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Re:FDA Approves First Oral Treatment for Postpartum Depression by roody15 on Tuesday August 08, 2023 @08:18PM (#37057216)
Postpartum Depression holistic patient view versus commercial pharmaceutical treatment.

The shear emotional, physical and life changes involved in having a baby is in many ways similar to PTSD. In just a few weeks your body has been physically exhausted, your mentally and emotionally drained and now you are physical/spiritually/ and emotionally bond to a new human life who is 100 percent dependent on you for its survival and well being.

Now imagine this leads to a period of depression in the patient. Is this really a pharmaceutical issue or a societal structure and support issue. Perhaps even more than just that.

It is depressing to me to see things like this get pushed out … just take this pill and it will help move you up a few points on our 17 point scale and cope.

Instead of wow, let’s really look at what’s happening with the birthing process on how we prepare mothers and support them emotionally, physically and maybe even spiritually.

Nope just take this drug and in 6 weeks you will be back to work and we can get that new kid in daycare :/

#rantover

Re:FDA Approves First Oral Treatment for Postpartum Depression by fasterik on Tuesday August 08, 2023 @08:39PM (#37057355)
Nobody is forcing anybody to take depression medication. The fact that it's there for people who are suffering and feel that they need it is a good thing. True, depression is a complex phenomenon, and I don't think any good doctor or psychiatrist would deny that you need social and emotional support in addition to medication. However, antidepressants seem to be a useful tool for a lot of people to manage the symptoms to a point where they can function well enough to make the necessary holistic changes. If you've ever experienced depression, you'll know how hard it can be to just get out of bed, go grocery shopping, or run a mile. Add that on top of the stresses of being a new parent and I imagine it can be extremely difficult.
Re:FDA Approves First Oral Treatment for Postpartum Depression by roody15 on Tuesday August 08, 2023 @09:03PM (#37057527)
Agree with this statement wholeheartedly. Antidepressants can help many feel better and help get things moving and enable the person to make even more life changes to get even better.

#personalexperience

Re:FDA Approves First Oral Treatment for Postpartum Depression by herrschnapps on Tuesday August 08, 2023 @08:36PM (#37057338)
My wife suffered from PPD after the birth of our first. She also suffered antenatal depression during her second pregnancy.

SSRIs literally saved her life.

The difference to her personality was profound: the woman I knew and loved came back.

Was it a societal structure and support issue? No. She had support from myself, our families, our GP and a psychologist. My work provided me with paid time off to manage it. We had no financial concerns; she had 12 months of legally protected maternity leave with the first 6 months fully paid.

She was ill and the medication worked.

Re:FDA Approves First Oral Treatment for Postpartum Depression by pc86 on Tuesday August 08, 2023 @08:34PM (#37057323)
The chemistry of your brain literally changes, so yes, it's an issue that pharmaceuticals can help with tremendously. I am often the first person to rail against overprescribing of medication, particularly psychiatric medication, but this is categorically a Good Thing. And nothing in the article suggests this is anywhere close to a "just take this pill" type of treatment. This is part of a holistic treatment plan.

All that being said, if you want spiritual support go to your church, you shouldn't be getting that from your OB or pediatrician.

Re:FDA Approves First Oral Treatment for Postpartum Depression by marginalia_nu on Tuesday August 08, 2023 @10:12PM (#37057959)
The brain is an electrochemical machine. Your brain chemistry changes when you're happy, sad, hungry, sad, angry, bored, horny, sleeping; pretty much every human experience is mediated through brain chemistry changes.
Re:FDA Approves First Oral Treatment for Postpartum Depression by pc86 on Wednesday August 09, 2023 @08:18AM (#37061522)
And in any other machine when something breaks you fix it. If your rotator cuff gets torn you don't say "just stop having shoulder pain" or "shoulder is a natural part of the process of life and you have to deal with it," you go to a PT, maybe have surgery, maybe even take a pill or two.

If you think PPD (or any other form of depression) is "brain chemistry" on the same level and getting hungry or horny you grossly misunderstand what depression is at a fundamental level.

Re:FDA Approves First Oral Treatment for Postpartum Depression by marginalia_nu on Wednesday August 09, 2023 @09:12AM (#37062163)
Well it is and it isn't.

The serotonin imbalance hypothesis of depression, widespread as it is in popular culture, has actually been pretty thoroughly debunked at this point[1]. We know that SSRIs do have a therapeutic effect, but it seems their effect is oddly enough unrelated to serotonin levels.

What they seem to do is mask the depressive symptoms to the point where you're given a sporting chance to "behave" less depressed, which is what seems to be the most effective treatment. It's fairly analogous to how painkillers can cure back pain by permitting you to move around more.

Not acting like you're depressed is the real cure, which is of course very cruel, because as anyone who has had a depressive episode will attest to, just getting out of bed may be a struggle.

[1] https://www.nature.com/articles/s41380-022-01661-0

Re:FDA Approves First Oral Treatment for Postpartum Depression by CoastalCoder on Tuesday August 08, 2023 @08:27PM (#37057286)
> Is this really a pharmaceutical issue or a societal structure and support issue.

This seems like a weak criticism. You're vaguely referring to some other hypothetical solution that may or may not exist.

There may be a case for a two-pronged approach, but why complain about the prong that just got approved?

Re:FDA Approves First Oral Treatment for Postpartum Depression by nocoiner on Tuesday August 08, 2023 @08:26PM (#37057284)
Ah yes. The good ol’ “Well, have you tried not being depressed?” Works every time.
Re:FDA Approves First Oral Treatment for Postpartum Depression by sixo on Tuesday August 08, 2023 @08:50PM (#37057429)
OP said nothing of the sort. They clearly described a dysfunction in the surrounding support structure, not the mother herself.
Re:FDA Approves First Oral Treatment for Postpartum Depression by jncfhnb on Tuesday August 08, 2023 @08:56PM (#37057474)
Yeah but like, fuck that. It’s not a duality of support structure fault or mother fault.

It can also be mother’s problem and nobodies fault.

Re:FDA Approves First Oral Treatment for Postpartum Depression by ceejayoz on Tuesday August 08, 2023 @11:42PM (#37058458)
People with very strong supports still get postpartum depression.
Re:FDA Approves First Oral Treatment for Postpartum Depression by j45 on Wednesday August 09, 2023 @12:02AM (#37058557)
Lots of people became parents suing pandemic lockdowns and didn’t really have a choice or say in surrounding support structures being available or possible.
Re:FDA Approves First Oral Treatment for Postpartum Depression by pc86 on Wednesday August 09, 2023 @08:19AM (#37061533)
Which is itself completely irrelevant because support structures or lack thereof don't have anything to do with PPD in any way. Plenty of people with amazing support in their family and community end up with crippling PPD. Plenty of people with zero support don't have the slightest bit of PPD. It's irrelevant.
Re:FDA Approves First Oral Treatment for Postpartum Depression by j45 on Wednesday August 09, 2023 @01:59PM (#37066343)
How is it completely irrelevant? I think you might not know as much as what you're talking about. And/or be out of date. I'm normally don't reply to posts that contain petulant dismissal and minimization of others.

Knowing how there is a much larger silent group who is reading and might disagree with you, or how your words will actually do harm to deny a mother what she may be going through.

It's up to you, but I hope you read the below with an open mind and eyes.

Isolation in a pandemic CAN make PPD worse.

The rates of PPD during the pandemic WERE much higher, and from what the data is saying more intense.

Imagine: Becoming a mother alone in a hospital room, without a single woman figure in the family who exists and would have been present otherwise is very easily a magnifier and amplifier of any conditions. Some mothers had to enter the hospital for weeks before birth alone from complications.

No visitors allowed, or only one. No support people allowed. Hospitals also had shut down most of the pre-natal and ante-partum programs and check-ins with dieticians, other parents to be, etc.

It was pretty much solitary confinement, and dismissal of it for those parents who went through it is pretty surprising since you seem to be an authority on what does or doesn't make PPD symptoms or experiences worse. It just kind of shows how out of touch your position might actually be.

So, onto the logical proof of explaining something that will only exist once science has studied it for your logical brain.

1) "Pandemic isolation is leading to more postpartum depression, anxiety. Everything that we tell postpartum women to do, like connect to other people, get out of the house, establish a routine, they can’t do that.”

https://www.today.com/parents/covid-19-pandemic-leads-more-p...

2) "A third of new moms had postpartum depression during early COVID.

People who delivered babies during the pandemic also reported more distress and anxiety. ... One in three new people who had babies in the beginning of the pandemic experienced postpartum depression – potentially triple pre-pandemic levels – while one in five had major depressive symptoms, according to research led by the University of Michigan School of Nursing and Michigan Medicine."

https://www.michiganmedicine.org/health-lab/third-new-moms-h...

3) "New moms, experts worry about postpartum depression during COVID-19 as services cut back Many in-person services now being offered by phone, video or have been cancelled altogether"

https://www.cbc.ca/news/canada/windsor/postpartum-depression...

4) "Women who lack social support after the birth of a baby are more likely to develop postpartum depression."

https://bmcpregnancychildbirth.biomedcentral.com/articles/10...

5) "We believe the present study to be the first to demonstrate that fewer supportive persons during pregnancy is a predictor for postpartum depression. This finding points to the benefits of early intervention to increase the number of support providers for pregnant women19."

I hope this helps with undertaking a search yourself to learn more about PPD.

As an aside, it's questionable if there's a reason you feel it's acceptable to harshly dismissing the words of strangers as harshly as you might with your own inner dialogue? The world's eyes and ears are not a toilet for you.

As for support structures having nothing to do with PPD, I can only speak to what I've witnessed and what the doctors in our lives have pointed out.

Since you weren't there, and it might not exist for you unless you can understand it, it's pretty easy to search for topics on the internet these days.

Re:FDA Approves First Oral Treatment for Postpartum Depression by pertymcpert on Wednesday August 09, 2023 @02:36AM (#37059387)
PPD can't be fixed by support structures.
Re:FDA Approves First Oral Treatment for Postpartum Depression by patmorgan23 on Tuesday August 08, 2023 @08:58PM (#37057484)
That's not what they're saying at all.

They're saying we should make sure expecting mothers are well informed on the effects pregnancy and birth has on their body. Not give them unrealistic expectations that pregnancy will be easy and that everything will go back to being the same after they give birth. A miss match in expectations can help drive someone into depression. Prevention by supporting new mother's.

I think they go too far though. Everyone's situation is different not all depression is preventable, many people need SSRI and other oral treatments. But let's not throw strawmen around.

Re:FDA Approves First Oral Treatment for Postpartum Depression by refurb on Tuesday August 08, 2023 @09:49PM (#37057815)
That's not what they're saying at all.

That's exactly what they are saying. "If these women just had more support they wouldn't be depressed".

That's not how postpartum depression works at all.

Re:FDA Approves First Oral Treatment for Postpartum Depression by khazhoux on Wednesday August 09, 2023 @12:53AM (#37058836)
> Not give them unrealistic expectations that pregnancy will be easy and that everything will go back to being the same after they give birth

Do you really think that expectant mothers are so naive as to think that pregnancy and birth and keeping a newborn alive will be easy?

Re:FDA Approves First Oral Treatment for Postpartum Depression by standardUser on Tuesday August 08, 2023 @08:47PM (#37057405)
I don't see it. We know people in the past were much more willing to suffer quietly, if not required to do so. And we know the damage that causes down the line. What I see is another in the endless examples of society finally letting people out of the hype-narrow boxes of acceptable behaviour and experiences and listening to what they have to say as who they are, not what cruel and ancient conventions demand they should be.
Re:FDA Approves First Oral Treatment for Postpartum Depression by ksenzee on Tuesday August 08, 2023 @09:14PM (#37057605)
If you are not a researcher, or a physician, or some other expert, and if you have not given birth yourself, please don’t throw out this kind of ill-considered opinion. Post-partum depression (and anxiety for that matter) is more severe than just the effects of sleep deprivation and lack of support. Anything we can do to treat it, even partially, is worth doing.
Re:FDA Approves First Oral Treatment for Postpartum Depression by rrrrrk on Tuesday August 08, 2023 @11:12PM (#37058295)
Well, tell me if you please, what is this research that was done by physician? Is there a known physical source of said depression? Or we know that there is a certain hormone that secrets in ones body to cause this depression?

> Anything we can do to treat it, even partially, is worth doing.

A very dangerous attitude if one is concerned with a human body. You don't have any idea what is going on and you going to throw in something with side effects of hitting a poor woman with a brick in a face.

Just be a man, be there and help her to get thru it. Birth is not a newest fab of 2023. It was around since the dawn of man (citation required). And for hundreds of thousands of years one would not use drugs. Suddenly we are going to change it. I beg you.

It's like re-writing a perfectly working golang server in NextJS just cause you love microservices.

Re:FDA Approves First Oral Treatment for Postpartum Depression by gmerc on Tuesday August 08, 2023 @11:40PM (#37058448)
Only a man could write this.
Re:FDA Approves First Oral Treatment for Postpartum Depression by saagarjha on Wednesday August 09, 2023 @12:02AM (#37058560)
It is generally rare that Hacker News comments make me physically cringe. This is, unfortunately, one of those times.
Re:FDA Approves First Oral Treatment for Postpartum Depression by ksenzee on Wednesday August 09, 2023 @11:52AM (#37064537)
The fact that I’m a woman (who has given birth and had PPD, twice) gives it that extra je ne sais quoi.
Re:FDA Approves First Oral Treatment for Postpartum Depression by saagarjha on Wednesday August 09, 2023 @06:56PM (#37069497)
Have you considered just being a man?
Re:FDA Approves First Oral Treatment for Postpartum Depression by moomoo11 on Tuesday August 08, 2023 @11:32PM (#37058406)
Ew why would someone even if they love micro services go from go to node? Just seems dumb.

Write the micro services in Go lol.

But yeah I agree to some point. We medicate far too fast and easily these days. Half these drugs have insane side effects, and yet people shit on shrooms. At least I won’t die from blood clots or some random shit.

Re:FDA Approves First Oral Treatment for Postpartum Depression by ekianjo on Tuesday August 08, 2023 @11:16PM (#37058318)
> Anything we can do to treat it, even partially, is worth doing.

And this is exactly with this line of thinking that you get everyone including kids on antidepressant

i wonder how other countries cope without all that shit.

Re:FDA Approves First Oral Treatment for Postpartum Depression by tptacek on Tuesday August 08, 2023 @11:42PM (#37058459)
They cope by accepting higher rates of perinatal suicide.
Re:FDA Approves First Oral Treatment for Postpartum Depression by moomoo11 on Tuesday August 08, 2023 @11:33PM (#37058412)
BUt tHe sCIenCe bRo
Re:FDA Approves First Oral Treatment for Postpartum Depression by duncan-donuts on Wednesday August 09, 2023 @12:22AM (#37058655)
My wife couldn’t sleep after giving birth to our second kid and it spiraled quickly into full blown psychosis. My wife still can’t sleep right nearly 10 years later.

There’s no shame in taking antidepressants. Some of us have brains that don’t work quite right and we should have more options than “cope” or self terminate.

Re:FDA Approves First Oral Treatment for Postpartum Depression by j45 on Tuesday August 08, 2023 @11:55PM (#37058531)
Thank you. Well said.
Re:FDA Approves First Oral Treatment for Postpartum Depression by topato on Wednesday August 09, 2023 @12:51AM (#37058828)
I don't think he was trying to downplay the severity of postpartum symptoms.... In reality, it does take months for oral psychiatric drugs to cause a state of homeostasis in a patient, so perhaps, while it's another option in an arsenal, there are more serious healthcare industry related issues that need fixing as well
Re:FDA Approves First Oral Treatment for Postpartum Depression by hapticmonkey on Tuesday August 08, 2023 @09:14PM (#37057610)
I mean, it's not like the FDA are the ones who control legislation around what kind of support new parents can get. Take it up with the people to vote, repeatedly, to strike down paid parental leave, medical care, and other support systems.
Re:FDA Approves First Oral Treatment for Postpartum Depression by MarkMarine on Tuesday August 08, 2023 @09:26PM (#37057686)
I’m in this right now, my wife has symptoms that are in a word, scary. The rug pull of hormones that happens after birth, they can turn a stable, well adjusted, incredibly good mom into someone who is afraid to hold their own baby.

We’re in 3 groups, we have a private therapist for this, and if it’s anything like last time there will be another light switch at 4-6 weeks where she is suddenly back to normal. This pill is another layer of support, and a necessary one so new moms with PPD can bond with their baby, and so their partner doesn’t have to manage a two year old full time during the day and a feeding every other hour at night.

I think your care and concern is well founded, it sounds like your heart is in the right place, but I think you should re-think this take.

Re:FDA Approves First Oral Treatment for Postpartum Depression by xivzgrev on Tuesday August 08, 2023 @10:41PM (#37058120)
Absolutely. My wife also has it and talk therapy was not enough. She’s now on anti depressants so I’m thrilled theres a new drug specifically for post partum.
Re:FDA Approves First Oral Treatment for Postpartum Depression by arriu on Tuesday August 08, 2023 @09:37PM (#37057748)
As a Canadian, I can confirm 12 months is not enough let alone 6 weeks… I am deeply saddened at the thought of mothers having to go back after so little time
Re:FDA Approves First Oral Treatment for Postpartum Depression by j45 on Wednesday August 09, 2023 @12:03AM (#37058563)
18 months doesn’t seem like much either
Re:FDA Approves First Oral Treatment for Postpartum Depression by refurb on Wednesday August 09, 2023 @12:26AM (#37058691)
Government should pay me 100% of wages for 18 years!
Re:FDA Approves First Oral Treatment for Postpartum Depression by flangola7 on Wednesday August 09, 2023 @04:05AM (#37059874)
Why do you think that was an acceptable comment to make? Read the room.
Re:FDA Approves First Oral Treatment for Postpartum Depression by refurb on Wednesday August 09, 2023 @06:00AM (#37060556)
Isn’t that the ideal? Not letting work interfere with raising your kid?
Re:FDA Approves First Oral Treatment for Postpartum Depression by refurb on Tuesday August 08, 2023 @09:48PM (#37057811)
Postpartum depression is not a societal illness, it's a medical problem.

This comment is no different than telling a depressed person "you have no reason to be depressed, so cheer up". Plenty of women with strong support networks get postpartum depression.

Re:FDA Approves First Oral Treatment for Postpartum Depression by fakedang on Tuesday August 08, 2023 @09:54PM (#37057857)
Why is this even the top comment? Sounds like a soundbite from someone with a severe lack of understanding of how PPD works.
Re:FDA Approves First Oral Treatment for Postpartum Depression by darklycan51 on Tuesday August 08, 2023 @10:06PM (#37057931)
Wouldn't surprise me if the person who typed this supports banning abortion, reads exactly the same.
Re:FDA Approves First Oral Treatment for Postpartum Depression by pfisherman on Tuesday August 08, 2023 @11:00PM (#37058226)
Is is that crazy to think that a wild swing in steroid hormone levels can lead to depression - similar to what we observe when men come off of steroid cycles? If so, is something like post cycle therapy for women recovering from pregnancy really that crazy of an idea?

I don’t know enough to speak intelligently about the underlying biology, but an interesting theory I heard from someone more knowledgeable than me is that the sudden drop in progesterone - which tamps down neuroinflammation - sends the microglia (immune cells of the brain) into overdrive which results in rapid destruction of neural tissue which is experienced by the patient as profound feelings of unhappiness / depression. This is not unlike the runaway inflammatory response that kills people with COVID — which is why dexamethosone (an immunosuppressant) reduces mortality.

Re:FDA Approves First Oral Treatment for Postpartum Depression by whateverman23 on Wednesday August 09, 2023 @12:17AM (#37058628)
> Is this really a pharmaceutical issue or a societal structure and support issue.

Any if it is? We surely can't solve every, or even most societal issue that causes it.

You can continue to support improvements to the societal issues of the world while still supporting pharmaceutical interventions for those who need it right now.

Re:FDA Approves First Oral Treatment for Postpartum Depression by pertymcpert on Wednesday August 09, 2023 @12:24AM (#37058671)
My wife suffered from PPD, you can take your opinion here and shove it where the sun don't shine. In the midst of her anguish, no amount of having family support could help her. I wish this would have been available.

Typical HN upvoted bullshit from people who are trying to be contrarian to every fucking good thing that's done.

Re:FDA Approves First Oral Treatment for Postpartum Depression by ildon on Wednesday August 09, 2023 @12:36AM (#37058750)
> Postpartum Depression holistic patient view versus commercial pharmaceutical treatment.The shear emotional, physical and life changes involved in having a baby is in many ways similar to PTSD. In just a few weeks your body has been physically exhausted, your mentally and emotionally drained and now you are physical/spiritually/ and emotionally bond to a new human life who is 100 percent dependent on you for its survival and well being.Now imagine this leads to a period of depression in the patient. Is this really a pharmaceutical issue or a societal structure and support issue. Perhaps even more than just that.It is depressing to me to see things like this get pushed out … just take this pill and it will help move you up a few points on our 17 point scale and cope.Instead of wow, let’s really look at what’s happening with the birthing process on how we prepare mothers and support them emotionally, physically and maybe even spiritually.Nope just take this drug and in 6 weeks you will be back to work and we can get that new kid in daycare :/#rantover
Re:FDA Approves First Oral Treatment for Postpartum Depression by ildon on Wednesday August 09, 2023 @12:38AM (#37058764)
> now you are physical/spiritually/ and emotionally bond to a new human life who is 100 percent dependent on you for its survival and well being.

Not to mention that this is the best case scenario. Unfortunately deliveries of non-alive babies carry the same postpartum problems, without the joy of life

Re:FDA Approves First Oral Treatment for Postpartum Depression by waynesonfire on Wednesday August 09, 2023 @12:46AM (#37058798)
absolutely true. i am not at all surprised we're suffering from low birth rates. we should have done what japan is doing very long ago. the amount of support new parents receive in modern society is a joke

https://www.japantimes.co.jp/news/2023/03/31/national/child-...