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Re:LSD-like molecules counter depession without the trip by bowsamic on Sunday October 02, 2022 @02:10AM (#33053334)
[deleted]
Re:LSD-like molecules counter depession without the trip by isoprophlex on Sunday October 02, 2022 @02:33AM (#33053465)
The experience is highly variable between people. I'm sorry you had such a rough time, and I'm hoping that things are at least slowly getting better for you.

About the god thing, my 2 cents. "god" doesn't always mean Christian White Old Guy on a Cloud Looking Angrily Downwards. There's a less narrow interpretation.

If psychedelics strip away your day-to-day preoccupations, and show you life with a vastly different set of mental filters in place, many people experience a transcendent feeling of belonging to something bigger than their sober selves. A connectedness to other humans and nature that goes beyond ordinary experience. The idea that death isn't so bad, only suffering is; and suffering is the price we must pay for the ability to see its opposite, beauty.

Which people then conversationally condense to "yeah you meet god"

Re:LSD-like molecules counter depession without the trip by bowsamic on Sunday October 02, 2022 @02:37AM (#33053494)
So they just mean a transcendent, spiritual experience?
Re:LSD-like molecules counter depession without the trip by isoprophlex on Sunday October 02, 2022 @02:39AM (#33053506)
Yeah i guess that's a lot more accurate if you want to avoid the cultural baggage of the god-word
Re:LSD-like molecules counter depession without the trip by swayvil on Sunday October 02, 2022 @08:50AM (#33055487)
It expands your consciousness is a popular way of describing it.

Imagine a chronic obsessive cellphone gazer. One day he lifts his nose from the screen. Sun! Clouds! Birds and squirrels!

Except moreso.

Re:LSD-like molecules counter depession without the trip by bowsamic on Sunday October 02, 2022 @04:04PM (#33059655)
But shouldn’t God be in all things, including the profound, if he’s really the Absolute? I doubt he’d be limited to our human conception of nature
Re:LSD-like molecules counter depession without the trip by swayvil on Sunday October 02, 2022 @04:59PM (#33060201)
I prefer to observe first, theorize second.
Re:LSD-like molecules counter depession without the trip by bowsamic on Sunday October 02, 2022 @05:08PM (#33060291)
So He is more of a Kami?
Re:LSD-like molecules counter depession without the trip by swayvil on Sunday October 02, 2022 @05:19PM (#33060398)
That would be one of those theories.
Re:LSD-like molecules counter depession without the trip by canadiantim on Sunday October 02, 2022 @10:01AM (#33055920)
This is a really good explanation
Re:LSD-like molecules counter depession without the trip by avisser on Monday October 03, 2022 @10:02AM (#33067640)
For me, on one of my trips, I had a profound feeling of being part of life in the universe. Like this feeling of how vast the universe is, but it's all dead rocks, except for everything on this tiny blue world (and hopefully more). I felt like a part of that.

So no deities but spiritual like what you said.

Re:LSD-like molecules counter depession without the trip by PraetorianGourd on Sunday October 02, 2022 @02:27AM (#33053435)
I am confident the OP meant “meet God” as short-hand for “a spiritual and transcendental experience wherein the ego is destroyed and rebuilt anew with a profoundly different perspective”.

I don’t think anyone would earnestly claim that there is zero risk to any hallucinogenic experience. One of my hopes is that through study we can better understand the ingredients that lead to profoundly positive experiences vs. profoundly traumatizing experiences. And anyone who claims we know that today is acting in bad faith.

Re:LSD-like molecules counter depession without the trip by ipnon on Sunday October 02, 2022 @02:57AM (#33053598)
Roland Griffiths’ foundational psilocybin study did not have any adverse outcomes. They used a simple protocol: no patient or patient family history of schizophrenia or bipolar, patients underwent cognitive behavioral therapy before and after the trial, patients were made to develop a warm and trusting rapport with the physicians before administration, and a physician was on hand for the duration of the psilocybin administration to coach the patient through unforeseen disturbances and administer anxiolytics in the case of panic attacks. With this simple protocol they reported no adverse affects, although they also did not report a 100% rate of efficacy. Griffiths wrote an entire separate study on this protocol, it is self-recommending.
Re:LSD-like molecules counter depession without the trip by PraetorianGourd on Monday October 03, 2022 @01:07AM (#33063658)
This one? https://pubmed.ncbi.nlm.nih.gov/27909165/

Terminal cancer patients, those expecting to die and “meet God” soon, are a very, very niche audience compared to a general population with non-specific major depressive disorders.

But at the same time, I love this. The more study, the better!

Re:LSD-like molecules counter depession without the trip by ipnon on Monday October 03, 2022 @02:08AM (#33063983)
After seeing the responses to my original post I wish I had used different terms. I did not mean "meeting God" literally, but used it more as a metaphor for "meeting your maker": coming to terms with universal human problems like mortality, our relations to our friends and family, the nature of good and evil, things of that nature. "Meeting God" I thought would sum all this up poetically, but you can always count on HN to take things literally!

Griffiths' research is all high quality. He is the pioneer in making this field of scientific research palatable to the mainstream medical establishment.

Re:LSD-like molecules counter depession without the trip by Schroedingersat on Sunday October 02, 2022 @03:07AM (#33053649)
Meeting is just a way of describing a numinous experience. I have heard atheists, christians, pagans and sikhs alike use the term. Mathematicians often use it to describe especially profound proofs regardless of religion.
Re:LSD-like molecules counter depession without the trip by ruined on Sunday October 02, 2022 @02:28AM (#33053442)
if i were unhappy with my life after an epiphany, i would simply act to change my situation
Re:LSD-like molecules counter depession without the trip by naasking on Sunday October 02, 2022 @10:27AM (#33056128)
> if i were unhappy with my life after an epiphany, i would simply act to change my situation

It's anything but simple if you're depressed. You seem to think that insight drives motivation, but in depressed people these are often decoupled. You can have all the insights you want but the motivation to do anything just does not manifest.

Re:LSD-like molecules counter depession without the trip by ruined on Monday October 03, 2022 @04:47PM (#33073464)
my post is formatted after a meme, in which the joke is the speaker is ignorant of the difficulty inherent in the suggested course of action.

it's a little tongue-in-cheek. of course changing your life is hard. but, if you are dissatisfied with your life, it is also the only solution.

Re:LSD-like molecules counter depession without the trip by bowsamic on Sunday October 02, 2022 @02:36AM (#33053487)
The only great impulse of change I had after my trips was an intense urge to kill myself
Re:LSD-like molecules counter depession without the trip by andai on Sunday October 02, 2022 @03:03AM (#33053625)
Curiously, antidepressants can trigger suicide in suicidal people because they give them the energy to act on those impulses.

My friend was suicidal, and psilocybin was the only thing that made him go back to wanting to be alive (though the effect only lasted ~2 weeks each time).

Re:LSD-like molecules counter depession without the trip by parineum on Sunday October 02, 2022 @01:59PM (#33058486)
>Curiously, antidepressants can trigger suicide in suicidal people because they give them the energy to act on those impulses.

As someone with somewhat first hand experience with this, it's not exactly "gives them the energy".

The anti-depresents I started taking worked exactly as advertised. The "problem" was I wasn't just depressed, I was also just not happy with life. Anti-depresents can get you out of a depression but they won't make you happy.

It was a bit enlightening to understand the difference between the sadness I felt and the depression but it can also make you feel more helpless when the depression lifts and you still don't really want to wake up tomorrow.

As a result of this experience, I think it's irresponsible to prescribe anti-depresents without accompanying therapy.

Re:LSD-like molecules counter depession without the trip by ruined on Sunday October 02, 2022 @02:42AM (#33053522)
what, with no reason? you didn't have a why? fix the why.
Re:LSD-like molecules counter depession without the trip by bowsamic on Sunday October 02, 2022 @02:47AM (#33053552)
It didn’t show me a why it just showed me that I want to die. Other LSD users say I should take more at a higher dosage but that seems like a bad idea
Re:LSD-like molecules counter depession without the trip by chaps on Sunday October 02, 2022 @03:22AM (#33053735)
What dosage did you take? I've heard low doses can actually be a deeply frustrating experience.
Re:LSD-like molecules counter depession without the trip by bowsamic on Sunday October 02, 2022 @03:40AM (#33053816)
100ug
Re:LSD-like molecules counter depession without the trip by ruined on Sunday October 02, 2022 @10:15AM (#33056034)
you keep looking at LSD for feelings you're having while sober. examine your reasons for your feelings now. if you can't identify your own motivations, how can you attribute cause like that?
Re:LSD-like molecules counter depession without the trip by bowsamic on Sunday October 02, 2022 @01:29PM (#33058136)
I wasn’t ever suicidal before, I was after, that’s all I know
Re:LSD-like molecules counter depession without the trip by mistermann on Sunday October 02, 2022 @02:36PM (#33058838)
A theory / thought experiment:

Take "it just showed me that I want to die" and unpack every single word into an absurdly and "pedantically" complex, comprehensively and perfectly correct articulation of the(?) precise meaning in this context. In doing so, use various forms of articulation, not only paragraph/narrative form.

If you are doing it right, ideally you will find yourself having to fight against your own mind at several points during the analysis.

Work on the problem for a month or six, even just two or three minutes at a time now and then. I propose that at the end of this process, you will possess more knowledge than you did before.

There are various techniques to accelerate this process, but I will let you figure those out on your own along the way. As a hint: consider various topics of discussion that arise on the website you are on.

I should probably also note: this is not necessarily a risk-free undertaking, so maybe build some safeguards into your methodology.

Re:LSD-like molecules counter depession without the trip by bowsamic on Sunday October 02, 2022 @04:02PM (#33059639)
I have literally no idea what the hell you are talking about
Re:LSD-like molecules counter depession without the trip by mistermann on Monday October 03, 2022 @09:24AM (#33067177)
Too much to ingest at once, fair enough!

"unpack the meaning of a word"...this makes sense?

Re:LSD-like molecules counter depession without the trip by bowsamic on Monday October 03, 2022 @10:58AM (#33068390)
Not really no
Re:LSD-like molecules counter depession without the trip by mistermann on Monday October 03, 2022 @04:13PM (#33073017)
Can we agree that words have meanings?
Re:LSD-like molecules counter depession without the trip by ruined on Monday October 03, 2022 @04:58PM (#33073607)
if you are unable to identify motivations and reasons for your own actions and desires, there is certainly a more complex causal relationship here, and you probably need some assistance to discover it.
Re:LSD-like molecules counter depession without the trip by bowsamic on Wednesday October 05, 2022 @02:48AM (#33092108)
I am on a waiting list for therapy, as I said. I'm not sure what else you want from me. I have no idea why I want to die
Re:LSD-like molecules counter depession without the trip by ceejayoz on Sunday October 02, 2022 @10:52AM (#33056350)
Not all whys are known, and not all known whys are fixable.