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Re:Suspected head of $21B crime syndicate may be world’s mos... by version_five on Tuesday November 02, 2021 @06:55PM (#29088620)
I think drugs should be legal (or decriminalized) but probably with at least two categories, which no doubt causes it's own set of problems:

1. Recreational, like marijuana and alcohol and many hallucinogens, where regulating and taxing is the best solution, to deter organized crime and make sure people are getting the product they want to get

2. Harmful (and the definition is tough here) like meth and heroin, where the goal is something closer to medically supervised use, and breaking the habit where appropriate, but also making sure people are getting real drugs and not resorting to more dangerous alternatives or those of unknown origin.

The point isn't that drugs are good, it's that people will do them anyway, so how do you remove the criminal element and keep people safer under the circumstances. I agree that they shouldn't sell meth at convenience stores, but someone addicted should be able to talk to a doctor and get it, and not have to buy some dangerous unknown thing off the street.

I imagine if this happened, the next fight would be social control advocate groups pushing for currently legal drugs (alcohol) to me moved to my category 2. People's own puritan values and a hatred of the idea that someone else may be enjoying themselves in a way they don't endorse are a (the) main root cause of all the societal problems with drugs imo

Re:Suspected head of $21B crime syndicate may be world’s mos... by dillondoyle on Tuesday November 02, 2021 @07:40PM (#29089066)
It's very easy to make an argument alcohol is more dangerous than heroin. especially in a regulated market with clean well dosed drugs.

Alcohol already kills more people than heroin. Sure you could argue maybe perhaps more people will do heroin if it's legal, but I highly doubt that.

I 100% agree on the puritan social preaching being a hinderance to support. People don't want to "support someones addiction" which means basically no resources.

I'm for full legalization personally.

Re:Suspected head of $21B crime syndicate may be world’s mos... by arcticbull on Tuesday November 02, 2021 @07:55PM (#29089218)
Here's an Economist article which breaks down drug harm, and ranks drugs accordingly. The chart shows that in totality, alcohol does more harm than heroin. [1]

[1] https://www.economist.com/graphic-detail/2019/06/25/what-is-...

Re:Suspected head of $21B crime syndicate may be world’s mos... by version_five on Tuesday November 02, 2021 @08:02PM (#29089292)
Any study like this takes a very narrow view of good vs bad. Can we even begin to quantify how much good alcohol has done? The amount of fun and sociability it contributes to is staggering. Same with marijuana and no doubt other drugs (i have basically no knowledge of the upside of hard drugs so can't speak to it, but if you google Benzidrine there is an Atlantic article that mentions amphetamine and some upside).

I don't disagree that there are vary bad sides to drug use, same as for driving, soda pop, cheese, whatever. But we shouldn't pretend in a vacuum that there are not also positives, and short of severe societal consequences (like with some hard drugs, perhaps) people should generally be able to choose for themselves

Re:Suspected head of $21B crime syndicate may be world’s mos... by belval on Tuesday November 02, 2021 @08:22PM (#29089473)
Those studies also often disregard the fact that alcohol consumption is not always (even often) for intoxication, people drink wine and cocktails for the enjoyment of the drink itself, not so much for the effect it has on their behaviour.
Re:Suspected head of $21B crime syndicate may be world’s mos... by Nursie on Tuesday November 02, 2021 @10:58PM (#29090640)
It's both, even in those situations. By the time someone is doing that, it's likely they've been through years of habituation to alcohol and their brain is wired to respond positively to the stuff because of the effect.

To non-drinkers who have never drunk alcohol or have not for a long time, it seems these flavours don't work so well, and all wine is quite nasty (this is anecdotal data from observing such folk).

So yes, subjectively I love the taste of a good red, or a well made cocktail, or a fine rum. But the effect of the drug is bound up in my neurological response to it as well as just the flavour.

Re:Suspected head of $21B crime syndicate may be world’s mos... by version_five on Tuesday November 02, 2021 @08:48PM (#29089711)
Yes, for alcohol in particular (maybe theres also a parallel with cigars) there is the whole other dimension that it's an important part of food, gastronomy or whatever you'd call it. If I get wine pairings with my meal, it has almost nothing to do with intoxication, it's about opening up the senses and adding to what I'm eating. That puts alcohol, as it is normally used, in a very special category compared to ther drugs.
Re:Suspected head of $21B crime syndicate may be world’s mos... by arcticbull on Tuesday November 02, 2021 @09:02PM (#29089834)
I bet an LSD pairing would open up the senses and add to what you're eating too! ;)

Granted, the world may fall in on itself and there's a small risk time will stop.

Re:Suspected head of $21B crime syndicate may be world’s mos... by renewiltord on Tuesday November 02, 2021 @09:35PM (#29090086)
Personally, I enjoy sushi on shrooms quite a bit. Especially that feeling of wasabi. Mmmm. Just elevates the experience. Wine is good. The taste sensation changes quite a bit but the texture awareness on psilocybin is unmatched for me.

It’s a gastronomic loss that people don’t experience this.

Re:Suspected head of $21B crime syndicate may be world’s mos... by version_five on Tuesday November 02, 2021 @10:50PM (#29090583)
I did mushrooms a bit in the 90s and remember either feeling sick of having no appetite (and then being really hungry afterward). Thinking back I really don't remember any instance of eating while on them. Just for the sake of comparison, its interesting. I can picture how one could become caught up in some sensation to do with eating.
Re:Suspected head of $21B crime syndicate may be world’s mos... by tata71 on Wednesday November 03, 2021 @09:41AM (#29094409)
I smelled pork being cooked near me much differently than I otherwise would have.
Re:Suspected head of $21B crime syndicate may be world’s mos... by 4ggr0 on Wednesday November 03, 2021 @04:19AM (#29092201)
I think shrooms/psilocybin are a loss in general, and I'm really sad that they're so unfairly heavily regulated.
Re:Suspected head of $21B crime syndicate may be world’s mos... by arcticbull on Tuesday November 02, 2021 @10:12PM (#29090323)
Note token.
Re:Suspected head of $21B crime syndicate may be world’s mos... by SNosTrAnDbLe on Wednesday November 03, 2021 @12:59AM (#29091247)
The state of Gujarat in India prohibits the consumption of alcohol. A lot of its cities are considered to the safest for woman in India. While alcohol is available illegally, its consumption is still frowned upon. This relative safety is sometimes correlated with Gujarat being a dry state. I tried to search for any studies but could not find any so it may just be a coincidence. I have lived in Gujarat and the night life is very family friendly and usually involves lots of street food instead of bars and restaurants!
Re:Suspected head of $21B crime syndicate may be world’s mos... by potamic on Wednesday November 03, 2021 @04:38AM (#29092299)
By what metric is Gujarat considered safe? It ranks as one of the worst states in India for human trafficking.

https://en.wikipedia.org/wiki/Indian_states_ranking_by_incid...

Re:Suspected head of $21B crime syndicate may be world’s mos... by metb on Wednesday November 03, 2021 @05:50AM (#29092633)
Are we using Wikipedia as a reliable source of hard metric data these days?
Re:Suspected head of $21B crime syndicate may be world’s mos... by mschuster91 on Wednesday November 03, 2021 @05:55AM (#29092666)
The article directly states in its first paragraph that the list originates from a government source:

> This is a list of states and union territories of India ranked by incidents of human trafficking as of 2016, and is based on the number of convicted cases. The list is compiled from the '2016 Crime in India Report' published by National Crime Records Bureau (NCRB), Government of India.[1]

Of course this kind of data has its own issues (e.g. incidents that don't end in a conviction because of bribery or police/judicial misconduct or that don't get caught by police at all don't end up in it), but it's probably the qualitatively best data you can get.

Re:Suspected head of $21B crime syndicate may be world’s mos... by vagrantJin on Wednesday November 03, 2021 @03:52AM (#29092077)
> A lot of its cities are considered to the safest for woman in India

I like how you phrased this as if it were a meaningful metric. Is "safe for women" more useful than safe for everybody including children?

Do you have perhaps things relating to brawls, muggings, drunk driving arrests and accidents, drunk pedestrian road fatalities, suicide rates as determinants for a safe city? I'd think they're more reasonable than a vague metric as "safest for women"

Re:Suspected head of $21B crime syndicate may be world’s mos... by dillondoyle on Tuesday November 02, 2021 @11:44PM (#29090903)
I have the same argument for all drugs. Including opiates. Which do in fact do a lot of good. For a while. Until they don't. Similar to alcohol. The problem is it's way harder to be a casual opiate user than it is an alcoholic.
Re:Suspected head of $21B crime syndicate may be world’s mos... by zd123 on Tuesday November 02, 2021 @08:29PM (#29089544)
Heres the peer reviewed article upon which the article is based.

https://www.ias.org.uk/uploads/pdf/News%20stories/dnutt-lanc...

I would encourage you to read it before marking it as a “narrow view”. It is literally taking a broad view factoring in societal impacts. It is written by highly respected experts.

Alcohol absolutely has severe societal impacts: violence rates are positively correlated to rate of alcohol consumption; clogging up hospitals with self inflicted injuries, driving under the influence, health issues (liver damage), clogging up emergency departments on the weekend etc.

I mean I could literally go on. Of all the drugs alcohol really shouldn’t be as easily available as it is.

Personally I find the argument that it does “good” pretty wishy washy and more driven by societal bias toward it as an accepted medium for socialistion. Alternatives do exist.

Re:Suspected head of $21B crime syndicate may be world’s mos... by pstuart on Tuesday November 02, 2021 @08:52PM (#29089739)
Most of the harm from heroin stems from it being illegal and unregulated. It obviously would be abused if legal and readily available but even that would be better addressed by spending money on health/prevention vs. police/courts/jails.

My brother died of a heroin overdose many years ago. If it had been legal, pure, and known quality that likely wouldn't have happened (he could still have been affected by addiction like our mother with alcohol, but he wouldn't be dead).

Re:Suspected head of $21B crime syndicate may be world’s mos... by rectang on Tuesday November 02, 2021 @09:11PM (#29089907)
I wish that things could have been different for your brother, your mother, and you and all those affected.
Re:Suspected head of $21B crime syndicate may be world’s mos... by pstuart on Tuesday November 02, 2021 @10:00PM (#29090254)
Thank you so much. I do too, as well as for all the others who suffer because of these misguided policies.

It so easily could be changed, but we are collectively trapped by the delusion that the only route to safety is to make drugs illegal. You'll see it here on HN, in this thread, about how the "dangerous" drugs should not be readily available because people will get hurt if society lets them have legal access.

It's such an easily solvable problem and we collectively support the worst possible way to deal with it -- it's crazy making.

Re:Suspected head of $21B crime syndicate may be world’s mos... by Ginden on Wednesday November 03, 2021 @06:40AM (#29092933)
> If it had been legal, pure, and known quality that likely wouldn't have happened (he could still have been affected by addiction like our mother with alcohol, but he wouldn't be dead).

Overdoses on opiates happen even with legal opiates [1] and it's related to tolerance mechanisms. You become tolerant to euphoric effects much faster than you become tolerant to respiratory depression and nausea.

This basically makes opiates much more dangerous than any other drug class.

[1] https://www.cdc.gov/drugoverdose/featured-topics/overdose-de... - prescription opioids alone contribute to 9.2% of overdose deaths excluding alcohol.

Re:Suspected head of $21B crime syndicate may be world’s mos... by allturtles on Wednesday November 03, 2021 @01:42AM (#29091449)
The study is based on a group of drug experts going in a room and assigning point values to harm of different drugs. It's not really a 'study' at all in the empirical sense, it's just a social group expressing its pre-existing biases.
Re:Suspected head of $21B crime syndicate may be world’s mos... by 14 on Tuesday November 02, 2021 @08:42PM (#29089661)
You sound like these guys from high school I once knew justifying their cocaine use. Saying things like “it makes me way more social” “I am not shy when I do cocaine”. Don’t forget almost all off the feel good drugs once you stop you have to come down and when that dopamine runs out your day feels like shit and all that fun you had is buried with regret and depression. Yes people can have fun but if we added all the fun trips vs bad trips would we as a society see it as a net gain? I have been on a train with a drug user lost out of their mind swearing and threatening people. So if you are counting all the fun drugs have brought you need to count those also.
Re:Suspected head of $21B crime syndicate may be world’s mos... by SapporoChris on Tuesday November 02, 2021 @08:26PM (#29089516)
Based on the chart, it looks like I would benefit by giving up alcohol and switching to heroin. However, I am a little dubious and not quite ready to make the switch. I shopped around, and none of the stores even had heroin.
Re:Suspected head of $21B crime syndicate may be world’s mos... by exsmelliarmus on Tuesday November 02, 2021 @09:13PM (#29089920)
Yeah nope. The barrier to entry difference here is staggering. A beer versus a needle in the arm?!?
Re:Suspected head of $21B crime syndicate may be world’s mos... by __float on Tuesday November 02, 2021 @09:24PM (#29090015)
https://en.wikipedia.org/wiki/Heroin#Routes_of_administratio...

Wikipedia is surprisingly thorough on most drug articles. But you may even have seen such pipes for sale in stores... it can be smoked. Smoking various substances is pretty well accepted by society, even.

Re:Suspected head of $21B crime syndicate may be world’s mos... by sterlind on Tuesday November 02, 2021 @11:40PM (#29090884)
People smoked in opium dens, after all. Maybe bars succeeded and opium dens failed because alcohol's just been in Western culture longer.
Re:Suspected head of $21B crime syndicate may be world’s mos... by boomboomsubban on Wednesday November 03, 2021 @12:36AM (#29091147)
I am only aware of the US history, but the early laws barring opium dens had nothing to do with health concerns, they were anti-Chinese laws. At the same time as the dens were starting to be shut down, opium was a hugely popular panacea available in over the counter in every drug store.
Re:Suspected head of $21B crime syndicate may be world’s mos... by dillondoyle on Tuesday November 02, 2021 @11:43PM (#29090898)
you don't need to shoot it. eat, smoke, boof. eating would have less bang for your buck but for a first time it's WAY cheaper than a night out at the club ;)
Re:Suspected head of $21B crime syndicate may be world’s mos... by short12 on Tuesday November 02, 2021 @09:22PM (#29089993)
Both can be ordered easily online and delivered to your house.

And needles are not even required

Re:Suspected head of $21B crime syndicate may be world’s mos... by tata71 on Tuesday November 02, 2021 @09:41PM (#29090131)
Because everyone stops at one beer, or just one hit of drugs!
Re:Suspected head of $21B crime syndicate may be world’s mos... by arcticbull on Tuesday November 02, 2021 @09:01PM (#29089821)
Based on the chart it would be better for those around you if you switched to heroin. It would be a bit worse for you. According to the chart it would be better for everyone if you picked up a Bolivian marching powder habit haha.
Re:Suspected head of $21B crime syndicate may be world’s mos... by yadaeno on Wednesday November 03, 2021 @03:25AM (#29091953)
What about harm per user?

I personally know 3 people that have tried heroin. It quickly has destroyed two of their lives. 0 ability to hold a job, maintain relationships, if not for family they would be homeless. My other friend was able to use it in moderation for a decade but recently going down the same path.

The idea that heroin is less harmful then alcohol is absolutely ludicrous. The reason it has done less economic harm is because it's less accessable, extremely taboo, illegal, etc.

Re:Suspected head of $21B crime syndicate may be world’s mos... by adriand on Wednesday November 03, 2021 @07:16AM (#29093132)
Heroin is a painkiller like the other opiates, and it works on mental pain too, not just on physical pain. Most well-adjusted people without a history of trauma do not want to try heroin or if they do, do not tend to become addicted to it.

If we don’t let people have access to pure drugs under conditions that limit the risk of harm, then we should also provide them with the mental health supports they need. People will go to great lengths to kill their pain, including risking death and imprisonment. They shouldn’t be forced into choices like that.

Re:Suspected head of $21B crime syndicate may be world’s mos... by jeltz on Wednesday November 03, 2021 @08:29AM (#29093687)
Yeah, I had to take opiates due to an injury and I hated the feeling (foggy mind and hard to focus). It would be really unlikely for me to become addicted to them. Yes, there is still the physical addiction but I so there is some risk but I wanted to quit taking my opiates as soon as I could when I was on them.
Re:Suspected head of $21B crime syndicate may be world’s mos... by playpause on Wednesday November 03, 2021 @04:27AM (#29092242)
The harms you describe could also be put down to it being illegal.

I am not saying that’s the only difference. I agree heroin is obviously far more powerful a drug, and far more addictive. So I don’t think it should be fully legalised and sold in shops. But making it legal for addicts to use under medical supervision in special licensed places seems a sensible compromise. It would probably scale down the black market (which reduces drug pushing on new users), it would reduce immediate dangers (heroin is pretty safe when administered properly in a clean environment), and it would probably help addicts get off it and build a new life (it would remove a lot of the chaos from their lives and would expose them to drug counsellors).

Re:Suspected head of $21B crime syndicate may be world’s mos... by tchalla on Wednesday November 03, 2021 @04:43AM (#29092317)
> Alcohol’s position at the top is partly the result of its widespread use, which causes greater harms to others (crack cocaine is considered the most harmful drug for the user).
Re:Suspected head of $21B crime syndicate may be world’s mos... by arein3 on Wednesday November 03, 2021 @05:08AM (#29092436)
leave it to such geniuses to figure out that alcohol does more harm than heroin, put them in charge of society and you get the clown world we have now

this is so dumb, I have no words

Re:Suspected head of $21B crime syndicate may be world’s mos... by jollybean on Tuesday November 02, 2021 @08:03PM (#29089305)
It's worth contemplating the ills of alcohol - but it is available in any quantity to anyone who wants it, and it's socially acceptable.

If we sold Opiates/Fentanyl to anyone who wanted it it, in whatever quantities, and there were no social stigma, with 80% of teens doing it 'at least a little bit' before age 21, and 97% of the adult population consuming opiates at least on some occasion again with 'easy access' ... the harm would be orders of magnitude greater than alcohol.

Re:Suspected head of $21B crime syndicate may be world’s mos... by arcticbull on Tuesday November 02, 2021 @08:29PM (#29089541)
Potentially, but that's not really what Portugal found when they decriminalized all drugs in 2001 (not legalized, mind you). They saw usage remain roughly constant, but all the negative effects associated with drug use dropped precipitously. [1]

[1] https://www.theguardian.com/news/2017/dec/05/portugals-radic...

Re:Suspected head of $21B crime syndicate may be world’s mos... by jollybean on Tuesday November 02, 2021 @08:46PM (#29089699)
Decriminalization is a fairly marginal step away from the status quo and is nothing like true legalization with the inherent distribution, social acceptance etc..
Re:Suspected head of $21B crime syndicate may be world’s mos... by arcticbull on Tuesday November 02, 2021 @09:17PM (#29089949)
I guess the question I would have is - and this isn't meant to come across as though I have a preconceived answer - what evidence do we have that legalization (plus, for instance, a ban on marketing) would actually increase usage? I know it's intuitive to think it would, but is there data? We do know for a fact that usage of many hard drugs is increasing when illegal. And this is on top of all the negative outcomes associated with making it illegal - guns, gangs, prison, felony convictions. Is making it illegal slowing the uptake? By how much? Is it making the problem worse?
Re:Suspected head of $21B crime syndicate may be world’s mos... by Broken_Hippo on Tuesday November 02, 2021 @09:17PM (#29089953)
What makes you think that legalisation would mean social acceptance?

It doesn't.

Re:Suspected head of $21B crime syndicate may be world’s mos... by nobody9999 on Tuesday November 02, 2021 @10:50PM (#29090586)
> What makes you think that legalisation would mean social acceptance?

>It doesn't.

Absolutely correct. cf. Tobacco smoking.

Re:Suspected head of $21B crime syndicate may be world’s mos... by jollybean on Wednesday November 03, 2021 @01:27PM (#29097726)
"Absolutely correct. cf. Tobacco smoking. "

???

Tobacco indicates to us that the answer is 'absolutely false', not 'absolutely correct'

Smoking is absolutely a socially accepted behaviour.

We ban it in certain areas largely because it's intrusive to others.

It's not fully condoned obviously we don't put it in film or advertise it - but it is a widely consumed product.

If Opiates ever reached the penetration of smoking, we'd have a situation as bad as COVID.

We already have a public health crisis with Opiods, and they are very aggressively suppressed and controlled.

True legalization (i.e. more than decriminalization) would wield some pretty scary problems.

I don't even understand how this is not just a rhetorical argument.

Re:Suspected head of $21B crime syndicate may be world’s mos... by OJFord on Wednesday November 03, 2021 @07:52AM (#29093402)
I'm not so sure about that, it's illegal indoors (publicly) in the UK since 2005 iirc, my impression is that it's less 'socially acceptable', to the extent that can be quantified, now than it was when smokers and non-smokers shared a pub.
Re:Suspected head of $21B crime syndicate may be world’s mos... by nobody9999 on Wednesday November 03, 2021 @08:20AM (#29093605)
>I'm not so sure about that, it's illegal indoors (publicly) in the UK since 2005 iirc, my impression is that it's less 'socially acceptable', to the extent that can be quantified, now than it was when smokers and non-smokers shared a pub.

A reasonable point.

However, smoking indoors is illegal because smoking is less 'socially acceptable', not the other way around.

There has been, over the last 30 years or so, a concerted effort (with warnings on US cigarette packs, more dire ones on UK packs, and disgusting photos on packs elsewhere in Europe), as well as marketing/advertising pushes to make smoking less acceptable.

And (in the US, at least, not sure about elsewhere), many fewer people smoke and those who do are often harassed/berated even when they smoke where it's legal to do so.

As such, I'd expect similar results (given similar efforts) for other drugs.

Before/after photos of meth heads/heroin addicts on packaging, marketing/advertising efforts, etc. would likely have a similar effect.

What's more (again, at least in the US, although I'd expect it'd be true wherever such drugs are criminalized), the costs associated with such efforts, as well as treatment programs for those who need them, would be significantly less costly than the monies spent on interdiction, enforcement and incarceration.

Perhaps I'm missing something important here?

Re:Suspected head of $21B crime syndicate may be world’s mos... by jollybean on Wednesday November 03, 2021 @01:37PM (#29097873)
"smoking indoors is illegal because smoking is less 'socially acceptable'"

No - this is false.

It's illegal because it's harmful to others - and - it's generally a nuisance i.e. it really smells quite a lot.

Chewing tobacco is completely legal 'indoors' and it has many of the same negative effects. It's not even up for consideration in terms of banning. You can chew it on the Subway, at the Office.

"Perhaps I'm missing something important here?"

Yes, you're missing the fact that we already do heavy suppression of Meth/Heroin i.e. teaching kids how terrible it is, featuring it in films as extremely negative, positioning it as 'totally socially taboo and unacceptable behaviour'.

Selling it in stores legally is both an increase in availability, and a significant reduction in social taboo.

This is not even an argument.

Widespread availability and lessening of social taboos of an extremely addictive substance, which addicts develop a tolerance for and quickly move onto more powerful substances (Fentanyl) would yield a major public health crisis. We already have on on our hands.

70 000 dead from OD in the USA in 2019 - and rising 32 000 car accident deaths in the USA 2019 - and going down

It's growing quite a lot in the Midwest.

[1] https://www.cdc.gov/drugoverdose/deaths/2013-2017-increase.h...

Re:Suspected head of $21B crime syndicate may be world’s mos... by nobody9999 on Wednesday November 03, 2021 @02:26PM (#29098506)
>"smoking indoors is illegal because smoking is less 'socially acceptable'"

>No - this is false.

>It's illegal because it's harmful to others - and - it's generally a nuisance i.e. it really smells quite a lot.

And it was less harmful or a nuisance before it became illegal? And it smelled less too? Please.

Smoking indoors was banned because of the effort to make it less socially acceptable.

If it were otherwise, those bans would have been in place 40 years ago. We knew it was harmful in the 1960s (actually, even before that, but various societies didn't start trying to make it less socially acceptable until the 1970s).

It wasn't until the 1990s/2000s when such bans went into effect. Why? Because smoking had become less socially acceptable -- through conscious efforts[0][1] over decades to make it so.

>Chewing tobacco is completely legal 'indoors' and it has many of the same negative effects. It's not even up for consideration in terms of banning. You can chew it on the Subway, at the Office.

So what? I was (and explicitly said so) talking about smoking, not chew.

You are apparently ignorant of history. Which makes it hard to have a conversation that, for obvious reasons, needs to take that history into account. So let's not.

[0] https://truthinitiative.org/research-resources/tobacco-indus...

[1] https://en.wikipedia.org/wiki/Regulation_of_nicotine_marketi...

Re:Suspected head of $21B crime syndicate may be world’s mos... by nobody9999 on Wednesday November 03, 2021 @02:28PM (#29098536)
>Yes, you're missing the fact that we already do heavy suppression of Meth/Heroin i.e. teaching kids how terrible it is, featuring it in films as extremely negative, positioning it as 'totally socially taboo and unacceptable behaviour'.

>Selling it in stores legally is both an increase in availability, and a significant reduction in social taboo.

Who, exactly are you responding to here? Because it isn't me.

I never even implied that such drugs should be fully legalized/commercialized.

Go and build, then knock down your straw man somewhere else. I'm not interested.

Re:Suspected head of $21B crime syndicate may be world’s mos... by OJFord on Wednesday November 03, 2021 @02:49PM (#29098779)
> However, smoking indoors is illegal because smoking is less 'socially acceptable', not the other way around.

It polled at 54% in favour of the ban in 2004 (and I was slightly off on the date, enacted 2006 taking effect 2007):

https://www.centreforpublicimpact.org/case-study/smoking-ban...

It's only anecdotal, but my point is that I think it's considerably less socially acceptable (indoors or out) now than it was when it came in. And I think as a result. I think a lot of people smoked less and less and many gave up altogether, and the fewer people do something the less acceptable it seems.

Re:Suspected head of $21B crime syndicate may be world’s mos... by jollybean on Tuesday November 02, 2021 @09:39PM (#29090120)
Sure it does.

Something that is illegal, is by definition a social taboo. The removal of that taboo implies more acceptance. The fact that more people use it will only increase acceptance by word of mouth etc. and that's at minimum.

The only question is by how much will usage increase?

Already, with severe legal restrictions and controls, opioid use is rapidly increasing the US, which is what we call 'extreme product market fit' (i.e. the drugs 'fits' our dopamine pathways) see [1]

The other major factors are 1) addiction / tolerance and 2) self-medication 3) money, i.e. capitalism.

As for 1)

"Roughly 21 to 29 percent of patients prescribed Opioids for chronic pain misuse them"

"An estimated 4 to 6 percent who misuse prescription Opioids transition to heroin." [2]

Those are just simple, top line numbers, and very potent at that.

Even with limited marketing and 'soft non-acceptance / promotion' - I believe it's something that vast numbers of people will seek it out 'just to party' or for 'the Vegas' trip etc. and especially for 2) i.e. as an easy painkiller/mood moderator which will leave a lot of people addicted.

As for 3)

If it's legal and profits can be made, they will be made. Investors at large may be 'moral' but there is always plenty of 'highly amoral' capital to do whatever, and in this case, it'd be producing the product with the most 'product market fit' in existence.

Increased use of opiods etc. will have no upside, only downside. It has to be regulated and controlled, it's best to keep it at a minimum.

In Canada they prescribe them by the pill, not the 1/2 bottle, i.e. you get a single pill for toot surgery because its just so addictive.

[1] https://en.wikipedia.org/wiki/Opioid_epidemic_in_the_United_...

[2] https://www.drugabuse.gov/drug-topics/opioids/opioid-overdos...

Re:Suspected head of $21B crime syndicate may be world’s mos... by arcticbull on Tuesday November 02, 2021 @10:13PM (#29090334)
> Something that is illegal, is by definition a social taboo. The removal of that taboo implies more acceptance.

They're correlated, but it's not a causative relationship. It's not illegal for a dominatrix to step on your genitals and make you call her mommy. That's taboo, and legal. On the other hand, jaywalking is illegal - and not a taboo.

> The only question is by how much will usage increase?

That is the question, but I think we should be open to the answer being zero or even negative - just as we are open to the answer being positive. How much drug addiction and usage is furthered by throwing addicts into prison where the only escape is more drugs?

How about the folks who make it out of prison but cannot get jobs because of their felony possession charges, who then lose their friends and family, and once again escape into drugs?

This is a multifaceted challenge.

Re:Suspected head of $21B crime syndicate may be world’s mos... by jollybean on Wednesday November 03, 2021 @01:59PM (#29098193)
"I think we should be open to the answer being zero or even negative - just as we are open to the answer being positive"

Not really, and this is the problem with this thread and issue in general.

Sure, we should be open to the possibility of certain things, but that doesn't mean they are reasonable or even likely, and it distracts from more obvious and likely scenarios.

When debating issues, people have a tendency to be rhetorical and not pragmatic.

Opiods are not like meth or coke: there is a big, legal market for them (!) so we have lots of exposure to what happens when we prescribe 1/2 a bottle for patients, vs only the 1 or 2 pills for post-surgery.

In those 'mini cases' of increased access i.e. where you have a leftover bottle of Oxycodone, problems are much more likely than otherwise.

It's ridiculous to suggest that someone having a bottle of Oxycodone available (i.e. greater access) is somehow going to be 'less likely' to develop problems than someone who does.

We already have a lot of behavioural science, and the laws of supply and demand to help us out, but even that is pedantic in the face of anyone with exposure to this issue.

To imply that legalization and widespread availability of a highly addictive substance would 'reduce' usage would be to deny everything we understand.

If you lower the cost of something, consumption increases.

There isn't even a decent rhetorical argument for why 'consumption would decrease' in the face of easy access. I suppose that some behaviours that are 'social taboos' make them more attractive, but that's not a strong argument.

Ask a regular doctor or pharmacist who has to prescribe Opioids what they think would happen if we just made them 'over the counter' like Tylenol.

The only group of people who would condone expansion of access, are some healthcare professionals who support harm reduction policies, and even then, that would be very limited access.

We are where we are for the next few decades at least until either powerful new technologies change the game, we develop much more powerful social abilities, or for some reason the substances are just eradicated from common awareness.

Re:Suspected head of $21B crime syndicate may be world’s mos... by Broken_Hippo on Wednesday November 03, 2021 @05:37AM (#29092583)
In the US, it is pretty taboo to have occult practices, yet it is legal. Having an open marital relationship is pretty taboo to a lot of folks, yet - legal.

Pot isn't all that taboo, yet it is very illegal in some states and illegal at the federal level.

And fwiw: I don't have the article now, but perhaps part of the reason you don't get a bottle for tooth surgery is because a combination of ibuprofen and paracet (tylenol) is generally enough especially if you have time off work to rest.

Norway gives a pre-counted package of 20 that are in blister packs, even though it is addictive.

Even with limited marketing and 'soft non-acceptance / promotion' - I believe it's something that vast numbers of people will seek it out 'just to party' or for 'the Vegas' trip etc. and especially for 2) i.e. as an easy painkiller/mood moderator which will leave a lot of people addicted.

If you say so. I mean, you are acting like we are just going to give folks as many drugs as they want, in an uncontrolled fashion - and it doesn't have to be like that at all. You don't need investors to be 'moral' - because obviously, they probably aren't going to be considering how businesses treat folks now - you just need laws and enforcement to look out for people.

By the way: Upsides are things like being able to have a professional give you a single, proper dose for partying and give folks information - actual, truthful information that isn't a DARE-esque scare tactic ("Its just so addictive..."). A professional does screening. ID required. If we log prescriptions and sudafed, we can do this. We can give information. Folks that are addicted can get maintenance doses and get actual help.

Edit: FWIW: The crisis in the US is more than just drug availability. Being able to get help if you find yourself addicted would help lots. At the same time, things like paid time off to rest after surgeries would help as well.

Heroin doesn't make folks immediately addicted, neither do pills. And with things being illegal, we realistically have no clue how many people take them as a party drug occasionally without ever getting addicted.

Re:Suspected head of $21B crime syndicate may be world’s mos... by hellbannedguy on Tuesday November 02, 2021 @10:14PM (#29090339)
There are some old studies on opioid (prescription type meds) use in rest homes.

They found that most patients did not want to increase their dose of the opioid. They just didn't want to be cut off the meds they were given. It makes so much sence.

I'm to lazy to look it up.

I don't understand this all, or nothing mentality when it comes to drugs.

I truly feel the American Opioid crisis could have been less devastating if government provided patients/addicts with with access to the medication with limits.

Actually, bupenorpine would probally be the better drug to make available to anyone that wanted it.

Re:Suspected head of $21B crime syndicate may be world’s mos... by version_five on Tuesday November 02, 2021 @08:13PM (#29089392)
Fentanyl, and especially dangerous fentanyl basically only exists because of prohibition.

Ignoring that most people wouldn't try hard drugs even if they were more readily available, the current opiate problem is more like if alcohol was unregulated and made in bathtubs everywhere, and every few beers had methanol in it instead of ethanol.

Re:Suspected head of $21B crime syndicate may be world’s mos... by com2kid on Tuesday November 02, 2021 @08:25PM (#29089509)
> Ignoring that most people wouldn't try hard drugs even if they were more readily available, the current opiate problem is more like if alcohol was unregulated and made in bathtubs everywhere, and every few beers had methanol in it instead of ethanol.

While I am generally all for harm reduction and even legalization, 19th century history shows what happens when opium becomes readily available to a country with no limitations.

Re:Suspected head of $21B crime syndicate may be world’s mos... by Ginden on Wednesday November 03, 2021 @06:47AM (#29092975)
Arguably, people in XIX century wasn't really aware of opioid addiction. Significant portion of treated troops in US were hooked up on opioids, because physicians weren't aware of issues.
Re:Suspected head of $21B crime syndicate may be world’s mos... by Nursie on Tuesday November 02, 2021 @11:03PM (#29090673)
> the harm would be orders of magnitude greater than alcohol.

This is something of an assertion. We can certainly anticipate some effects, by looking at countries that have had opium problems in the past. But that would have to be countered by looking at the deaths, physical and mental health consequences, violence and all sorts of other problems caused by alcohol, and doing so honestly.

There is a huge tendency to write it off as "just a beer" and think "I can handle it" and then compare your relationship with alcohol to the worst addicts of another drug, neatly ignoring the many millions who end up on a dark path through booze.

Re:Suspected head of $21B crime syndicate may be world’s mos... by pstuart on Tuesday November 02, 2021 @08:57PM (#29089785)
I disagree. There would be "social caution" (yes it feels good but you'll get trapped). We could finally have grown up conversations about self-medicating and how to be a mindful consumer.
Re:Suspected head of $21B crime syndicate may be world’s mos... by tayo42 on Wednesday November 03, 2021 @01:17AM (#29091329)
If heroine was legal right now would you start using it?
Re:Suspected head of $21B crime syndicate may be world’s mos... by virgilp on Wednesday November 03, 2021 @02:35AM (#29091675)
Also, nuclear bombs killed less people than guns did - so it's very easy to make an argument that guns are in fact more dangerous than nuclear weapons. Since US allows gun ownership, it should also allow private citizens to produce and own nuclear weapons.
Re:Suspected head of $21B crime syndicate may be world’s mos... by chadash on Tuesday November 02, 2021 @10:59PM (#29090644)
> alcohol already kills more people than heroin.

Yeah and it kills more people than nuclear bombs and pet tigers combined. But unlike nuclear gonna, pet tigers and heroin, alcohol is used by perhaps a majority of adults, so the numbers need to be adjusted accordingly.

Re:Suspected head of $21B crime syndicate may be world’s mos... by hanniabu on Tuesday November 02, 2021 @08:36PM (#29089603)
A big part of the reason for alcohol deaths is how it's social acceptable and heavily advertised and encouraged. If it was treated the same way as cigarettes where it can't be advertised in commercials and movies with drinking are rated R then we'd be in a much better state. However the situation is much worse for alcohol in terms of social acceptance and how engrained it is so I imagine there will be way more pushback than when these changes were made for cigarettes.
Re:Suspected head of $21B crime syndicate may be world’s mos... by tayo42 on Wednesday November 03, 2021 @01:19AM (#29091339)
There was also serious anti smoking propaganda for awhile. Smoking was practically killed off until vaping came around.
Re:Suspected head of $21B crime syndicate may be world’s mos... by galaxyLogic on Tuesday November 02, 2021 @09:32PM (#29090069)
That makes obvious sense. Why isn't alcohol advertising illegal?
Re:Suspected head of $21B crime syndicate may be world’s mos... by hanniabu on Friday November 05, 2021 @07:56PM (#29125995)
It is, at least digital advertising. I'm not sure if they can do posters and billboards and the like.
Re:Suspected head of $21B crime syndicate may be world’s mos... by rectang on Tuesday November 02, 2021 @08:12PM (#29089386)
Are you in favor of unfettered capitalist exploitation of addicts?

Because "full legalization" means bringing the full firepower of commercial enterprise to bear in order to create addicts, and then profit from the "personal choices" the addicts were statistically guaranteed to make.

If I advocate for decriminalization and limited sale exclusively through state-run shops forbidden from marketing their products... does that make me a "puritan"?

Re:Suspected head of $21B crime syndicate may be world’s mos... by dillondoyle on Wednesday November 03, 2021 @03:15PM (#29099053)
I lean more towards government run free drugs. though people will always want more mdma and coke etc than a government would likely consider a 'safe' dose so maybe some type of hybrid. And yes ban all drug advertisements period including alcohol and tobacco.

Though simply having government inspected pure drugs in set pre-sized doses + no ads would be huge for ODs and communicable diseases ('kit' included).

Speaking of religion dominating this debate, lots of southern states and utah have state run or heavily regulated alcohol laws. Maybe similar to that model in that there is still a 'free market' but the middle man is the gov.

On the last. No.

I'm talking about how the base of a lot of addiction services is founded by or based in religion.

How lots of homeless shelters - in some cities the only spaces - are run by religious orgs with mandates to receive services.

When I talk with people who are not in the recovery community I often hear things like, 'i'm not going to give money to that homeless person because they'll just spend it on drugs.'

Or why should they get free housing. They're just going to get high in it. They don't deserve what I consider basic human necessities.

That whole construct - which sounds like maybe you and I have some similar views - drives an us against them frame, instead of looking wider at the commercial 'who' interests.

When housing is a profit driver and artificially limited, it's better for the capital that we fight amongst ourselves instead of pushing that we should all have affordable (in many cases that means free) access to housing.

I also hear similar puritan - in the sense these opinion holders think they are saving, purifying, rebirthing, baptizing to reform whatever.

Like jails & criminalizing behavior & poverty as a vehicle for what they consider fixing peoples lives.

'they are their own maker,' 'god is guiding everything is a lesson tough love,' as addicts are forcefully detoxed in solitary or dangerous jails without medical supervision (which is torture for this convo on opiates. and can be very dangerous for other kinds of gaba drugs).

Elected sheriffs are the worst... Often preaching their own religious beliefs to win elections because that's what their county constituents believe. Arpaio as an example of inhumane and illegal treatment.

Re:Suspected head of $21B crime syndicate may be world’s mos... by Broken_Hippo on Tuesday November 02, 2021 @09:19PM (#29089973)
Alcohol is legal, sometimes is sold in state-run shops, and has controls to keep some of the capitalist stuff in check. You know, not advertising to children and stuff.

Besides, we already have the capitalist exploitation of addicts in the form of rehab.

Re:Suspected head of $21B crime syndicate may be world’s mos... by tata71 on Tuesday November 02, 2021 @09:23PM (#29090003)
*and the prison industrial complex"
Re:Suspected head of $21B crime syndicate may be world’s mos... by KennyBlanken on Tuesday November 02, 2021 @11:37PM (#29090866)
Alcohol also is a major contributing factor in most violent and domestic crime, it's the single greatest cause of deadly road collisions, etc.
Re:Suspected head of $21B crime syndicate may be world’s mos... by Broken_Hippo on Wednesday November 03, 2021 @05:26AM (#29092527)
Ok. So?

Having alcohol illegal - or even just simply decriminalized - doesn't stop that. In fact, we were worse off since it allowed violent crime to rise instead of doing stuff like solving domestic abuse (this was one of the arguments for prohibition). Folks died since strength and purity wasn't regulated.

Which realistically hits at the point of the exchange - effects of legalisation.

Re:Suspected head of $21B crime syndicate may be world’s mos... by grayfaced on Tuesday November 02, 2021 @11:19PM (#29090757)
Alcohol addiction is horrible but there are also a lot of people that drink socially that never have a problem.

I'm curious, is there an equivalent with heroin? Can you sustain at casual usage for years without succumbing to addiction?

Re:Suspected head of $21B crime syndicate may be world’s mos... by dillondoyle on Tuesday November 02, 2021 @11:45PM (#29090908)
Some but not many. Pills are more likely. But yeah opiates for sure are far harder to be a casual user of than alcohol.
Re:Suspected head of $21B crime syndicate may be world’s mos... by sneak on Tuesday November 02, 2021 @09:28PM (#29090042)
Tobacco kills 7x more than opiates in the USA every day, week, month, and year.
Re:Suspected head of $21B crime syndicate may be world’s mos... by cgh on Tuesday November 02, 2021 @07:01PM (#29088682)
Yeah, I agree on all points (I’m a proponent of legalization and live in a country with legal pot). I’ve witnessed first-hand the effects of prolonged meth addiction and it is not pretty. Your point of making it available by prescription is the good and obvious path. But will still be available as a party drug via illegal means of production and distribution.
Re:Suspected head of $21B crime syndicate may be world’s mos... by Bellend on Tuesday November 02, 2021 @07:36PM (#29089020)
It's such a difficult topic. In the very very end, the person has to decide to make an effort to come off the drug. Their pathways are either become a mess (I got nothing to live for) or OD. If that is the option, is some kind of local drug room the only solution? Get everything free here consumed on the premises and we will keep an eye on you over the X days/months/years and try to help you, sectioned upstairs for 3 months if needed?
Re:Suspected head of $21B crime syndicate may be world’s mos... by pas on Tuesday November 02, 2021 @07:20PM (#29088868)
Make it legal as a party drog in a form that makes it very hard to overdose. (Also there should be delayed and extended release version, which lowers the chance of addiction forming.)

Also there's no reason to not regulate some stuff like sportcars. Go to a speedway go fast there, not where kids play on the street.

Re:Suspected head of $21B crime syndicate may be world’s mos... by dylan604 on Tuesday November 02, 2021 @07:28PM (#29088942)
Addicts with the "normal" meth vs "delayed" meth would still seek out the "normal" version.
Re:Suspected head of $21B crime syndicate may be world’s mos... by pas on Wednesday November 03, 2021 @04:17AM (#29092193)
Current addicts need treatment anyway. If they can't find meth they will use bath salts or whatever their dealer can get them.

The important question is about harm reduction. People trying drugs without support. The current system already produces addicts.

Can a different system lead to better results, plus as a side-quest defunds the cartels?

Re:Suspected head of $21B crime syndicate may be world’s mos... by dylan604 on Wednesday November 03, 2021 @11:00AM (#29095621)
What addicts need and what addicts want are totally different concepts. You're looking at this like legalizing drugs will make addicts all suddenly see the light and seek treatment. That's just living in lalaland. Sure, some might, but that's not going to be a large percentage. I'm looking at this like I've been around too many addicts and know that legalization social programs will not solve addiction at all.
Re:Suspected head of $21B crime syndicate may be world’s mos... by eptcyka on Tuesday November 02, 2021 @07:31PM (#29088967)
But meth already is being sold to the public. At pharmacies and with a prescription, not to the general public in convenience stores.

I don't think that people hate seeing others having fun, but rather its the demonization of drugs in the post war era to quell social movements that has now entrenched a deep hatered to substances not blessed back then that is the bigger issue.

Re:Suspected head of $21B crime syndicate may be world’s mos... by asxd on Tuesday November 02, 2021 @07:52PM (#29089196)
Maybe you mean Adderall? I've read methamphetamine is sometimes prescribed, but my understanding is it's extremely rare.

There is a real problem with some drugs that become physically addictive. A person can fairly easily drink alcohol or take adderall regularly without suffering physical withdrawals. I'm not so sure this would be the case with heroin, for instance. I don't think in those instances the drugs were demonized to quell social movements, but because they were substances that too easily consumed people's lives.

Re:Suspected head of $21B crime syndicate may be world’s mos... by Lazare on Tuesday November 02, 2021 @08:27PM (#29089521)
Methamphetamine is much less frequently prescribed than other forms of amphetamines for ADHD, but I wouldn't say "extremely rare". And there's very little evidence it's any more addictive or harmful than normal amphetamines.

I also think you're conflating addiction to dependency or withdrawal symptoms. Physical withdrawal symptoms are extremely common with stimulants - then again, they're common for basically all other drugs too. Adderall, caffeine, hell, even Tylenol all have withdrawal symptoms. If you're a daily coffee drinker, going a day without will likely cause a splitting migraine and some personality changes for a day or two! Many OTC nasal sprays for hayfever are known for having ferocious withdrawal symptoms, but they aren't addictive or abusable.

People who abuse stimulants take a dose vastly higher than any therapeutic dose. The effects end up being very different. You mention heroin, but heroin itself was originally marketed - for years! - as a non-addictive alternative to morphine, and was sold as a cough suppressant. Many people used it; most didn't get addicted. Cocaine was a fairly common additive to drinks for years; Thomas Edison was famously a fan of https://en.wikipedia.org/wiki/Vin_Mariani (as were two popes and numerous other famous figures).

There's nothing magical about heroin. Prescribe a therapeutic dose of a strong opioid, and maybe 1% (the data here is bad, but most studies cluster around this point) of your patients will get addicted and start abusing it (by taking a vastly higher dose); the other 99% will not. We keep demonising drugs, seemingly almost at random, but it doesn't seem to have much to do with the nature of the drugs.

Re:Suspected head of $21B crime syndicate may be world’s mos... by asxd on Wednesday November 03, 2021 @03:36AM (#29092004)
Thanks for this thoughtful reply. I should probably not have commented on frequency of meth prescriptions, my only reference point is that it's never been brought up to me by my doctor and don't know any friends who take it for ADHD.

Regarding withdrawal symptoms, it's again anecdotal on my end. I have been taking prescribed adderall for ADD since I was a teen. When I do go off it for a prolonged period of time, I don't notice withdrawal so much as a mood shift and a decline in productivity. I'm more or less comfortable being lethargic and lazy when I'm off it, but I take it because I think it makes me better at being a person (ability to focus for one, but also just taking the time to do menial but important every-day tasks I might otherwise let go by the wayside, for example).

I think this speaks to your point though, that in correct dosages the withdrawal in (pharmaceutical grade) drugs can be safely mitigated.

On a slight tangent, I'd like to point to the ongoing opioid crisis. I wonder if the reason it occurred was not only because doctors made the drug readily available, but because so many people were told by their doctor--a generally trusted authority--to take larger doses? If it were only accessibility that led to the crisis, there may be some truth to the idea that some drugs are true public health hazards.

Apologies for rambling a bit, I'm somewhat on the fence about this topic, and I know this is a complicated issue to unravel.

Re:Suspected head of $21B crime syndicate may be world’s mos... by Lazare on Wednesday November 10, 2021 @07:46PM (#29183056)
The opioid crisis is a difficult topic, but the role of legal opioids in it is highly contested.

Note that the rate of opioid prescription in the US had dropped by nearly 50% since 2012 [1], while the overdose rate has more than doubled [2]][3]. Meanwhile the same crackdown that has led to a huge decline in prescriptions has also led to a decrease in the amount prescribed, to the extent that there is strong evidence it is harming patients because doctors are so afraid of losing their license they are unwilling to prescribe the correct therapeutic dose to patients.

A study in JAMA recently found that when doctors reduce the dosage of pain medication prescribed to long term opioid therapy, it leads to a threefold increase in suicide attempts and a 69% increase in overdoses[4]. In other words, the federal guidelines adopted to try and ensure that the drug was less readily available from doctors and prescribed in smaller doses seems likely to have cost a significant number of lives.

There don't seem to be easy answers, and the driving forces behind (and possible solutions to) the massive increase in overdose deaths in the US remain elusive. But at a minimum a simple model of "it's caused by doctors giving people prescriptions for painkillers" seems to not be supported by evidence at this time.

[1]: https://www.cdc.gov/drugoverdose/rxrate-maps/index.html

[2]: https://www.drugabuse.gov/drug-topics/trends-statistics/over...

[3]: https://apnews.com/article/overdose-deaths-record-covid-pand...

[4]: https://jamanetwork.com/journals/jama/fullarticle/2782643?gu...

Re:Suspected head of $21B crime syndicate may be world’s mos... by DanBC on Thursday November 11, 2021 @05:43AM (#29186555)
> The opioid crisis is a difficult topic, but the role of legal opioids in it is highly contested.

No, it really isn't. US doctors were massively over-prescribing very strong opioids and telling patients that these were not addictive.

This meant that communities were flooded with clean, pure, strong, opioids. This supply was legal. The fact that it subsequently got diverted into the misuse supply chain doesn't alter the known facts of the opioid crisis - that there was massive over-supply of legal meds.

Re:Suspected head of $21B crime syndicate may be world’s mos... by qwerty456127 on Tuesday November 02, 2021 @09:20PM (#29089982)
> And there's very little evidence it's any more addictive or harmful than normal amphetamines.

Well, I won't say "just try and compare" because recommending to try that would be a devil's advice but the difference is huge and I don't need any scientific paper to confirm that. For a person having actual ADHD amphetamine can be a reasonable tool to manage it sustainably, at the same time meth would at least cause rapid tolerance build-up leading them to increase dosage very fast and face all sorts of health issues. You also won't be able to return to amphetamine soon after having tried meth, the former is going to have almost no effect until your brain chemistry actually recovers.

Re:Suspected head of $21B crime syndicate may be world’s mos... by sobani on Thursday November 04, 2021 @12:37PM (#29109301)
https://astralcodexten.substack.com/p/know-your-amphetamines

Start reading from "There's a lot of confusion around the difference between amphetamine and methamphetamine."

Most relevant quote: "Moreover, there are no known neurobiological differences in action between METH and AMPH that would account for the [supposedly] greater addictive, rewarding, or psychomotor properties of METH."

Re:Suspected head of $21B crime syndicate may be world’s mos... by gavinray on Tuesday November 02, 2021 @08:04PM (#29089312)
No, they mean "Desoxyn", literal D-Methamphetamine.

GoodRx hilariously has great meth coupons:

https://m.goodrx.com/desoxyn

Re:Suspected head of $21B crime syndicate may be world’s mos... by asxd on Tuesday November 02, 2021 @08:07PM (#29089347)
Oh my, that's hilarious, in a twisted sort of way. I was aware that meth was prescribed, but I guess I had no reference point for how prevalent it might be.
Re:Suspected head of $21B crime syndicate may be world’s mos... by loxias on Tuesday November 02, 2021 @10:38PM (#29090502)
I'm on a very similar one, which also has a GoodRx coupon.

In case you're not familiar with the details of psychopharmacology, or are lucky enough to have a more "normal" brain, it's quite common for one to spend a long time with their doctor, doing trial and error with different compounds that are variants on the same structure, even different isomers can have a noticeable effect for the patient.

At one stop on my journey, I was prescribed dexedrine, which I previously had only heard of in the context of the great Paul Erdos.

Sadly, despite my hopes and dreams, there was no noticeable increase in the proliferation of my math output.

Re:Suspected head of $21B crime syndicate may be world’s mos... by asxd on Wednesday November 03, 2021 @03:47AM (#29092056)
I was in a similar boat, and spent a decent chunk of time during adolescence going through that trial-and-error process. At one point we tried Ritalin, which ended up just giving me horrible headaches and causing my grades to plummet. Dexedrine, on the other hand, was much more effective for me, even more so than adderall for some reason. I know Ritalin works for a lot of folks, and I find it pretty fascinating that the same medication can affect different people in such drastically different ways.

Completely tangential, but regarding Paul Erdos, I recall hearing about a story where a colleague of his was concerned about his amphetamine use and offered to pay him a sum of money to go cold turkey for a month. Erdos was pretty adamant that amphetamines were a boon to his math research, so he went cold turkey for a month to prove he could, took the money, and then promptly resumed his usage.

Not sure if it's true or what lessons are to be learned there, but it's a fun story :)

Re:Suspected head of $21B crime syndicate may be world’s mos... by loxias on Wednesday November 03, 2021 @04:33AM (#29092272)
> I know Ritalin works for a lot of folks, and I find it pretty fascinating that the same medication can affect different people in such drastically different ways.

Same!! (Ritalin doesn't work on me either).

On my "journey to what works" the least pleasant, and most amusing in retrospect, was Strattera. Somehow, that medicine cranked up the "impatient asshole" knob in my brain to 11. I was cursing out people on the street for no rational reason, and carrying myself with more confidence than I've ever felt in my life. Things where I would normally have a patience of minutes became seconds. I found myself getting pissed off at dear friends for talking too slowly, interrupting them "can you fucking speed up please?". I quit after 5 days. :)

At the time, my doctor seemed skeptical of the side effect, but a decade later I found documented evidence of it in others. Curiously, the medicine works quite effectively, no side effects, for someone who shares half my DNA. Brains are weird!

Tangentially, I've heard a variant of that Erdos story too! Clearly it must be true. ;-)

Re:Suspected head of $21B crime syndicate may be world’s mos... by Nursie on Wednesday November 03, 2021 @05:33AM (#29092567)
> even different isomers can have a noticeable effect for the patient

Case in point - L-methamphetamine is or was used in Vicks inhalers in some countries, notably the US, as it has none of the euphoriant effects of D-methamphetamine but it does still cause vasoconstriction, which can help with a blocked nose!

Re:Suspected head of $21B crime syndicate may be world’s mos... by bshipp on Tuesday November 02, 2021 @08:20PM (#29089460)
I knew I was taking an amphetamine derivative but I had no idea my ADHD prescription was literally the same as meth. of course, I'm taking a tiny daily amount. No wonder they give me such a hassle about filling my script when I'm traveling!
Re:Suspected head of $21B crime syndicate may be world’s mos... by hn_throwaway_99 on Tuesday November 02, 2021 @08:04PM (#29089309)
Prescription meth goes by the trade name Desoxyn, and it's not the same thing as Adderall.
Re:Suspected head of $21B crime syndicate may be world’s mos... by quantum_solanum on Tuesday November 02, 2021 @09:51PM (#29090192)
> A person can fairly easily drink alcohol or take adderall regularly without suffering physical withdrawals

though alcohol is notably one of the few common drugs (along with benzos) where withdrawal can actually kill you.

Re:Suspected head of $21B crime syndicate may be world’s mos... by pugets on Tuesday November 02, 2021 @08:39PM (#29089633)
What percent of methamphetamine addicts would actually have qualified for a Desoxyn prescription before they started using? This health site [0] says 16,000 prescriptions for Desoxyn are written in the US each year, contrasted to the 12 million Americans who abuse meth.

[0] https://montarebehavioralhealth.com/why-is-desoxyn-on-the-do...

Re:Suspected head of $21B crime syndicate may be world’s mos... by xyzzyz on Tuesday November 02, 2021 @07:48PM (#29089144)
Prescription meth use is much different than recreational use. Dosages are way larger, and so is method of administration. This makes enormous difference.

Consider dextrometorphan. This is a common over the counter cough medication. It can also be used recreationally - but the recreational dose is 30 times the therapeutic dose. Amphetamine is similar: methheads are not swallowing a single pill of Adderall, like medical users are.

Re:Suspected head of $21B crime syndicate may be world’s mos... by rectang on Tuesday November 02, 2021 @07:30PM (#29088963)
The main question is not about the freedom of users, but about the freedom of the sort of entrepreneurs who read Hacker News to market legal drugs to heavy users as aggressively as possible.

Addicts are where the money is. If you want to make bank on drugs, it's all about speeding up the downward spiral of addiction and extracting maximum value from addicts while they're spiraling.

Re:Suspected head of $21B crime syndicate may be world’s mos... by mam4 on Wednesday November 03, 2021 @04:43AM (#29092316)
Despite the insane propaganda these days i'm not sure weed is "not harmful" when i look at my friends who turned to it in times of sadness. It's wayy worse than alchool in terms of damage.

And i do all kind of hard drugs

Re:Suspected head of $21B crime syndicate may be world’s mos... by servytor on Tuesday November 02, 2021 @10:21PM (#29090382)
This documentary on Seattle's homeless problem[0] says that homelessness and drug addiction are the same thing. It claims that almost every homeless person is addicted, and that society as a whole is ignoring the connection for some reason.

[0]: https://www.youtube.com/watch?v=bpAi70WWBlw

Re:Suspected head of $21B crime syndicate may be world’s mos... by version_five on Tuesday November 02, 2021 @10:38PM (#29090500)
I watched the first few minutes, I think I understand the angle. Do you think there is a causal relationship? I have no doubt that homeless people use drugs in a bad way, and I think homeless problems as described are disgusting and wouldn't want to live somewhere like that. But I think the homelessness and drug use are symptoms of the same problem, untreated mental illness, western society generally... people who think that more criminalization of drugs will make this better are living in a dream world. Do they have these problems in Norway and Portugal? I don't believe it's anywhere near like this, and I don't thinks it's because they are tougher on drugs (I'm open to bein told differently though). Drugs are not some evil waiting to corrupt weak people, they are recreation for most people, and a dangerous escape for a few. Pretending they are a cause instead of a symptom doesnt help anyone
Re:Suspected head of $21B crime syndicate may be world’s mos... by ocdtrekkie on Tuesday November 02, 2021 @07:42PM (#29089094)
The problem with this is simple: A lot of people have agreed marijuana and hallucinogens are harmful, and only alcohol classed in recreation. Prohibition was obviously when alcohol was also considered harmful, and arguably it only crossed the bar back into recreational because enforcement failed so spectacularly.

Which is to say, your idea only makes sense as long as everyone agrees with your classification, which has generally not been the case.

Re:Suspected head of $21B crime syndicate may be world’s mos... by tjs8rj on Wednesday November 03, 2021 @12:42AM (#29091171)
While I agree with most of what you said, the idea that people are only against drugs because of backwardness or selfishness seems off. Is there any society that didn’t ban most drugs?

My preference to ban drugs mainly comes from the harm and way they hack the brain to lower the barrier of that harm. And because they are so powerful, not only do I think it’s immoral to have that harm done to another person, I also think it makes society worse when significant chunks of the population are incapacitated (and hampered from a better life) due to an addictive substance.

Another example of this is gambling, or social media to a lesser degree. We all agree they have harmful effects to the individual, and have strong capacity to make society worse for everyone - even if you don’t participate. So we’re better off in the long term if we contain their addictive powers.

As far as I can tell that’s a pretty progressive and empathetic opinion.

Re:Suspected head of $21B crime syndicate may be world’s mos... by forrestthewoods on Tuesday November 02, 2021 @08:13PM (#29089399)
I don’t understand how anyone can walk around downtown Seattle or San Francisco and say “yes I think legalized OTC heroin and meth is a great idea”.
Re:Suspected head of $21B crime syndicate may be world’s mos... by version_five on Tuesday November 02, 2021 @08:52PM (#29089740)
Because the situation in these cities is largely from the criminalization of drugs?
Re:Suspected head of $21B crime syndicate may be world’s mos... by vkou on Tuesday November 02, 2021 @09:02PM (#29089829)
Living in one, and visting the other, I would say that both cities would be better off if addicts could get it at a dispensary, instead of the dealer on 2nd and Pine.

But it's true, there are some people who think that having an addict cause $5000 worth of damage to steal a $500 item that they'll pawn for $50 is preferable to just giving him a goddamn prescription. [1] At least with the status quo, nobody's conscience is troubled...

If your goal is to stop people from being high, criminalization isn't doing it. If your goal is to stop people from taking more and more drugs until they eventually overdose, it's not doing that either. If your goal is to stop functional addicts from going down the drain into non-functional addiction, you're not even hitting the same ball park.

[1] With an optional bonus level of spending $50,000 to prosecute and incarcerate and dump right back onto the street, if your town is into that sort of thing.

Re:Suspected head of $21B crime syndicate may be world’s mos... by will4274 on Tuesday November 02, 2021 @10:59PM (#29090646)
> just giving him a goddamn prescription.

You think we should just give them free drugs in addition to the housing and food we already give them? Because the drugs are cheaper than the robberies?

Look, the simple fact is many people are not entrepreneurial. They work instead of doing drugs because they know they have to in order to have a decent go at life. If you just make being high all day and acceptable and low cost life decision, you could easily see 90% of people in some communities choose that option.

We do actually exist on earth in the pitiful condition that if we all just sit on our asses and do nothing, we'll die.

Re:Suspected head of $21B crime syndicate may be world’s mos... by Nursie on Tuesday November 02, 2021 @11:07PM (#29090686)
> You think we should just give them free drugs in addition to the housing and food we already give them? Because the drugs are cheaper than the robberies?

Does that not seem pragmatic to you?

While we give them those drugs we can make sure they're not getting anything nasty or weird in there so they don't just up and die, and we can help them recover when the opportunity presents.

But if you'd rather live with more petty crime, and more expensive policing, more or less for the sake of being spiteful... well you get where we are today.

> If you just make being high all day and acceptable and low cost life decision, you could easily see 90% of people in some communities choose that option.

I think that would be a damning verdict on how unfulfilling and hopeless those communities have become regardless of drugs.

Re:Suspected head of $21B crime syndicate may be world’s mos... by will4274 on Wednesday November 03, 2021 @02:09AM (#29091558)
It's pragmatic in a thoroughly robotic sense. Most humans have this thing called empathy tho.

> Unfulfilling and hopeless

It's the human condition.

Re:Suspected head of $21B crime syndicate may be world’s mos... by Nursie on Wednesday November 03, 2021 @02:42AM (#29091709)
> Most humans have this thing called empathy tho.

Yeah, and that would surely cause most humans to empathise with other humans suffering from addiction, and help those others the best way they can, by a) reducing harm to the addicts and b) helping them overcome their addiction. The fact that this c) also reduces incident crime levels and reduces suffering for yet another group of humans is surely a bonus.

'Pragmatic' in this case is referring to taking actions you consider morally questionable, but with the aim of reduction of harm all around.

I don't see how this is robotic or lacking in empathy. Quite the opposite.

> It's the human condition.

It's really not, not for 90% of a given community unless there is something else seriously wrong with that community.

Re:Suspected head of $21B crime syndicate may be world’s mos... by nemothekid on Tuesday November 02, 2021 @11:43PM (#29090897)
>in addition to the housing and food we already give them?

In what US state do the homeless get housing? Or do you mean prison?

>Look, the simple fact is many people are not entrepreneurial. They work instead of doing drugs because they know they have to in order to have a decent go at life.

Is this from a study you've read or are you just making shit up? Isn't "Rat Park" psychology 101? This is an incredibly jarring point of view when you also consider many of the heroin addicts where onramped by doctors getting kickbacks from Purdue Pharma.

Re:Suspected head of $21B crime syndicate may be world’s mos... by will4274 on Wednesday November 03, 2021 @02:07AM (#29091553)
What does big Pharma have to do with it? These drugs are incredibly addictive. So addictive that normal people throw their whole lives away from one course of painkillers. Your solution is to let people get them more freely. That means more people throw their lives away
Re:Suspected head of $21B crime syndicate may be world’s mos... by nemothekid on Wednesday November 03, 2021 @09:50AM (#29094513)
>What does big Pharma have to do with it?

You should really research Purdue Pharma litigation if you don't know. Making sweeping general statements without even being aware of one of the biggest pharmaceutical settlements in recent history is surprising. In short, Purdue Pharma was bribing doctors to get patients hooked on Oxycontin.

>Your solution is to let people get them more freely.

My solution has more to do with housing than free drugs. Legalized, controlled, distribution would allow hospitals to more accurately keep track of who is dependent on these drugs, and having stable housing is shown to be a requirement for rehab.

Ultimately, when you look at the homeless problem you have 4 choices: you can kill them, imprison them, house them, or leave them alone. Choices (1) and (2) should never be considered in a free society; leaving choice (3) and (4). Choice (3) would mean some kind of socialized housing (a là Vienna), which is obviously a no-go in America so you find that (4) is the best option that you see implemented in America.

Re:Suspected head of $21B crime syndicate may be world’s mos... by vkou on Wednesday November 03, 2021 @02:57AM (#29091812)
> If you just make being high all day and acceptable and low cost life decision

It's possible that you may think that being a homeless addict with a drug prescription is an 'acceptable low cost life decision'.

I personally don't see how adding 'with a drug prescription' suddenly makes it particularly attractive and low cost. From all I can observe, living in that sort of situation is still utter misery and shit. Can't say I feel one bit of envy for it, when I drive past the onramp tents - even if the drugs were free.

Do you?

Re:Suspected head of $21B crime syndicate may be world’s mos... by TylerE on Tuesday November 02, 2021 @08:34PM (#29089588)
Do you think it being illegal is stoping people form using those drugs?
Re:Suspected head of $21B crime syndicate may be world’s mos... by forrestthewoods on Tuesday November 02, 2021 @09:01PM (#29089822)
Obviously not.

Do I think making those drugs legal and purchasable over the counter would make the situation better or worse? Worse, much worse.

Re:Suspected head of $21B crime syndicate may be world’s mos... by TylerE on Tuesday November 02, 2021 @11:45PM (#29090911)
Really?

From where I'm sitting, the major negative externalities are overdose deaths' (which are mostly for spiked doses/things not not being what they claimed) and gang activity.

Legalization makes both of those go away.