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Re:Creatine uptake enhances antitumor immunity by flossly on Thursday September 24, 2026 @02:52PM (#49835229)
Why especially those?
Re:Creatine uptake enhances antitumor immunity by dgacmu on Thursday September 24, 2026 @03:01PM (#49835362)
Your body can synthesize creatine, so it's not essential, but meat is a source of exogenous creatine and eating it results in higher stored creatine levels, which is slightly good for muscle power endurance in the ~5-15 second effort range. Supplementing produces slightly higher relative improvements in creatine levels in vegetarians and vegans than it does in people who eat meat.
Re:Creatine uptake enhances antitumor immunity by eknkc on Thursday September 24, 2026 @02:55PM (#49835266)
Nobody gets fired for supplementing vegans.
Re:Creatine uptake enhances antitumor immunity by hobo123 on Thursday September 24, 2026 @02:56PM (#49835283)
Because they lack all kinds of substances that meateaters get plenty of.
Re:Creatine uptake enhances antitumor immunity by SmasherEpilepti on Thursday September 24, 2026 @03:26PM (#49835678)
I'm a vegan, and I'm surprised this is downvoted, because it's true. There are plenty of things that you need to be careful to not become deficient in on a vegan diet: protein (in appropriate amino acid balances), creatine, b12, the good Omega 3s (from algae preferably; flax is missing DHA entirely), calcium, iron, to name a few.

You're fine if you take daily algae oil, multivitamin, iron supplement, calcium, and creatine (without going overboard on any of it) and making sure to get lots of protein from balanced sources (eating a ton of soy is actually not a bad idea, because it's a balanced protein), but I wouldn't recommend somebody who doesn't want to have to worry about their nutrition to go vegan. Enough omnivores are already deficient in vitamins and minerals, and veganism only makes it harder.

Re:Creatine uptake enhances antitumor immunity by hobo123 on Friday September 25, 2026 @12:31AM (#49840215)
Thank you, and don't forget zinc.

Also have to be careful that your protein sources (mainly legume-derived?) don't have too much copper, nickel, heavy metals.

I have no beef (sorry not sorry) with vegans or vegetarians, but indeed, be careful with your nutrition.

Re:Creatine uptake enhances antitumor immunity by hobo123 on Friday September 25, 2026 @01:04AM (#49840371)
Forgot that vegans also tend to get tons of carotene, which even though the body downregulates conversion to retinol, isn't great (but omnivores and vegetarians also often overdo dairy so there's that).
Re:Creatine uptake enhances antitumor immunity by flossly on Monday September 28, 2026 @06:22AM (#49875859)
If I just look around me, i see my omni friends and fam all struggling with overweight and some have expressed problems with constipation and high-BP.

Myself OTOH, lean, low-BP (without any bad symptoms), dont even know what constipation should feel like.

Re:Creatine uptake enhances antitumor immunity by flossly on Friday September 25, 2026 @11:48AM (#49846206)
I dont believe you protein remark. Protein deficiency is virtually unheard of.

I consider creatine and O3s a bio-hack more than a supplementation.

B12: yes. But most meat people eat has been fed a B12 supplement as well (as live stock do not live on dark soil that is abundant in B12; they live on concrete floors and eat factory-produced animal feed... with B12 added to it).

Calcium: nope. Magnesium is more important IMHO; IFF you do not get 2 portions of low-oxelate (most are low-oxelate) leaves per day. I try to get the leaves.

Iron: mostly a thing for menstruating women.

Zink: mostly a thing for ejaculating men.

As a vegan (for moral reasons) I take D3, B12, some Magnesium and sometimes Zink as supplements. I do bio hack myself: creatine, high DHA O3s, but also recreational/experimental drugs.

I agree veganism makes it harder. But I dont think that's what veganism is about: it is an ethical stance. If you are "eating a vegan-compatible diet, but not vegan" we should use another word: plant based diet (which includes fungi, yes, weird).

Re:Creatine uptake enhances antitumor immunity by HedonicEscal8r on Friday September 25, 2026 @02:43PM (#49848352)
This is false, it's only B12 you need to supplement (and meat-eaters also get B12 through supplements, just indirectly).

Most people are not deficient in vitamins and minerals - the benefits of supplementing are highly exaggerated. Evidence is not good.

Re:Creatine uptake enhances antitumor immunity by flossly on Monday September 28, 2026 @06:19AM (#49875838)
I beg to differ. Magnesium and vitD (especially in colder climates, or for indoorsy people) deficiencies are very, very, common.

There's lots of research on this.

Re:Creatine uptake enhances antitumor immunity by iamdev on Thursday September 24, 2026 @02:58PM (#49835312)
Because meat is the best source of creatine from diet.
Re:Creatine uptake enhances antitumor immunity by hagbard_c on Thursday September 24, 2026 @02:58PM (#49835320)
Well, if vegetarians and those of the Vegan religion don't get enough creatine it is most likely related to them not partaking of an important source of the substance: meat.
Re:Creatine uptake enhances antitumor immunity by unethical_ban on Thursday September 24, 2026 @02:56PM (#49835284)
Not vouching for creatine, but in general, humans get some vital nutrients from animal consumption. Vegans have to take some B-vitamins for best health due to what they don't get from meat. I assume creatine is the same.
Re:Creatine uptake enhances antitumor immunity by the_gastropod on Thursday September 24, 2026 @04:56PM (#49836619)
Where do those animals get their B12 from, do you think? (Hint: they don't synthesize it either, they get it from their diet)

Today, because our food / water are so sterilized (good thing!), we don't typically get much bacterial B12 from unclean root vegetables, drinking from streams, etc. So yes, we need to supplement today. Because of advances in cleanliness.

Re:Creatine uptake enhances antitumor immunity by flossly on Friday September 25, 2026 @11:50AM (#49846220)
B12 is about hygiene (not drinking from muddy puddles), not about an inherent problem with veganism.
Re:Creatine uptake enhances antitumor immunity by naishoya on Saturday October 03, 2026 @11:19AM (#49945059)
Ruminants (cattle, sheep, and goats) get B12 from bacteria which are the primary digesting organisms in multistage stomachs, and which are absorbed in the upper (small) intestine, given feedstock with sufficient cobalt nutrient from the soil in which it was grown. Any B12 produced in human digestive tract occurs in the lower (large) intestine which is too late for absorption into the circulatory system of vitamins and nutrients. This means that what trace production may be produced in human digestion, whether it is increased or reduced by natural exposure to trace cobalt in the soil or water we consume has no effect on metabolic B12. Natural soil and water do not contain sufficient B12 producing organisms to result in this being a primary nutrient source, even in a theoretical 'stone age' level of uncleanliness.

Livestock which are fed grain and leaf forage grown from soils which are deficient in cobalt may not produce sufficient B12 for their own metabolic health and thus most commercially reared livestock will have trace cobalt compounds in the salt lick or mineral amended grain supplements.

These generally do not actually contain B12, as these compounds do not directly pass through the complex digestion of ruminants and would not actually serve the muscle growth targets of the herd, whereas trace cobalt will get those results reliably.

In turn those animals are the nutritional source of B12 for humans, as the two primary bioactive forms, methylcobalamin from cellular cytosol (the internal gel in cells) and adenosylcobalamin from mitochondria.

Vegans can reliably get non-animal sources of B12 from nutritional yeast or from manufactured sources which make the two bioactive forms through bacterial fermentation (typically Pseudomonas denitrificans and Propionibacterium freudenreichii <~ which is the Swiss cheese bubble-causing species) and then stabilized as cyanocobalamin through the addition of potassium cyanide in the presence of nitric acid and heat, which converts back into those two bioactive forms through human digestion.

If we eat meat that was raised to be healthy, then we don't need supplements to get enough B12 to be healthy. If we choose not to eat meat, then sure, supplemental sources will be important to meet metabolic needs. But, dirty roots and cloudy water are not the natural 'wild' source of B12 for humans in any reasonable imagined version of the stone age.