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Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by avar on Thursday April 12, 2018 @04:17AM (#16818925)
The latest episode of Econtalk "Vincent Rajkumar on the High Price of Cancer Drugs" is relevant to this subject: http://www.econtalk.org/archives/2018/04/vincent_rajkuma.htm...

It discusses structural issues relating to why drugs are so expensive (mainly in the US). Some of it's regulatory (e.g. Medicare not being allowed to negotiate drug prices), or there being no ceiling on prices related to efficacy as in many other countries.

But some of it's because nobody in the system seems to have a real incentive to reduce costs, even when the benefits are worth it. E.g. an example that's mentioned is that doctors will usually describe the latest brand medicine that's outrageously expensive, instead of a generic that's cheap and statistically almost exactly the same thing when it comes to efficacy.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by jseliger on Thursday April 12, 2018 @07:59AM (#16819930)
But some of it's because nobody in the system seems to have a real incentive to reduce costs, even when the benefits are worth it

This is a really underrated point and part of the reason I'd like to start by seeing price transparency: http://seliger.com/2018/03/27/preventive-care-doesnt-save-mo... . Bizarrely (or at least, bizarrely to me) this doesn't seem to be part of the political discussion at all.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by maherbeg on Thursday April 12, 2018 @09:36AM (#16820742)
I am very strongly with you here. Why can’t we get an exact cost upfront before Abby services are rendered? A doctor can make orders and should be able to get the exact cost to you before submitting them.

These prices should all be public and comparable. Common reasons to go to the doctor should be shown alongside their costs.

We got a surprise $19k bill that we were told would be $160 and our insurance would cover the rest. We’re letting them fight it out but would be very disappointed if we had to pay that out of pocket. We would never have ordered the test then, or would have tried to shop around

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by pg_bot on Thursday April 12, 2018 @12:59PM (#16822808)
This is how we run our medical clinic in South Carolina. All of our prices are public and we try to get you the lowest possible cost. You will never receive a bill for which you did not know the price ahead of time. We support this by having a $49/month membership fee and by not accepting insurance. (Most additional charges are under $20)
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by chimeracoder on Thursday April 12, 2018 @01:35PM (#16823133)
> We support this by having a $49/month membership fee and by not accepting insurance.

This is the trick. Accepting insurance - in particular, Medicare and Medicaid, because of their particular reimbursement model - makes it impossible for most providers to provide up-front pricing.

Typically the providers who can are for specialized treatments that don't intersect with other specialists much, like outpatient psychiatry or psychotherapy (you'll see this a lot in places like New York, where the demand is high enough that good psychiatrists can ensure a steady stream of patients even if they don't accept any insurance, and they rarely need to refer people to other specialists). I'm glad you're able to operate a practice like this elsewhere, especially for a non-psychiatric (I'm assuming) medical clinic.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by npongratz on Thursday April 12, 2018 @01:48PM (#16823227)
> Accepting insurance - in particular, Medicare and Medicaid, because of their particular reimbursement model - makes it impossible for most providers to provide up-front pricing.

I must be missing something. Suppose I tell the provider I am going to pay them cash, directly; I will not use Medicare, Medicaid, or any other insurance. Are you saying that because said provider accepts Medicare/Medicaid for other patients, it is impossible for them to tell me ahead of time what they are going to charge me?

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by robotrout on Thursday April 12, 2018 @02:20PM (#16823530)
Yes. I believe the problem is that they negotiate the prices with the insurance companies. They have to start high, so they can negotiate down. They actually do have a price list, that you can sometimes bully them into giving you, which are the prices that they submit to begin negotiations with the insurance companies. But, as you can imagine, those prices on that list are crazy high, as they are intended to be negotiated down, not actually paid.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by jaggederest on Thursday April 12, 2018 @03:28PM (#16824129)
Insurance contracts also often include "most favored nation" provisions or equivalent, where any discount you give other people must also be given to the insurance company.

This is also why commercial/retail space will generally negotiate on almost anything but the rent per square foot, since if they lower that, all the other tenants will immediately demand lower rent.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by dclowd9901 on Friday April 13, 2018 @03:20PM (#16833119)
So, if I understand you correctly, every time someone visits a health care provider under insurance, they have to perform the billing like they're buying a house or car?

No fucking wonder health care costs a goddamn fortune.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by _jal on Saturday April 14, 2018 @10:05AM (#16837356)
No, that's wrong. It is far worse than that.

There's an entire industry of entities involved with medical pricing. One of the players in one of the larger niches, a Pharmacy Benefits Manager[1], recently bought an insurer[2]. Manipulating, negotiating and offering various financial and marketing products (it gets really blurry) around medical pricing is huge business.

[1] https://en.wikipedia.org/wiki/Pharmacy_benefit_management

[2] https://www.nytimes.com/2017/12/03/business/dealbook/cvs-is-...

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by chimeracoder on Thursday April 12, 2018 @03:16PM (#16824033)
> I must be missing something. Suppose I tell the provider I am going to pay them cash, directly; I will not use Medicare, Medicaid, or any other insurance. Are you saying that because said provider accepts Medicare/Medicaid for other patients, it is impossible for them to tell me ahead of time what they are going to charge me?

Yes. Medicare and Medicaid generally reimburse rates that are below COGS, so providers have to make up the difference with what they charge private insurers. If they didn't, they would literally go out of business - if you have to pay $100/unit wholesale to purchase a vaccine and Medicare only pays you $93 for the entire visit during which you administer the vaccine, you won't be around very long unless you can get private insurers to pay much more, to cover not only the $7 unit loss, but also enough to pay for all the overhead of running a practice (wages, office space, etc.)[0].

They'll make up the difference by requesting much more from private insurers, though they don't know a priori how much they'll get. In the end, private insurers typically peg their rates to multiples of what Medicare reimburses (for example: "we'll agree to pay 350% of Medicare's reimbursable rate for all reimbursable billing codes").

For various reasons (including both logistical and legal ones), they can't present one bill to private insurers and a different bill to self-paying patients. The amount that they'll accept to settle the bill may be dramatically less than the amount they bill for[1], but they can't provide different bills up-front.

So, any provider that accepts insurance is basically incapable of providing you in advance with a price quote that represents what you'll actually pay, regardless of whether or not you are actually on insurance.

In theory, providers who only accept a very small set of insurances and accept no Medicare patients would be able to do this. But in this day and age, you're almost never going to find one of those providers - the overhead of accepting insurance is large enough that it's to their advantage either to accept several different forms, or to refuse insurance altogether. And once you're taking insurance, you basically can't refuse Medicare patients (logistically and legally: some Medicare patients receive dual coverage or receive their Medicare coverage wholly under private plans, and you can't turn a patient away just because you discover that they're on Medicare if you're otherwise capable of accepting their insurance).

[0] These numbers are illustrative; Medicare (in aggregate) reimburses 7% less than costs.

[1] If you're insured, every time you visit the doctor, you probably receive an explanation of benefits statement, which shows that they were billed $1000, but their maximum reimbursable rate is $300, and they'll cover $250, so you're required to pay $50. The difference between $1000 and $300 is what I'm referring to here.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by pbhjpbhj on Thursday April 12, 2018 @07:19PM (#16825822)
>Medicare (in aggregate) reimburses 7% less than costs //

So, do I have this right, Medicare is state funded - they pay the doctor less than the cost of manufacturing the medicine and the doctor over-charges other people's insurance companies so as to pay for fixed costs and add profit, to the drug company and themselves?

Your expansion under [1] makes no sense - you were billed $1000, the insurance paid $300 and charged you $50 of that; who is paying the $700? Are you just saying that those at the point of delivery barter by trying to charge $1000, hoping you'll pay it, but the insurance company negotiates a 70% discount? Rather than having an actual cost for a treatment.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by realbarack on Thursday April 12, 2018 @11:31PM (#16826950)
Re: your last paragraph: yes, that is how it works. That $1000 rate is known as the "chargemaster" rate and it's absurdly, incredibly inflated. A hospital maintains a chargemaster list, which is how they bill uninsured patients. Insurers negotiate rates which are a fraction of this chargemaster rate. The chargemaster rates are also not public, I believe.

So, unintuitively, uninsured people (at least the ones who can pay their bills) are great for care provider revenue.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by npongratz on Friday April 13, 2018 @10:47AM (#16830451)
Here's where I am further confused, then. If the provider has this list of chargemaster rates (inflated though they may be), and I tell them I'm paying cash, no insurance of any kind involved, shouldn't they be able to tell me at that moment what they will charge me?
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by pg_bot on Thursday April 12, 2018 @09:22PM (#16826403)
"So, do I have this right, Medicare is state funded - they pay the doctor less than the cost of manufacturing the medicine and the doctor over-charges other people's insurance companies so as to pay for fixed costs and add profit, to the drug company and themselves?"

For certain things, yes that is the way it works. I believe most medical practices are losing money when they administer a vaccine.[0]

[0]: http://pediatrics.aappublications.org/content/124/Supplement...

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by makmanalp on Thursday April 12, 2018 @10:00AM (#16820961)
Because hospitals use those prices to negotiate with insurance and other parties. I'm not saying it's right, but it's what happens in a broken system:

https://en.wikipedia.org/wiki/Chargemaster

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by tathougies on Friday April 13, 2018 @12:34PM (#16831567)
My wife and I visited the Mayo Clinic this year, and I was surprised and relieved that they had a giant PDF file of every service they offer (which is a lot) and the associated price. I don't understand why all hospitals don't have this. The price we ended up paying, since it wasn't covered by insurance, is basically exactly what it said on the pricing sheet.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by conanbatt on Thursday April 12, 2018 @10:57AM (#16821570)
The doctor doesn't know what the claim is going to be. It takes sometimes weeks to know how much you charge at all.

This is because insurance companies pay in base on what you did or how long you did it. You itemize each visit like a tax return that later gets reviewed. Then someone reads the return and thinks if it makes any sense.

After that, they pay back the doctor, but according to the plan, they also have to charge the patient the copay.

That said, a doctors office that is only cash will get very little patients. Because people that are employed will not go to a cash-only doctor's office.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by pg_bot on Thursday April 12, 2018 @01:03PM (#16822848)
Not true. I own and run a cash only doctor's office. Coming to us is cheaper than most insurance co-pays.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by japhyr on Thursday April 12, 2018 @01:26PM (#16823063)
Your posts are pretty interesting. If you don't mind a couple questions:

- What range of services do you offer? Do you take care of broken bones? Long-term illnesses? What kinds of things do you refer people to a full hospital for?

- Are there many offices like yours around? How unusual is your office?

- How easily could you build an entire hospital on this model? What would the limits of that be?

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by pg_bot on Thursday April 12, 2018 @03:55PM (#16824359)
We run a primary care clinic. The specific type of clinic we run is called "direct primary care". There are around 800 clinics like ours in the United States but the service is generally catered to the wealthy. For more details about the scope of practice you can read the following link.[0] When we cannot provide a service in house we usually help someone navigate the medical system. There is a lot of information asymmetry when dealing with healthcare and we help even that out for our clients. We also partner with other companies to get reduced prices on imaging, labs, and other services.

I don't believe you can run an entire hospital on this model. Hospitals/insurance are best suited for unpredictable events. Our model is great for chronic and predictable events.

[0]: https://en.wikipedia.org/wiki/Primary_care_physician#Scope_o...

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by pillfill on Thursday April 12, 2018 @03:30PM (#16824142)
Not OP, but I'm familiar with a couple primary care providers that don't file insurance claims. It's refreshing to see up-front pricing on their website for services they offer, e.g.: https://www.palmettoproactive.com/services-pricing
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by conanbatt on Thursday April 12, 2018 @06:37PM (#16825590)
I agree! Its great, but lots of people have insurance already so they want to use that to get their primary care, so that 200 dollar visit becomes 40 bucks.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by conanbatt on Thursday April 12, 2018 @06:34PM (#16825568)
Are you primary care? Because I cant see a primary care competing on price vs insurance that charges 20 dollars/30% on copay.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by pg_bot on Thursday April 12, 2018 @09:11PM (#16826347)
It depends on what your deductible is. With the increasing cost of healthcare, we are seeing companies go with higher and higher deductible plans. We don't compete solely on price, however our prices are extremely competitive even for people who have insurance. (we are often cheaper than medicare/medicaid) We also work with businesses as part of their benefit plans. The major benefit of this system is time, we can schedule longer appointments with a more flexible schedule than most other doctor's offices.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by kbart on Thursday April 12, 2018 @03:29PM (#16824134)
Wow, so do I understand right, that in USA you don't know the cost of medicine before buying them? What's the reasoning behind that?
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by hackeraccount on Thursday April 12, 2018 @06:16PM (#16825423)
Third parties payers is the reason. As a general matter if you have insurance - private, medicare, medicaid - and the reason isn't anything crazy / chronic then the price is never out of the world. Chronic conditions add up but the people in those cases generally know what the cost is ahead of time. And if you don't have insurance either you're able to pay out of pocket or you just don't pay and then get care anyway.

Which is to say it's all madness.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by refurb on Thursday April 12, 2018 @04:28PM (#16824648)
For a script you fill at a pharmacy? Sure, you can find out exactly what it will cost before buying.

Medical treatment by a physician or hospital? No, you can't really find out.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by tomohawk on Saturday April 14, 2018 @07:22AM (#16836873)
These guys

https://surgerycenterok.com/

are able to provide up front pricing. But if they were to accept medicare, they wouldn't be able to.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by kafquaesque on Friday April 13, 2018 @05:24AM (#16828284)
Price transparency makes a lot of sense in general. With Hospital EHR purchases IIRC there was a ten time difference in price between similarly sized organizations as an extreme.

Here is a version of price transparency as a bill: https://revcycleintelligence.com/news/house-reps-introduce-h...

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by solotronics on Friday April 13, 2018 @03:22PM (#16833156)
there should be a law in the US about price transparency for healthcare

You should be able to see a common list of treatments and work done for general practitioners and specialists and it should be searchable on the internet.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by RodericDay on Thursday April 12, 2018 @09:01AM (#16820426)
Price transparency is the crucial reason why markets can claim to propagate information quickly and lead to efficiency.

The opacity in the labor market and the drug market is not an accident.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by bluGill on Thursday April 12, 2018 @10:42AM (#16821406)
In fact who care most about cost actually have a perverse incentive to increase costs!

Health insurance is tied to your job, and your company pays most of the costs for you. If you choose to get your own insurance you don't get to take the amount your company pays, so you cannot afford to. This ties you to your company making it harder to just leave, first you have to find a new job. The more prices go up the harder it is to leave and live off your savings for a few months.

Obama promised "if you like your insurance you can keep it". However what wasn't said is "if hate your insurance you have no choice but to keep it". I don't like my insurance, but since I otherwise like my job there is nothing I can do about it.

Until the government changes the above prices will get higher.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by NickM on Thursday April 12, 2018 @01:43PM (#16823186)
Obama promised "if you like your insurance you can keep it". However what wasn't said is "if hate your insurance you have no choice but to keep it". I don't like my insurance, but since I otherwise like my job there is nothing I can do about it.

To be fair, this was a worse problem prior to Obamacare. At least now we have the exchanges, and companies can't deny you coverage for preexisting conditions. I agree with what you're saying, and the current system certainly has big problems, I just don't think you can blame Obama for that.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by bluGill on Thursday April 12, 2018 @01:55PM (#16823282)
I blame Obama for not fixing it. You are correct about problems with the old system, but since I had insurance that didn't affect me.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by burntwater on Thursday April 12, 2018 @03:10PM (#16823975)
I think you can be disappointed Obama wasn't able to fix it. But blaming him for something that ultimately involves thousands of politicians and special interest groups is, I feel, unfair.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by jknoepfler on Thursday April 12, 2018 @03:33PM (#16824167)
a much better question would be "who in congress was responsible for our not being able to crate modern public healthcare system?"

The answer is certainly not the liberal/progressive wing of the Democratic party.

The existing policy is a compromise that liberals signed off on to improve the conditions of the worst off, but they were not able to create the kind of conceptually coherent total overhaul we would require to make the system rational.

I agree with you that blaming Obama for a failure of leadership in this situation is borderline absurd, but it's a simple narrative that is easy to regurgitate in a complex, frustrating world, so we have to forgive people for believing it, to some extent.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by tomohawk on Saturday April 14, 2018 @07:18AM (#16836862)
What's absurd is that there were many problems in healthcare 1.0 that needed fixing, and Obamacare chose to instead solidify the position of health insurance providers, which was central to the problems in 1.0. Now we have 2.0 and the insurance companies have their business model baked into the law even more strongly.

A one page bill could probably fix the whole thing

* move tax benefit of buying insurance from employer to employee (why is my company involved in my health insurance anyway?)

* allow buying of insurance across state lines

* require same price for all services, tests, medicines regardless of payer

* require those prices to be public

* declare a single 'pool' or market for insurance (just like federal employees have)

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by jknoepfler on Saturday April 14, 2018 @11:07AM (#16837615)
sure, but that wouldn't even get 40 votes in the Senate, much less 60.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by joe_fro on Friday April 13, 2018 @12:07AM (#16827069)
I was curious about who did vote for the bill so I took a look:

https://en.wikipedia.org/wiki/Patient_Protection_and_Afforda...

The bill passed in the Senate by 60-39 with all republicans voting against except for Jim Bunning who did not vote. With 58 Democrat and 2 Independent votes the Republicans weren't able to filibuster. After the bill passed the senate a special election to replace Ted Kennedy in the senate was won by a Republican, so the Democrats no longer had a super majority in the Senate, and so the decision was made that the house should pass the Senates bill as they didn't think voting on a house bill would pass the senate now that the Republicans had 41 votes which was enough to filibuster.

> The existing policy is a compromise that liberals signed off on to improve the conditions of the worst off

The only compromises happened between members of the Democrat party, between moderates and progressives.

> I agree with you that blaming Obama for a failure of leadership in this situation is borderline absurd

I agree that there are likely a lot of compromises that happened behind the scenes that we didn't see, but there has to be some ownership of that bill by President Obama. It was his marquee bill at a time when some Democrats were urging him not to tackle it, he had a super majority in the senate and the house. He signed it into law, he set the agenda, I think it's fair to hold him accountable for the outcome, even if it's not exactly what he wanted, it's still what was passed and if he didn't like it they could have scrapped it to try again.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by jknoepfler on Friday April 13, 2018 @12:52AM (#16827201)
great response and research. I agree with you that Obama shares a solid share of responsibility - but more importantly I think the enormous amount of effort required to keep a supermajority in line to pass the legislation is the real story.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by DesiLurker on Thursday April 12, 2018 @02:25PM (#16823570)
the healthcare reform was a result of complicated partisan maneuvering to get over the finish line. many of those bandaids people complain about are a direct result of strong republican opposition. so much so that the final bill that passed was nowhere near what obama or anyone wanted. Blaming Obama and not the opposition in congress for any of this mess is really shortsighted.

if you really want to know the gory details of this process and healthcare in america read the excellent book by Steve brill:America's Bitter Pill.

and one more thing, you had insurance now but what happens in you lose your job or god forbid take a break for a few month to care for somebody.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by joe_fro on Friday April 13, 2018 @12:12AM (#16827083)
The Democrats passed the bill in the senate 60-39, with 2 independents voting for, and all Republicans voting against. Then that bill was passed in the house with a vote of 219–212 with 34 Democrats and all 178 Republicans voting against it. This wasn't partisan, this was Democrats passing a bill without any Republican votes. The band-aids were to get moderate Democrats on board.

https://en.wikipedia.org/wiki/Patient_Protection_and_Afforda...

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by NickM on Tuesday April 24, 2018 @10:08AM (#16912677)
Lieberman singlehandedly killed the public option, though. Obamacare would have looked very different if that had survived.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by bluGill on Thursday April 12, 2018 @02:46PM (#16823754)
Irrelevant since he never tried to fix the problem.

He did try for the other problems, and there was a lot of opposition.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by DesiLurker on Thursday April 12, 2018 @08:34PM (#16826182)
are you trolling? if you are serious about finding out read the book, he explains the horsetrading that was needed to pass the bill.

for a complex bill like that you cannot take one thing in isolation and complain you have to look at the context. Also, again, its congress not him. if you are gonna complain, complain about republicans that kept watering down the obamacare under bad faith negotiations (though eventually it passed without any red support).

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by smt88 on Thursday April 12, 2018 @01:59PM (#16823323)
Obama couldn't fix anything because he was the president and he couldn't make laws. He barely even had the political clout to get ACA passed.

The blame is on Congress.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by darpa_escapee on Thursday April 12, 2018 @11:41AM (#16822065)
The way the current tax regime and economic system are setup in the US, they both favor the employer-employee relationship heavily and, in a way, penalize a worker for existing outside of it.

Personally, I don't think that's a coincidence.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by snuxoll on Thursday April 12, 2018 @03:04PM (#16823920)
See self-employment tax for a good example. Yes, it really is just the other 7% of the FICA (payroll) tax that an employer would normally pay, but I've seen people get thrown for a loop when another 7% of their 1099 or self-employment income gets taken away than they were "expecting" because it gets hidden from normal W-2 employees.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by icelancer on Saturday April 14, 2018 @06:29PM (#16839930)
>> Obama promised "if you like your insurance you can keep it".

And, of course, this was a massive lie. Personally, I loved my previous insurance but after ObamaCare, it went away and my replacements were far more expensive.

It was the 2013 Lie of the Year by Politifact, even.

http://www.politifact.com/truth-o-meter/article/2013/dec/12/...

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by monocasa on Thursday April 12, 2018 @01:27PM (#16823074)
And part of the ACA capped profit percentages of the insurance companies, meaning that in order to increase total profit they need to increase revenue and spending quarter after quarter.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by Aloha on Thursday April 12, 2018 @06:22AM (#16819420)
In every US state that I know of - a generic will be substituted for a brand name drug unless the doctor specifically specifies that it should not be.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by alistairSH on Thursday April 12, 2018 @10:37AM (#16821356)
There's a subtle difference between what you're describing and what the parent post describes.

You are correct - in cases where there is a brand-name version of a dug AND also a generic version of the same drug, the generic is usually provided unless the brand-name is specifically requested.

But, the parent post is describing cases where there is a new, brand-name drug that fills the same niche as an existing generic. Two different drugs, but often only slightly differing results. MDs often prescribe the newest, assuming it's better than the generic. MDs receive much of their ongoing education about drugs from the pharmaceutical sales reps, so they are bombarded with ads and samples (just as consumers are with ads on TV).

As an aside, my dermatologist has been good about ensuring the costs of any treatments I receive are managed. She's recommended specific pharmacies, brand-name vs generic, and other tips/tricks to reduce the costs. This despite the fact that I don't directly bear any of the costs because I have a decent medical plan.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by ubernostrum on Thursday April 12, 2018 @12:58PM (#16822800)
MDs often prescribe the newest

That is not always a correct assumption. Due to the way some programs like Medicare pay out, doctors are sometimes strongly incentivized to prescribe the most expensive drug.

Ophthalmologists are the usual notorious example, prescribing for macular degeneration. Medicare's reimbursement for drugs administered in-office includes paying the cost of the drug plus an additional percentage.

For macular degeneration, research showed Avastin and Lucentis are basically equally effective. But Avastin is ~$50/dose and Lucentis is ~$2,000/dose. If you're going to get a "bonus" payment equal to a percentage of the cost of the drug, which one would you use?

Lucentis has at times accounted for 10% of the entire Medicare part B drug budget because of this.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by alistairSH on Thursday April 12, 2018 @03:06PM (#16823945)
Wow! I didn't know about that quirk of the Medicare system. That's a pretty horrific incentive to overspend.

My comment was based on the more typical situation, where the physician sends the patient to a pharmacist.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by LordKano on Thursday April 12, 2018 @12:20PM (#16822425)
It sounds like your dermatologist is not just a good doctor but also a good person.

Giving the same (high?) standard of care to patients without regard to their financial resources.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by avar on Thursday April 12, 2018 @06:45AM (#16819518)
I was unclear, the podcast discusses cases where there's no generic version of the latest drug, and the latest drug is marginally more effective than whatever the latest generic is.

So the generic just doesn't get considered, even though it would be suitable for the patient at much lower costs. This is unrelated to the situation you're describing.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by Aloha on Thursday April 12, 2018 @08:51AM (#16820320)
Having a medical condition that requires long term medication maintenance - every single doctor I've had is very well aware of what is a generic and what is not - and tends to prescribe a generic, as they are often an ER version of the regular med, or a compounded version of two medications that can be taken separately.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by cko on Thursday April 12, 2018 @09:31AM (#16820700)
Former pharmacist here. I think most doctors do try to be cost conscious for the patient. But there are some who prescribe the newest and expensive brand name drug, and I can’t think of any reason why except some sort of incentive program.

Many ophthalmologists will give the most expensive post surgical drops. When I called one to have him change it, he was like “uh, there’s no substitute.” I thought to myself, “then what did you guys do before these drugs came out a couple months ago?” Example: post cataract surgery people usually get an antibiotic, a corticosteroid, and an anti inflammatory. These generic drugs have been on the market for years. But new ones come out here and there that are hella expensive, we’re talking a copay of $5.00 vs $100+ per eye drop.

Also there are prescribing guidelines called step therapy. For example for diabetes: https://emedicine.medscape.com/article/117853-treatment#d10 doctors will skip the first few steps and prescribe a brand name drug immediately that’s like step 3.

Insurance companies try to stop it by requiring authorization but... I feel like we’re fighting an uphill battle with perverse incentives.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by refurb on Thursday April 12, 2018 @10:01AM (#16820975)
In my former job, I talked to a lot of doctors about this stuff.

What I found was that a lot of doctors look at the decision from a clinical lens only. Why not prescribe the latest branded product, even if it's only marginally better than the generic? Patients deserve the best, right?

Making a cost vs. benefit trade off wasn't a universal process for many physicians.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by darpa_escapee on Thursday April 12, 2018 @11:51AM (#16822173)
I've actually run into a very similar example, I was prescribed a $400 dollar bottle of antibiotic eye drops, which my insurance fought and eventually paid for. I asked why that was chosen and if there were other options that I could pursue in the future. I was told that "these are your eyes and I'm not going to [fuck around] when it comes to your vision."

I can't really disagree with that logic.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by cko on Thursday April 12, 2018 @06:25PM (#16825502)
True, but what did doctors do before these new drugs? “Fuck around” with “inferior” products... reason I’m cynical is because many new drugs that hit the market are not novel - for example loteprednol (older drug) vs difluprednate (newer): https://www.ncbi.nlm.nih.gov/m/pubmed/28628490/

By the way, some of these newer drugs don’t have to be “superior” to be approved, they just have to be none-inferior to current therapy. https://www.raps.org/regulatory-focus™/news-articles/2016/11...

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by darpa_escapee on Thursday April 12, 2018 @06:29PM (#16825526)
From what I gathered, it was more effective than the cheaper options, not that it was chosen because it was new and shiny.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by kbart on Thursday April 12, 2018 @03:34PM (#16824176)
"a generic will be substituted for a brand name drug"

We had a similar corruption here, in Lithuania, until the law has been passed that pharmacist must offer a generic alternative. But there again, world is seen very differently in EU than USA, so I don't expect that to apply on the other side of the pond.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by cptskippy on Thursday April 12, 2018 @09:38AM (#16820755)
And drug makers are aware of this fact thus they incentivize doctors to specify the brand name drug.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by thesimon on Thursday April 12, 2018 @11:55AM (#16822200)
And this makes the pharmacy give you the brand name drug?

That's surprising. Over here (Germany) the doctor can fill in the name of the brand in the prescription, but unless he ticks a special box you'll automatically get the generic.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by pbhjpbhj on Thursday April 12, 2018 @07:29PM (#16825851)
Why would a pharmacy give you a brand name, the generic is chemically identical, the doctor can give a brand name - they've done their part. The pharmacy could then offer you the brand name, or the generic, as long as they make the generic cheaper then the pharmacy can make more money; save you money and give identical service.

Some people will still opt for the more expensive, of course, but where's the incentive for the pharmacist to fill a script for Neurofen RTM with anything other than ibuprofen? Why even is there a special box -- if the generic isn't the same drug (tested, licensed, etc.) it's not a generic. Might as well have a "are you getting a kickback for prescribing this" box?

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by stordoff on Friday April 13, 2018 @06:42AM (#16828678)
Generics aren't always chemically identical. The active ingredient might be the same, but the binders may not be. In the majority of cases, that's fine - you only really care about the active ingredient - but in certain cases, such as a sensitivity to one of those ingredients, it might not be. My sister has had to have specific brands of certain medicines prescribed due to a sensitivity to certain types of sugars. For instance, compare Neurofen:

> Each tablet contains Ibuprofen 200 mg Also contains: Sucrose, Sodium Citrate, talk, Croscarmellose Sodium, Stearis Acid, Titaniu, Dioxide, Silicon Dioxide, Acacia, Carmellose Sodium, Sodiu, Laurilsulphate, Macrogol and Blank Ink(contains Shellac, Iron Oxide Black (E172) and Propylene Glycol) or Opacode S -1 -8152 HV Black (contains Shellac, Iron Oxide Black (E172, Antifoam DC1510 and Soya Lecithin

https://www.boots.com/nurofen-200mg-tablets-16-tablets

to generic ibuprofen:

> Ibuprofen 400mg, sodium starch glycollate, croscarmellose sodium, sucrose, E171, E127 and E211

https://www.chemistdirect.co.uk/ibuprofen-400mg-tablets/prd-...

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by chimeracoder on Thursday April 12, 2018 @10:06AM (#16821030)
> And drug makers are aware of this fact thus they incentivize doctors to specify the brand name drug.

That's a bold and unfounded claim. Drug makers do not incentivize doctors to write DAW on a prescription.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by cptskippy on Thursday April 12, 2018 @10:29AM (#16821263)
> That's a bold and unfounded claim.

Forbes and the New York Times have written articles on it. The Affordable Care Act has a provision that requires Doctors to disclose payments.

Empirically, I dated a girl for about 2 years who was a sales representative for a major pharmaceutical company. When I asked about her job she said it was mostly dropping of brochures, swag, free lunches, and holding contests to promote products. Top producers (doctors) received all expense paid trips to medical conferences held in exotic locations or were invited to be paid speakers at said conferences. It was not too different from what the marketers did at the insurance broker I worked for at the time to cater Agents to write their lines.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by chimeracoder on Thursday April 12, 2018 @10:36AM (#16821346)
> Empirically, I dated a girl for about 2 years who was a sales representative for a major pharmaceutical company. When I asked about her job she said it was mostly dropping of brochures, swag, free lunches, and holding contests to promote products. Top producers (doctors) received all expense paid trips to medical conferences held in exotic locations or were invited to be paid speakers at said conferences. It was not too different from what the marketers did at the insurance broker I worked for at the time to cater Agents to write their lines.

Your anecdote is about which drugs the doctors choose to prescribe. It has nothing to do with incentivizing doctors to prevent patients from filling generic versions of drugs and forcing them to purchase the brand-name version of the same drug, which is what this thread is about.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by cptskippy on Thursday April 12, 2018 @10:47AM (#16821458)
They weren't compensating them to fill scripts for the generic. She made more frequent visits to top producers based on filled prescriptions. I asked her how she knew who to visit and she said she was emailed regional reports with prescription numbers.

I don't know how those reports are generated. Do pharmacies report that information back to pharmaceutical companies? Are they based off of shipments to regions?

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by chimeracoder on Thursday April 12, 2018 @11:33AM (#16821996)
> They weren't compensating them to fill scripts for the generic.

They're not out there to make sales for old drugs (drugs that have gone generic). They're out there to make sales for new drugs, which don't have generic equivalents at all.

No pharmaceutical company is going to waste money on sales for drugs that have gone generic, and certainly no pharmaceutical company is going to try and incentivize providers to DAW prescriptions. Aside from being already illegal, even an unscrupulous company wouldn't bother because it'd be a tremendous waste of money.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by rayiner on Thursday April 12, 2018 @07:22AM (#16819682)
None of those points apply here, where the new branded drug is a revolutionary advancement over the previous drugs. (This non-profits new drug is something newer still).

Saving a life creates some aggregate economic value (the person will not die and instead will continue contributing to the economy for X more years). Drugs are expensive because in the first world, that amount is a lot and the entity creating a cure can reasonably expect to capture a substantial portion of it, either because the person will pay it or because governments will.

Neither is intrinsically a problem. $84,000 to cure HepC is a bargain, because people die from that quite young and on the other side of the equation is potentially millions of dollars of saved economic productivity. That’s not an argument for not charging $84,000 for HepC drugs. It may well be an argument for having the government foot the bill.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by bradleyjg on Thursday April 12, 2018 @08:33AM (#16820168)
It’s important that we incent what we actually want. As it stands the science is often done in universities funded by federal grants. The monopoly owner—which is allowed to capture much of the value—is responsible for the drug testing process and marketing.

The drug testing process is no doubt important but is it so much more important than the initial drug discovery that the entity that funds it should be where all the profits go?

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by rayiner on Thursday April 12, 2018 @11:03AM (#16821642)
That’s a misleading characterization of the industry. There is a huge gap between university research and products people can sell, and its not just drug testing and marketing. (Think of the difference between the Google patent developed at Stanford and Google’s real search engine.)
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by aaavl2821 on Thursday April 12, 2018 @08:47PM (#16826231)
The value of academic findings is only apparent in retrospect, after a drug has been shepherded through the development process by a biopharma company. The govt spends maybe $25-30B a year on drug research. The top 15 pharma companies alone spend like $70B a year on R&D

It costs over $200M to take a drug from academia to market just including out of pocket costs. Including the drugs that fail at various stages within industrial drug dev -- 90%+ of drugs -- and the cost to get a drug approved is $2.6B, not including academic costs

Compounds discovered in academia have like a 1 in 10,000 chance of getting approved. The group that analyzes which of those drugs have a shot at getting to market and funds the cost of that R&D are biopharma companies

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by howard941 on Thursday April 12, 2018 @09:28AM (#16820677)
Reducing life to exploitable profits is just wrong. If it's the only way to incentivize drug testing and marketing then the companies involved in those pursuits ought to struggle under the weight of sin taxes.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by rayiner on Thursday April 12, 2018 @10:58AM (#16821581)
You can ignore economics, but economics won’t ignore you (especially when you do stupid things like tax industries that create a benefit because you deem that benefit too important.)
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by howard941 on Thursday April 12, 2018 @11:42AM (#16822074)
If taxing price gougers seems stupid you're going to hate the pitchfork-toting mobs.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by rayiner on Thursday April 12, 2018 @11:53AM (#16822185)
In litigation, the cost of a decade of life can be valued at a million dollars or more. Saving the life of a 45 year old for $85,000 isn’t “price gouging” it’s a huge bargain. And taxing industries that create those outcomes, like we do with industries we want to discourage (such as alcohol or tobacco) is economically irrational.

Of course you expect the pitchfork-toting mobs to be irrational. But that’s not a basis for arguing in favor of something as a matter of sound policy.

Trying to set drug policy ignoring the economics of human life is like trying to design an airplane while ignoring gravity. You can’t will physics into submission through moral outrage. There is, as far as I can tell, no proven correlation between scientific talent and altruism. If you make it so you can’t get rich saving lives, many of the best and brightest will go work making better advertising technology instead.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by fricat1ve on Thursday April 12, 2018 @12:16PM (#16822392)
You're making this very hand-wavy calculation. Hardly any 45 year olds were dying of hep C, even the older ones had lots of comorbidities & other risk factors, which is what one would expect for a disease acquired through intravenous drug use, and often transmitted in prisons or unsanitary tattoo parlors, and the drugs don't have a perfect cure rate.

In any case it's nearly irrelevant because this was a completely post-hoc rationale for pricing this drug. I am not opposed to large cash bounties for major advances but our current system is not remotely designed around that principle. Forgive me for thinking you are defending the wrong system.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by rayiner on Thursday April 12, 2018 @12:29PM (#16822509)
In one study, 60% of the people who died of Hep-C were between 45 and 59: https://www.hepmag.com/article/death-risk-24659-138388084. More than half of cases aren't the result of intravenous drug use: https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/cl....

> In any case it's nearly irrelevant because this was completely post-hoc rationale for pricing this drug

Drug development, like tech startups, is high risk, but every now and then creates a lot of economic value. To make the system sustainable, there must be a way of capturing a significant chunk of that value from those "unicorns." So yes, it's post hoc in the sense that you don't know until after you roll the decide whether a particular drug is going to create a lot of value or not. That's the case with most high risk investments.

> Forgive me for thinking you are defending the wrong system.

Forgive me for thinking that people are completely nuts for thinking it's a good idea to lower the potential rewards to investment for industries that are "more important." It's completely ass-backward.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by fricat1ve on Thursday April 12, 2018 @01:05PM (#16822872)
Those studies don't say what you're claiming.

I meant the pricing was post-hoc in the sense that they came up with a story like yours for why it was worth $84,000 when they were bringing it to market. There was no precedent for a pill that costly when the research was undertaken. Even in the case of HCV--the best case to be discussing if you're an advocate of for-profit medicine--it's not a good example of an incentive structure.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by refurb on Thursday April 12, 2018 @12:32PM (#16822542)
You need to do a bit more reading. The latest Hep C drugs have cure rates of over 99%. Even NICE, the UK's cost-effectiveness committee said that Sovaldi is cost-effective.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by stale2002 on Thursday April 12, 2018 @12:51PM (#16822722)
Look, if you would rather those companies not even exist in the first place, the cure not invented, and the people suffering from the disease die, then go ahead and say so.

This way, you'd have no one to blame for all the problems.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by inasio on Thursday April 12, 2018 @12:18PM (#16822404)
In the US efficacy is typically measured through estimates of DALYs (disability-adjusted life years). Following WHO guidelines, cost of an intervention (or drug) up to three times the national per-capita GPD (~3x50K in the US) is considered to be cost-effective.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by runamok on Friday April 13, 2018 @11:25AM (#16830844)
That is fascinating. Would love to read more about how this is determined and applied.

To me a big issue is, does this drug cure a condition or merely treat and contain it...?

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by jeffreyrogers on Thursday April 12, 2018 @10:57AM (#16821565)
> But some of it's because nobody in the system seems to have a real incentive to reduce costs

And I think a large part of this stems from insurance companies paying for most of the cost of care (if you're insured) rather than the person who is receiving the care, which leads to a market failure because the insurance companies aren't incentivized to keep costs down like an individual would be.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by my_first_acct on Thursday April 12, 2018 @11:25AM (#16821900)
A couple of problems with the idea of "incentivizing" individuals to keep the cost down, by forcing them to pay more of the cost out-of-pocket (ignoring the moral question of whether people with less money should in fact receive inferior health care):

People will pay almost anything to stay alive and healthy, or to keep their loved ones alive and healthy; few people are willing to turn down the more expensive option even if the increased benefits are minor, and even if it means going bankrupt in the process;

Health-care costs are not very transparent, and bills are often computed after the fact; it is much easier to find out the price and quality of a washing machine, than the price and quality of a doctor. In other words, shopping around (assuming you have time and energy to do that while sick or dying) is not easy.

Rich countries outside of the US manage to spend much less money per capita on health care than the US, with similar health outcomes, and with a much lower rate of people forced into bankruptcy by medical expenses. They don't do this by pushing more of the cost of care onto the patient. Perhaps we in the US should try to learn from them.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by jeffreyrogers on Thursday April 12, 2018 @12:06PM (#16822304)
Yes, I agree. I was just pointing out one reason the current system doesn't control its costs very well. There are lots of potential ways to improve the system, some of which are already implemented in other countries.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by sandworm101 on Thursday April 12, 2018 @07:24AM (#16819690)
"Generic" is a legal term for a drug not subject to patent controls. "Alternative" is a medical/practical term for an alternative drug that may or may not still be under patent.

Alternatives can be cheaper, or useful if a patient cannot tolerate the first choise.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by tssva on Thursday April 12, 2018 @07:51AM (#16819868)
Although most generics are for drugs no longer under patent protection this is not always the case. A more accurate definition of a generic is the one from Wikipedia, "A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance and intended use, but does not carry the brand name. The generic drug may differ from the original in non-essential characteristics such as color, taste and packaging."
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by perseusprime11 on Thursday April 12, 2018 @07:54AM (#16819894)
Incentives! That is 100% the only right answer to healthcare problems in our country.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by croon on Thursday April 12, 2018 @08:14AM (#16820029)
Care to elaborate?

Analogy: How do you get people to win the game? "Reward the winner". Sure, but what's the game, how do you win it, what's the reward, how do you distribute it.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by skookumchuck on Thursday April 12, 2018 @02:28PM (#16823605)
Have a free market in health care. (The U.S. health care market is anything but a free market.)
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by positr0n on Thursday April 12, 2018 @05:55PM (#16825241)
What do you mean by that? I'm sympathetic to making healthcare look more like a free market, but I don't know what a free market in health care looks like.

If you don't have money, society shouldn't just let you die. The second you try to fix that (with government) you don't have a free market.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by skookumchuck on Thursday April 12, 2018 @06:08PM (#16825339)
The US had a free market in health care before the 1960s.

Health care was a lot cheaper then, and charity was available for poor people.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by DoveBrown on Friday April 13, 2018 @06:11AM (#16828502)
And health care was a lot worse in the 1960s and before. Let's not pretend that before the 1960s were some golden age. In 1965 infant mortality was 24.7 deaths per live births, in 2016 it was 4.3.

Sources: 1965 number from: https://www.cdc.gov/nchs/data/series/sr_20/sr20_020acc.pdf 2016 number from: https://en.wikipedia.org/wiki/List_of_countries_by_infant_an...

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by skookumchuck on Friday April 13, 2018 @04:01PM (#16833439)
They've been trending downward in the US since 1800.

https://www2.census.gov/library/publications/1960/compendia/...

You can see by the other stats in the PDF that all measures of health improved dramatically 1800-1960.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by Consultant32452 on Thursday April 12, 2018 @09:50AM (#16820862)
The best case scenario is that each person is empowered to answer those questions themselves. The worst case scenario is to have someone else define for you what winning is and how you should go about doing it.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by croon on Thursday April 12, 2018 @01:12PM (#16822935)
That's somehow even more vague than GP. I think the issue is pretty clear: The US has too expensive healthcare, and too low quality in relation to that price.

The solution "incentives" isn't really constructive in solving that issue, if you don't suggest what those incentives are.

And as for your comment: within this problem space, everyone defining their own healthcare system and solving it is even less constructive.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by Consultant32452 on Thursday April 12, 2018 @01:20PM (#16823008)
The point is that the "healthcare system" should be an emergent one where each person is maximally in control of their own destiny. The idea that a few wealthy, connected, buyable people could get to "define the healthcare system" is terrifying.
Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by croon on Thursday April 12, 2018 @01:56PM (#16823294)
I think you're describing a separate problem, of campaign financing, lobbying and/or corruption.

> The point is that the "healthcare system" should be an emergent one where each person is maximally in control of their own destiny.

Again, this is a nice sounding platitude. What does it mean? Since you want everyone to be "maximally in control", does that mean Mad Max-style anarchy? Representative democracy ensuring everyone gets a voice and securing of rights?

Both ensures freedoms, but in very different directions.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by Consultant32452 on Thursday April 12, 2018 @02:11PM (#16823439)
Mad Max isn't anarchy, it's a centralized authoritarian dictatorship. What you're talking about where you want me to suggest a definition of "the game," how it's played, how to win, etc. is closer to Mad Max.

With regards to healthcare, the best system is one in which each individual person has autonomy over themselves. Each will have its own desires: making money, saving money, receiving treatment, etc. The "system" emerges from the accumulation of human desires and abilities. I can't tell you exactly what it looks like because I can't pretend to know what everyone will want, nor can I tell you what is best for everyone. They are best left to determine that themselves.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by croon on Thursday April 12, 2018 @02:19PM (#16823520)
Mad Max was anarcho-capitalism reaching its logical conclusion, a monopoly with a financed militia.

> With regards to healthcare, the best system is one in which each individual person has autonomy over themselves. Each will have its own desires: making money, saving money, receiving treatment, etc. The "system" emerges from the accumulation of human desires and abilities. I can't tell you exactly what it looks like because I can't pretend to know what everyone will want, nor can I tell you what is best for everyone. They are best left to determine that themselves.

So basically no health care system and no social security, and bartering for whatever you want.

Just say you want libertarian minimal government and we'd have saved 10 minutes of our lives instead of vague platitudes.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by Consultant32452 on Thursday April 12, 2018 @02:45PM (#16823748)
>Mad Max was anarcho-capitalism reaching its logical conclusion, a monopoly with a financed militia.

Authoritarianism comes in many stripes. Capitalism can be authoritarian, but forced socialism always is.

>So basically no health care system and no social security, and bartering for whatever you want.

Emergent systems exist all over the place. The very language we're using right now to communicate is an emergent system. There is not a central authority which dictates how we must converse, and yet here we are.

>Just say you want libertarian minimal government and we'd have saved 10 minutes of our lives instead of vague platitudes.

I didn't try to give you a platitude. You wanted me to define what is best for everyone and I tried to show you that your question implies that authoritarianism is best. I disagree with your implication.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by croon on Thursday April 12, 2018 @04:03PM (#16824436)
> I didn't try to give you a platitude. You wanted me to define what is best for everyone and I tried to show you that your question implies that authoritarianism is best. I disagree with your implication.

Cooperation and synergy isn't the same as authoritarianism. There's a reason that civilization and societies reached all major advances and discoveries, and not hermits or tribes.

There's immense value in limiting overhead by delegating fundamental services into a collective pool.

But all that is besides the point. On topic:

I wanted neither you or OP to define what is best, I wanted OP to clarify what he was suggesting since he was suggesting something. I wanted you to clarify what you were saying, since I didn't understand how it fit into my response to OP. Apparently it didn't.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by Consultant32452 on Thursday April 12, 2018 @04:24PM (#16824622)
>Cooperation and synergy isn't the same as authoritarianism. There's a reason that civilization and societies reached all major advances and discoveries, and not hermits or tribes.

You explicitly asked questions like, "how do you get people to win the game?" "How do you win it?" "What's the reward?" "How do you distribute it?"

In other words, you wanted us to dictate what "winning" means, what the rewards are for winning, and how the rewards would be distributed. That's not cooperation, that's dictation. Each person may have their own definition of winning and as long as they're not infringing on the rights of another, they can do whatever they wish to accomplish their goal.

>There's immense value in limiting overhead by delegating fundamental services into a collective pool.

Please don't forcibly dictate to me what is valuable by forcing me into a system that maximizes what you personally find valuable. I will offer the same kindness in return. That is the crux of the problem with the set of questions you asked originally and why what I've said does fit into your response to OP.

Re:Non-profit’s $300 hepatitis C cure as effective as $84k a... by croon on Thursday April 12, 2018 @04:44PM (#16824782)
Since you bothered to reply, and completely ignored the paragraph that answered your (now repeated) comment, I have to assume that you're not here for a genuine discussion.