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Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @05:16PM (#27090775)
As someone 99% confident that we're on the verge of discovering a way of reversing aging, it makes me incredibly sad, almost angry, to realize that many people are literally planning how they'll die.
Re:People who live past 105 years old have genes that stop D... by lamontcg on Saturday May 08, 2021 @07:06PM (#27091624)
> we're on the verge of discovering a way of reversing aging

This happens shortly after Tesla makes the million full self driving robotaxis at the end of 2020?

Re:People who live past 105 years old have genes that stop D... by hellotomyrars on Saturday May 08, 2021 @05:40PM (#27090982)
Even if we discover the secret to everlasting life there are going to be plenty of people who would like to die eventually. Also if I’m 90 and in poor health the idea of living forever doesn’t sound very appealing in general.

I think your premise is incredibly ambitious but even if it’s true the vast majority of people aren’t going to get access to the veritable fountain of youth anyways, at least not for a very long time because society will have to fundamentally change both to accommodate the idea and also to allow your average person to have the means to obtain it.

Re:People who live past 105 years old have genes that stop D... by orangecat on Saturday May 08, 2021 @06:42PM (#27091458)
and also to allow your average person to have the means to obtain it

It's basically the opposite. Health care for old people is very expensive, precisely because they're old. Reversing or preventing aging to the point where everyone has the health profile of a 30 year old would save a fortune.

Re:People who live past 105 years old have genes that stop D... by hellotomyrars on Saturday May 08, 2021 @07:20PM (#27091704)
I won't contend the point you're making regarding the costs of healthcare for population that is healthier on average vs one that isn't (elderly). That's true.

The idea that our collective human society is going to be handing out everlasting life to anyone who wants it is, even in light of this, something I can't begin to fathom. Perhaps if the arrival of the immortality drug also coincides with the arrival of a utopian society that actually cares about people beyond their basic (and incredibly power-imbalanced) economics that are skewed to benefit corporations not only over people, but over governments, then I can accept it.

But in context of the way the world currently works, this is an incredibly optimistic or naïve assertation to me. People die every day even in the most developed nations due to a lack of access to healthcare, food and/or shelter.

Re:People who live past 105 years old have genes that stop D... by true_religion on Saturday May 08, 2021 @05:49PM (#27091066)
If you are 90 and in poor health, it's likely because you are dying albeit slowly. The technology for everlasting life will likely reverse or halt the breakdown of basic bodily functions due to 'old age' and may rejuvenate organs who are simply suffering from maintenance issues.

So in the end, a cure for death is also a cure for myriad amount of ailments.

Re:People who live past 105 years old have genes that stop D... by hellotomyrars on Saturday May 08, 2021 @06:09PM (#27091209)
Maybe. This is speculation on speculation.

It certainly makes a lot more sense for people to plan their lives around our current understanding of mortality than an increasingly hard to believe pyramid of hypotheticals as the GP has contended.

Re:People who live past 105 years old have genes that stop D... by adrianN on Sunday May 09, 2021 @12:14AM (#27093177)
The speculation is very convincing, it goes like this: 1) Senescence is a collection of symptoms caused by incomplete repair mechanisms allowing damage to build up, 2) some level of damage has very little ill effects (e.g. the amount you've collected on your 25th birthday), and 3) there are interventions that stop the accumulation of damage or even reverse it.

I believe currently only 3) is a bit controversial, but since there are biologically immortal organisms I find it plausible that it's possible.

Re:People who live past 105 years old have genes that stop D... by robwwilliams on Saturday May 08, 2021 @08:35PM (#27092088)
The current best treatment for death is to contribute to social health and knowledge. Transmit both to your progeny and younger colleagues. Your particular atoms and molecules are really not all the unique and wonderful.
Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @08:44PM (#27092145)
Your atoms and molecules might not matter, and indeed get replaced many times as a normal process throughout your life, but your consciousness is wonderful and valuable.
Re:People who live past 105 years old have genes that stop D... by lamontcg on Saturday May 08, 2021 @07:04PM (#27091609)
> So in the end, a cure for death is also a cure for myriad amount of ailments.

Not if you're an amputee. There's a certain amount of damage to the body that isn't due to just aging.

Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @07:07PM (#27091632)
Google Michael Levin or watch his lectures here: https://www.youtube.com/playlist?list=PLLvA7pB41pDk27XOjqbXi...

We'll probably figure out how to regrow limbs and organs soon.

Re:People who live past 105 years old have genes that stop D... by lamontcg on Saturday May 08, 2021 @07:21PM (#27091715)
Full Self Driving soon?
Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @07:27PM (#27091748)
Lol. It should be easy to make a self-driving car that would coordinate its actions with surrounding self-driving vehicles. It's extremely hard to make it behave well in an environment where some of the cars are driven by humans.

So, no, not soon. Unless we introduce dedicated lanes where only self-driving cars are allowed.

Re:People who live past 105 years old have genes that stop D... by krapht on Sunday May 09, 2021 @12:51AM (#27093318)
When is the singularity going to happen?
Re:People who live past 105 years old have genes that stop D... by lamontcg on Sunday May 09, 2021 @06:17PM (#27100337)
2012. We're all machine elves now.
Re:People who live past 105 years old have genes that stop D... by hhjinks on Saturday May 08, 2021 @08:08PM (#27091971)
That's just egocide. We've had plants that do that for millennia.
Re:People who live past 105 years old have genes that stop D... by jtchang on Saturday May 08, 2021 @05:34PM (#27090927)
The societal ramifications of a large number of people living past 100 would be unprecedented.
Re:People who live past 105 years old have genes that stop D... by bspammer on Saturday May 08, 2021 @05:44PM (#27091021)
They certainly will be, but not necessarily for the worse. Imagine oil billionaires having to live through the consequences of their actions. Imagine the societal benefits of people being able to use their decades of valuable experience for much longer, rather than having it die with them.

I do believe it’s going to happen, but personally I’m more pessimistic than GP and don’t think it’ll be within my lifetime. Medical research is so tightly regulated when it comes to testing on humans (for good reason!), and there isn’t enough money going into the field.

Re:People who live past 105 years old have genes that stop D... by SamoyedFurFluff on Saturday May 08, 2021 @07:18PM (#27091696)
> Imagine oil billionaires having to live through the consequences of their actions.

They won’t be. They’ll be billionaires, able to buy any scarce resource they need to continue their lifestyle. They might need to cut back on their monthly yacht purchase, maybe, but little else.

Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @05:48PM (#27091058)
That's one way to look at it.

Another is that this is the endgame for medicine as there is no other path forward. A huge amount of resources, both human and monetary, is spent to care for elderly people to slow the decline of their fragile health as much as possible — while still inevitably failing eventually. It's as if we've almost hit the ceiling of what can be done here with "traditional" methods. So it's the next logical step to declare aging itself a disease, because it's ultimately the cause of all those conditions, and start looking for the ways to reverse and/or prevent it.

Re:People who live past 105 years old have genes that stop D... by ben_w on Saturday May 08, 2021 @05:55PM (#27091100)
I can say that about dozens of technologies that already exist, and several others besides a mere 18 year boost to average life expectancy that are actively being worked on.
Re:People who live past 105 years old have genes that stop D... by robwwilliams on Saturday May 08, 2021 @08:31PM (#27092070)
We would all be wise to plan along these lines until your 99% sure-thing is proved. I study the genetics of longevity and alas I am gracefully planning to die.
Re:People who live past 105 years old have genes that stop D... by katzgrau on Saturday May 08, 2021 @09:52PM (#27092452)
My guess is that everlasting life will just open the door to other problems we didn't consider.

Fix one bug, say hello to another.

Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @10:47PM (#27092748)
We'll fix them as we encounter them. At some point the human body will be completely reverse engineered anyway.
Re:People who live past 105 years old have genes that stop D... by katzgrau on Sunday May 09, 2021 @07:27AM (#27095120)
Yeah the next issue will be obvious and have an easy solution. And the distinction between fixing a bug and breaking a feature will always be clear :) /s
Re:People who live past 105 years old have genes that stop D... by tasty_freeze on Saturday May 08, 2021 @06:45PM (#27091475)
A few counter thoughts:

* I love peppermint ice cream, but I'd probably get tired of it after a million gallons.

* I'm looking forward to retirement in a few years. I don't desire to work for 5000 years.

* A thing in infinite supply has little value. Why would another year of life be any different?

* Marriages would become limited term contracts, and partners would change every few decades

* Unless society figures out a way to address poverty, do you think the billions of impoverished people will want to live forever?

* Having children will be limited to a chosen few, probably the wealthiest.

* Suicide will have to become socially acceptable when people become

Honestly, I think even if the technology is developed, it will be available only to the rich and powerful. They would be willing to prevent the technology from becoming widely available because it would upset the current order and they dare not risk losing their position of privilege.

Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @06:58PM (#27091564)
It's nice to have an option to not age and die, anyway. We have no idea what the world will be like in a decade, let alone 5000 years.

> I love peppermint ice cream, but I'd probably get tired of it after a million gallons.

So you'll take a break. Then you'll crave some more. The problem with suicide is that one can't change their mind, because there's no mind any more.

> A thing in infinite supply has little value. Why would another year of life be any different?

We have effectively unlimited supply of water, yet it has a lot of value to us because a person can't survive without water.

Re:People who live past 105 years old have genes that stop D... by oblio on Saturday May 08, 2021 @07:08PM (#27091640)
* People don't like changing their minds once they find something that works so we'll have huge chunks of people with moral compasses from hundreds of years ago
Re:People who live past 105 years old have genes that stop D... by bobmaxup on Saturday May 08, 2021 @10:49PM (#27092759)
There are many different forms of aging. Which one are we on the verge of reversing and how?
Re:People who live past 105 years old have genes that stop D... by anotha1 on Saturday May 08, 2021 @05:26PM (#27090862)
What makes you so sure? Personally, that bubble burst for me a long time ago. I hope I'm wrong. I'd love a new insight or even any tips that might give me more of a chance to see that discovery.
Re:People who live past 105 years old have genes that stop D... by pengaru on Sunday May 09, 2021 @01:43AM (#27093543)
As someone who is literally the only surviving member of my childhood block's clique of 80s boys, I laugh loudly in your general direction.
Re:People who live past 105 years old have genes that stop D... by andrewjl on Sunday May 09, 2021 @02:03AM (#27093624)
I'm a strong supporter of this sort of research but our lack of fundamental understanding of most life processes does not inspire confidence we'll crack this puzzle soon.

More likely, through use of bioinformatics to customize chronic disease treatments, we'll get another few decades of average life expectancy over the next century.

Re:People who live past 105 years old have genes that stop D... by xwdv on Saturday May 08, 2021 @05:30PM (#27090890)
We are going to die and never come back, 100%.
Re:People who live past 105 years old have genes that stop D... by schnebbau on Saturday May 08, 2021 @05:24PM (#27090847)
Do you have sources or reading material to substantiate your confidence? I'm interested in this area.
Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @05:32PM (#27090908)
1. https://old.reddit.com/r/longevity/

2. https://joshmitteldorf.scienceblog.com (be sure to follow the links to research papers and read the comments)

3. I also made a playlist with videos and lectures on the topic: https://www.youtube.com/playlist?list=PLLvA7pB41pDk27XOjqbXi...

Re:People who live past 105 years old have genes that stop D... by neonological on Saturday May 08, 2021 @07:10PM (#27091650)
I'm sorry but this is extremely weak none of this brings it anywhere close to 99%. This is youtube, a blog and reddit. Seriously.
Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @08:03PM (#27091950)
So? There are links to real research papers written by real scientists.
Re:People who live past 105 years old have genes that stop D... by Google234 on Saturday May 08, 2021 @08:16PM (#27091997)
Why do you think we can cure aging when we haven’t solved or even made any progress tackling much simpler problems like Alzheimer’s?
Re:People who live past 105 years old have genes that stop D... by robwwilliams on Saturday May 08, 2021 @08:45PM (#27092152)
Grishka needs to read more widely on this topic. Start with Caleb E. Finch’s magisterial book “Longevity, Senescence, and the Genome” (University of Chicago Press, 1990). Or read my review with Michael Hook: “Genetic Cartography of Longevity in Humans and Mice: Current Landscape and Horizons”.

Just do a text string search. It is on PubMed Central and free.

Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @08:31PM (#27092071)
They are not "much simpler" — they're direct consequences of aging. It's like trying to put a fresh coat of paint on a car that has almost rusted through. It makes more sense to address the root cause than its many consequences.
Re:People who live past 105 years old have genes that stop D... by fighterpilot on Saturday May 08, 2021 @05:47PM (#27091051)
Imagine the misfortune of being 80 years old when humanity finally figured out how to do this.
Re:People who live past 105 years old have genes that stop D... by true_religion on Saturday May 08, 2021 @05:50PM (#27091071)
I think the worst would be discovering that we can cure old age but only in utero, thus the next generation will be the immoral ones but we will all die eventually.
Re:People who live past 105 years old have genes that stop D... by notahacker on Saturday May 08, 2021 @06:32PM (#27091401)
The worst would be discovering we can cure old age, but only for people rich enough to pay for the extraordinarily expensive treatment...
Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @05:53PM (#27091090)
No, imagine the fortune because you'll now have your body reverted to a younger age.
Re:People who live past 105 years old have genes that stop D... by fighterpilot on Saturday May 08, 2021 @05:57PM (#27091112)
Touche.

If it's possible do you know why evolution didn't figure out how to do this? Seems like it would be a good adaptation

Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @06:08PM (#27091205)
This one is easy. First of all, evolution only cares about the species as a whole, so the survival of an individual, especially after they've produced their offspring, doesn't matter much. Second, in the wild, animals will be killed by predators much more quickly than they'd die of old age, so all the mutations that only manifest negatively in older age have never had a chance to be selected against.

Besides, the whole premise of evolution is that older generations die.

(disclaimer: I'm a software developer, not a biologist, but I'm fascinated by biology)

Re:People who live past 105 years old have genes that stop D... by I-M-S on Saturday May 08, 2021 @06:42PM (#27091460)
You got it in reverse: evolution only "cares" about the individual

https://en.wikipedia.org/wiki/The_Red_Queen:_Sex_and_the_Evo...

Re:People who live past 105 years old have genes that stop D... by robwwilliams on Saturday May 08, 2021 @08:52PM (#27092177)
Lol. I usually read HN to follow tech trends. This thread in hilariously uninformed. It is as shaky as me writing a critique of database engines would be.

On this specific subthread: yes the individual is the level of selection (mainly) but Dawkins has renewed interest in the sequence variant as the ultimate unit of selection. We are protoplasmic bags of gene variants, some of which make it to the next generations.

Re:People who live past 105 years old have genes that stop D... by yosito on Saturday May 08, 2021 @06:16PM (#27091271)
Evolution optimizes for reproduction, not long life. Long life is likely not very beneficial to reproduction and a large population of older members is a drain on resources. At least, it was until we got to the Information Age.
Re:People who live past 105 years old have genes that stop D... by joak on Saturday May 08, 2021 @08:48PM (#27092162)
Sometimes long life is key to reproduction, for example old turtles are bigger and safer from predators (before humans came) and have more offsprings than younger ones (yearly and in total). Turtles can grow very old because there is reproduction advantage to that.
Re:People who live past 105 years old have genes that stop D... by Jach on Sunday May 09, 2021 @12:23AM (#27093223)
For a counterpoint to the confidence, but still a very high-confidence prediction, Aubrey de Grey has recently estimated a 50% chance that we'll hit longevity escape velocity by 2036. That is, enough treatments will be available to people such that they can expect their lifespans to be Y, an increase from their previous X. But before they hit Y age, there'll be new treatments developed they can take that extend expected life age even further to Z, and so on, until we arrive at general treatments that extend life indefinitely.

Aubrey is the foremost expert in the whole field of longevity research as far as I'm concerned, so I don't have any reason to be more or less confident than him about any aspect of it. If you haven't read it, his Ending Aging book covers a lot of details. It was published in 2007 but has still held up, especially with overall strategy. Apart from the various medical developments since then, another encouraging sign is the increase in newly formed companies in the space, lowering the need for philanthropy/government grants. https://agingbiotech.info/ has a list

Re:People who live past 105 years old have genes that stop D... by chias on Saturday May 08, 2021 @06:59PM (#27091568)
I like to imagine that this is what cells think right before they become cancerous.
Re:People who live past 105 years old have genes that stop D... by crimson_chin on Saturday May 08, 2021 @05:23PM (#27090829)
Is that new? Humans have always planned how they die, and how it will affect those around them. Isn't that the point of a will, for instance?
Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @05:35PM (#27090943)
Idk, I just don't understand the meaning of a life that has an end, and thus "leaving something behind" makes no sense to me. Why leave something behind if the moment a person dies the entire universe ceases to exist for them?
Re:People who live past 105 years old have genes that stop D... by jlokier on Saturday May 08, 2021 @06:01PM (#27091158)
It makes sense if you believe other people exist in a meaningful way similar to your own conscious existence. When you die, the universe doesn't cease to exist for them. So you are not leaving things behind for your own benefit. It's for other people.

Conversely, if you believe the universe ceases to exist entirely when you die, you believe other people cease to exist too. In this case, perhaps the only consistent way to think of other people is that they are not like you when you are alive either.

From a more down to Earth perspective, if I left the planet on a one-way interstellar FTL journey, confident I would never return and that there was no way to communicate with the people I left behind, even though it would be a relief in some ways and I'd stop caring about people left behind, I'd still want to arrange good things for some of them after my departure. Because I'm nice like that.

Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @06:25PM (#27091337)
> From a more down to Earth perspective, if I left the planet on a one-way interstellar FTL journey, confident I would never return and that there was no way to communicate with the people I left behind, even though it would be a relief in some ways and I'd stop caring about people left behind, I'd still want to arrange good things for some of them after my departure. Because I'm nice like that.

Well, you can't be so sure you'll never see them again and you'll never be able to communicate with them, because of scientific advances and such. The only truly irreversible thing that could happen to a human being is death itself. Everything else being reversible (or eventually reversible) is the nice part about being alive.

Re:People who live past 105 years old have genes that stop D... by fallingfrog on Saturday May 08, 2021 @07:21PM (#27091712)
Well, the universe doesn’t need me to keep on going, and it makes me happy while I’m alive that I can help my fellow humans out.

That doesn’t really work out in a logical sense if you assume that people are purely self interested, but they aren’t, their behavior is optimized by evolution and self interest is only one of many complicated feelings that people have.

I still share your optimism though that we might cure the diseases of aging, so that people do not suffer from slow decline.

Re:People who live past 105 years old have genes that stop D... by pizza on Saturday May 08, 2021 @05:53PM (#27091086)
There are things worse than dying, similarly, there are things that are better than what can be experienced
Re:People who live past 105 years old have genes that stop D... by balfirevic on Saturday May 08, 2021 @06:16PM (#27091273)
If you had to bet, what would you say is the percentage of people that are currently planning how to die but are doing so in vain?
Re:People who live past 105 years old have genes that stop D... by spiderice on Saturday May 08, 2021 @05:23PM (#27090836)
May I ask why you are so confident? Sounds very sci-fi, though I’d love for it to be true.
Re:People who live past 105 years old have genes that stop D... by donio on Saturday May 08, 2021 @06:18PM (#27091290)
How foolish. May you live forever is how I would curse my worst enemies.
Re:People who live past 105 years old have genes that stop D... by neonological on Saturday May 08, 2021 @07:23PM (#27091727)
How is it logical to know living forever is bad when you there isn't a single person on the face of the earth who has done so? This is not a rational statement or philosophy. It is simply speculation as we have no evidence whether this is good or bad unless we talk to someone who has experienced it. Fundamentally speaking... no one has experienced this so we have no evidence FOR or against it.

Additionally "living forever" isn't invulnerable immortality where you are doomed to float around alive in the solar system long after the sun has inflated and pulverized the earth as a red giant... You'll still die well before that.

You can also always choose when to kill yourself, whenever. Logically any form of "living forever" described as a scientific possibility is actually more of a "you can choose when you die" or a "you can live much longer than normal"

Re:People who live past 105 years old have genes that stop D... by donio on Saturday May 08, 2021 @10:09PM (#27092553)
If you are asking to live as long as you desire, I am all for that! But the comment I was replying to was ridiculing the idea of planning for the eventual end of one's existence so presumably they want to live literally forever. And that's a very long time.

For arguments sake imagine that your consciousness is transferred into a simulation that runs at a highly accelerated rate so you can experience a very long existence. The custodian of the simulation is benevolent, it tries to keep you happy, lets you shape the world in whatever way you want but the one hard rule is that you are not allowed to end.

You will probably have an awesome time for the first few hundred years. So many fun experiences you could only dream of before. You can explore the stars, turn the world into paradise, come up with new forms of art that no one has imagined.

After a few thousand years things might start getting a bit samey but you will still find new things to do. But how about after a few million years? Or billion? It might start getting pretty boring. You have done all the fun things countless times and all the terrible things too just to do something different. But your looooong adventure is only beginning! There is no exit button. Welcome to hell.

The scenario is not completely implausible, agreed? I think one of the Iain M Banks novels had something similar going on. I think the custodian there was evil but I am arguing that on the looong run that makes little difference.

One might argue that they would transform themselves into something that can tolerate the infinite existence but I call that cheating, such a thing wouldn't really be you anymore. And the custodian might see it that way too.

Re:People who live past 105 years old have genes that stop D... by neonological on Sunday May 09, 2021 @03:27PM (#27098925)
First off nobody realistically talks about this. It's speculation. The topic at hand is talking about endeavors in the realm of reality. Not even mountains can last billions and billions of years, nobody is talking about immortality at that scale simply because it won't ever happen.

So if we're speculating here your argument is that boredom is a curse. At my age I'm already bored every single day of my life.

I'd rather be bored than be dead. But again this is speculation. I'd rather be bored for 50 years than die at 50 but would I be the same at 5 billion? Truthfully nobody knows. Even 50 Years is a long time to be bored but if you're not bored at 50 what makes you suddenly conclude that 5 billion is too much?

There's no evidence or weight behind this philosophy. Boredom does not equate to being cursed.

Re:People who live past 105 years old have genes that stop D... by Jach on Sunday May 09, 2021 @01:01AM (#27093359)
Pretty much no one who advocates for effective biological immortality also argues that you should be forced to live forever against your will. So while it can be fun to speculate on such, as it can be fun to look at torture methods (the video game Amnesia has a good section on this), it shouldn't be mistaken for people advocating for such.

The ridicule the comment made is for a mindset that actually happens right now, talk to some retired boomer relatives. A lot of them have had actuarial consultations and some of those are treating it almost like gospel, like the other comment wishing he could do the same given 23andMe reporting. This leads to them depleting their savings (mostly held up in "safe" investments that aren't expected to grow or shrink much over the relevant timespan) at some rate so that it gets close to $0 by the time they can expect to die. Some older people have already made it long enough to go past that point, and they get into the same situations that retirees without any savings get into. i.e. you hear about old ladies subsisting on dog food because their only source of income is a small social security check.

A better mindset is the one used by the FIRE crowd, which applies just as well if you're "retired" at 30 or 60: recognize index funds are not just pretty safe but also give a pretty high confidence minimal rate of return, plan for average x% returns per year, and don't withdraw more than x% for income, so that your savings never decreases but in fact increases. This way you can retire whenever your savings hits the right number to support your required income indefinitely, rather than retiring when your savings hits the right number to provide income only for the next X years until you die.

(I shouldn't have to say it but will: this is a theoretical optimal modeling strategy, reality will be messier, any real plan should analyze possible setbacks and ways to deal with them -- the easiest way typically being to seek work again for some period of time, which tends to be easier the more biologically young you are. And of course, regardless of biological immortality or whatever, you could be an unlucky passenger in a car driving down the freeway when a random brick from a truck in the oncoming lane comes loose and collides with your head.)

Re:People who live past 105 years old have genes that stop D... by katzgrau on Saturday May 08, 2021 @10:10PM (#27092558)
Yep, there also won't ever be a person who lives forever, since one can only observe someone who has lived for a finite amount of time.

But whether it's good or bad is something that only an individual can determine. It's more/less along the same lines as the question "is life worth living?"

Re:People who live past 105 years old have genes that stop D... by DennisP on Saturday May 08, 2021 @09:46PM (#27092423)
If you decide you don't like it, take up wingsuit jumping. You'll likely die before that long and enjoy your remaining time, so win-win.
Re:People who live past 105 years old have genes that stop D... by donkarma on Saturday May 08, 2021 @08:38PM (#27092106)
Agreed? Why are people so afraid of death? If you're religious, then you wouldn't want to live forever. If you think you just disappear into the void when you die, then it doesn't matter when you die (which you will eventually).
Re:People who live past 105 years old have genes that stop D... by DennisP on Saturday May 08, 2021 @09:47PM (#27092430)
Who says they're afraid? Maybe some people just enjoy life.
Re:People who live past 105 years old have genes that stop D... by AuryGlenz on Sunday May 09, 2021 @12:10AM (#27093157)
I don’t know why people refuse to admit it. I’m afraid to die. Not of the process, but of not existing.

So is pretty much every other creature. We all try to avoid death.

Re:People who live past 105 years old have genes that stop D... by grishka on Saturday May 08, 2021 @07:02PM (#27091593)
So how do I become your enemy? :D
Re:People who live past 105 years old have genes that stop D... by JohnJamesRambo on Saturday May 08, 2021 @06:40PM (#27091452)
Curse me then.
Re:People who live past 105 years old have genes that stop D... by SvenMarquardt on Saturday May 08, 2021 @05:20PM (#27090811)
If we can reverse ageing, your entire life will be spent planning how to avoid existential risks. When you can live forever even crossing the road becomes too risky.
Re:People who live past 105 years old have genes that stop D... by ben_w on Sunday May 09, 2021 @04:39AM (#27094318)
Not necessarily, because people do plenty of risky activities today which shorten their life expectancies.