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Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Bender on Friday November 13, 2026 @09:08AM (#50483711)
Maybe there are people permitted to speak about science and medicine with Claude but any time I tried I would get my session [bio] locked. I take those discussions to Gemini that is perfectly willing to discuss epigenetics, supplements, peptides, cell reprogramming, etc... What other LLM's are people using for such discussions and analysis?
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by jostmey on Friday November 13, 2026 @09:12AM (#50483773)
It makes me laugh how Claude is going to usher in this new air of medicine when you can’t even use it for biomedical research – – I’ve tried
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by ceejayoz on Friday November 13, 2026 @09:14AM (#50483798)
Let's be fair here - Anthropic clearly wants to provide less guarded models like Mythos, not Fable. They'd likely willingly provide such things to large pharmaceutical companies in a way us regular users will never be privy to.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Bender on Friday November 13, 2026 @09:24AM (#50483942)
[delayed]
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by HDThoreaun on Friday November 13, 2026 @09:35AM (#50484119)
I mean just take a look at twitter to see all the crazy shit people come up with to try to trick models into bypassing the guardrails. Do you honestly believe that if they allowed defensive cybersecurity analysis people wouldnt figure out how to turn that into offensive cybersecurity analysis? I think they just really dont want to be blamed when someone releases malware written by AI
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Bender on Friday November 13, 2026 @09:45AM (#50484274)
I've had zero issues with defensive secure coding with Grok. It's model is not as powerful as Opus 5.5 but honestly that's fine. I would rather have a decent secure solution than something shiny and insecure. All I can see is Anthropic trying to up-sell a product as if security was a value-add. I disagree with Anthropic, secure code is a mandatory part of software development.

As for people tricking the LLM, instead of blocking people I say empower them and just silently expose malicious behavior to Palantir and PRISM like everyone else does. Want to hack an airline or build a dirty-bomb? Give them 80%-90% of the steps they need and let someone kick down their door. The LLM should not be getting in the way to any of that. Google from day-1 has monitored user intentions and behavior rather than blocking it and I think that is the better path to take (monitoring exposing those that have malicious intentions).

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by ceejayoz on Friday November 13, 2026 @09:53AM (#50484414)
> I say empower them and just silently expose malicious behavior to Palantir and PRISM like everyone else does.

Automated SWATting at scale? Sounds unfun.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Bender on Friday November 13, 2026 @10:06AM (#50484619)
It's called Total Information Awareness. Not swatting, analyzing who is:

- radicalized

- has verifiable intentions

- clever/intelligent enough to pull it off

LLM's would be the perfect tool to filter down the millions of people requesting dumb things into a small group of actual threats.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by ceejayoz on Friday November 13, 2026 @10:56AM (#50485396)
LLM's would be the perfect tool to generate a whole bunch of false positives someone's gonna just skim over, click approve, and get innocents murdered because they were trying to get their plutonium processing working in the game Satisfactory.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by HDThoreaun on Friday November 13, 2026 @09:54AM (#50484432)
Ok but to me this just means that someone is going to use grok to create malware. I do not think that means anthropic should also let people use their product to create malware. Monitoring interactions isnt exactly foolproof. The user has already convinced the AI that its doing defensive cybersecurity here. If the claim is that anthropic is more interested in protecting their image than actually reducing cyber crime, sure I agree with that. But Im not sure thats a terrible thing.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Bender on Friday November 13, 2026 @10:08AM (#50484657)
Grok will refuse to create any offensive security related code which in my opinion is the right balance. I do not believe Anthropic is about protecting their image [1] but rather up-selling enterprise features.

[1] - https://www.youtube.com/watch?v=4BnLL7tUGmI

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by HDThoreaun on Friday November 13, 2026 @10:37AM (#50485076)
Grok will try to refuse any offensive cybersecurity work but it’s too easy to disguise offensive work as defensive work. I don’t think it is possible to devise an algorithm that allows defensive work but not offensive work with high certainty.

I guess I don’t see why other models doing bad things means Anthropic should let Claude do bad things too. Anthropic will get blamed if Claude builds malware. They won’t get blamed if grok or deepseek does.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Wowfunhappy on Friday November 13, 2026 @09:54AM (#50484435)
Imagine if in 2022, we restricted educational cybersecurity resources because we were concerned that more people who knew how to program in this domain would lead to more malware.

I mean, I'm sure that's actually true in a sense, but it would also mean fewer people who could fix vulnerabilities.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by alyeska2 on Friday November 13, 2026 @09:33AM (#50484088)
Ridiculous comparison. This is like saying Eli Lilly and Pfizer will never produce medicines because every time you personally show up to do research in their labs they won't let you past the lobby.

The technology has the capability, they're just gating who has access.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by yasnu5 on Friday November 13, 2026 @09:35AM (#50484128)
Anyone with two braincells to run together saw this coming a mile away.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by dd8601fn on Friday November 13, 2026 @09:36AM (#50484147)
Claude safety-downgraded me for asking how to decrypt a folder it knew was mine, using a password I already knew.

I know it’s not the models themselves, but their preflight safety classifiers are a dumpster fire and serious impediment to performing regular work.

That situation can’t go on forever if they’re going to be a competitive service.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by rebolek on Friday November 13, 2026 @09:50AM (#50484366)
It's fucking depressing. I have a skill that says it's ok to connect to a test server on VPN that gets wiped out each midnight with user/password and it works on Monday but is blocked on Tuesday with some idiotic excuse like credentials exploration or whatever.

And then I tell it to connect to a SSH server it knows nothing about and it's like sure, why not?

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by BeetleB on Friday November 13, 2026 @10:17AM (#50484788)
> but their preflight safety classifiers are a dumpster fire

Even more annoying: They can be easy to subvert.

I was running something at work that involved an LLM, and kept getting safety refusals. The weird thing was that when I went to our in-house chatbot, set the model to the same one the program was using, entered the same text, it happily answered.

I spent quite a while trying to figure out why my program was being refused. Was I doing something wrong?

No - the chatbot was doing something "right". You see, the chatbot had some tools it injected into the prompt (current time, etc).

So I went back to my program and injected the same tools. Suddenly my request was very safe.

The phrase "security theater" was invented for stuff like this.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Obscurity4340 on Friday November 13, 2026 @04:31PM (#50490067)
I switched to DeepSeek flash v 4 something and the difference could not be starker. And I never seem to run out of "tokens" even at the highest reasoning level on all the time
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by drngdds on Friday November 13, 2026 @09:59AM (#50484519)
You can use it for biomedical research if you need to https://www.anthropic.com/news/life-sciences-verification-pr...
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by miltonlost on Friday November 13, 2026 @09:57AM (#50484483)
oh god, peptides... biohacking with AI is not a good thing to do. Self-diagnosis of a medical condition using a chatbot is already bad.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Marha01 on Friday November 13, 2026 @10:04AM (#50484594)
> Self-diagnosis of a medical condition using a chatbot is already bad.

Tell that to my (now solved) health issue, which was correctly diagnosed by Gemini, while a real doctor failed to find the cause.

Diagnosis is the one thing where today's AI is actually very good.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by BeetleB on Friday November 13, 2026 @10:14AM (#50484738)
> Tell that to my (now solved) health issue

Tell that to Jack, who overdosed on a medication.

Oh, you can't. Jack is dead.

I don't think anyone is claiming you can't get good advice from a chatbot. They're saying you could also get terrible advice.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Marha01 on Friday November 13, 2026 @10:20AM (#50484839)
> I don't think anyone is claiming you can't get good advice from a chatbot. They're saying you could also get terrible advice.

Yes. But you could also get terrible advice from a doctor. The important question is: what are the relative probabilities of good/bad advice, if you compare a frontier LLM to an average doctor?

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by gyesxnuibh on Friday November 13, 2026 @10:37AM (#50485078)
Good luck suing an LLM for malpractice
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by aucisson_masque on Friday November 13, 2026 @10:52AM (#50485323)
LLM answers to your question as long as you want.

Doctor is 10 minutes, doesn’t listen and then 6 month for new appointment.

The choice is easy, LLM to explore. Doctors to prescribe.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by easychris on Friday November 13, 2026 @10:57AM (#50485406)
Good luck suing a doctor for it.
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by BeetleB on Friday November 13, 2026 @11:43AM (#50486071)
> But you could also get terrible advice from a doctor. The important question is: what are the relative probabilities of good/bad advice, if you compare a frontier LLM to an average doctor?

Fair point. I haven't queried LLMs for medical advice myself, so I can't compare.

For doctors, I must be an outlier who's been happy with almost all the advice I've been given. And it wasn't blind trust. I've argued with them and even sought second opinions. They always turned out to be right.

Well, technically there have been a few cases where different doctors came up with different diagnoses, but to me the LLM would just be "yet another doctor with yet another differing diagnosis". Never resolved those cases - some still haven't been resolved (i.e. issue remains, so in a sense they were all wrong). Others got resolved but it wasn't clear which, if any, of the doctors were right - it may well have resolved on its own.

Now nurses and physical therapists ... that's a different story.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Bender on Friday November 13, 2026 @10:17AM (#50484777)
Tell that to my (now solved) health issue

Same here. Local doctors do not even know what my issue is. If I had kept relying on them I would not be here right now. LLM's gave me actionable paths to treat my issue and I have had great success. It's going to be a long unpleasant road but at least there is light at the end of the tunnel.

Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by Arodex on Friday November 13, 2026 @12:31PM (#50486765)
I asked the AI if my child would be a boy or a girl. It answered correctly. Clearly AI is able to predict the future!
Re:Eli Lilly CEO pushes back on Dario Amodei's ludicrous med... by margalabargala on Friday November 13, 2026 @10:04AM (#50484599)
In fairness most peptides are inert and harmless.