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Re:FDA advisers recommend approval of over-the-counter naloxone by floxy on Wednesday February 15, 2023 @07:06PM (#34812920)
I don't think most people are ODing from prescription abuse. It is fentanyl. I'd be interested to know how many are being poisoned by fentanyl-laced drugs, vs. fentanyl addicts who OD. Maybe that stat would be too hard to come by?
Re:FDA advisers recommend approval of over-the-counter naloxone by the_mar on Wednesday February 15, 2023 @07:11PM (#34812981)
But for a lot prescription meds is the gateway drug to cheaper stuff
Re:FDA advisers recommend approval of over-the-counter naloxone by ch4s3 on Wednesday February 15, 2023 @07:29PM (#34813173)
Yes and no. Very few people get started with a legitimate prescription. The typical opioid OD happens to someone who had other substance abuse and mental health problems and at some point started taking resold/stolen prescription opioids. Until fentanyl flooded the market most ODs were multi-substance and often(some 85%+ in places where coroners checked if memory serves) involved a LOT of alcohol. Now, its often just fentanyl, which is hard to dose correctly especially if you've recently tried to quit.
Re:FDA advisers recommend approval of over-the-counter naloxone by narrator on Wednesday February 15, 2023 @07:38PM (#34813265)
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Re:FDA advisers recommend approval of over-the-counter naloxone by whimsicalism on Wednesday February 15, 2023 @08:03PM (#34813496)
Most people who die from fentanyl ODs are opioid addicted. They are not getting it in other drugs - that happens (I test all my drugs for fentanyl) but is not any where near a majority of fentanyl deaths.
Re:FDA advisers recommend approval of over-the-counter naloxone by JumpCrisscross on Wednesday February 15, 2023 @09:16PM (#34814105)
> test all my drugs for fentanyl

How?

Re:FDA advisers recommend approval of over-the-counter naloxone by fragmede on Wednesday February 15, 2023 @09:40PM (#34814293)
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Re:FDA advisers recommend approval of over-the-counter naloxone by ch4s3 on Wednesday February 15, 2023 @09:43PM (#34814304)
You can buy eat kits online.
Re:FDA advisers recommend approval of over-the-counter naloxone by the_mar on Friday February 17, 2023 @04:00PM (#34840495)
do you have source for that?
Re:FDA advisers recommend approval of over-the-counter naloxone by baremetal on Wednesday February 15, 2023 @07:14PM (#34813009)
Tangentially related but it has been my experience (I knew several people who died from opioid overdose) and also in literature[1] that overdoses frequently occur after rehab. Due to a drop in tolerance.

"The clustering of the deaths from overdose in the group of patients who had successfully completed treatment is counterintuitive and illogical—unless it derives from loss of tolerance and consequent unpredictability of resumed heroin use."

[1]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC153851/

Re:FDA advisers recommend approval of over-the-counter naloxone by hammock on Wednesday February 15, 2023 @08:18PM (#34813629)
Can confirm from my own firsthand observation. Sober people relapse, often after years of being clean, and misjudge how strong the stuff has gotten. Instant OD
Re:FDA advisers recommend approval of over-the-counter naloxone by theRealMe on Wednesday February 15, 2023 @09:27PM (#34814200)
That study is from 2003. Fentanyl is a much more recent phenomenon.
Re:FDA advisers recommend approval of over-the-counter naloxone by WHYLEE1991 on Thursday February 16, 2023 @08:22AM (#34818279)
opiates definitely arent though.
Re:FDA advisers recommend approval of over-the-counter naloxone by ransom1538 on Wednesday February 15, 2023 @07:10PM (#34812964)
Yes. Its a deadly combo. Tons of cheap opioids flowing in from Mexico made with Chinese chemicals. There is no way to stop it. Flood the EU with tons of cheap fentanyl for a fair comparison.
Re:FDA advisers recommend approval of over-the-counter naloxone by mysterydip on Wednesday February 15, 2023 @07:22PM (#34813091)
> There is no way to stop it.

Isn't this what "the wall" and securing the borders was supposed to be for?

Re:FDA advisers recommend approval of over-the-counter naloxone by ch4s3 on Wednesday February 15, 2023 @07:31PM (#34813189)
Fentanyl makes a mockery of something like border control. You can fit an absurd number of doeses into a package the size of a standard letter envelope. The demand for Fentanyl is directly related to the vice grip of the DEA on prescription opioids.
Re:FDA advisers recommend approval of over-the-counter naloxone by thinkmassive on Wednesday February 15, 2023 @08:36PM (#34813795)
Case in point: ~21 million doses worth found in a backpack of a guy trying to cross the border into Arizona

https://twitter.com/BillFOXLA/status/1625936055047426048

> So far in FY23, we have seized over 476 lbs. of Fentanyl between the ports of entry along our southwest border. That's enough to kill 100 million people.

Re:FDA advisers recommend approval of over-the-counter naloxone by lazide on Wednesday February 15, 2023 @07:30PM (#34813180)
The wall was pure political theatre. Near as I can tell, it didn’t even slow down people on foot, and drugs are coming in via freight anyway.
Re:FDA advisers recommend approval of over-the-counter naloxone by phpisthebest on Wednesday February 15, 2023 @08:04PM (#34813504)
I agree that it would not stop the drug trade... but the wall was never built so calling it "political theatre" is incorrect as well, as it was completely opposed by congress, and faced all kinds of lawsuits that stopped building several times.

"The Wall" as envisioned by the proponents was never completed

Re:FDA advisers recommend approval of over-the-counter naloxone by lazide on Wednesday February 15, 2023 @08:56PM (#34813944)
Plenty of parts of a wall for photo ops were completed!

The whole thing doesn’t need to exist for political theater, in fact I’d say its lack of actual completion makes it even more a theatrical construction than if it actually was done!

Re:FDA advisers recommend approval of over-the-counter naloxone by kevviiinn on Wednesday February 15, 2023 @07:25PM (#34813127)
Yea but that doesn't work because that's not where its coming through
Re:FDA advisers recommend approval of over-the-counter naloxone by John23832 on Wednesday February 15, 2023 @07:49PM (#34813364)
And it’s everywhere. It’s used as the “razzle dazzle” to add a kick to highs. Fake pills, heroine.

There’s even been a rash of fentanyl overdoses in nyc from marijuana (as reported by the victims). It’s thought that mass produced weed is being grown with plant growth regulators. These make the plant grow big, dense buds. It also makes the plant produce less thc. It’s believe that the plants are then being dusted with fentanyl to replace the lost thc.

Re:FDA advisers recommend approval of over-the-counter naloxone by zoklet-enjoyer on Wednesday February 15, 2023 @08:36PM (#34813805)
Buuulllllshiiiiiiit. If anything, people would be adding things like jwh18 or newer stuff like delta 8 or 10
Re:FDA advisers recommend approval of over-the-counter naloxone by John23832 on Wednesday February 15, 2023 @09:08PM (#34814034)
Big Fent is more potent/cheaper than those.
Re:FDA advisers recommend approval of over-the-counter naloxone by zoklet-enjoyer on Wednesday February 15, 2023 @09:43PM (#34814308)
I know. It has been for a decade. But it doesn't make sense
Re:FDA advisers recommend approval of over-the-counter naloxone by r3trohack3r on Wednesday February 15, 2023 @07:57PM (#34813429)
Any references to the marijuana fentanyl problem? I’ve heard versions of this story repeated every few years since the mid 2010s but have never been able to find actual evidence for it.
Re:FDA advisers recommend approval of over-the-counter naloxone by John23832 on Wednesday February 15, 2023 @09:05PM (#34814016)
Frankly, it’s what I’ve heard my delivery weed service carriers. I live in nyc.
Re:FDA advisers recommend approval of over-the-counter naloxone by whimsicalism on Wednesday February 15, 2023 @08:02PM (#34813483)
> It’s believe that the plants are then being dusted with fentanyl to replace the lost thc.

Bah, apocryphal.

Re:FDA advisers recommend approval of over-the-counter naloxone by MavisBacon on Thursday February 16, 2023 @09:56AM (#34819436)
my background is in harm reduction and as far as I know there is no credence to these tales. There are people in the U.S. overblowing the fentanyl situation either to stoke fear or sometimes it's just well-meaning undereducated folks

fentanyl has generally speaking only made it's way into the supply of non-opioids like cocaine as the result of contamination, not intentional adulteration. When we talk about fentanyl, in reality what's out there is perhaps some true fentanyl but a lot of fentanyl analogues that are much more potent (lethal dose in the mcg range). Often the people moving heroin are also moving cocaine and other drugs, and using shared surfaces to weigh and cut the product for street use. They aren't properly cleaning surfaces and instruments and thus fentanyl is ending up in all sorts of powdered drugs

fentanyl on weed has probably happened in some instances of intentional poisoning of an individual but I'd file this under similar in risk to your child being given an edible, or candy with a razor blade on halloween