious, through gain of function research.
Re:I’m not convinced by the new lab leak debunking by sfifs on Saturday March 05, 2022 @08:20PM (#30573976)
One of the important things to keep in mind is that the standards of evidence for safety policy decisions are not the same as those of civil or criminal convictions.

For civil or criminal convictions, the "innocent unless proven guilty" (for various standards of guilty) applies. For safety regulations making, in general "better safe than sorry" is the standard that needs to apply.

Whenever any group feels threatened with regulations that will cause them inconvenience or cost (eg. In this case Move research centers out of urban areas, stricter interpretation of which BSL standards apply to what research - virologists have said on record they were doing a lot of Coronavirus research in levels 2 or 3), there will be push back and an attempt to conflate the standards of civil/criminal conviction (ie. You can't prove X caused Y) with standards of policy making due to self-interest. You see the same sorts of issues with self regulation in the Finance industry, in the aircraft manufacture industry which predictably also led to crises.

Those have to be over-ridden at a soceital level which happened to various degrees after the 2008 crises in Finance and the 737 Max crises in Boeing/FAA.

In other words, in this particular case, whether we can find out what actually happened (very unlikely given so many intersecting conflicts of interest) really doesn't change the key points of what needs to happen going forward.

Re:I’m not convinced by the new lab leak debunking by Flozzin on Saturday March 05, 2022 @08:02PM (#30573856)
I would think, the US or practically any other country would have a huge incentive to be able to blame China for this entire mess. And those incentives would far outweigh having to move a few labs. Plus, "It's China's bad practices that put the world at risk, not the great wonderful lab practices that happen in the US." That would be the line.

There would also be notoriety for the person that would blow the lid off a lab leak. There are plenty of other industries that have eaten there own.

Re:I’m not convinced by the new lab leak debunking by tastyfreeze on Saturday March 05, 2022 @09:23PM (#30574409)
The problem with putting the blame solely on China is that the US funded research at the Wuhan Institute of Virology.

If the lab leak hypothesis proves to be true US research funded by NIH may be the cause.

Re:I’m not convinced by the new lab leak debunking by clearcoat on Saturday March 05, 2022 @08:23PM (#30573996)
I hear this a lot, but I don't understand how people think it's worse. How is a lab leak worse than the virus emerging from a wet market? At least if it's a lab leak it was while doing potentially life-saving medical research.
Re:I’m not convinced by the new lab leak debunking by rnk on Saturday March 05, 2022 @08:38PM (#30574108)
Lab leaks might be able to be avoided, it was human fault, also people really want to blame China so it's kind of wish fullfillment.
Re:I’m not convinced by the new lab leak debunking by Forbo on Saturday March 05, 2022 @08:55PM (#30574225)
Wet markets are able to be avoided as well. Unfortunately people have largely been convinced that perpetual animal genocide is necessary.
Re:I’m not convinced by the new lab leak debunking by clearcoat on Saturday March 05, 2022 @10:01PM (#30574622)
Right, this is what I was thinking. Like with a quick Google for "wet markets" prior to 2019 I see tons of articles warning about the dangers and calling for China to close them:

2007: https://www.reuters.com/article/us-china-foodmarket-idUSHKG2...

2012: https://www.foodsafetynews.com/2012/12/wet-markets-in-china-...

2013: https://qz.com/141596/chinese-bats-carry-viruses-primed-to-c...

2017: https://www.smithsonianmag.com/science-nature/china-ground-z...

I was more aware of this danger and I guess the lab leak theory sounds more like a sci-fi plot to me before the pandemic.

Re:I’m not convinced by the new lab leak debunking by naasking on Sunday March 06, 2022 @12:50PM (#30579366)
> perpetual animal genocide is necessary.

Meat as a staple food is literally not genocide, because an actual animal genocide would literally lead to famine. Making silly comparisons like this doesn't make your position sound reasonable.

Re:I’m not convinced by the new lab leak debunking by Forbo on Sunday March 06, 2022 @02:18PM (#30580238)
Does rephrasing it to "animal war crimes" make it any better?
Re:I’m not convinced by the new lab leak debunking by naasking on Sunday March 06, 2022 @11:19PM (#30584188)
Not at all. What's the war? Do animals even have a concept of war? Don't two parties need to know they're at war for it to qualify as war? Humans aren't killing other animals because animals are a threat to their way of life or their values.

Maybe you want to call meat eating a moral crime, and you can make that argument, but you keep pulling in these tangential human-centric concepts like "war" and "genocide" in an attempt to make the normalized meat diet seem as morally perverse as possible, but I think the hyperbole is doing the opposite. If your position is the rational one, you shouldn't come across as irrational.

Re:I’m not convinced by the new lab leak debunking by Forbo on Monday March 07, 2022 @08:50AM (#30587696)
No, humans are enslaving and torturing multiple species because they taste good. And I'm the irrational one? Because I value not causing suffering over personal pleasure? If that's irrational, then fuck whatever is considered rational. It IS morally reprehensible. Just because they aren't human doesn't mean they don't suffer. If there were a group of humans that were perpetually imprisoned, tortured, and eventually murdered, we would call it what it is: genocide. It fits the definitions laid out by the UN.
Re:I’m not convinced by the new lab leak debunking by blindmute on Sunday March 06, 2022 @12:57AM (#30575373)
Not necessary, but tastes great
Re:I’m not convinced by the new lab leak debunking by Forbo on Sunday March 06, 2022 @12:43PM (#30579301)
When your pleasure is causing suffering, maybe that should be a prompt for self-reflection.
Re:I’m not convinced by the new lab leak debunking by blindmute on Sunday March 06, 2022 @07:37PM (#30582769)
Everyone in the first world causes vast amounts of suffering to humans across the globe just to maintain our standard of living. Just by being on the internet, we've all decided we're okay with this, and won't voluntarily stop causing suffering for our pleasure.

I have reflected upon it, and decided I don't care. Anyway, animals would be the last on the list of things to help if I decided to act truly ethically. It feels nice to pretend you're ethically superior though, posting photos of vegan food with an iPhone, so I won't blame anyone for it.

Re:I’m not convinced by the new lab leak debunking by dragonwriter on Sunday March 06, 2022 @12:56PM (#30579434)
> perpetual animal genocide is necessary.

The argument that there are groups of food animals that constitute peoples in the sense used in the definition of genocide and that destroying them as a people is a necessary instrumental method to meat production is...not obvious.

Re:I’m not convinced by the new lab leak debunking by Izkata on Sunday March 06, 2022 @01:32AM (#30575524)
Given how often it happens, it looks to me more like we've just been lucky so far: https://en.wikipedia.org/wiki/List_of_laboratory_biosecurity...

So with the exception of gain-of-function research, it's not that it's worse exactly, but it's finally put "do we really need to be taking so many risks?" under the spotlight.

Re:I’m not convinced by the new lab leak debunking by sgt101 on Sunday March 06, 2022 @03:15AM (#30575925)
The blame is squarely with the authorities in China.

There was a virus, they knew there was a virus. They held a massive party with the virus, it got out to the world. Then they locked down.

https://www.thestar.com.my/news/regional/2020/02/06/wuhan-ne...

This is the (well documented and well known) event that should be the focus of ire towards the authorities in China.

Re:I’m not convinced by the new lab leak debunking by dmix on Saturday March 05, 2022 @11:26PM (#30575027)
You may be underestimating the hysteria this could generate locally.
Re:I’m not convinced by the new lab leak debunking by stormbrew on Saturday March 05, 2022 @07:55PM (#30573807)
> The political context is a debate about regulating virus labs

This seems... like a naive read of the "political context." It seems like there is far more interest in finding a useful target for blame than any real discussion of how to keep research like that safe, which will likely happen in approximately the same scale whether this WAS a lab leak or not, if only because the specter of it being one has done quite a lot to scare people.

Re:I’m not convinced by the new lab leak debunking by anigbrowl on Saturday March 05, 2022 @09:45PM (#30574536)
> have an incentive to convince the world that it was not their profession, that unleashed this

I think this badly misses the point. Nobody who uncritically promotes lab leak theories is saying 'scientific hubris must be tempered by civic responsibility!' or the like. They'are using it to argue that China launched a bioweapon upon the world, or unscrupulous deep state bureaucrats/freemasons/illuminati did it to cover up the nefarious goings on of this or that politicians etc. etc.

For those people, it's not a medical/scientific ethics & society debate centered around a spirited but civil disagreement between various nerds about the risk calculus. It's a political football thrown about with the goal of breaking as many windows as possible. To ignore this is to consign oneself to the role of a pawn.

Re:I’m not convinced by the new lab leak debunking by trafficante on Sunday March 06, 2022 @01:16AM (#30575457)
Unfortunately, the only folks willing to stick out their necks publicly on this issue are the ones who’re already running around headless. Not sure what fixes this. I can’t imagine anyone reputable with a platform wanting to be the first one to jump into the side of the pool currently filled with schizo posting about how Russia is actually saving the world by blowing up US backed biological weapons labs in Ukraine.

We seem to be sorely lacking in elder statesmen/graybeard type figures who are willing to step into a muddied discourse and create a reasoned discussion from the insanity. There’s obviously a huge demand for such figures (see: the early days of Fauci) but we’re only getting grifters, blatantly political operatives, and those with huge conflicts of interest.

Re:I’m not convinced by the new lab leak debunking by onionisafruit on Saturday March 05, 2022 @11:08PM (#30574948)
If it was a lab leak would you rather keep that on the down low to prevent those people from being proved correct?
Re:I’m not convinced by the new lab leak debunking by anigbrowl on Sunday March 06, 2022 @01:00AM (#30575392)
No of course not. That's why I emphasized uncritically. I'm saying that ignoring the fact of it being such a political football is a fatal mistake, because everything anyone says in public is going to be twisted by people who don't actually GAF about safety policy.
Re:I’m not convinced by the new lab leak debunking by onionisafruit on Sunday March 06, 2022 @10:58AM (#30578393)
You emphasized the word uncritically, but I still missed it on my first reading. Sorry about that.
Re:I’m not convinced by the new lab leak debunking by XorNot on Sunday March 06, 2022 @12:36AM (#30575302)
We should also keep in mind the author is not a disinterested party: the author is a blogger. Not a scientist, not a virologist. They profit from clicks, and you don't get clicks for suggesting that the best available evidence is - surprise - the best available evidence, and will probably turn out to be right.

But since the author will never actually be held to account for being wrong, and certainly isn't putting any money where his mouth is, here we are.

Re:I’m not convinced by the new lab leak debunking by hef19898 on Sunday March 06, 2022 @03:59AM (#30576117)
And he confirmed, in one the forst paragraphs, that he started writting about the lab theory after one of the blogs articles about the press coverage turned into the most read article. I stopped reading when he included a google maps (?) screen shot to show distances as proff of something.
Re:I’m not convinced by the new lab leak debunking by lil_dispaches on Saturday March 05, 2022 @06:23PM (#30573034)
The crux of the problem should be the grave injustice IF it was indeed lab generated and leaked. That is why I refer to it as a Lab Genesis, not a leak. The mere downplaying of the possibility is criminally insane.
Re:I’m not convinced by the new lab leak debunking by rnk on Saturday March 05, 2022 @08:41PM (#30574135)
Downplaying a potential source is a crime? That's silly, that's an over-reaction. You might disagree, but calling it a crime?
Re:I’m not convinced by the new lab leak debunking by ncmncm on Saturday March 05, 2022 @08:10PM (#30573906)
When it is hard enough to engage people on a lab-leak possibility, engaging on lab genesis is way beyond. If a lab leak can be established, then it will be time to consider the actual origin process: lab-propagated natural, or lab-produced. Even then, for lab-produced there are three reasonable alternatives: weaponized, incidental, or wholly accidental.

A weaponized strain would be designed deliberately to be indistinguishable from a natural origin, so there will be no proving that without documents or a confession. An incidental genesis would be an intentional chimera, produced just for research, that got loose. An accidental genesis would be very like a natural origin, but just in lab animals based on strains handled in the lab, maybe even mixed with a natural strain brought in by accident, even incubated unbeknownst in a lab employee.

Personally, I doubt we will ever know more than we do now. All four are possible, all four should be guarded against in the future. But guarding against weaponized viruses is arbitrarily hard. Russia probably still has casks of weaponized smallpox stored underground somewhere. US and China, too, possibly.

Re:I’m not convinced by the new lab leak debunking by lil_dispaches on Saturday March 05, 2022 @08:29PM (#30574042)
Accidental release or not, if they were attempting gain-of-function, which is bio-engineering, and they succeeded, that deserves inquiry. Especially if U.S. leadership, WHO, or NGOs were involved.

To me, the "strength" of the covid-19 is evidence of successful lab experiments, not a fluke contagion. As the pandemic variants showed, natural evolution of viruses tend toward being less lethal. So why did Sars-Cov-2 start overpowered and get weaker?

As viruses can make the jump from one species to another, then it should not be hard to imagine how easy it would be to engineer that same outcome; that is all "gain of function" experiments do: try to emulate a pipeline for viral mutation.

Re:I’m not convinced by the new lab leak debunking by ncmncm on Saturday March 05, 2022 @08:32PM (#30574065)
Evolution of Sars-COV-2 in 2021 was toward more virulent, not less.
Re:I’m not convinced by the new lab leak debunking by lil_dispaches on Saturday March 05, 2022 @08:48PM (#30574168)
Virulence is not the only parameter. Damage caused by the disease is obviously more important. And in that case Sars-Cov-2 is way overpowered compared to previous coronaviruses.

That virulence (contagiousness) is also evidence though. Yes, an airborne respiratory viruses needs to be more contagious than other types, and a more contagious virus needs to be less deadly, or natural selection is going to do its thing (people die before spreading it). Sars-COV-2 was LESS contagious and more deadly than a typical respiratory virus. That is called evidence.

Re:I’m not convinced by the new lab leak debunking by ncmncm on Saturday March 05, 2022 @11:26PM (#30575030)
A more-deadly virus ruins its chances only if it kills before it spreads. In this case, where it appears that COVID-19 is contagious for a week before substantial symptoms appear, and a large fraction of those who catch it are not debilitated, ultimate mortality has little effect.

Smallpox was overwhelmingly more deadly, and its spread was not limited, even without airborne transmission. Measles was also overwhelmingly more deadly, did rely on airborne transmission, and afflicted us century in and century out.

Research into viral function, absent military intent, has no reason to experiment with making the infection more deadly. The primary research goal is to discover what may affect virulence, and try to anticipate and understand what may occur naturally, and then discover ways to block those.

Re:I’m not convinced by the new lab leak debunking by jjeaff on Sunday March 06, 2022 @01:29AM (#30575509)
It's less evidence than you think it is.
Re:I’m not convinced by the new lab leak debunking by xt00 on Saturday March 05, 2022 @07:15PM (#30573456)
Totally agree -- a similar situation has occurred where some airplane crashes and the people that know the most about it either work for the industry or consult for the industry and there is essentially nobody else that knows anything useful. So one way that this type of thing can be approached is to have a commission -- the equivalent of an information "firing squad" -- nobody really knows who said what, but it allows information to be presented from experts. But requires a ton of trust among the people in the commission to not out each other for who said what. I think we can all bet that behind closed doors the people that are involved in this type of research are definitely treating the possibility of a lab-leak as highly probable and are thinking about ways to prevent it in the future since we now know that apparently tons of people would rather get disease X than be told what to do.. so we have a bigger future problem on our hands than we thought if something really nasty escapes..
Re:I’m not convinced by the new lab leak debunking by rossdavidh on Sunday March 06, 2022 @11:39AM (#30578737)
The airplane industry precedent is a good one, but in this case you do have a professional cadre who work on investigating plane crashes, not making planes. This is because there are (or at least were) enough plane crashes to persuade governments to pay for this.

As plane crashes have gotten rarer, the ability of the government (in the US, anyway) to maintain in-house expertise sufficient for the job, has declined, I think not coincidentally. Not sure what the solution is for airlines, but in any case for virus outbreaks we have (fortunately) too few cases to maintain an independent profession of investigators (I hope I am not naive in saying this).

Re:I’m not convinced by the new lab leak debunking by perryizgr8 on Saturday March 05, 2022 @09:55PM (#30574593)
This seems like bs to me. Imagine the investigators of the space shuttle failure or any aeroplane crash behaving like this. After all it reflects badly on the aeronautical engineering profession!

No, it reflects badly on your profession if you don't do your job properly. And I bet most scientists and virologosts understand this.

Re:I’m not convinced by the new lab leak debunking by taylorportman on Saturday March 05, 2022 @09:29PM (#30574449)
The "china" leak has always been a red herring and hopefully people have noticed that the emphasis was always supposed to be gain of function research anyone can do anywhere. The finger pointing aspect is distracting when the real concern is the rapidly evolving underlying technology. The scientists disposition really doesn't matter.. it's not like physicists are responsible for all of the nuclear devices that have been detonated, thousands. Those (and these) scientist's owners will be deciding what their developments will ultimately be used for but in this I don't see that there are any entities capable of leveraging this next wave of "progress" that will be capable of amazing and horrific potentialities.
Re:I’m not convinced by the new lab leak debunking by firasd on Saturday March 05, 2022 @06:42PM (#30573187)
But "more regulation" is in not an intrinsic virtue even though the media/politicians always think they have good ideas on that front. Also the policy question about regulation doesn't mean everyone in the industry will avoid empirical conclusions. Like much of the internet industry is based on ads but that doesn't mean you can't find a programmer to analyze how a particular cookie is set
Re:I’m not convinced by the new lab leak debunking by xbmcuser on Saturday March 05, 2022 @11:28PM (#30575036)
The other side of the problem is that humans do not want to admit that they are afraid of death and change. Blaming lab leak for the pandemic gives them the feeling of control and safety. They would rather have the belief that this was human caused rather than natural as they cant control a natural disaster.
Re:I’m not convinced by the new lab leak debunking by jjeaff on Sunday March 06, 2022 @01:36AM (#30575537)
Ya, it's the same thing behind a lot of conspiracy theories. 911 was an inside job because people don't want to accept that a small contingent of lightly funded terrorists could pull off something so devastating. Or that mass shootings are staged because people don't want to believe that someone could be so murderous.
Re:I’m not convinced by the new lab leak debunking by rossdavidh on Monday March 07, 2022 @11:35AM (#30589865)
Good point.
Re:I’m not convinced by the new lab leak debunking by morelisp on Saturday March 05, 2022 @06:19PM (#30572996)
As opposed to journalists, who would never keep an exciting story running despite weak evidence.
Re:I’m not convinced by the new lab leak debunking by FabHK on Saturday March 05, 2022 @06:38PM (#30573153)
No, just like journalists. You're demolishing a straw man.
Re:I’m not convinced by the new lab leak debunking by Wevah on Saturday March 05, 2022 @07:47PM (#30573740)
I thought the comment was sarcastic.
Re:I’m not convinced by the new lab leak debunking by morelisp on Sunday March 06, 2022 @02:16AM (#30575684)
I would never write a sarcastic comment on this noble forum.
Re:I’m not convinced by the new lab leak debunking by mprime1 on Sunday March 06, 2022 @12:32PM (#30579202)
By the same logic there should be no software engineers speaking up about the dangers of social media or aggressive user tracking.

Is that the case?

Re:I’m not convinced by the new lab leak debunking by rossdavidh on Monday March 07, 2022 @11:34AM (#30589850)
Well there isn't currently any plausible threat of restricting the ability of a small group of developers to make their own software, without government oversight. If we had a piece of malware that killed a bunch of people and brought the economy to a screeching halt worldwide, there probably would be calls to restrict individual developers from making whatever software they want, and the situation would feel quite different.
Re:I’m not convinced by the new lab leak debunking by FredPret on Sunday March 06, 2022 @10:33AM (#30578195)
I know nothing about virology, so I have this question: why do it? What is the loss if we shut down all virology?

They do gain of function research, breeding deadlier viruses, and then what? Do they use this to pre-develop vaccines?

Re:I’m not convinced by the new lab leak debunking by rossdavidh on Sunday March 06, 2022 @11:43AM (#30578768)
One use is to have understanding of how viruses work, so that you can accurately predict spread. If we assume that SARS and MERS (both coronaviruses that seem nearly certain _not_ to have been made in labs) required a knowledge of how coronaviruses work, then a lab doing the general kind of work that was done in Wuhan is real.

For example, we already knew that the spike protein was critical in reproduction of the covid-19 virus, whereas we might not have known as much about that if we had no virology labs (I'm not an expert in the field, I might be wrong here).

But, for any particular line of research, your question is still a valid one. Is this particular research likely to have a payoff worth the (inevitably non-zero) risk? The issue is how (and who) to make that decision.

Re:I’m not convinced by the new lab leak debunking by 908B64B197 on Saturday March 05, 2022 @07:21PM (#30573506)
How many of them were either financed by Chinese programs such as the Thousand Talent Plan [0], or one of their students or advisors or department?

Can they all claim, and prove, to be free of foreign influences and allegiance?

[0] https://en.wikipedia.org/wiki/Thousand_Talents_Plan