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Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by Wowfunhappy on Saturday March 21, 2020 @07:25AM (#22645823)
But how much of the US’s growth is due to us finally having some (albeit not enough) testing?
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by simonh on Saturday March 21, 2020 @07:44AM (#22645883)
This is key. We really can't compare countries confirmed case numbers directly because they are operating very different testing programmes. Just look at Germany. More confirmed cases than the USA, but a quarter of the deaths. Germany also has 80% as many cases as Spain, but about 5% as many deaths. All that, without a severe lockdown.

Clearly something completely different is going on there than in many other countries, and it seems they have an extremely effective and well organised testing system. They're testing about 160,000 people a week. In comparison, the UK to date has only tested around 50,000 people in total so no wonder our case numbers are far lower, even though we have double the number of deaths.

So Germany is an outlier, but it just goes to show even for other countries you can't just compare the curves and draw any definitive conclusions without also looking at the testing regime. This is where the experts with their detailed population models and simulation tools come in.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by kire2345 on Saturday March 21, 2020 @08:05AM (#22645967)
I think what is going on is a combination of relatively good testing capacity from the beginning and mostly young people infected, which due to the testing were prevented from spreading it to older demographics. See https://experience.arcgis.com/experience/478220a4c454480e823...

Also there is the purely anecdotal hypothesis of a cultural difference between for example Italy, Spain and Germany. In the southern countries it seems like older people have quite an active social life compared to Germany.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by sveme on Saturday March 21, 2020 @08:23AM (#22646058)
There are also far more old people living with young people in Italy and Spain than in Germany.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by vinniejames on Saturday March 21, 2020 @07:59AM (#22645939)
We could possibly clean up the numbers, assuming the death rate is predictable across regions.

Take numbers from a region where testing is frequent, say the death rate is 2%. Then scale the numbers in a region with lack of testing to match the 2% death rate.

Not perfect, as there are external factors like hospital capacity/quality and existing population health.

However, it should give a closer approximation of total cases where politicians fail to provide adequate testing.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by qaq on Saturday March 21, 2020 @08:07AM (#22645983)
Well unfortunately US has much higher rate of obesity, diabetes and other factors that will increase mortality so would be pretty hard.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by vinniejames on Saturday March 21, 2020 @08:11AM (#22646001)
China has a much higher rate of smokers, poor air quality, and existing respiratory disease.

Do you have any statistics pointing to obesity as an increased risk factor for a respritory disease?

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by qaq on Saturday March 21, 2020 @08:21AM (#22646050)
High Blood pressure was a big factor from what I read. There is very strong correlation between obesity and hypertension.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by fragmede on Saturday March 21, 2020 @12:02PM (#22647431)
Each country has it's own date for when "testing came online", and it seems like starting from then might make things more comparable, despite differences in testing capacity and strategy. Another approach might be to on start looking at the data after the number of cases is > 100.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by rasz on Saturday March 21, 2020 @11:01AM (#22646942)
Stop repeating German propaganda :(

https://www.youtube.com/watch?v=0M4kbPDHGR0&feature=youtu.be... turn on google auto translate

TLDR: Any comorbidities present at the time of death are reported as the main culprit. In other news https://www.thelancet.com/action/showPdf?pii=S0140-6736(20)3... Table 2: Treatments and outcomes. Sepsis 100%, Respiratory failure 98%. There you go, nobody dies from the virus alone, problem solved, 20x less deaths than comparable Spain.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by detaro on Saturday March 21, 2020 @11:05AM (#22646971)
Then why are basically all Corona deaths in Germany reported as having other illnesses too? If this claim were true, none of these deaths of sick old people would have been reported as being due to Corona. Do you have any evidence this is more than speculation (at least the english translation also makes it sound like it is worded speculation, not a claim of fact), and that someone who was known to be infected and died was not reported?

I keep asking people about this because I'd for sure would like to know if it were happening, but the only two sources I've seen sounded like speculation by Italian officials that at least as absolute as it is reported in other languages does not match the actual reporting here as far as I can tell.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by hallohallohallo on Saturday March 21, 2020 @07:54AM (#22645925)
It is the health care system like number of ICUs, training of doctors and stuff like not being able to get antibiotics simply over the counter like in Italy. If my memory serves me right e.g. in Italy 29% have a resistance to antibiotics, in Germany only 0.4%.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by simonh on Saturday March 21, 2020 @07:58AM (#22645934)
People don't become resistant to antibiotics, bacteria do and resistant bacteria in Italy would just spread to Germany. Anyway Covid-19 is a virus, not a bacterium.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by guiriduro on Saturday March 21, 2020 @08:09AM (#22645994)
While its true SARS-CoV-2 is a virus, opportunistic bacterial pneumonia is a secondary complication of Covid19 which increases its lethality. So you need decent antibiotics too.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by radicalbyte on Saturday March 21, 2020 @09:09AM (#22646256)
..and it's nasty, my wife only just recovered from it a week ago after a total of 8 weeks in bed.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by emmelaich on Saturday March 21, 2020 @08:01AM (#22645946)
Related, there's also the distinct possibility that many had Covid-19 well before it was in public consciousness.

Look for ILI (Influenza-like Illness) stats which were appreciably higher in January. The obvious inference is that many had Covid-19 before it was recognised as such.

This might be a good thing.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by nemo44x on Saturday March 21, 2020 @08:21AM (#22646049)
I think this is underrated. This thing must have been spreading since November here.

I know a person who back in January acquired something like pneumonia and a bad fever, went to the hospital for awhile and tests were negative for flu, etc. doctors just didn’t know what it was. The person has COPD however.

But anecdotally I’ve noticed quite a few more colleagues over the last few months out sick “with the flu or something”. No idea.

They’re still only testing people with symptoms. We need a randomizes test and a test for antibodies to have any idea how much it has already spread.

If it’s as contagious as they say and spreads in asymptotic people then why wouldn’t there be a significant population that has acquired and recovered from this? Many probably with very mild symptoms.

I could just be in denial right now as well.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by magicsmoke on Saturday March 21, 2020 @09:31AM (#22646360)
If COVID19 was spreading in the US since November then the US hospital system should have been overwhelmed by now with intensive care patients. The first infection in China was traced back to November and they were building hospitals by early February.

The only places I've seen the first US infection being dated that early are conspiracies on Chinese social media that claim the origin of COVID19 to be the US instead of Wuhan. The only way that theory works is to date the first infection in the US and claim that Americans bought it into China during the Wuhan Military games. That theory is easy enough to debunk with common sense because if the US had COVID first the hospitals would be completed overwhelmed before China's was, but it's not the first time wishful thinking's buried common sense in Chinese history.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by fragmede on Saturday March 21, 2020 @12:07PM (#22647477)
"spreading in the US since November", and "there's a new, highly infectious respiratory disease since November" are two very different things.

I don't know anyone that credibly believes it was in the US in November. We did, however, that something was amiss that early, and if the US had a pandemic response team who's job was to see something like this coming, we could have been getting testing ready since then.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by irq11 on Saturday March 21, 2020 @11:27AM (#22647166)
”If COVID19 was spreading in the US since November then the US hospital system should have been overwhelmed by now with intensive care patients.”

Or the fatality and hospitalization rates have been overestimated due to severity bias.

We know this to be true, actually. We just don’t have good estimates of what the true rates are.

It wouldn’t be shocking at all to find out the virus is already widespread, and only slightly more dangerous than influenza.

Even in Italy, if there is widespread infection, the ~4k dead would reflect a low mortality rate.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by watwut on Saturday March 21, 2020 @06:07PM (#22650622)
It would be shocking to epidemiologists. All their confidence intervals are well above influenza. They are fully aware of all caveats amateur people talk about here and don't think it is like normal flu.

In italy in hard hit city, they were unable to cremate people fast enough and army had to move bodies. Influenza does not cause that.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by irq11 on Saturday March 21, 2020 @11:02PM (#22652333)
Everything I said above was directly taken from non-amateur epidemiologists. I have invented nothing.

The error bars on CFR estimates run from fractions of a percent to a few percent. In countries that have tested large numbers of people who are not severely ill, the case fatality rates have been at the low end of that range.

This isn’t “shocking to epidemiologists”, it’s shocking only to people who dismiss basic facts and try to use irrelevant distractions (like cremation rates) to incite fear.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by watwut on Sunday March 22, 2020 @07:59AM (#22654333)
Epidemiologists say that influenza is easier to control. Irrelevant distraction relevant to topic says that only school here and there has to be closed to contain it. Epidemiologists say on that that one infected person with influenza infects less people then one infected with corona.

Epidemiologists do count with overwhelmed hospitals and services, excess deaths due that that, excess deaths on unrelated heath problems. It not just something they talk about, they have it in their models too. This does not happen with influenza, because it is easier to control. Irrelevant distraction there is Italy or Spain lately.

Epidemiologists do talk also about costs after epidemic ends, in treatment of people who will need care for long.

What amateurs do is to ignore all the above, pick up case fatality ration in well run non-overwhelmed health care system and pretend that is situation same as influenza to feel good.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by irq11 on Monday March 23, 2020 @08:26PM (#22670467)
” Epidemiologists say that influenza is easier to control.”

Not that I have heard of. You’re going to have to cite some evidence here.

(They’re both respiratory viruses with similar R0, so your evidence needs to be pretty extraordinary to be convincing.)

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by gvjddbnvdrbv on Saturday March 21, 2020 @04:17PM (#22649654)
21 days to death, doubles every 2.5 days, exponential growth. Do the maths.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by mrfusion on Saturday March 21, 2020 @10:17AM (#22646634)
You’d think mild cases wouldn’t have the same viral load as the severe cases. Even if you’re technology contagious it may be less for the mild cases.

Especially asymtomatic. You’d not be coughing or sneezing more than usual which must have some effect.

Just a thought. No one seems to have mentioned this idea.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by mynegation on Saturday March 21, 2020 @11:30AM (#22647195)
What is this idea exactly? That the virus rolled through Seattle and other areas with just a bunch of relatively mild cases and without a critical uptick in hospital load? I am not an epidemiologist but that does not seem realistic.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by fma on Saturday March 21, 2020 @09:20AM (#22646301)
If you haven't heard about the Seattle Flu Study - this is a great read. Coronavirus was in Seattle before officials confirmed it. The federal government also prevented the researchers from doing more testing, delaying valuable time.

https://www.nytimes.com/2020/03/10/us/coronavirus-testing-de...

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by acqq on Saturday March 21, 2020 @08:34AM (#22646109)
> If it’s as contagious as they say and spreads in asymptotic people then why wouldn’t there be a significant population that has acquired and recovered from this?

Because all the effects are limited by the time it takes for them to happen. We know the speed of growth, it's much faster than the expected recovery times. From all known COVID-19 cases the number of recovered are still dominated by the recovered in China.

   China: reported cases: 81,008
          dead:       3,255 
          recovered: 71,740

   Whole world: reported cases: 282,395
                dead:      11,822
                recovered: 93,189
Virus causing COVID-19 is "novel" meaning not existing among humans at all until a few months ago.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by mrfusion on Saturday March 21, 2020 @10:12AM (#22646594)
Seems like everyone I talk to either had something like that or knows people who did. It could be a huge effect.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by devmunchies on Saturday March 21, 2020 @10:03AM (#22646528)
> a person who back in January acquired something like pneumonia and a bad fever, went to the hospital for awhile and tests were negative for flu

That’s exactly what happened to my dad in February.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by gvjddbnvdrbv on Saturday March 21, 2020 @04:15PM (#22649640)
Yes it was the case for many people in February. They didn't have covid. Your dad is very high risk and should stay home. The doctors in UK don't need a test to diagnose covid in a patient with pneumonia. They see it in a second on an xray because it is so distinct. The Chinese doctors said the same. So do the Italians.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by gvjddbnvdrbv on Saturday March 21, 2020 @09:16AM (#22646286)
You are in denial.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by simonh on Saturday March 21, 2020 @08:16AM (#22646031)
If that were true, we should see a much higher proportion of tested people showing positive. Also we shouldn't see the proportion of people tested being positive shooting up, but we do. Those ILI stats were probably just Flu.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by mrfusion on Saturday March 21, 2020 @10:11AM (#22646587)
I believe that most of the current testing only shows active infections?
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by simonh on Saturday March 21, 2020 @10:47AM (#22646823)
Yes, and it has shown initially small numbers of active infections, growing rapidly, as a proportion of those tested. If the virus was already widely distributed, we would expect it to be much closer to equilibrium.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by xienze on Saturday March 21, 2020 @08:47AM (#22646160)
Yeah I’m not sure what people are expecting to happen here. This virus has been circulating in the US for months and testing was limited. There’s surely many multiples of infected people than currently reported, and that’s true for any country that isn’t doing blanket testing of entire population.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by mynegation on Saturday March 21, 2020 @11:38AM (#22647254)
Even if that (EDIT: ‘that’ being an idea that virus has been circulating for months) were true (which almost certainly it is not), so what? The only logical explanation for this is that percentage of severe cases relative to totally susceptible and infected is orders of magnitude lower, and now the total number of infected is so large that number of severe cases is starting to get noticeable. But that is not the picture we are getting from South Korea that had much more comprehensive testinG.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by xienze on Saturday March 21, 2020 @11:47AM (#22647326)
> Even if that were true (which almost certainly it is not)

What are you referring to? You don’t think the virus is already much more widespread in the US than currently reported numbers? I’m just making the observation that perhaps the large increases in US cases are more indicative of confirmation of already existing cases rather than necessarily being _new_ cases.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by mynegation on Saturday March 21, 2020 @11:55AM (#22647381)
I am not arguing that virus is more widespread than the reported numbers, that much is obvious. I was replying to the idea that virus has been circulating “for months” undetected. With a doubling time of 5 days or so, with “for months” circulation we would be in a totally different territory right now.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by xienze on Saturday March 21, 2020 @12:45PM (#22647785)
> I was replying to the idea that virus has been circulating “for months” undetected.

I don’t think that’s crazy at all. We had our first case sometime in January, and only until very very recently have we had any significant travel restrictions. It’s very contagious and for a significant number of people there are no real symptoms, or if there are, nothing life threatening. I don’t think it’s crazy at all that it’s been working it’s way around the US population for months.

Maybe to put it another way, if we could instantly test al 300+M Americans right this instant, would you be surprised if say 20M or so tested positive or had had it?

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by mynegation on Saturday March 21, 2020 @01:19PM (#22648048)
> would you be surprised

Yes, I would be very surprised. Given what we know about severity distribution that means 2M hospitalizations and ~200K-1M ICU cases that we somehow missed.

Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by tyingq on Saturday March 21, 2020 @07:41AM (#22645873)
That's a very good point, and the lack of tests had a secondary effect. Nobody here took it very seriously at first, because the numbers were very low.
Re:The Doctor Who Helped Defeat Smallpox Explains What's Coming by throwaway_pdp09 on Saturday March 21, 2020 @07:38AM (#22645865)
Good question, I don't know. If it helps, a quick search got this https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/test...

See table at bottom.