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Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by nklmilojevic on Monday August 23, 2021 @10:57AM (#28276760)
I'm really amazed that there are a lot of antivaxx people here on HN.

Sad to see smart people talking about "consent" when public health is in danger.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by hn_throwaway_99 on Monday August 23, 2021 @11:06AM (#28276914)
> Sad to see smart people talking about "consent" when public health is in danger.

It's really not difficult at all to see how "public health" taking precedence over anything can very easily lead to government overreach that is unwarranted.

I get frustrated with antivaxxers not necessarily because they are against mandates, but because their arguments for not getting vaccinated are complete and utter nonsense.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by s1artibartfast on Monday August 23, 2021 @11:30AM (#28277369)
It is unfortunate that there is no middle ground between the two. Discussion has devolved into ideological camps and all nuance has been lost.

I am vaccinated, advocate others getting vaccinated, have immunocompromised family, but am uncomfortable with mandated medical treatments.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by ufmace on Monday August 23, 2021 @11:58AM (#28277858)
You're right. There are also edge cases that seem to get lost in the mania of one side or the other.

What if you've already had Covid and recovered? The data seems a lot less certain about whether the vaccine is a clear advantage over the natural antibodies that you have from a natural recovery.

What if you genuinely have allergies or other issues that might cause serious complications with receiving a vaccine? People like this definitely do exist.

Those issues are both real. Alas, it's also tough to prove for certain that somebody is in one of those buckets and not making something up because they're afraid of the vaccine.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by mrstumpy on Monday August 23, 2021 @11:02AM (#28276840)
It's grossly unfair to say that someone who doesn't want a Covid vaccine is antivaxx. There are a plenty of legitimate reasons one might not get the covid vaccine.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by Retric on Monday August 23, 2021 @11:06AM (#28276912)
Being anti vaccine seems like the definition of an antivaxx. What’s the difference in your mind?

The antivaxx community is filled with people willing to take some vaccines but not others.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by mrstumpy on Monday August 23, 2021 @11:12AM (#28277026)
There is a difference between being anti-vaccine, meaning that you are against all vaccines, and being hesitant to receive a specific vaccine. Most people I know who are still waiting to receive the covid vaccine are all caught up on the typical vaccines and may even get the flu shot every year.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by Retric on Monday August 23, 2021 @11:14AM (#28277056)
Most people in the antivaxx community are willing to take some vaccines. Being 100% anti vaccination was never the core issue.

Random article on the subject: You can essentially break anti-vaxxers into two groups, says Tim Caulfield, the Canada Research Chair in health law and policy at the University of Alberta. The first consists of full-on disbelievers who make up somewhere between two and five per cent of the population, depending on which study you look at. Their minds won’t be changed. The second group — somewhere between 20 and 30 per cent of Canadians — is for what some now call the vaccine-hesitant. They may get some of the required vaccinations for their children, but not all of them. https://nationalpost.com/news/canada/who-are-the-anti-vaxxer...

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by JumpCrisscross on Monday August 23, 2021 @11:14AM (#28277060)
> a difference between being anti-vaccine, meaning that you are against all vaccines, and being hesitant to receive a specific vaccine

Philosophically, yes. Practically, no. If you are voluntarily unvaccinated because you’re a nutter or are lazy, you’re the same risk to the public.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by josephcsible on Monday August 23, 2021 @11:13AM (#28277036)
Being in favor of vaccines in general, but not the ones for COVID.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by nolok on Monday August 23, 2021 @11:18AM (#28277139)
This is even worse in my mind.

"Oh I'm totally for vaccine, but not the one that went through full trials and helps stopping the actual pandemic going on right now, nope, that one is a no go better people keep dying when we could stop it"

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by dolni on Monday August 23, 2021 @11:30AM (#28277366)
It didn't go through full preclinical trials. What are you on about?
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by Retric on Monday August 23, 2021 @11:33AM (#28277414)
The normal sequence of tests aren’t about human safety for the general public their about human safety of the test subjects in the clinical trials including primates. So they did pre clinical trials like this one, but they did fast track to primate testing. https://www.biorxiv.org/content/10.1101/2020.09.08.280818v1

At this point we have more data on COVID vaccinations than most prescription medications as their so widespread.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by gthtjtkt on Monday August 23, 2021 @11:25AM (#28277273)
That's like saying "if you dislike any single black person for any reason you're racist".
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by Retric on Monday August 23, 2021 @11:47AM (#28277649)
You only need to accept one vaccine for each disease, not every vaccine for each disease.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by martin_a on Monday August 23, 2021 @11:05AM (#28276895)
> There are a plenty of legitimate reasons

Which? Next to medical reasons there are none.

It's just selfishness and not caring about the greater good and health of society, your neighbours, colleagues, friends or family.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by unyttigfjelltol on Monday August 23, 2021 @11:24AM (#28277255)
Heart inflammation. Weighing of peronal risk factors, e.g., age or lack of comorbitities. Weighing social factors, e.g., prevalence of breakthrough infections and concomittant low value to 'health of society' from inconvenience of one or two injections that are required to achieve official vaccination.

I'm not prejudging how an individual's assessment of risks and benefits might shake out and I personally feel it's not a huge deal either way. That said, I very greatly disagree with the sense of entitlement baked into the comment I'm responding to, e.g., that I and all others should collectively drop everything and abandon all personal preferences and goals to focus single-mindedly on defeating the virus. The flaws with the majoritiarian premise are at least three-fold. 1. We most certainly will not defeat the virus in any way-- history teaches that we will at best coexist with it. 2. The viral risks are not infinite and easily may be overshadowed in many cases by life circumstances-- I am not required to quit my life and livelihood to serve majority sensibilites or lack thereof. 3. Before this pandemic I had some sense that my choices are personal, sometimes private, and always mine-- the pandemic has made me realize those sentiments are not universal, but have not persuaded me I'm wrong.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by DangitBobby on Monday August 23, 2021 @12:02PM (#28277929)
> that I and all others should collectively drop everything and abandon all personal preferences and goals to focus single-mindedly on defeating the virus

This is SO dramatic! It's just a vaccine! It's done in less than an hour! Wearing a mask is not fucking hard! What happened to American tenacity and strength in the face of adversity? How do these things even make your life harder?

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by martin_a on Monday August 23, 2021 @11:31AM (#28277389)
> Heart inflammation.

The risk of getting this due to an acute Covid infection is eight times higher than after getting the vaccination.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by kaiju0 on Monday August 23, 2021 @11:43AM (#28277568)
We beat small pox, polio and other terrible diseases with the all in approach. Please take the shot and convince everyone you know to do so as well. If we eradicate this... it's gone.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by silicon2401 on Monday August 23, 2021 @11:15AM (#28277077)
> not caring about the greater good

This is an emotional appeal that has been used to justify countless atrocities in countless civilizations. A rational society shouldn't be thinking in such blanket and qualitative ways

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by tpush on Monday August 23, 2021 @11:30AM (#28277364)
Actions are bad because of their nature, not because of how they are reasoned for. And any given reason can be used to justify bad or good actions; that doesn't taint the reasoning.

That is to say, judging an action solely by its reason is intellectually lazy; Especially because you can just interrogate the action and its effects themselves.

To make it clear: Saying getting vaccinated is dangerous because the 'greater good' is also used to justify atrocities seems like something profound, but it actually lacks any insight whatsoever.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by tpm on Monday August 23, 2021 @11:25AM (#28277261)
In this case though the greater good is very easily expressed in a quantitative way: more vaccinated people means less people dead and incapacitated by the virus.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by DangerousPie on Monday August 23, 2021 @11:24AM (#28277252)
It's not an emotional appeal though. It's pretty clear that a high vaccination rate will be beneficial to the overall health and prosperity of a population. I don't care about people getting vaccinated because it makes me feel warm and fuzzy, I care about them getting vaccinated so that we can ramp down restrictions and get closer to normality.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by silicon2401 on Monday August 23, 2021 @11:26AM (#28277286)
> a high vaccination rate will be beneficial to the overall health and prosperity of a population.

Then say that, don't say "the greater good". The "greater good" means very different things to Nazis or Islamist terrorists. We should encourage people to say what they mean, not vague and meaningless phrases like "greater good".

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by randomopining on Monday August 23, 2021 @11:27AM (#28277300)
What kind of silly response is this? Of course a rational society would look at the impact of individual decisions extrapolated over the collective.

If nobody got the covid vaccine, would things be better or worse across our society than they are now? Simple question, simple answer, but something you are ignoring and thus you aren't rational.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by s1artibartfast on Monday August 23, 2021 @12:12PM (#28278098)
Of course a rational society would look at this, but it should not only look at this.

Unbounded utilitarian arguments can be used to justify any number of atrocities, and therefore must be bounded by human rights and other factors.

Ultimately, it comes down to what you are and aren't measuring when you are assessing "impact over the collective".

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by randomopining on Tuesday August 24, 2021 @07:01PM (#28296045)
Of course. Using an open-ended "well it could lead to this" disregards any nuance that my argument has.

Anything complicated like this requires nuance.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by cloudwalking on Monday August 23, 2021 @11:23AM (#28277218)
There is no blanket logic here. This is not an atrocity. This is an instance of global pandemic, literally a 100-year natural disaster affecting all of humanity. It's not some slippery slope about your "freedom", stop trying to make it into one.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by valenterry on Monday August 23, 2021 @11:57AM (#28277851)
> This is an emotional appeal

Spock wants to have a word with you.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by disambiguation on Monday August 23, 2021 @04:49PM (#28281732)
go give away all your money and possessions right now

anything less is just selfishness and not caring about the greater good and health of society, your neighbours, colleagues, friends or family.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by thehappypm on Monday August 23, 2021 @11:12AM (#28277029)
If you have natural immunity, getting a vaccine seems rather pointless.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by YPPH on Monday August 23, 2021 @11:18AM (#28277143)
>If you have natural immunity, getting a vaccine seems rather pointless

Not according to a recent Oxford study. Quite the contrary, actually.

https://www.ndm.ox.ac.uk/covid-19/covid-19-infection-survey/...

>Two doses of either vaccine still provided at least the same level of protection as having had COVID-19 before through natural infection; people who had been vaccinated after already being infected with COVID-19 had even more protection than vaccinated individuals who had not had COVID-19 before. [my emphasis added]

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by thehappypm on Monday August 23, 2021 @11:21PM (#28284759)
Is your quote compelling
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by mbesto on Monday August 23, 2021 @11:21AM (#28277193)
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by gthtjtkt on Monday August 23, 2021 @11:23AM (#28277227)
> Which? Next to medical reasons there are none.

COVID vaccines aren't eligible for the VICP and have a laundry list of horrific side-effects, that's plenty of reason for any reasonable person.

> It's just selfishness and not caring about the greater good and health of society, your neighbours, colleagues, friends or family.

You can say the same about fat people, smokers, drinkers, and all other people who take unnecessary risks of any kind. They're all burdens on the healthcare system that reduce access and affordability for everyone else.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by bradly on Monday August 23, 2021 @11:29AM (#28277355)
> You can say the same about fat people, smokers, drinkers, and all other people who take unnecessary risks of any kind. They're all burdens on the healthcare system that reduce access and affordability for everyone else.

They cannot kill someone by walking by them in a grocery store.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by jrmg on Monday August 23, 2021 @11:40AM (#28277533)
> laundry list of horrific side-effects

This kind of hyperbole really damages the debate.

A “laundry list of horrific side-effects” sounds like there are known long-term problems that result from getting the vaccine.

This is simply not the case. There is a list of side effects, but it’s not long, and no reasonable person should consider them to be ‘horrific’.

https://www.cdc.gov/coronavirus/2019-ncov/vaccines/expect/af...

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by Qw3r7 on Monday August 23, 2021 @11:04AM (#28276893)
Such as ?
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by mrstumpy on Monday August 23, 2021 @11:08AM (#28276956)
1. ~30 million confirmed (worldometer) recovered from covid. Some official estimates put that number closer to 100 million. Those individuals already have covid immunity and do not need to take a vaccine. All vaccines carry some risk, even if low. There is no reason for someone who already has covid immunity to take on the risk of a vaccine.

2. Guillain-Barre syndrome

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by iamben on Monday August 23, 2021 @11:38AM (#28277504)
Friend had Covid last year, wasn't too bad. Caught it again in Jan (before the chance to get vaccinated) and it hit her very hard. She's now suffering from a pretty miserable long Covid.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by Buttons840 on Monday August 23, 2021 @11:17AM (#28277121)
Covid has a low chance of risks. The Covid vaccine has a low chance of risks. People are bad at judging probabilities at the fringes.

Yes, the chance of risks from Covid is orders of magnitude higher than the vaccine. People are still bad at it.

Politics didn't help the situation.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by baron_harkonnen on Monday August 23, 2021 @11:46AM (#28277631)
I'm fully vaccinated, but don't think it's crazy for people to be suspicious of the vaccine.

In recent years huge swath's of the united states have been suffering from another epidemic: the opioid crisis. It is well established that a major part of this epidemic was caused by many of the same major pharmaceutical companies that are now claiming to have developed a vaccine in record time.

What's sad is that this legitimate concern has been whipped up by one side into a completely irrational frenzy that no longer makes coherent sense. I don't trust big pharma companies as a general rule, but I also don't believe that micro chips are being implanted (or even could be) into a vaccine. So, imho, legitimate vaccine skepticism is transformed into insane conspiracy thinking.

What is also sad though is that the reaction against vaccine skepticism has been equally turned into an insane "what are you anti-science!?!" Pharmaceutical companies are complicit in the death of hundreds of thousands of individual over the last decade. Being skeptical of the claims of these companies is common sense, not anti-science. We're also seeing consist contradictions about safety and efficacy of the vaccine. There are already complex side effects and the break through rate among full vaccinated is much higher than initial claims.

For me personally the vaccine still makes sense, and it certainly seems like our best path forward as far as policy efforts to end the pandemic. However the current language and public discourse on the topic is ridiculous.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by johnnyb9 on Monday August 23, 2021 @11:23AM (#28277225)
Actually, a recent study showed there is a "U" shaped curve where the least educated and the most highly educated are the most vaccine hesitant. https://www.medrxiv.org/content/10.1101/2021.07.20.21260795v...
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by c618b9b695c4 on Monday August 23, 2021 @12:35PM (#28278432)
Granted, I am in my own little bubble, but at $WORK (pharmaceutical company where 90%+ people have a phd), there is nothing but enthusiasm for getting vaccinated. I wish there was a breakdown between disciplines - STEM vs humanities.

As an aside, according to random internet site, 1.7% of Americans have a phd.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by kif on Monday August 23, 2021 @11:06AM (#28276918)
For me it's not about being anti-vax. My wife had horrible abdominal pain after getting her Pfizer shot, and she still suffers from fatigue almost two weeks after. We had COVID and for her it was much easier than the vaccine.

When it comes to "consent", it's the same as the whole Apple CSAM ordeal. Why talk about consent when it's for the good of children?

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by tpush on Monday August 23, 2021 @11:14AM (#28277061)
HN has a decent amount of nut jobs (of all kinds) on it. I don't think it correlates much with intelligence.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by system16 on Monday August 23, 2021 @11:11AM (#28277002)
I often wonder if the coronavirus were not a respiratory disease and had more visible effects like polio, would we still see such a significant antivaxx movement.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by mikece on Monday August 23, 2021 @11:34AM (#28277419)
Being opposed to mRNA gene therapy is NOT the same as being anti-vax. Likewise, being opposed to any vaccine which is developed using stem cells or tissue from aborted babies due to deeply held moral convictions doesn't make one anti-vax. A true anti-vaxxer is opposed to vaccine EVERYWHERE AND ALWAYS. There are very, very few people in that fringe category.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by oezi on Monday August 23, 2021 @11:49AM (#28277692)
But mRNA technology is not a gene therapy.

As an analogy:

mRNA technology is NOT like sending a saboteur into a factory to change the blue prints / designs / masters records (=genes) of the factory.

Rather it is like dropping a bunch work instructions (RNA snippets) over the factory and have some workers (cells) pick them up and build the things described there-in.

mRNA tech isn't the same as CRISPR.

The worst that could happen is that a work instruction that we inject becomes self-replicating (a virus), but because it can't replicate to begin with it there is no way that it mutates to gain such an ability.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by dangoor on Monday August 23, 2021 @11:43AM (#28277571)
[mRNA vaccines are distinct from gene therapy](https://www.reuters.com/article/factcheck-covid-mrna-gene/fa...).
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by badwolf on Monday August 23, 2021 @12:55PM (#28278735)
I'm neither amazed, nor surprised at the utterly insane amount of antivaxxers here in any way.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by veeti on Monday August 23, 2021 @11:18AM (#28277135)
Sad to see smart people talking about "privacy" when children are in danger.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by flyingfences on Monday August 23, 2021 @11:27AM (#28277323)
Is this sarcastic, or...?
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by josephcsible on Monday August 23, 2021 @11:29AM (#28277343)
Arguments like that one are why iOS scans all of your photos now.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by mtnpuma on Monday August 23, 2021 @01:52PM (#28279512)
I agree. Saddened about this, considering the usual level of discussions in here.
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by a_imho on Monday August 23, 2021 @11:49AM (#28277691)
A lot compared to what?
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by gjsman-1000 on Monday August 23, 2021 @11:34AM (#28277421)
What happened to My Body My Choice?
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by forgingahead on Monday August 23, 2021 @11:13AM (#28277044)
There is a large continent of space, ideas, and legitimate reasons between "trust everything government/big pharma seems to have panicked agreement on" and "the government is trying to microchip me".

It's important to have that clear-headed discussion, not this elite arrogance that discussion and arguing the points is somehow bad for discourse or society.

People are rightfully skeptical of new pharmaceuticals based on new technology with zero long-term studies being not just approved and being sold, but also being required for basic activities in society like earning a living.

There is definitely an argument to be made about not being locked down forever, and finding a way forward despite endemic COVID. But vaccine passports, and accusations that anyone with a hint of hesitation is "anti-vaxx", is a terrible way to engage and broaden the tent so all concerns are heard and addressed.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by nemothekid on Monday August 23, 2021 @11:24AM (#28277254)
> There is a large continent of space, ideas, and legitimate reasons between "trust everything government/big pharma seems to have panicked agreement on" and "the government is trying to microchip me".

This is lip service to make it seem like vaccine hesitant individuals have a legitimate argument when they actually don’t. It’s impossible to have a clear-headed discussion when the other side’s argument pretty much comes down to gut feel at best and government conspiracy at worst. If you are (oddly) skeptical of MRNA technology, then the J&J vaccine exists and is also free.

There are well over 100MM shots administered since April and the worst side effect as been a dozen blood clots in women who had a pre-existing condition that caused them. Anyone who tells you they aren’t safe is trying to sell you a bridge. If you want to argue against hard data, then you must have an actual data-backed argument or we can just assume you aren’t a serious person.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by dolni on Monday August 23, 2021 @11:33AM (#28277413)
> There are well over 100MM shots administered since April and the worst side effect as been a dozen blood clots in women who had a pre-existing condition that caused them.

Thalidomide was perfectly safe, too, until kids started being born without arms and legs. Oops.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by nemothekid on Monday August 23, 2021 @11:38AM (#28277488)
Thalidomide never got fda approval. What are you talking about? Why bring it up?
Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by dolni on Monday August 23, 2021 @11:39AM (#28277515)
Neither did any of the vaccines before people started getting them.

What are _you_ talking about?

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by nemothekid on Monday August 23, 2021 @11:58AM (#28277857)
1. Thalomide, according to Wikipedia, had fewer doses administrated than 100m

2. No regulatory body in America ever claimed it was safe to use before the side effects were discovered.

I don’t see how the comparison is apt. The FDA doesn’t have a track record being too cavalier when it comes to public health so I don’t understand why you would bring up an example of the FDA doing their job to imply they aren’t doing their job

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by dolni on Monday August 23, 2021 @12:10PM (#28278073)
> No regulatory body in America ever claimed it was safe to use before the side effects were discovered.

US regulatory bodies said that the COVID vaccines were safe before blood clotting and myocarditis were discovered.

> The FDA doesn’t have a track record being too cavalier when it comes to public health so I don’t understand why you would bring up an example of the FDA doing their job to imply they aren’t doing their job

You're a little too hung up on "The FDA". "The FDA" isn't a person. "The FDA" of 50 years ago isn't "The FDA" of today.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by nemothekid on Monday August 23, 2021 @12:37PM (#28278466)
> US regulatory bodies said that the COVID vaccines were safe before blood clotting and myocarditis were discovered

The CDC paused the rollout of J&J after fewer than 50 cases to do further research and understand what factors cause blood clots. Once understood they resumed the vaccine rollout.

By that same logic - Tylenol/acetaminophen is also known to cause liver problems in a small number of otherwise healthy individuals. Is your logic here that Tylenol should also be declared unsafe?

> "The FDA" of 50 years ago isn't "The FDA" of today.

By that very same logic then what does the distribution of Thalomide 50 years ago have to do with the FDA of today then?

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by forgingahead on Monday August 23, 2021 @11:27AM (#28277304)
You don't seem like you've had much (if any) discussion with folks who are concerned about the vaccine.

I would suggest not taking what you see on TV and the internet as gospel and engage with a few folks in real life.

There are certainly people who you won't be able to have a discussion with, but you're not being that open-minded either by shutting down everything by declaring "they don't have a legitimate argument".

*Edit: The myocarditis issue is real. Please don't handwave away legitimate concerns because of lack of understanding and compassion.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by nemothekid on Monday August 23, 2021 @11:31AM (#28277377)
> There are certainly people who you won't be able to have a discussion with, but you're not being that open-minded either by shutting down everything by declaring "they don't have a legitimate argument".

Again you are playing lip service. If there are legitimate arguments you would list them. Either you don’t know them and you are carrying water for charlatans or they don’t exist. This kind of argument would not be tolerated in any other field of science. Can you imagine Einstein saying “The speed of light is constant for all observers but you need to talk to these people, who I won’t tell you who they are, to figure out why?”

I’ve had these discussions before and it almost always turns out the “blessed” arguments are just wordier statements of constantly debunked talking points

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by s1artibartfast on Monday August 23, 2021 @12:35PM (#28278437)
On the medical side, the legitimate arguments I see is:

1) Concern over long term effects which we have no data on (legitimate but low probability in my estimation)

2) Natural immunity is slightly less effective than the vaccine against alpha variants, but still very robust. These people should therefore be exempt from the vaccine.

---

On the policy side, the legitimate arguments/discussions I see are:

3) We should strive for a society where consent is obtained by changing minds, not force, even if this is extremely difficult.

4) Slippery slope concern- There is no hard limit or consensus on when public health outweighs bodily autonomy and other considerations.

5) Who owns the responsibility to ensure personal safety. (should the obligation fall on people who don't want to catch covid to avoid public spaces and take defensive action, or fall on people who could be spreaders in the public spaces)

---

If it helps to have a productive discussion, I declare my tribe as vaccinated and encouraging others to get the vaccine.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by nemothekid on Monday August 23, 2021 @01:07PM (#28278907)
1) Is the only fair argument in which vaccine pushers would have egg on their faces. You need to balance this argument against (1) the predicted lives saved by the vaccine and (2) the documented long term effects of the vaccine. This argument cannot be considered in the vacuum. Let's say X number of people die due to long term effects of the vaccine. We know historically this number is low, but we cannot be certain. However we do know the cost of inaction last year cost nearly 500,000 excess deaths. Should we allow another 500,000 to die in order to do further testing of an otherwise safe vaccine? How many people, in your opinion, should suffer today until there is enough testing for you?

2) This is a public policy problem. Let's say you allow this; then everyone, in lieu of getting an actual vaccine will just claim they had COVID already.

3) No one is getting forced to take the vaccine. Vaccine mandates just mean you can be prevented from entering certain federal buildings until you are vaccinated. This is not a new power - children have been mandated to get vaccines to enter public schooling. If you don't want to get a vaccine, then society has kindly asked you to not step on a plane.

4.) This is only a slippery slope to people born after the time where vaccines have pretty much eradicated most contagious diseases. Previous vaccine mandates for polio and chickpox did not lead the USG into forcibly inoculating children with super soldier serum. It's a slippery slope to you because you weren't around that last time this power was enforced.

5.) Following this logic - should the government be banned for giving you a ticket for not wearing a seatbelt? Should the government allow the sale of cars without airbags? After all if I drive safe why should I pay extra for seatbelts and airbags? The short answer is - we do these things because, you living in a society, can cause negative externalities. If you drive a car without seatbelts and airbags you cause not only danger to your passengers, but also to the emergency services system that has to pry you from your car. You are only "free" from your responsibility as long as you pledge to not visit a hospital and operate on yourself. Otherwise it's simply unfair that someone who could have gotten vaccinated should occupy an ICU bed from someone who cancer. The second you are in the ICU, your "responsible" decision now must fall on nurses, doctors and other patients.

Again, I want to stress, I do not think these are very strong or well-researched arguments against the vaccines at all. I hope I have answered your arguments non-combatively, but I want to point out I do not think these are strong or even well intentioned arguments now that we are more than a year into this pandemic. Only one of your arguments had to do with actual safety and public policy, and the rest I believe came down to your personal opinion of how things should be done. I'm sure you are a smart individual, and again I don't mean this in combative manner but I'm going to trust the people who have been studying this for years. Going back to my original comment, most arguments against the vaccine are "gut-feel" at best and not backed by any actual data.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by s1artibartfast on Monday August 23, 2021 @03:02PM (#28280451)
1) I fully agree that there is a tradeoff between predicted deaths and risk from vaccine. I am fine with any number of people dying because they self selected to not take the vaccine, be it 500k or 5 million. I respect their right to choose even if I don't agree with it. The debate thickens when you talk about future deaths of people who selected to get a vaccine, but died from breakthrough cases. Vaccination breakthrough cases are very rare at <0.1% of total cases[1], and vaccination still confers significant benefit against severe cases or death. For sake of argument, I would accept an annual deaths of 50K (similar to the flu) among the vaccinated before further government action is considered. I think this range is achievable given we had 500k deaths before the vaccine was widely available. We now have 160 million Americans self selected to vaccinate and this number is still climbing, The CDC also estimates that 100+ million Ammericans have already been infected.

2) I split the topics into scientific 1 & 2 vs political 3-5, and think this is more a question of science. If natural immunity is reasonably close to vaccination immunity, I think they should be treated the same (whatever that may be). This is the question that science can answer. For your implementation concern, positive covid test or antibody test would be a simple way to administer an equivalent immunity pass.

Questions 3-5 are political because they can not be answered by science or data. Science can inform the decision, but they come down to questions of values, morality, ect.

3) I agree nobody is being tied down and given a shot, and only wackos are advocating this. There is a scale for how hard society can incentivize or punish people until they get a vaccine. I personally think society has done a terrible job of informing people to change their mind, and skipped straight to the punishments, and am deeply uncomfortable with this.

4) I agree that past vaccinations were largely a success via eradication. I have not seen a success criteria stated for the covid pandemic, as eradication is unlikely. At what point will we stop ratcheting up control mechanisms? X deaths per year, sustainable hospital capacity of Y? Is any sacrifice warranted to prevent 1 death?

5) Again, this is political question, and reasonable can and do have different opinions on how much personal risk you can take on, and when the government should protect you from yourself. You brought up seatbelts, going on somewhat of a tangent, the things you described are not true negative externalities in the technical sense. They are cost society chooses to pay, and could simply choose not to. I could give a beggar $5 but that isn't an externality. If I make a rule that I will give every beggar I see $5, it still isn't an externality. If the beggar on the corner lowers my property value, that IS a negative externality because it is imposed on me and I have no control or choice. You can say that seatbelts and vaccines both reduce the cost to the social safety net. Lots of things would reduce costs, and we can choose to to pay them, or not, opposed to controlling people. I personally love seatbelts, but think that tickets for adults are unreasonable (different story for minors in their care, ect).

>I don't mean this in combative manner but I'm going to trust the people who have been studying this for years. Going back to my original comment, most arguments against the vaccine are "gut-feel" at best and not backed by any actual data.

With the exception of the first two, these arguments aren't backed by data because they aren't questions that can be answered by data. They are simply matters of opinion, and I think we would all be best served if we acknowledge this. At the end of the day, science can conclude that universal vaccination would reduce deaths, or save $X, but it cant answer question on what public policy should be. This will be different based a multitude of values in addition to deaths and money.

Opinions you disagree with (assuming they are not based on incorrect data) are not wrong, just different.

https://www.kff.org/policy-watch/covid-19-vaccine-breakthrou...

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by nemothekid on Monday August 23, 2021 @04:07PM (#28281252)
1.) The vaccines are less effective if not everyone gets vaccines, and are much less effective if the vaccine is allowed to mutate. For that reason I _don't_ respect decisions to not get vaccinated. It's _not_ a personal decision and I consider this point wrong because I fully reject this framing. By not getting vaccinated you put others at risk. If you go to the hospital for COVID you put other people fighting other diseases at risk. I might agree with you had vaccinated people had 0 risk of getting COVID (or even getting into another accident and needing an ICU bed), but that isn't the case so you cannot assume that someone rejecting vaccine has zero negative externalties.

2.) I'll have to do more research, but I can only assume that natural immunity is not reasonably close to vaccination immunity which is why it's not an appropriate replacement. I saw a Fox News segment last night that said essentially natural immunity is a perfect solution, but I don't accept things from Fox at face value.

3.) States are literally paying people money to get vaccinated - no one "skipped straight to punishments". The vaccine is completely free with very few barriers, in a country with no socialized medicine. This kind of framing feels deliberately misleading. I don't know what more you expect the state to do at this point - even Trump is telling people to get vaccinated to boo-ing crowds.

4.) The success criteria has been ICU bed capacity. That is the key criteria that seperates the regular old flu from COVID. That is why efficacy rate stress hospitalization rates, and not breakthrough rates. When you have mass ICU usage, that is when a pandemic becomes a public policy problem.

5.) I don't feel your response has addressed my point. I brought up seat belts because it's something the government does today to enforce personal responsibility. You framed forced mandates as some government overreach on personal responsibility and I'm saying that isn't the case and the government has always had that power. Secondly if you refuse to get the vaccine and end up in the hospital - why aren't you framing this decision as someone selfishly controlling doctors, nursers and other patients to deal with their selfish decision? The doctor has "no control or choice" in being forced to treat you to a respirator. When the public health officials tell you get a vaccine that's being "imposed on you and I have no control or choice", but when you catch or infect someone else with COVID, it's 100% ok in imposing your choice on nurses? I hope I've highlighted the hypocritical selfishness of your argument.

>They are simply matters of opinion, and I think we would all be best served if we acknowledge this.

Again, they are not. They are poorly researched opinions and that is why I continue to reject them. You said the state "skipped straight to punishments". That's not true. You said "there's no success criteria". That's not true, it has always been ICU capacity. These two "opinions" are demonstrably false statements that are masquerading as "harmless opinions". To me that's misinformation. Your fifth point just exposes your selfishness. I'll give you that you have your own personal freedom to be selfish, but I wouldn't be shocked if you are called an asshole for acting selfishly.

Re:FDA grants full approval to Pfizer-BioNTech’s Covid shot by s1artibartfast on Monday August 23, 2021 @06:16PM (#28282705)
1) I fully acknowledged that vaccination choice can have impact on others. I stated that a 50k death toll would be acceptable. Do you have a death toll that you would accept the choice of other people to not get vaccinated?

2) I'm OK to defer this until the science is in.

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3) Vaccination rates are climbing, and we have no idea where they will end. In many demographics they are already quite high. Uptake is 91% in 65+ and 73% for 18+. Breakthrough cases are extremely low at <0.1% of cases, so 99.9% of cases are self imposed by choice of not to get vaccinated. One easy thing that states could do is wait, let the numbers continue to climb, let people change their mind as all their vaccinated neighbors walk around fine, or their unvaccinated neighbors die, or they get sick and get a decent level of personal immunity. As of today, the death rate is 0.3/100k per day. That is 359,160 deaths per year, of which 360 will be people who chose to get vaccinated but died of a breakthrough case. This is pretty close to the CDC numbers, which puts the the breakthrough deaths for the first 4 months of 2021 at 160 people, who had a mean age of 82 [1]. For context, lawn mower accidents kill >1000 people a year in the US.

4) I still don't think that an objective goal has been communicated. Less covid cases, or more ICU capacity is not an objective or achievable goal. What is the criteria for ICU beds, what is the metric, and what is it now? Is it a national average, or until every hospital in the country meets it, ect? The CDC has stopped tracking ICU capacity as of July 2021 with an average of 60% of beds full and doesn't even report the number of those which are covid related. All bed occupid with covid patients was 8-9% (including the asymptomatic admitted for other reasons), but I admit this could be higher in the ICU. If this is the primary goal for our pandemic response, we should at least track where we are relative to the goal. If there is a measurable goal you can share, I would be ecstatic, and it might change my opinion that we are in a foreverwar against covid with no success criteria (not unlike Afghanistan & the war on terror).

My guess is that we will continue aimlessly focus time and resources into it without any idea of what completion looks like until everyone is burnt out and comes to the realization that covid is endemic. We will check vaccination cards when traveling, for employment, and potentially events out of fear of triggering one of the 360 breakthrough deaths. My mental model for the war on Covid is largely based on the war on terror, and I think there are several parallels.

5) I would rather live in a world where doctors, hospitals, and insurers were free to refuse services to the unvaccinated, than one where people were both compelled to get medical treatment, and provide health services.

>[these] are poorly researched opinions and that is why I continue to reject them. You said the state "skipped straight to punishments". That's not true. You said "there's no success criteria". That's not true, it has always been ICU capacity. These two "opinions" are demonstrably false statements that are masquerading as "harmless opinions". To me that's misinformation. Your fifth point just exposes your selfishness. I'll give you that you have your own personal freedom to be selfish, but I wouldn't be shocked if you are called an asshole for acting selfishly.

"Skipped straight to punishments" was vague and exaggerated language. Replace that with implemented punishments faster than I would like. Is that sufficiently an opinion now? I stand my by statement that there is no success criteria. I never said opinions are harmless. For example, I said that it would be tolerable to have 50k vaccinated covid deaths. That is a real opinion, that if enacted, would let people die.

As mentioned before, I am fully vaccinated, and will probably get a booster when available. I just have a very high tolerance for other people being assholes or selfish. More so when we have what looks to be a very effective vaccine available for "free" and boosters on the way to provide a huge degree of protection to those who want them.

[1] https://www.cdc.gov/mmwr/volumes/70/wr/mm7021e3.htm