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Re:What If PTSD Is More Physical Than Psychological? Evidenc... by Madmallard on Saturday June 11, 2016 @03:01PM (#11884788)
Or, get this, and this is super radical of an idea I know:

There is not much of a separation between physical and psychological in the first place. Every part of the body is interconnected--as people develop disease, often times mental symptoms develop secondarily so. Depression and anxiety are super common in all sorts of illness states. There are numerous studies showing cellular dysfunction and rampant oxidative stress connecting to the more serious mental illnesses.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by bcarlyle on Saturday June 11, 2016 @09:28PM (#11886214)
The idea of a divide between mind and body is strange.

It seems like our consciousness is constructed in such a way that it's very easy for people to forget that we actually have a body connected to our head.

Another interesting idea would be to think that mental health problems in part are caused by the systems inside our body that are outside of our conscious control not working properly communicating their discomfort as mental health problems.

I'm a clinical psychologist and I don't think I've had a patient in therapy who had

1. Sleep 2. Exercise 3. Stress 4. Food

Figured out.

What I mostly notice is that once these things are improved the need for therapy diminish significantly.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by dunmalg on Saturday June 11, 2016 @11:32PM (#11886489)
"What I mostly notice is that once these things are improved the need for therapy diminish significantly."

Isn't this sort of a chicken-egg problem? I have horrible sleep issues, but they're caused by PTSD related anxiety, and yes, the insomnia then exacerbates the anxiety. I sleep better when my anxiety is under control, but it's not the good sleep that reduces my anxiety--- it's stuff like Xanax and meditation.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by rdtsc on Saturday June 11, 2016 @11:38PM (#11886514)
> The idea of a divide between mind and body is strange.

I think that is an important construct. It allows us to abstract the notion of an individual and make it something well above a bag of bones and meat. By "above" I mean something superior, trancendant, more important.

A lot of religions have the concept of a soul, and due to Abrahahim religions, the West that concept persisted. Even if people don't believe in a soul there is still a concept of a mind as separate from the body.

In computer terms (because it is hacker news), there is a tempting analogy of software and hardware. The mind / self / personality / soul is the software. The body is the hardware. Of course, we know that software is stored by altering some parts of the hardware (electric charges, etc)). So there is a connection obviously, but we still talk about it as separate things.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by nikdaheratik on Monday June 13, 2016 @11:30PM (#11899553)
It's not just religious traditions that continue this idea. Ancient Greek philosophy kicked this off as well. To be fair, this separation makes alot of thought easier/possible. But considering how much we don't know about the brain or how consciousness works, it may not be the best way to promote mental and physical health.
Re:What If PTSD Is More Physical Than Psychological? Evidenc... by adammunich on Saturday June 11, 2016 @03:34PM (#11884952)
I never understood why people rarely take this approach. It's not as if these things occur in isolation.
Re:What If PTSD Is More Physical Than Psychological? Evidenc... by SolaceQuantum on Saturday June 11, 2016 @03:41PM (#11884983)
There is a long medical history of treating things in isolation in order to understand fundamental aspects of biology and such. While the rest of science has more or less moved on from this mindset, the medical field hasn't fully yet.
Re:What If PTSD Is More Physical Than Psychological? Evidenc... by kordless on Saturday June 11, 2016 @08:35PM (#11886091)
It's called measuring things. It's what we do, after all.
Re:What If PTSD Is More Physical Than Psychological? Evidenc... by MarkPNeyer on Saturday June 11, 2016 @11:33PM (#11886494)
Measurement is great. I'm all for it.

But there's a serious problem with scientism in the modern world. I think it's great to develop a way of looking at the world that 'takes people out' - we can predict the motion of the moon without regard to what people think or feel about how the moon will move. The moon's motion does not take our feelings into account.

It starts to get really silly, though, when you try to use those same techniques to look at people. "How do people behave, in the absense of people" is a very silly question to ask, but it seems like that's what we try to do when we look at people through the lens of modern scientific methods.

Every person is different and has a different personal history. The idea that you can formulate some 'general rule' for how people behave is as baseless as trying to come up with a 'general rule' for computers.

It makes much more sense to look at different software patterns and how they operate, rather than trying to snip a transistor and then see how the graphical output changes, which is effectively what we do in mental health medicine.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by kordless on Sunday June 12, 2016 @03:10PM (#11889730)
The problem you are referring to is known, although I'm not sure how widely spread.

You can't measure the measurer, so there's a gap in our perception. There's a RI talk on this, where the color purple is discussed. There's really no color purple, for example. It's your eye picking up the absence of green when seeing blue and red light together.

In other words, perhaps purple is a program in your head.

Perhaps our ability to understand the nature of a measurement is an absence of something we yet to integrate into our knowledge base? My vote is for a momentary access to the global consciousness. Like an API with a "search" timer on it. It serves efficient queries faster. It does this in a fixed timeframe using a hierarchical form of evaluation. It knows everything it knows so far.

In other words, perhaps causality in this reality is based on some type of immutable programmable storage. Perhaps that' why it's hard to change things here too.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by digi_owl on Saturday June 11, 2016 @04:30PM (#11885196)
Mind-body duality have been a strong force in human society.

Heck, swap mind with soul and you may trace it as far back as we have "documented" history.

We have this strong resistance against seeing our thoughts, feelings and such as signal activity between a massive bundle of cells.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by DanBC on Saturday June 11, 2016 @05:45PM (#11885476)
It's not that rare - it's made it to UK government national strategy advice over five years ago in "No Health Without Mental Health" which talks about the importance of improving physical health for people with mental illness[1] and improving mental health for people with physical illness.

[1] for a variety of reasons people with severe mental illness die about 20 years earlier than the general population.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by jeffdavis on Saturday June 11, 2016 @11:34PM (#11886497)
The more complex a theory is, the harder it is to draw useful conclusions that people can actually apply.
Re:What If PTSD Is More Physical Than Psychological? Evidenc... by PeterisP on Saturday June 11, 2016 @05:20PM (#11885387)
It's not so simple - while it is obvious that physical damage to the brain can cause psychological damage to the mind (e.g. lobotomy), it's not clear (at least to me) if purely psychological damage (e.g. horrific emotional events, war situations with no physical effect to you) can disrupt the physical functioning of the brain.

Change in balance of some neurotransmitters can cause symptoms of mental illness - but can purely psychological events (i.e. what you observe and contemplate) cause permanent alterations to that chemical balance, cellular dysfunction, structural damage in the brain, etc?

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by cpncrunch on Saturday June 11, 2016 @07:27PM (#11885883)
Yes, it is pretty well established that cortisol causes the hippocampus to shrink [1]. Studies also show that the hippocampus shrinkage in PTSD is reversible with treatment [2].

That is just one example, but there are quite a lot of other long-term structural changes in the brain after chronic stress.

[1] http://www.biologicalpsychiatryjournal.com/article/S0006-322... [2] http://www.biologicalpsychiatryjournal.com/article/0006-3223...

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by Mz on Saturday June 11, 2016 @05:49PM (#11885492)
When he was really little, my oldest son was prone to having tantrums. When he was four years old, he was literally hopping mad one day and this resulted in him literally bursting a blood vessel. He developed a sudden, really severe nosebleed. He was prone to nosebleeds anyway, but this was one of the worst ones he ever had and I was concerned for a bit that I would need to take him to the ER because I had trouble getting it to stop, in spite of experience and knowledge about this issue.

The experience was incredibly shocking for him. The idea that his feelings could actually cause him direct physical harm really freaked him out. Furthermore, the event caused his tantrum to end very suddenly. The tantrum came to a screeching halt, so to speak. Without any training, he was able to use this experience as a form of biofeedback. He had felt something in his brain when it stopped and that allowed him to find some means to interrupt the runaway process at subsequent events.

He didn't like being mad, so being mad made him mad about the fact that he was mad and it created a positive feedback look that caused his anger to just go off the rails. He stopped having tantrums following this incident.

I think, yes, psychological things can literally have direct physical impact. We know it can do things like raise your blood pressure. This is an ordinary thing. With extreme enough experiences, I see no reason why it wouldn't impact the brain in a meaningful way with long term consequences

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by didgeoridoo on Saturday June 11, 2016 @05:36PM (#11885454)
Yes. Psychological trauma can result in repeated and excessive flooding of the synapses with neurotransmitters, which can cause lasting physical damage much like drug abuse can.
Re:What If PTSD Is More Physical Than Psychological? Evidenc... by rntz on Saturday June 11, 2016 @05:32PM (#11885431)
If a permanent change in your psychology did not correspond with some permanent change in your physical person, then what would there be that was causing the change in your psychology? Some non-physical "soul" or "mind"?

All psychological facts have physical correlates (in philosophy of mind, this is called "supervenience"). The only limit is our ability to measure things. As our ability to measure our own brains and bodies increases, we should expect to uncover more and more physical correlates of psychological conditions.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by PeterisP on Saturday June 11, 2016 @06:09PM (#11885581)
As I said, the question (answered by others) is about structural changes. Any memory is formed by changing something in the brain, but forming this memory doesn't cause any meaningful changes to the general physical functioning of the brain; forming memories and having preferences (and changing them!) is what the brain does; perhaps the quantity of memories affects the structure of the brain or alters its functioning/learning, but generally the content of memories will not.

Psychological facts having physical correlates isn't the answer - to use a wrong-but-useful analogy; it's clear that hardware can inappropriately alter/damage software in many different ways, but in what ways software can/cannot damage or alter the normal functioning of the hardware? The other answers give some examples where this can happen - are there more direct ways?

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by Razengan on Saturday June 11, 2016 @08:02PM (#11885993)
> it's clear that hardware can inappropriately alter/damage software in many different ways, but in what ways software can/cannot damage or alter the normal functioning of the hardware?

I see where you're coming from, but in the case of biological brains and their physiology, the hardware IS the software, no?

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by DougWebb on Saturday June 11, 2016 @06:18PM (#11885610)
forming this memory doesn't cause any meaningful changes to the general physical functioning of the brain

Maybe not any that we are currently able to measure, but something's got to be changing. As an analogy, consider your computer: you could open it up, look inside, and feel that temperatures of different parts change over time, but you can't tell what it's doing or how well it is working just by looking at it. Even with fancy electrical equipment you'd have a hard time determining what's going on, beyond detecting that there's a lot of signal activity flowing around. To really see what's happening you need access through the software, and we just don't have that kind of access to the human mind.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by PeterisP on Saturday June 11, 2016 @06:35PM (#11885685)
I still don't understand if you're really claiming what I feel you're claiming, that is, saying that "forming this memory doesn't cause any meaningful changes to the general physical functioning of the brain" is false?

It's not a question of being able to measure - I believe that we can measure e.g. synapses being strengthened and weakened as a result of learning skills; but that these changes don't change the physical functioning; it's just part of their normal functioning and it functioned exactly as well before and after - the behavior is different but physically equivalent.

For what I mean as a "meaningful change to the physical functioning", consider your computer - deleting all the software and installing a different operating system would not be a meaningful change to the physical functioning; the temperatures, electric charge and magnetic properties of the involved parts would be very different, but that doesn't matter as all the physical parts would still function in the same normal way although the screen would be displaying very different signals.

On the other hand, a software program that manages to physically disable or re-enable parts of some chip in a way that's not normally possible through software, blow a fuse in a hard drive or trigger a processor bug that "bricks" the processor - those would be the kind of changes to the general physical functioning I'm talking about. In what cases do we have such changes to the physical functioning of (parts of) the brain? Changes that are substantially different from any changes that the brain "does to itself" in the course of normal operation?

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by DanBC on Saturday June 11, 2016 @06:45PM (#11885733)
https://www.researchgate.net/profile/Eric_Vermetten/publicat...

> Borderline personality disorder (BPD) is a common disorder associated with emotional dysregulation and other symptoms that have been hypothesized to be related to dysfunction of limbic brain areas including hippocampus and amygdala. The purpose ofthis study was to measure hippocampal and amygdala volumes in BPD. Hippocampal and amygdala volumes were measured with magnetic resonance imaging (MRI) in 10 patients with BPD and 23 control subjects. Patients with BPD had a 21.9% smaller mean amygdala volume and a 13.1% smaller hippocampal volume, compared to controls. These findings are consistent with the hypothesis that alterations in the hippocampus and amygdala are associated with BPD.

Here they see changes in the structure of the brain.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by PeterisP on Saturday June 11, 2016 @07:10PM (#11885824)
Actually, not really, the paper doesn't say that - it seems to explicitly limit its findings to an association and nothing more.

They see changes in the structure of the brain and they see changes in behavior (BPD), but they're clearly not saying that BPD caused these structural changes - they list both causal directions as some of possible hypothesis (altered amygdala/hippocampus causing BPD and/or BPD-related experiences causing these alterations in amygdala/hippocampus), in addition to other possible scenarios e.g. the fact that all of their BPD-group was on psychotropic drugs could also have been a cause for the observed changes, etc. They also aren't making any conclusions about a possible link between childhood abuse and BPD (or link between abuse and these brain changes) beyond the fact that they chose a set of 10 subjects that all had both BPD and suffered abuse; they're not even discussing a correlation as their data isn't sufficient to say anything about that.

All the observations in this paper certainly are compatible with a hypothetical scenario where these brain changes cause BPD (or indeed, are BPD) but it was some factor other than emotional trauma that caused the observed changes in their brains. I don't know if it is that way, but this particular paper also doesn't give any evidence to support or deny it.

[edit] It even seems that they don't even state that there was a change in their brains - instead, they observe a difference between BPD patients and the control group; but it would also be consistent with a hypothesis that these patients had smaller hippocampus/amygdala e.g. since birth, and simply having that property (instead of a change) was a risk factor predisposing them to suffering BPD symptoms later in life; and the authors acknowledge this as a possible option in their conclusions.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by Dylan16807 on Saturday June 11, 2016 @07:04PM (#11885804)
Yes, a lot of disorders involve physical changes. But that doesn't tell us if the physical changes are cause, effect, or both wrt the mental changes.

The question at hand is whether you can have thought patterns that cause structural/functional changes to happen.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by Retric on Saturday June 11, 2016 @07:26PM (#11885878)
Emotions are generally non local chemical releases in the brain. Stress, fear, love, hate, all bathe most of the brain in the relevant chemical cocktail. So, no it's more than just local memory formation.

On that note, memory's footprint is all over the brain. Learning judo is more than just filling up a psudo HDD with relevant information.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by nikdaheratik on Monday June 13, 2016 @11:36PM (#11899573)
The problem with looking it this way is you are ignoring another thing the brain does, which is to link events in memory with emotions, and triggering these emotional responses in turn release all kinds of chemicals that affect the way the brain functions.

Granted this link fades over time (and likely therapy helps), but the body is not always good at handling major stresses and the damage can become permanent.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by nommm-nommm on Saturday June 11, 2016 @05:42PM (#11885468)
>can purely psychological events (i.e. what you observe and contemplate) cause permanent alterations to that chemical balance, cellular dysfunction, structural damage in the brain, etc?

I think so. Amblyopia is an example of structural changes in the brain based on what you observe. It generally happens early in life when the brain is more plastic but it proves it is possible. There is also evidence that amblyopia may be able to be treated in adulthood.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by DanBC on Saturday June 11, 2016 @05:42PM (#11885466)
They've put people who've had extreme childhood abuse into brain scanners, and seen differences in the amygdala.

I think they took a different group of people and predicted differences in the amygdala based on psychologic symptoms, and then checked that in MRI scans, and found the differences they predicted. (Although I'm having trouble find the links at the moment.)

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by riprowan on Saturday June 11, 2016 @06:05PM (#11885565)
Isn't it well-established that learning of any sort produces physical change in the brain?

Why would experienced trauma be any different from any other extremely powerful (and repeated) (yet traumatic) learning experience, thus causing permanent change in the brain to "capture" and "remember" the incident like any other powerful learning experience?

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by PeterisP on Saturday June 11, 2016 @06:19PM (#11885615)
Learning a fact physically "records" the fact in the brain, but is it well-established that powerful learning experiences can cause changes to the overall functioning of the brain?

I mean, not the physical changes that amount to "now your motor neurons have changed so that they swing a golf club more accurately" but physical changes that are like "now your motor system or learning system or the regulation of something seemingly unrelated is structurally different because you've been seeing/hearing/thinking these things" ?

I'm not talking about a memory "subsystem" being changed so that it now contains and remembers the incident; that's the usual function of it; I'm talking about the memory (or other) subsystem being changed so that it is now somehow fundamentally altered, processes things differently from its normal function, or fails to process something that it could before.

Re:What If PTSD Is More Physical Than Psychological? Evidenc... by riprowan on Saturday June 11, 2016 @10:02PM (#11886295)
I'm sorry, I fail to see the distinction you are trying to draw.
Re:What If PTSD Is More Physical Than Psychological? Evidenc... by tudorw on Saturday June 11, 2016 @04:59PM (#11885295)
Quantum Biology looks interesting, I'm in no way qualified to opine, yet I am fairly confident we're still a long way from a complete understanding of body and mind!
Re:What If PTSD Is More Physical Than Psychological? Evidenc... by rntz on Saturday June 11, 2016 @05:21PM (#11885389)
Although this is true, learning that there is a specific physical sign in the brains of those who have suffered blasts at close range, and that this sign is not present in those who have suffered other forms of stress, is a significant breakthrough!

The article presents this as an issue of physical vs. psychological, but even stripped of that misconception it's still an interesting article.