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Re:After decades, FDA moves to pull ineffective decongestant... by kens on Thursday November 07, 2024 @10:59PM (#42084008)
One of my favorite papers is "A simple and convenient synthesis of pseudoephedrine from N-methylamphetamine" [1].

This is a satirical paper. Because pseudoephedrine (i.e. the good decongestant) is very difficult to obtain due to restrictions, but "N-methylamphetamine can be procured at almost any time on short notice", the paper describes how to synthesize pseudoephedrine from meth with a procedure that looks valid.

[1] https://improbable.com/airchives/paperair/volume19/v19i3/Pse...

Re:After decades, FDA moves to pull ineffective decongestant... by hansvm on Thursday November 07, 2024 @11:17PM (#42084088)
I found out recently that you don't just need a decent government ID; it needs to be from the state you're purchasing the Sudafed from, because apparently each state administers its own database. If you run out and have a persistent cough (weakened immune system from not licking doorknobs the last few years of covid, or so do the doctor says) from a common cold while on vacation, you're shit out of luck unless you go back home or you and an accomplice are willing to procure your cough medicine with their license.
Re:After decades, FDA moves to pull ineffective decongestant... by Gibbon1 on Friday November 08, 2024 @12:03AM (#42084320)
My WAT.

Refused sale of Sudafed because my license was expired. Apparently I accidentally tossed my new license and kept the old one. Doh! However they happily refilled my schedule III meds with the expired license.

As I said WAT.

Re:After decades, FDA moves to pull ineffective decongestant... by randrus on Thursday November 07, 2024 @11:32PM (#42084150)
Seems like it varies by state - I’ve purchased Sudafed in at least two states other than my own.
Re:After decades, FDA moves to pull ineffective decongestant... by numbsafari on Thursday November 07, 2024 @11:40PM (#42084199)
Same here.
Re:After decades, FDA moves to pull ineffective decongestant... by schmidtleonard on Thursday November 07, 2024 @11:58PM (#42084300)
Me too.
Re:After decades, FDA moves to pull ineffective decongestant... by nfw2 on Friday November 08, 2024 @12:23AM (#42084402)
It's ironic that the pharmacies are so paranoid that you'll cook meth from Sudafed but are happy to enable amphetamine habits in kids that have trouble focusing in school.
Re:After decades, FDA moves to pull ineffective decongestant... by EdwardDiego on Friday November 08, 2024 @12:35AM (#42084450)
Adderall is a 3:1 dextroamphetamine/levoamphetamine mix.

Methamphetamine is a whole other level of stimulant.

> amphetamine habits in kids that have trouble focusing in school.

1) Do you have evidence that Adderall at therapeutic dosages is anywhere near as addictive as methamphetamine at recreational dosages?

2) Yeah, ADHD makes it real hard to focus at school. I never graduated from high school, and I dropped out of university as an adult student without even completing one year, thanks to untreated ADHD. Not to mention the impulsive behaviour, the inability to stick at boring things etc. etc. It's not great in our society.

You're implicitly minimising the very real impact of ADHD, that's not super great.

In fact, one of the biggest issues for people finally being treated for ADHD as adults is the grieving process around "What my life could've been if my parents hadn't believed that ADHD wasn't real and my issues in school and my 'disruptiveness' was solely due to 'food intolerances', because my Mom read a magazine article about it once, then paid a quack to stick a probe in my ear, one on my finger, and then rub food on my skin while looking at a galvanometer making 'hmmm' noises sagely."

3) You know there's been Adderall shortages in the USA recently due to DEA manufacturing limitations right? So it's not like they're just throwing out to kids like it's a lolly scramble.

Anyway, it's about as ironic as 10,000 spoons when all you need a knife. That is, not at all.

Re:After decades, FDA moves to pull ineffective decongestant... by culi on Friday November 08, 2024 @01:11AM (#42084591)
> Methamphetamine is a whole other level of stimulant.

The extra methyl group that differentiates it from regular amphetamine salts mainly serves the purpose of crossing the blood-brain barrier quicker. However, during this process it loses that extra methyl group. So whether you're taking meth or adderal, the chemical that actually reaches your brain is ultimately the same

In fact, methamphetamine is available as a prescription ADHD medicine under the brand name "Desoxyn"

Re:After decades, FDA moves to pull ineffective decongestant... by InDubioProRubio on Friday November 08, 2024 @03:12AM (#42085184)
And you get a erdös number for taking them : https://en.wikipedia.org/wiki/Paul_Erd%C5%91s#Personality
Re:After decades, FDA moves to pull ineffective decongestant... by neonnoodle on Friday November 08, 2024 @07:18AM (#42086280)
Don’t forget to use the tweaking umlauts:ő
Re:After decades, FDA moves to pull ineffective decongestant... by jart on Friday November 08, 2024 @01:16AM (#42084621)
I thought that (1) meth (e.g. methylphenidate a.k.a. ritalin) blocks reuptake of dopamine, and (2) amphetamine (e.g. dextroamphetamine) stimulates production of dopamine, and (3) methamphetamine (a.k.a. desoxyn) does both. Is that understanding accurate?
Re:After decades, FDA moves to pull ineffective decongestant... by LM358 on Friday November 08, 2024 @03:05AM (#42085146)
I have never seen "meth" taken to mean anything other than methamphetamine, and certainly not methylphenidate.
Re:After decades, FDA moves to pull ineffective decongestant... by bichiliad on Friday November 08, 2024 @03:57AM (#42085402)
“Meth” is methamphetamine, not methylphenidate. Ritalin isn’t the same thing as Meth. Not sure about how Ritalin vs Adderall act different on dopamine.
Re:After decades, FDA moves to pull ineffective decongestant... by jart on Friday November 08, 2024 @06:45AM (#42086075)
Then why does it have meth in the name genius?
Re:After decades, FDA moves to pull ineffective decongestant... by 542354234235 on Friday November 08, 2024 @08:28AM (#42086687)
“Don’t call me a homo sapien! I’m not gay!”
Re:After decades, FDA moves to pull ineffective decongestant... by jart on Friday November 08, 2024 @08:44AM (#42086773)
Leave it to the peanut gallery to always assume the vulgar definition.
Re:After decades, FDA moves to pull ineffective decongestant... by EdwardDiego on Friday November 08, 2024 @09:04AM (#42086931)
<spiderman J Jonah Jameson meme> You're kidding, right? </spidey-meme>
Re:After decades, FDA moves to pull ineffective decongestant... by EdwardDiego on Friday November 08, 2024 @01:13AM (#42084598)
Yeah, precisely, that methyl group is why methamphetamine is super popular, it makes a whole lot of difference in the felt effect.
Re:After decades, FDA moves to pull ineffective decongestant... by NBJack on Friday November 08, 2024 @12:42AM (#42084483)
I think the parent post is more likely alluding to the abuse of the medication, particularly in higher learning institutions.

https://psych.wisc.edu/news/easy-access-pressure-on-students....

Aderrall is a Schedule II drug. This is the same category as oxycodone and fentanyl.

https://www.therecoveryvillage.com/adderall-addiction/adhd-a...

Re:After decades, FDA moves to pull ineffective decongestant... by EdwardDiego on Friday November 08, 2024 @12:57AM (#42084547)
~~Pharmacists have no ability* to not dispense medicines if a doctor prescribes them.~~

_Edit: I am told I'm wrong on this front, and I stand corrected_

The fact that doctors are prescribing them too freely is definitely worth looking into.

But severely restricting medication that is used to effectively treat disease because it has abuse potential only harms legitimate users. But definitely worth auditing prescriptions to ensure that they're being issued for valid diagnoses.

But as for illegitimate users? You ban it, they'll find something else.

And as someone who needs ADHD meds to do things like "remember I have a todo list, remember where I left it, and remember to use it", I very much resent the people who abuse the meds I need to function in our society to pass their law degrees easier.

I resent the meth addicts who try to get an ADHD diagnosis for their kids so they can abuse (or sell...) their children's ADHD meds when they can't afford meth, because it means I have to pee into a jar every three months to prove I'm not a meth addict who is abusing methylphenidate.

(My country uses methylphenidate / Ritalin / Concerta (the slow release form) as the first treatment for ADHD, Adderall is not prescribed here that much, if ever, but it is possible to be prescribed dexamphetamine if you're bad enough).

But I really do object to glibly implying that every child who is prescribed a treatment for ADHD is actually a case of pharmacists gleefully overmedicating, it's naïve, unsympathetic, and, tbh, rather unfair to pharmacists.

As for what schedule a drug is... ...is the harm of Adderall abuse the same as the harm of fentanyl abuse?

Drug schedules aren't a good way to determine harm, IMO. They're a good way to discern moral panics though.

E.g., in my country, Class A, the drugs that attract the highest penalties, include magic mushrooms, mescaline, DMT, and that one you get from licking toads, bufotentine or something, alongside classics like heroin and cocaine.

Fentanyl is Class B, alongside opium, morphine, amphetamine, methylphenidate, MDMA, and one that always amuses me, hashish.

* There's probably some dumb-ass rules around declining to dispense abortifacients because of religious beliefs, I'm sure.

Re:After decades, FDA moves to pull ineffective decongestant... by jclulow on Friday November 08, 2024 @03:19AM (#42085221)
> I very much resent the people who abuse the meds I need to function ... I resent the meth addicts ... it means I have to pee into a jar every three months to prove I'm not a meth addict who is abusing methylphenidate.

It's important to remember that no addict did this to you. An addict doesn't force Kaiser to charge me $20 when they demand I piss in a cup in order to receive my legally prescribed medication. It's fucking Kaiser, and the DEA, and the mad cap conservative politicians and their shitty fucking values. Drug addicts are suffering from a health problem, just like you and I are with our ADHD. None of us have the power to influence the massive engine of carceral drug policy and the promotion of mass moral panic about people taking medication that helps them.

It's important to point the anger at the right people.

Re:After decades, FDA moves to pull ineffective decongestant... by jimmaswell on Friday November 08, 2024 @03:32AM (#42085280)
Using telemedicine in New Hampshire, I don't have to take any drug tests for mine, just self-report my blood pressure and pulse on zoom every 3 months.
Re:After decades, FDA moves to pull ineffective decongestant... by EdwardDiego on Thursday November 14, 2024 @04:33AM (#42134487)
Fair point. Thank you for the feedback :)
Re:After decades, FDA moves to pull ineffective decongestant... by cyberax on Friday November 08, 2024 @01:28AM (#42084671)
> ~~Pharmacists have no ability* to not dispense medicines if a doctor prescribes them.~~

As others said, it's not true. Pharmacists are also trained to spot any possible adverse drug interactions with other medications that you might be taking.

It more often happens in the clinical setting, rather than at retail pharmacies, but it still is a possibility.

Re:After decades, FDA moves to pull ineffective decongestant... by EdwardDiego on Friday November 08, 2024 @02:02AM (#42084836)
I do believe you quoted my edit after being corrected :)

I was definitely wrong.

Re:After decades, FDA moves to pull ineffective decongestant... by refurb on Friday November 08, 2024 @01:04AM (#42084573)
> Pharmacists have no ability* to not dispense medicines if a doctor prescribes them.

This is not true. Pharmacists have the right to not fill a prescription for a number of reasons, and in fact can be held liable for not doing so.

If they feel the use of the drug is medically inappropriate they can decide not to fill it. If they feel the patient is taking it for a non-medical reason (abuse) they can choose not to fill it.

Pharmacists are medical professionals who are expected to use their judgement to make sure medicines are not used inappropriately.

Re:After decades, FDA moves to pull ineffective decongestant... by EdwardDiego on Friday November 08, 2024 @01:11AM (#42084593)
Interesting, do you have any material I can read up on about this?

P.S., have edited that statement after your correction, much obliged :)

Re:After decades, FDA moves to pull ineffective decongestant... by AnthonyMouse on Friday November 08, 2024 @03:11AM (#42085176)
> I think the parent post is more likely alluding to the abuse of the medication, particularly in higher learning institutions.

It's kind of weird that people are calling this "abuse" when it's apparently using the drug in the same context and dosage as it's prescribed therapeutically, plausibly by people who actually have ADHD but don't have the time or insurance to get a prescription.

It's an interesting case study in what would happen if it was more widely available in a pharmaceutical form with a known dose and purity. What percentage of these college students are actually getting addicted to amphetamine vs. just taking a therapeutic dose here and there?

Re:After decades, FDA moves to pull ineffective decongestant... by renewiltord on Friday November 08, 2024 @02:11AM (#42084874)
Damn, if Schedule II drugs are that bad, Schedule I drugs must be terrible. Let me go see:

> Some examples of Schedule I drugs are: lysergic acid diethylamide (LSD), marijuana (cannabis)

Oh damn, marijuana is worse than this drug? I hope they arrest anyone selling marijuana. What’s that you say? Legal? In California? Oh, in lots of states?

Re:After decades, FDA moves to pull ineffective decongestant... by BenjiWiebe on Saturday November 09, 2024 @01:56PM (#42096160)
Schedule I "merely" means: The drug or other substance has a high potential for abuse. The drug or other substance has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug or other substance under medical supervision.
Re:After decades, FDA moves to pull ineffective decongestant... by whythre on Friday November 08, 2024 @12:37AM (#42084460)
I don’t know why you are being downvoted, adhd medication is insanely overprescribed. Turns out, kids get antsy and hard to control after cramming them into overcrowded rooms for 8-9 hours a day doing slop work. Some schools are now forgoing any form of recess at all. Modern public education is inhuman and dystopian.
Re:After decades, FDA moves to pull ineffective decongestant... by epistasis on Friday November 08, 2024 @12:48AM (#42084506)
It is absolutely not the job of a pharmacist to make decisions about which drugs are being overprescribed, and IMHO it's a dangerous thing to suggest. The pharmacist should assess for drug interactions, but we can't burden pharmacists with knowing the details that went into a prescription, and we shouldn't have them second guessing the diagnosis of a doctor. Down that road lies madness.
Re:After decades, FDA moves to pull ineffective decongestant... by culi on Friday November 08, 2024 @01:15AM (#42084613)
I get where you're coming from but pharmacists have the right to refuse to fill a prescription and in fact can be held liable for not doing so. Pharmacists are trained medical professionals and are expected to use their judgement
Re:After decades, FDA moves to pull ineffective decongestant... by _moof on Friday November 08, 2024 @02:25AM (#42084951)
Judgment based on what? The five-second interaction we have while they're doing twenty other things thirty feet away?
Re:After decades, FDA moves to pull ineffective decongestant... by TeMPOraL on Friday November 08, 2024 @03:19AM (#42085222)
Another thing is, do you get an actual trained and knowledgeable pharmacist, or a technician?

In Poland, pharmacies are required by law to have a MSc in pharmacy present during operating hours - that is, no less than one pharmacist with a Masters degree. One is enough. Which means that's all you get. You may not even see them unless you're buying ADHD meds, which need MSc to sign off on them. Otherwise, you're almost always dealing with a pharmacy technician. Some are pretty knowledgeable[0], others could be replaced by GPT-3.5[1] with net benefit to the customer. The latter type, if they're going to notice anything about you, it's whether you're likely to buy some useless supplement or homeopathic product.

--

[0] - Probably on their way to MSc in Pharmacy, which is a mistake if they're looking for a pharmacy job - pharmacies don't want people with MSc, there's enough of them around already; they want the cheap technician labor.

[1] - Yes, not even 4.

Re:After decades, FDA moves to pull ineffective decongestant... by epistasis on Friday November 08, 2024 @04:27PM (#42090607)
It's one thing to use their judgement to refuse somebody who is going to get a bad drug interaction, and another for a pharmacist to say "I've given out too many of X prescriptions, I'm going to start cutting off people from their prescription based on my judgement of them," and this latter one is what was under discussion and the one that I'm rejecting.
Re:After decades, FDA moves to pull ineffective decongestant... by nfw2 on Friday November 08, 2024 @08:01AM (#42086521)
I agree it was a poor choice of words as the decisions are largely being made by regulators and doctors.
Re:After decades, FDA moves to pull ineffective decongestant... by _moof on Friday November 08, 2024 @02:23AM (#42084943)
Oh good, another round of "ADHD isn't real."
Re:After decades, FDA moves to pull ineffective decongestant... by arcticbull on Friday November 08, 2024 @02:42AM (#42085032)
The more interesting take for me is that these meds work roughly the same way and almost as well in people without ADHD (a symptom cluster, not a single disease per se, like everything else in the DSM). As we give them to people with ADHD why not let anyone get a scrip?
Re:After decades, FDA moves to pull ineffective decongestant... by Llamamoe on Friday November 08, 2024 @03:02AM (#42085121)
People without ADHD already get more than enough benefit from just coffee. Stimulants might be able to benefit them further, but if you let anyone take them, eventually it'd become expected of everyone due to their increased productivity, and the potential consequences of abuse are much higher than coffee.
Re:After decades, FDA moves to pull ineffective decongestant... by arcticbull on Friday November 08, 2024 @03:38AM (#42085311)
Chronic use of caffeine blunts the effects, it doesn't do much to regular drinkers. You develop tolerance very quickly. I can drink several cups and get basically no effect. Apparently your body just increases the quantity of adenosine receptors in the brain to offset the caffeine.
Re:After decades, FDA moves to pull ineffective decongestant... by atemerev on Friday November 08, 2024 @04:29AM (#42085549)
Well, I yet to see someone without ADHD who becomes calmer and slows down after taking stimulants.
Re:After decades, FDA moves to pull ineffective decongestant... by nfw2 on Friday November 08, 2024 @07:59AM (#42086508)
I didn't say it's not real. A doctor prescribed me Adderall at 18 after talking to me for 5 minutes because I was having trouble sleeping. It did more harm than good.

Something can have therapeutic uses and still be over-prescribed.

Re:After decades, FDA moves to pull ineffective decongestant... by pdonis on Friday November 08, 2024 @12:41AM (#42084481)
> you don't just need a decent government ID; it needs to be from the state you're purchasing the Sudafed from

The FDA rule on this [1] doesn't appear to be quite that strict: it says the ID can be "a photo identification card issued by the State or the Federal Government or a document that is considered acceptable by the seller". It doesn't explicitly say it has to be from the same state as the one in which you are buying the medication, and it leaves the seller some latitude in what to accept.

Possibly some states have more restrictive rules. Or particular sellers might be more leery about what they are willing to accept.

[1] https://www.fda.gov/drugs/information-drug-class/legal-requi...

Re:After decades, FDA moves to pull ineffective decongestant... by _moof on Friday November 08, 2024 @02:22AM (#42084937)
The FDA rule doesn't restrict the IDs but the phrase "that is considered acceptable by the seller" lets the pharmacy put any restrictions in place they want. They can tell you it has to be hot pink and glow-in-the-dark and you've got no choice but to deal with it.
Re:After decades, FDA moves to pull ineffective decongestant... by arcticbull on Friday November 08, 2024 @02:37AM (#42085012)
While true as long as they're in compliance with the law, wouldn't they want to sell all the Sudafed they can? They can deny service to anyone for pretty much any reason. No shirt, no shoes, no Sudafed or anything else. So yeah, but in reality it isn't aligned with their interests and if they don't want to serve you they can always find a different justification.
Re:After decades, FDA moves to pull ineffective decongestant... by safety1st on Friday November 08, 2024 @02:53AM (#42085083)
Maybe they want that, maybe they don't. Retail drug stores in the US are an oligopoly, that industry may not be a monopoly (yet) but they don't function under perfect competition. Maybe if you're the management or the shareholders of a retail drug chain you're just kind of shrugging your shoulders and working on the next merger at this point since the fewer competitors you have, the less hard you have to work for the customer's dollar.
Re:After decades, FDA moves to pull ineffective decongestant... by jkaplowitz on Friday November 08, 2024 @04:58AM (#42085668)
The “acceptable by the seller” wording only applies if the ID is not issued by “the State” or “the Federal Government”. Wouldn’t the latter option mean that a US passport, a green card, a Global Entry card, or a NEXUS card must be accepted as suitable ID by any seller in any state? All of those are issued by the feds.
Re:After decades, FDA moves to pull ineffective decongestant... by potato3732842 on Friday November 08, 2024 @06:07AM (#42085928)
And the pharmacy has the state regulators breathing down their neck so being super uptight about it is the obvious choice.

Of course all of this is stupid in a world where the real junkies use fentanyl and there's other easy ways to make meth.

Re:After decades, FDA moves to pull ineffective decongestant... by vrc on Friday November 08, 2024 @07:25AM (#42086323)
States like MA legally only accept MA IDs and federal govt IDs for age verification. That’s why a lot of bars and packies will turn people away or ask for additional proof like CC’s. You’re more likely to be held liable for misconduct if the license you accepted is out of state.
Re:After decades, FDA moves to pull ineffective decongestant... by jkaplowitz on Friday November 08, 2024 @04:59AM (#42085675)
Any seller in any state should have to accept a federally issued ID such as a US passport, no?
Re:After decades, FDA moves to pull ineffective decongestant... by vrc on Friday November 08, 2024 @07:25AM (#42086328)
Yes but then you’d have to carry that for domestic travel.
Re:After decades, FDA moves to pull ineffective decongestant... by jkaplowitz on Friday November 08, 2024 @09:25PM (#42092114)
The wallet-sized passport card is a great solution for that case then. It’s much cheaper than the regular passport book (and you are allowed to have both at once), doesn’t invalidate your regular passport book if it gets lost or stolen, and is also usable to go between the US and Canada by land or sea without having to bring the passport book with you. For people with a Global Entry or NEXUS card, that card also works for every case where the passport card does (and more).

Green card holders also have a convenient wallet size for their green card, and they’re legally required to carry it with them at all times while in the US anyway.

Re:After decades, FDA moves to pull ineffective decongestant... by seattle_spring on Friday November 08, 2024 @01:30AM (#42084679)
That's not universally applicable, as I've purchased it in Washington plenty of times with an Oregon ID.
Re:After decades, FDA moves to pull ineffective decongestant... by bigfatkitten on Friday November 08, 2024 @02:40AM (#42085020)
I've purchased Sudafed in Nevada with a foreign drivers' license with no issues.
Re:After decades, FDA moves to pull ineffective decongestant... by esperent on Friday November 08, 2024 @02:58AM (#42085106)
Here in Vietnam it's completely impossible to get pseudoephedrine at all and I think it's the same in all Asian countries. I even resorted to trying to buy some ephedra tea (Chinese medicinal herb from which ephedrine was first discovered). I ordered a box of tea bags from Shopee.vn and rather amusingly received an envelope with the amount I had paid including shipping in cash and an apology letter saying they could no longer sell this herb and please don't leave a bad review.

However, a few months earlier due to a Google translate mixup where I thought I was ordering peppermint oil, I got 100ml of sassafras oil [0]. It's a precursor to MDMA and at least as restricted as pseudoephedrine.

https://en.m.wikipedia.org/wiki/Safrole

Re:After decades, FDA moves to pull ineffective decongestant... by exe34 on Friday November 08, 2024 @04:50AM (#42085636)
just been banned in the UK. was the only thing that worked on my allergies.

edit: my bad, no it's codeine linctus that was banned, there was talk of making pseudoephedrine prescription only but that hasn't gone through.

Re:After decades, FDA moves to pull ineffective decongestant... by pj1115 on Friday November 08, 2024 @05:37AM (#42085807)
Pseudoephedrine, banned? That's news to me, I bought some OTC a couple of weeks ago.
Re:After decades, FDA moves to pull ineffective decongestant... by angry_octet on Friday November 08, 2024 @06:06AM (#42085923)
It's readily available in Thailand and Indonesia. You can get it mixed with paracetamol OTC in Singapore, but almost everything in Singapore requires a prescription (even e.g. throat lozenges) so find a doctor if you're staying for a while. In Malaysia you need a prescription.
Re:After decades, FDA moves to pull ineffective decongestant... by cowsandmilk on Friday November 08, 2024 @04:14AM (#42085481)
I’ve definitely purchased Sudafed in Seattle with a Virginia Drivers License.
Re:After decades, FDA moves to pull ineffective decongestant... by Pxtl on Friday November 08, 2024 @04:15PM (#42090530)
Once again, big thanks to paranoid "mark of the beast" conspiracy theorists with funny ideas about federal government IDs and digital IDs.

We have the technology. "Behind the counter" could just mean a vending machine with good ID tech instead of queuing up for an overworked pharmacist behind a dozen people.

Re:After decades, FDA moves to pull ineffective decongestant... by echelon on Thursday November 07, 2024 @11:36PM (#42084172)
Pseudoephedrine being pulled from the shelves is one of the biggest crimes of our time.

Pseudoephedrine should be easy and plentiful to obtain. I don't care if people use it to make meth. What they do in their private time doesn't concern me. Not being able to get Sudafed when I'm sick kills me. It's not like those people won't be able to get meth some other way.

We let people buy cars and cause 43,000 automobile deaths a year. People should be able to live life without stuffy noses. Maybe license people to buy meds and take it away if they abuse it? That's better than the draconian system we have now.

And don't get me started on ADHD medication and their shortages.

Edit: and there are 178,000 alcohol related deaths per year in the US. If you're going to allow that without prohibition, then please let us unstuff our noses.

I'm tired of living in a nanny state when we let people buy and own guns and swords and flamethrowers. Simply hiking on a mountain can kill you. Must we install guardrails on all the high places?

It's not that bad of a negative externality. Honestly. Not relative to all the other ones we've deemed acceptable. This is weird picking and choosing that doesn't make sense.

Re:After decades, FDA moves to pull ineffective decongestant... by equestria on Friday November 08, 2024 @12:39AM (#42084474)
> Maybe license people to buy meds and take it away if they abuse it? That's better than the draconian system we have now.

I sympathize with your broader point, but... how is that better? "Sorry, you were buying too much nasal decongestant a decade ago, so no cancer medication for you"?

Re:After decades, FDA moves to pull ineffective decongestant... by otherme123 on Friday November 08, 2024 @01:23AM (#42084647)
I understood your parent comment in a specific drug way: you can buy pseudo until your license to buy that specific compound, or maybe a group or related chemicals, is revoked. But you can still get any other compound.

Not that different from current situation: we have all our "license" to buy scheduled compounds revoked, but we still can get a lot of other compounds.

Re:After decades, FDA moves to pull ineffective decongestant... by renewiltord on Friday November 08, 2024 @02:12AM (#42084878)
How is that any better than the current system which is just “no cancer medication for you”?
Re:After decades, FDA moves to pull ineffective decongestant... by PeeMcGee on Friday November 08, 2024 @12:50AM (#42084517)
I think they were deliberately pointing out the absurdity by comparing it to other far more dangerous things we just waive off if you have a license.
Re:After decades, FDA moves to pull ineffective decongestant... by Nursie on Friday November 08, 2024 @12:39AM (#42084475)
I read a study here in Australia a little while ago that showed that removal of easily accessible pseudoephedrine had done nothing to either stop the proliferation of clandestine labs, nor curtail the availability of crystal meth. They just switched to different syntheses, and there are still large-scale imports that sometimes get caught, sometimes don't.

People were still trying to claim the program was a success because they had stopped gangs getting pseudo as a precursor.

But so what? it's done literally nothing to stop criminals profiting, nor to stop people getting addicted to meth, with all the associated public health and petty-criminal consequences of that. And now it's harder for ordinary people to get effective decongestant.

It just seems that nobody is willing to admit the whole thing was pointless.

Re:After decades, FDA moves to pull ineffective decongestant... by EdwardDiego on Friday November 08, 2024 @01:33AM (#42084691)
Same in New Zealand, we removed pseudoephedrine as an option unless you had a special dispensation from the Ministry of Health - mainly due to pharmacies being ram-raided for the pseudo.

The end result? The gangs just started importing pseudo, before later just switching to importing methamphetamine directly (something that Australia's deportation policies really helped with as the "501s" as we call them that were deported back to NZ often had existing connections that could facilitate the direct importation of meth).

It's a really interesting supply chain that involves organised crime groups in multiple countries, often starts in India for the precursors, then clandestine labs in Laos/Vietnam/Thailand overseen by Chinese groups in conjunction with local groups, then smuggled via the Pacific Islands, notably Fiji and Samoa where the Chinese groups have established transshipment facilities, before being smuggled into Australia and NZ by local groups who then distribute and supply it.

A new development has been the Central American cartels branching out from cocaine to meth so there's been a bunch of meth coming directly from the Americas.

Re:After decades, FDA moves to pull ineffective decongestant... by epistasis on Friday November 08, 2024 @12:51AM (#42084523)
The car stat is a good example of trying new policies to lower car deaths! They are the greatest risk to my children's lives and I find it terrifying that we let them roll around everywhere so close to people, like we do in parking lots.

>Maybe license people to buy meds and take it away if they abuse it?

I'm a bit confused, because you can buy it already with an ID, correct? You don't even need a purchasing license, just a drivers license or other government ID.

Re:After decades, FDA moves to pull ineffective decongestant... by 0x457 on Friday November 08, 2024 @05:42PM (#42091050)
No, they mean you get a license to buy meds and that license gets revoked if you abuse them. Not that you need a _driving_ license to buy meds.
Re:After decades, FDA moves to pull ineffective decongestant... by loopdoend on Friday November 08, 2024 @01:01AM (#42084567)
It is even easier to get in Singapore.
Re:After decades, FDA moves to pull ineffective decongestant... by radicality on Friday November 08, 2024 @03:25AM (#42085244)
Really? As in, in spite of how bonkers the overall import rules in Singapore are?

I just travelled there few weeks ago, and the government websites made it sound like it’s best to just not bring any pills at all (or chewing gum).

- Tool you can to use to check active ingredients and whether its allowed: https://www.hsa.gov.sg/personal-medication/check-requirement...

- Anything that might be controlled/require prescription, have to apply for permit it to bring it: https://www.hsa.gov.sg/personal-medication/submit-applicatio...

- They provide a tool to show illegal health products. Better not bring one of them: https://oscar.hsa.gov.sg/Publication/ahpdm/faces/AHPPublicat...

Re:After decades, FDA moves to pull ineffective decongestant... by refurb on Friday November 08, 2024 @03:31AM (#42085276)
It's the same in Singapore.

You can only buy from a pharmacist (behind the counter) and you need to provide your national ID number. Your purchase is put in a database that any pharmacist can see.

Re:After decades, FDA moves to pull ineffective decongestant... by cyberax on Friday November 08, 2024 @01:20AM (#42084637)
> Pseudoephedrine being pulled from the shelves is one of the biggest crimes of our time.

What's even worse, modern pseudoephedrine is produced in a form that makes meth synthesis from it extremely tedious and generally impossible in home conditions: https://pmc.ncbi.nlm.nih.gov/articles/PMC3793278/

Re:After decades, FDA moves to pull ineffective decongestant... by 15155 on Friday November 08, 2024 @06:27AM (#42086001)
99% of pseudoephedrine sold is not this form and this specific product has already been debunked years ago with Mississippi's complete ban (and their refusal to allow it.)

I remember the video of the pharma rep or cop or whoever trying to make meth out of the new pills and the product getting squishy. Months later, a different video was published, where some household solvent was used to easily pull the very-dissolvable pseudoephedrine salts from the paste.

Re:After decades, FDA moves to pull ineffective decongestant... by JumpCrisscross on Friday November 08, 2024 @01:27AM (#42084660)
> Pseudoephedrine should be easy and plentiful to obtain

Anything that isn't directly physically addictive (e.g. opiates) or subject to a tragedy of the commons (e.g. antibiotics) should be over the counter.

Re:After decades, FDA moves to pull ineffective decongestant... by AnthonyMouse on Friday November 08, 2024 @02:54AM (#42085090)
Addictive is the argument in favor of making it over the counter. Addicts will do whatever it takes to get their fix, so if there isn't a legal path, they buy on the street, creating a funding source for organized crime and spurring gang violence.

Then, because the black market is already in violation of the law, there are no purity standards. The customer who thinks they're getting Adderall or codeine is actually getting fentanyl because fentanyl's much higher potency makes it easier to smuggle, but for the same reason makes it much more prone to addiction and overdose, especially when careless street dealers get their proportions wrong. All of which is avoided if you just let them buy it from the pharmacy.

Notice that there is no thriving black market for antibiotics propping up international drug cartels, because they're not addictive.

Re:After decades, FDA moves to pull ineffective decongestant... by TeMPOraL on Friday November 08, 2024 @03:37AM (#42085309)
Strongly agreed, with one correction: black markets are driven by shortage. The role of addiction is in creating demand, and at the same time making authorities restrict access.

There is no thriving black market for antibiotics, because they are accessible when you need them (and most people need them very infrequently for a short duration). In contrast, I believe there is a black market for insulin in the US, and that's because of how ridiculously expensive it is. Exuberant pricing is a form of restricting access, too.

Re:After decades, FDA moves to pull ineffective decongestant... by BenjiWiebe on Saturday November 09, 2024 @02:01PM (#42096188)
*Exorbitant?
Re:After decades, FDA moves to pull ineffective decongestant... by JumpCrisscross on Friday November 08, 2024 @03:25AM (#42085250)
> Addictive is the argument in favor of making it over the counter

You want to control the general population’s access to physically-addictive substances to control addiction. Managing addicts is not a pharmaceutical matter.

Re:After decades, FDA moves to pull ineffective decongestant... by echelon on Friday November 08, 2024 @10:20AM (#42087511)
We don't control access to alcohol, paints/volatiles, aerosols, and so many other things people abuse.

Just yesterday on Reddit there was a thread that went viral for "cutter" reviews on Shein razor blades, with cutesy language like "beautiful beans for my followers" (referring to subcutaneous dermal appearance when deeply cut open). Every product can be abused in horrible ways. It's the nature of the stochastic bubble we're in. People will find every nook and cranny of the human experience.

You can't stop this stuff from happening. So at least let the normal use cases that benefit society through. Don't put everyone else in the same straight jacket. We don't deserve to be punished for the bad gradients some people fall into.

Re:After decades, FDA moves to pull ineffective decongestant... by marcosdumay on Friday November 08, 2024 @03:02PM (#42090023)
Ok, if you want to control it, than mediate access through a public health institution.
Re:After decades, FDA moves to pull ineffective decongestant... by cnity on Friday November 08, 2024 @06:26AM (#42085998)
You can get it in the UK, fortunately.[0]

0: https://www.nhs.uk/medicines/pseudoephedrine/about-pseudoeph...

Re:After decades, FDA moves to pull ineffective decongestant... by qzw on Friday November 08, 2024 @08:34AM (#42086719)
It is a bit silly to ban a useful drug like pseudoephedrine while large parts of the US is in an opioid crisis. Kind of like how lawn darts have disappeared from stores but you can still buy all sorts of weapons. That said, a lot of laws are based on established traditions. Alcohol use goes back thousands of years, and the other things you mentioned such as vehicles and weapons are tools going back even longer. They are dangerous tools, to be sure, and often employed unnecessarily in this society, but tools nonetheless. Once upon a time most people depended on their weapons and vehicles to survive, and differences in the quality and quantity of weapons and transportation technology have historically led to the rise and fall of entire civilizations.
Re:After decades, FDA moves to pull ineffective decongestant... by heartbreak on Friday November 08, 2024 @03:05PM (#42090042)
> I don't care if people use it to make meth. What they do in their private time doesn't concern me.

You ever seen a meth lab that blew up?

Re:After decades, FDA moves to pull ineffective decongestant... by echelon on Friday November 08, 2024 @07:29PM (#42091595)
I've seen fireworks, gas stoves, portable electric heaters, peanut oil deep fried turkeys, etc.
Re:After decades, FDA moves to pull ineffective decongestant... by cyberax on Friday November 08, 2024 @01:25AM (#42084651)
How did I miss this article before?!? Love it!

> Other side effects may include violent urges or, similarly, the urge to be successful in business or finance. ... > We expect that the simultaneous trends of restricting pseudoephedrine sales while N-methylamphetamine becomes less expensive and of higher purity will make the methods presented here increasingly attractive.

Re:After decades, FDA moves to pull ineffective decongestant... by LM358 on Friday November 08, 2024 @03:07AM (#42085156)
"simple and convenient" does a lot of heavy lifting in this paper - n-BuLi, chromium hexacarbonyl and MoOPH (had to look that one up!) is not something you find outside of a well equipped lab and shouldn't be touched by anyone who isn't highly experienced.
Re:After decades, FDA moves to pull ineffective decongestant... by winocm on Friday November 08, 2024 @05:32AM (#42085788)
Fun fact, there (was?) is a isomer of methamphetamine that is actually over the counter, levomethamphetamine was often found in Vicks brand inhalers, though they appear to be discontinued, being replaced with a ‘non-medicated’ version. There are apparently generic inhalers that still do contain it though.

https://www.science.org/content/blog-post/other-methamphetam...

Re:After decades, FDA moves to pull ineffective decongestant... by stzsch on Friday November 08, 2024 @05:48AM (#42085855)
See also selegiline, which partially metabolizes to levoamphetamine and levomethamphetamine. Not OTC though (antidepressant).
Re:After decades, FDA moves to pull ineffective decongestant... by winocm on Friday November 08, 2024 @06:09AM (#42085941)
Oh man, I have fun stories about selegiline.
Re:After decades, FDA moves to pull ineffective decongestant... by hyperdimension on Friday November 08, 2024 @09:18AM (#42087020)
Come on, you can't be vague like that and expect no one to ask. Do tell!
Re:After decades, FDA moves to pull ineffective decongestant... by winocm on Friday November 08, 2024 @03:09PM (#42090064)
If you really would like to know and enjoy mortal suffering, just contact me privately.
Re:After decades, FDA moves to pull ineffective decongestant... by hinkley on Friday November 08, 2024 @12:38PM (#42088743)
The problem I found was that nobody wanted to deal with the database after a certain time in the evening. Odds are good you don’t admit you’re coming down with something until after work. Or at least admit to yourself that medicine would be helpful. So by the time you see you’re out of Sudafed or can’t find the old pack, it’s often too late to go to the store to get a new one before morning.
Re:After decades, FDA moves to pull ineffective decongestant... by ykonstant on Friday November 08, 2024 @01:18PM (#42089149)
That's actually hilarious.