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Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @06:43PM (#27454265)
Any other result would have been surprising. Why is this interesting, beyond just confirming what we were already 99.99% certain we knew?

-- biochemist

Re:Evaluating necessity of Covid-19 vaccination in previousl... by briefcomment on Wednesday June 09, 2021 @08:09PM (#27455093)
Most authorities are downplaying natural immunity, despite evidence like this. The more widely this spreads, the more people will realize it's ok to rely on natural immunity, and to not blanket demonize those who are unvaccinated.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by SkyPuncher on Wednesday June 09, 2021 @09:11PM (#27455583)
> to not blanket demonize those who are unvaccinated.

Well, I'm currently in quarantine from my 4 month old and wife because an acquaintance refused to get vaccinated. "young people don't die from COVID" type mentality.

I attended my brother's bachelor party - of which we all thought everyone was vaccinated. Turns out this person, not only refused to get vaccinated - but had COVID exposure and still decided to attend. He told us the day after being in close contact for 3 days, that he tested positive and had symptoms during our contact with him.

Of the unvaccinated people I know, this mentality is the large majority of them. They refuse to get vaccinated because they refuse to consider how their actions might actually impact someone else.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by briefcomment on Wednesday June 09, 2021 @09:19PM (#27455634)
I'm talking about those who have recovered when I say natural immunity, not all unvaccinated.

Also, presumably, this person would now be as immune as someone who's gotten the vaccine, based on this study.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by heavyset_go on Wednesday June 09, 2021 @10:06PM (#27455945)
> They refuse to get vaccinated because they refuse to consider how their actions might actually impact someone else.

They've considered it, they just don't care. What they actually care more about is the insinuation that they should care at all.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by bobthechef on Wednesday June 09, 2021 @09:52PM (#27455844)
> "young people don't die from COVID" type mentality.

What mentality is this? It is well known that young people are at extremely low risk of dying, even more so than the average person.

> He told us the day after being in close contact for 3 days, that he tested positive and had symptoms during our contact with him.

The problem wasn't that your acquaintance refused the vaccine. The problem is that he didn't stay home. You could say the same thing about the flu. If you have it, don't go to parties. Who goes to a party with a flu? A cold even?

I hardly think this guy is representative. There's also evidence that asymptomatic people don't spread COVID. This would mean that if they don't have symptoms, you won't get it, and if they do and they're like most people, they'll stay home which means no transmission.

> Of the unvaccinated [sic] people I know, this mentality is the large majority of them. They refuse to get vaccinated because they refuse to consider how their actions might actually impact someone else.

This seems unnecessarily hostile. Plenty of people don't want to be vaccinated either because they've had COVID and don't need it (this study isn't the first; Peter McCullough for example has spoken about other studies), they don't want to risk the potential side effects, including long term, of an experimental vaccine that is not technically approved by the FDA, ethical/religious reasons (the use of stem cell lines derived from aborted children during vaccine research, etc), and because the virus is not a serious threat to most people.

It is disturbing how the media is lumping those wary of the COVID vaccine in with antivaxers (~2% of the population; 98% of Americans get all common immunizations), COVID deniers, or "grandma killers". Let's not do that, as the OP recommends.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by cstejerean on Wednesday June 09, 2021 @10:49PM (#27456152)
> There's also evidence that asymptomatic people don't spread COVID. This would mean that if they don't have symptoms, you won't get it, and if they do and they're like most people, they'll stay home which means no transmission.

We wouldn’t be in the middle of a pandemic if this were true.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by jokethrowaway on Thursday June 10, 2021 @06:07AM (#27458952)
It's been a pretty mild pandemic. What has been newsworthy about was the removal of freedom, not the number of dead people.

It's flu-like transmission - which is mostly through droplets. If you're not sneezing in the face of people you don't have high chances of passing it around

Re:Evaluating necessity of Covid-19 vaccination in previousl... by galoisgirl on Thursday June 10, 2021 @06:47AM (#27459184)
It's the 9th pandemic in human history in the number of deaths: https://en.wikipedia.org/wiki/List_of_epidemics#Major_epidem...
Re:Evaluating necessity of Covid-19 vaccination in previousl... by briefcomment on Thursday June 10, 2021 @09:43AM (#27460657)
Looks like it's much lower than 9th population adjusted.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by ping_pong on Thursday June 10, 2021 @03:48AM (#27458061)
There a difference between asymptomatic and presymptomatic.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by tomp on Thursday June 10, 2021 @04:04AM (#27458187)
Parent poster actually meant presymptomatic.

> This would mean that if they don't have symptoms, you won't get it

Re:Evaluating necessity of Covid-19 vaccination in previousl... by rimliu on Thursday June 10, 2021 @03:56AM (#27458120)
Why so? Or are you mixing up asymptomatic with presymptomatic, as many do? It is clear that latter do indeed play a big role in spreading infection, but the science is not so clear on the former. Likely that asymptomatic do not spread it.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by neilwilson on Thursday June 10, 2021 @06:05AM (#27458940)
One of the unfortunate things about SARS2 is that there is reasonable evidence of some asymptomatic spread. Particularly the recent Japanese study[0]

"When taken together, I think these two studies show that people with asymptomatic covid-19 can and do spread the disease, and the best estimate from both studies is that those with symptomatic disease are about three to four times more infectious than those with asymptomatic disease. That is not a huge difference. Even though people with symptoms are a couple of times more infectious than people without symptoms, those without symptoms could still be causing more infections overall."

[0] https://sebastianrushworth.com/2021/06/06/can-asymptomatic-p...

Re:Evaluating necessity of Covid-19 vaccination in previousl... by ping_pong on Thursday June 10, 2021 @03:47AM (#27458052)
Why are you quarantined if you got vaccinated?
Re:Evaluating necessity of Covid-19 vaccination in previousl... by f6v on Thursday June 10, 2021 @04:02AM (#27458164)
Keep in mind that vaccine is not 100% effective.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by ping_pong on Thursday June 10, 2021 @04:46PM (#27465595)
The measles vaccine is less effective than the COVID vaccine, and for mumps is less than 90% effective. Are you going to quarantine yourself over those lowered percentages? Most vaccines are less effective than the COVID vaccine.

To not trust vaccination is to not trust science.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by f6v on Friday June 11, 2021 @04:25AM (#27470655)
Stating the facts is also science.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by SkyPuncher on Thursday June 10, 2021 @04:55PM (#27465696)
Data indicates actual effectiveness as about 91.5%.

However, that's across the population. Factors like extended contact period increase viral load intake, could further decrease the effectiveness. Since my 4 month old can't get vaccinated against COVID yet, we decided it wasn't worth taking the risk.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by ping_pong on Thursday June 10, 2021 @11:52PM (#27469105)
Infants almost have a 0% chance of encountering any issues with COVID. 8 out of 100,000 children need to be hospitalized. You're talking about a 0.08% chance of hospitalization and for infants it's actually even lower.

Most vaccines have an efficacy lower than the COVID vaccines. Basically you are feeding off of your own fear, and you don't trust science. That's your right, but don't blame anyone for your self-imposed quarantine but yourself at this point.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by nicioan on Thursday June 10, 2021 @05:18AM (#27458634)
100% this. It's not only about oneself. For young and healthy people, vaccination is primarily for helping and protecting others.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by rectang on Wednesday June 09, 2021 @08:32PM (#27455286)
The unvaccinated are still vectors for the infection of those who cannot be vaccinated, such as the immunocompromised. I personally don't think in terms of "blanked demonizing" people, but neither am I going to blanket-absolve all the unvaccinated — especially willful anti-vaxxers.

Regardless, this study is good news — because it means that every person who is infected and then recovers contributes towards herd immunity, regardless of their outlook on vaccines.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by briefcomment on Wednesday June 09, 2021 @08:57PM (#27455482)
I'm talking about those who have recovered when I say natural immunity, not all unvaccinated.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by jdminhbg on Thursday June 10, 2021 @12:05AM (#27456547)
> The unvaccinated are still vectors for the infection of those who cannot be vaccinated, such as the immunocompromised

Is it actually the case that immunocompromised people cannot be vaccinated? The ones that I know have been; as far as I know, the mRNA vaccines by virtue of not being based on live virus are not dangerous to those with weakened immune systems.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by jacobolus on Thursday June 10, 2021 @01:27AM (#27457009)
Immunocompromised people can safely get the vaccine, but it might not work, leaving them still vulnerable to the virus.

In recent studies something like half of organ transplant recipients did not produce antibodies after being vaccinated, and there have been a few cases where a group of vaccinated transplant recipients caught Covid (e.g. from a vaccinated nurse who had an asymptomatic infection) and had severe symptoms including some deaths.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by ticviking on Thursday June 10, 2021 @10:35AM (#27461249)
Can you provide a link to those cases?
Re:Evaluating necessity of Covid-19 vaccination in previousl... by f6v on Thursday June 10, 2021 @04:04AM (#27458185)
There might also be not enough data on how vaccine affects people with rare health conditions.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by Sleepytime on Thursday June 10, 2021 @03:23AM (#27457880)
The vaccinated are still vectors for the infection of those who cannot be vaccinated.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by paedubucher on Thursday June 10, 2021 @04:11AM (#27458230)
If you are immunocompromised, you're not only vulnerable to COVID-19, but to a plethora of other viruses going around all the time.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by cuchoi on Wednesday June 09, 2021 @08:37PM (#27455335)
My wife and I got COVID twice 9 months apart last year. The second time my wife ended up in the hospital.

We both got vaccinated as soon as we could.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by colordrops on Wednesday June 09, 2021 @11:27PM (#27456350)
Re-infection is very rare, so the chance that it happened to two people in the same household is extremely rare. Are you certain you were infected with covid both times?
Re:Evaluating necessity of Covid-19 vaccination in previousl... by cuchoi on Thursday June 10, 2021 @11:16AM (#27461680)
Not certain, but the second time we had a positive PCR test to confirm. The first time, there were no tests in NYC but close contacts had it and we had the same exact symptoms (which are not similar no any other flu/disease we have had).
Re:Evaluating necessity of Covid-19 vaccination in previousl... by galoisgirl on Thursday June 10, 2021 @06:51AM (#27459203)
People in the same household have high chances of infecting each other.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by marton78 on Thursday June 10, 2021 @07:10AM (#27459320)
Please read that comment again, it's about RE-infection
Re:Evaluating necessity of Covid-19 vaccination in previousl... by galoisgirl on Thursday June 10, 2021 @07:44AM (#27459531)
I know it is, my point is that two spouses getting re-infected isn't two independent things.

It's not like bringing your bomb onto a plane decreases the odds of an attack, because what are the odds of two bombs.

The devil is in the details here. If natural immunity wears off after 6-9 months (as some studies suggest), and one spouse got infected again after that period, then the odds of the other one of getting re-infected too are pretty high.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by gretch on Wednesday June 09, 2021 @08:52PM (#27455444)
Wow really? Do you have positive test results that document the sequence of events?

If so you should probably email these researchers or something. Bet they would be interested

Re:Evaluating necessity of Covid-19 vaccination in previousl... by pama on Wednesday June 09, 2021 @09:39PM (#27455762)
There is already a decent understanding of documented reinfections. The first such cases came out a year ago, e.g.: https://en.yna.co.kr/view/AEN20200406006700320 , or https://www.jpost.com/health-science/israeli-doctor-reinfect... By the end of last summer there were clear documented cases with secondary infection from a different viral strain than the original one, e.g: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3681489 The original publication (and the reply that I cite that raises some concerns, but leaves the main argument in place) estimated that the protection from a past infection is about 83%, so significantly smaller than that from the 2-dose mRNA vaccines. https://www.bmj.com/content/372/bmj.n124/rr-0
Re:Evaluating necessity of Covid-19 vaccination in previousl... by jokethrowaway on Thursday June 10, 2021 @06:12AM (#27458979)
While I agree reinfections are likely to exist in small numbers, the tests we're using are often not great so it's hard to say whether those were covid or something else.

This year I've been heavily sick several times (and the flu almost never caused me all this pain before in my life) and it was never covid.

If one of the test returned a false positive I would have been convinced it was covid. If I actually got covid again I would have believed I was one of the rare reinfections.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by cuchoi on Thursday June 10, 2021 @11:21AM (#27461754)
PCR tests are more likely to give you a false negative than a false positive.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by cuchoi on Thursday June 10, 2021 @11:17AM (#27461704)
The second time we had a positive PCR test to confirm. The first time, there were no tests in NYC but people I worked with had it confirmed and we had the same exact symptoms (which are not similar no any other flu/disease we have had).
Re:Evaluating necessity of Covid-19 vaccination in previousl... by thehappypm on Thursday June 10, 2021 @04:33PM (#27465420)
You really shouldn't be saying this on public forums without proof. You have no proof that the first infection wasn't the flu or a bad cold. The odds of reinfection are very small, and the odds of both of you getting reinfected is vanishingly so. Without proof this is potentially fear mongering.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by barbazoo on Thursday June 10, 2021 @12:03AM (#27456536)
I can imagine it being downplayed out of fear that it could slow down the vaccination program by pushing people over the edge that were hesitant to get vaccinated and possibly questioning covid-19 in the first place.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by briefcomment on Thursday June 10, 2021 @12:21AM (#27456616)
It's fine if those previously infected don't get the vaccine. I don't see why information on how natural immunity is effective would make people who haven't gotten Covid even less likely to get the vaccine.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by jacobolus on Thursday June 10, 2021 @01:38AM (#27457111)
There are many people who are convinced their respiratory infection earlier in the pandemic was Covid despite never having been tested. While some of those may plausibly have been Covid, many were surely flu or some other disease.

It would be a shame if such people avoided the vaccine under a disinformation-driven impression that the vaccines are risky, and ended up catching/spreading Covid later on.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by barbazoo on Thursday June 10, 2021 @12:48AM (#27456758)
I can only imagine it's because it might convince people that don't take Covid-19 seriously to not get the vaccine because even if they didn't get it, they'd be immune once infected going forward, missing the point about hospitalization, protecting the vulnerable, etc.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by hn_throwaway_99 on Wednesday June 09, 2021 @10:23PM (#27456025)
> Most authorities are downplaying natural immunity, despite evidence like this.

OK, I think I can agree with this, I've seen lots of "getting the vaccine provides much better immunity than getting Covid"-type statements that seemed more like conjecture.

> The more widely this spreads, the more people will realize it's ok to rely on natural immunity, and to not blanket demonize those who are unvaccinated.

Is this a serious statement? The problem isn't that natural immunity doesn't keep make you immune, the problem is that "acquiring natural immunity" often results in death, especially for vulnerable populations.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by JeremyNT on Wednesday June 09, 2021 @10:51PM (#27456166)
> > The more widely this spreads, the more people will realize it's ok to rely on natural immunity, and to not blanket demonize those who are unvaccinated.

> Is this a serious statement? The problem isn't that natural immunity doesn't keep make you immune, the problem is that "acquiring natural immunity" often results in death, especially for vulnerable populations.

It's a real policy question: how much to worry about vaccinating people who already had COVID. The confusion (or propaganda?) downplaying natural immunity means that many people would needlessly get the vaccine while already possessing immunity from prior infection.

In the US, this no longer matters, as we already have more vaccine supply than we have people willing to receive it. Elsewhere, though, where supplies remain scarce, we absolutely should be focusing efforts around vaccinating people who have not yet gotten the disease.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by briefcomment on Wednesday June 09, 2021 @10:52PM (#27456169)
> the problem is that "acquiring natural immunity" often results in death, especially for vulnerable populations

You're reading beyond what I'm saying. My point is that there is no need to push those who have already gotten Covid to also get the vaccine. I'm not saying anything about getting sick as an alternative to getting the vaccine.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by hn_throwaway_99 on Wednesday June 09, 2021 @11:17PM (#27456311)
Thanks, and apologies, I misunderstood your comment.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by rayiner on Wednesday June 09, 2021 @10:47PM (#27456140)
It rarely results in death. Even men 65-75 have a only a 3% chance of dying if they get covid. To put that into perspective, according to the mortality tables, those people have a 1.5-3.5% chance of dying in a given year even under normal circumstances.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by tptacek on Thursday June 10, 2021 @01:58AM (#27457250)
Polio has a death rate in the mid single digits, too.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by rayiner on Thursday June 10, 2021 @05:55AM (#27458892)
For children and middle aged adults as well, not just people over 65. That and the permanent deformity and paralysis are a big difference.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by OJFord on Wednesday June 09, 2021 @06:55PM (#27454409)
Because it's not public health policy anywhere that I'm aware of? But vaccine rollout would be way quicker, and 'positive test or vaccinated' proportion of populations would be way higher, and that would influence discussion of other aspects, like 'herd immunity' for example.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by stormbrew on Wednesday June 09, 2021 @07:25PM (#27454711)
I'm incredibly skeptical that it would do much at all to hasten rollout, at least in the US and other countries in a similar place. There are more than enough vaccines to go around at this point[1], and adding any kind of question mark to "should I get it?" just creates unnecessary complexity.

Just get it in everyone's arms as fast as possible, all this dicking around with rules around who can or should get it now that it's plentiful is just slowing everything down.

[1] to the point that 'we' should be doing a lot more to get our excess to countries that are still struggling.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by OJFord on Thursday June 10, 2021 @03:38AM (#27457985)
Well I'm not really necessarily saying it should change now, but I was responding to 'this has always been obvious, why interesting' - you'd think policy would've been different from the start if it were so obvious.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by handmodel on Wednesday June 09, 2021 @07:17PM (#27454629)
My one anti-vax friend (who I make fun of constantly for not getting it) is constantly bombarded with people telling him that his previous infection doesn't give him any immunity. I already knew that was false - and I think he knew that too. It probably fed into his (motivated) reasoning to hold out this long if people are telling him so much information they know to be untrue.

Still, I don't see how public health would benefit from not recommending shots to everyone as there is no downside.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by jokethrowaway on Thursday June 10, 2021 @06:32AM (#27459093)
The only reason I got the vaccine is because of the chance idiotic unscientific governments won't bother me with tests I need to pay for when travelling.

I'm not a "anti-vaxxer" "conspiracy theorist" "racist" "sexist" "nazi" but the risk is just too low for me to care. If you think covid can affect you, take the vaccine and don't bother me. I self isolated weeks before the government told me so because we didn't know what the risk involved was. By the time the government approved a 2 weeks lockdown which turned into 1 year and a half, it was already evident the risks were minimal. This is all a political play and I shudder when I think about what's coming next. Shall we do a climate change lockdown next? Or shall we try some more covid variants first?

I also don't think vaccines are likely to be dangerous (minus the platelets / blood clots issue - hopefully no long term issues pop up in 10 years).

Also, the downside is that everyone is paying for these shots, they're not free and they come out of the taxes the government steals from me every month - and they accomplish very little. Same as the flu shots.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by krrrh on Wednesday June 09, 2021 @11:00PM (#27456215)
We don’t know that there is no downside which is why these vaccines were approved via Emergency Use Authorization. At the very least I and several people I know were absolutely flattened by the vaccines for a day or two. One guy I know had very low blood sugar for weeks afterwards and needed medical intervention.

The vaccines are important in establishing herd immunity, but I don’t understand the desire to jab people who already have established immunity.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by IgorPartola on Thursday June 10, 2021 @12:24AM (#27456627)
Feeling symptoms of COVID after receiving the vaccine is a normal and expected result that makes common sense: your immune system is doing its job. The only possible long term side effect here is partial or total immunity from COVID. On the other hand you don’t know the long term effects of COVID either, but I would bet dollars to donuts that they are worse than from the vaccine, based on what we know as of today.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by krrrh on Thursday June 10, 2021 @12:51AM (#27456773)
> The only possible long term side effect here is partial or total immunity from COVID.

You don’t need to convince me to get vaccinated, but this is a profoundly unscientific statement. The mRNA vaccines are a brand new technology that would not have been approved without several years of human trials if there was not a pandemic justifying rushing through the normal process.

So far so good, but the immune system is a complex system and we can’t rule out some unexpected side effects for some people some of the time.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by rolph on Thursday June 10, 2021 @12:59AM (#27456826)
one of the other long term effects of covid transmission, is the opportunities given for variation and selection according to viral efficiency, in effect each infection is a crap shoot toward generation of recombinants, or molecular variants
Re:Evaluating necessity of Covid-19 vaccination in previousl... by OJFord on Wednesday June 09, 2021 @07:27PM (#27454725)
> I don't see how public health would benefit from not recommending shots to everyone as there is no downside.

You'd get all the never infected people vaccinated sooner; so 'everyone' (except anti-vax not infected prior to effective 'herd immunity') would be immune sooner.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @07:36PM (#27454832)
Yeah, in theory that would be the obvious advantage.

In practice, don't underestimate how much more inefficient or troublesome a seemingly simple additional rule or exception might be to administer... :P

Re:Evaluating necessity of Covid-19 vaccination in previousl... by handmodel on Wednesday June 09, 2021 @07:56PM (#27454998)
That's my thing. Plenty of people who know they almost certainly had Covid weren't tested, some were tested with tests that were experimental, etc.

And while trying to predict second-order behavior effects is tricky either way it is pretty clear that saying "don't get the vaccine if you already had Covid" would scare some people away.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by Sebb767 on Wednesday June 09, 2021 @08:30PM (#27455274)
> Plenty of people who know they almost certainly had Covid weren't tested

I had quite the opposite experience ; plenty of people told me they had (mild) flu symptoms - a lot of TMI, to be honest - and assumed they had had COVID already. It later turned out, with no exception, that they absolutely did not.

Scaring those people away would probably hurt a lot, at least in my anecdotal experience.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by landemva on Wednesday June 09, 2021 @09:59PM (#27455891)
"Plenty of people who know they almost certainly had Covid weren't tested..."

Do you mean tested for antibodies with finger prick blood test, or PCR random number generator (see elon musk wild PCR results).

I was sick, had test that showed antibodies, and a confirmation letter from my Dr.

Since the EUA to rush out the vaccines does not include those who had it and recovered, it needs more testing and study before it is approved for those who have antibodies. The jab is not risk-free.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by manwe150 on Thursday June 10, 2021 @12:37AM (#27456708)
That was true when the EUA was issued, but by now, we have vaccinated major segments of the population without seeing issues (e.g. hospitalizations are decreasing even as the rate of exposed population is much higher).

I was in a similar position as you: possible early COVID exposure (though no symptoms), several positive antibody tests, but absolutely zero side effects from either Pfizer shot. Annoyed not a few people though by my lack of any reaction to the shots, so that was kinda fun.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @08:07PM (#27455081)
Bingo.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by jancsika on Wednesday June 09, 2021 @11:50PM (#27456463)
This guy secures.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by briefcomment on Wednesday June 09, 2021 @08:13PM (#27455134)
It's certainly arguable that there is downside for some people. Some vaccine side effects are worse for some people who have already been infected. [1]

[1] https://www.kfyrtv.com/2021/03/15/health-experts-say-those-p...

Re:Evaluating necessity of Covid-19 vaccination in previousl... by lukeschlather on Wednesday June 09, 2021 @09:07PM (#27455553)
How do you know your anti-vax friend was actually infected? I think a very real risk is that people decide they don't need the vaccine based on false-positive tests or otherwise mis-diagnosed illness.

This study appears to be based on following up with a single hospital's own database of people who tested positive. But I imagine you would get different results if you just found a bunch of people and asked them to self-report their prior infection status before enrolling them in the study.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by handmodel on Wednesday June 09, 2021 @09:42PM (#27455778)
He was tested twice and came back positive both times - many people in his workplace had it. He 100% had it.

Agree on the self-reporting, but I guess my larger point is he already doesn't want to get the vax and people telling him that his natural immunity is not sufficient makes him even more distrustful since he does know enough about science/statistics to see that natural immunity is about equal with a vaccine as far as we can tell.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by AndrewBissell on Wednesday June 09, 2021 @07:34PM (#27454810)
> Still, I don't see how public health would benefit from not recommending shots to everyone as there is no downside

The VAERS data suggests there are numerous groups at very low risk from Covid for which this may not be the case.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @07:47PM (#27454930)
This is a dubious claim, and is a frequent anti-vaxx/vaccine-hesitancy talking point.

VAERS data needs to be interpreted with special care. It's not equivalent to a safety study with a proper experimental design. It has a whole lot of legal and administrative context to account for.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by unanswered on Wednesday June 09, 2021 @07:56PM (#27454999)
And until the studies happen there is no danger? The studies create the danger? Or may we behave like rational individuals and realize that "zero danger" is a political talking point which is fully debunked by the VAERS data?
Re:Evaluating necessity of Covid-19 vaccination in previousl... by ceejayoz on Wednesday June 09, 2021 @08:02PM (#27455042)
VAERS is user-generated content. I can go in there and file a report that I grew a third arm after vaccination and it'll go in.

Dying or having an adverse event after vaccination also isn't the same as dying from vaccination; even the genuine VAERS reports don't permit teasing this wrinkle out on their own.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by AndrewBissell on Wednesday June 09, 2021 @08:25PM (#27455235)
> I can go in there and file a report that I grew a third arm after vaccination and it'll go in.

And you'd be committing a felony. I see this idea tossed around all the time that tons of the reports coming in are fake, but so far have seen scant evidence that that's the case.

> Dying or having an adverse event after vaccination also isn't the same as dying from vaccination; even the genuine VAERS reports don't permit teasing this wrinkle out on their own.

Okay, but then why are so many more people reporting dying after Covid-19 vaccination than have reported dying after flu shots which have been administered to millions of people for decades?

Re:Evaluating necessity of Covid-19 vaccination in previousl... by ceejayoz on Wednesday June 09, 2021 @08:29PM (#27455259)
What felony?

https://www.politifact.com/factchecks/2017/may/11/bill-zedle...

> In a July 2005 web post, Dr. James R. Laidler wrote: "The chief problem with the VAERS data is that reports can be entered by anyone and are not routinely verified. To demonstrate this, a few years ago I entered a report that an influenza vaccine had turned me into The Hulk. The report was accepted and entered into the database.

> "Because the reported adverse event was so… unusual," Laidler wrote, "a representative of VAERS contacted me. After a discussion of the VAERS database and its limitations, they asked for my permission to delete the record, which I granted. If I had not agreed, the record would be there still, showing that any claim can become part of the database, no matter how outrageous or improbable."

As for your question about the numbers:

https://www.politifact.com/article/2021/may/03/vaers-governm...

> Moss explained one way VAERS can amplify fears about the COVID-19 vaccine in particular. Most vaccinations are given to a small segment of the population: young, healthy children, who are generally less likely to have health problems afterward. But the COVID-19 vaccine is given to a much larger group — all Americans 16 and older are eligible now. And the earliest recipients included a large number of elderly patients and adults with preexisting health problems.

https://www.reuters.com/article/uk-factcheck-vaers/fact-chec...

> “To date, VAERS has not detected patterns in cause of death that would indicate a safety problem with COVID-19 vaccines.”

Re:Evaluating necessity of Covid-19 vaccination in previousl... by AndrewBissell on Thursday June 10, 2021 @03:35AM (#27457958)
Do you look at anything other than factchecks? Taken right from the VAERS website (in bold font, no less): "Knowingly filing a false VAERS report is a violation of Federal law (18 U.S. Code § 1001) punishable by fine and imprisonment." A single case of a doctor submitting a goofy report in 2005 (and even having the CDC follow up with him!) doesn't establish a widespread pattern. Has even a single such incident been reported with the Covid VAERS submissions? I have to imagine the media would be keen to trumpet it, given their evident interest in putting out the word that there's "nothing to see here" in the VAERS numbers.

> Moss explained one way VAERS can amplify fears about the COVID-19 vaccine in particular. Most vaccinations are given to a small segment of the population: young, healthy children, who are generally less likely to have health problems afterward. But the COVID-19 vaccine is given to a much larger group — all Americans 16 and older are eligible now. And the earliest recipients included a large number of elderly patients and adults with preexisting health problems.

This is trivially accounted for by comparing Covid and influenza vaccines. If I limit to ages 18-59 I get ~73,000 total adverse events for influenza vaccines across their entire history, and 173,000 adverse events for Covid vaccines since they started to be administered at the beginning of the year.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Thursday June 10, 2021 @12:49PM (#27462773)
It really is not "trivially accounted for" in this manner. The flu is an annual thing that most people are coping well with mentally. Can't quite say the same about the latest pandemic, and people's attitudes and beliefs are going to significantly colour the amount and nature of the self-reporting system.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by AndrewBissell on Thursday June 10, 2021 @01:24PM (#27463163)
Those are separate concerns from the age/demographic ones I was addressing. I could see what you raise driving some difference in the rates of reporting to VAERS. I could not see it driving a difference of, say, zero "Death + Life Threatening" reports for influenza vaccines in 2020 versus 2,857 "Death + Life Threatening" reports for Covid vaccines in 2021 for the 18-59 age group.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @08:05PM (#27455062)
You need to apply some Bayesian thinking. No reasonable person (expert or not) believes in such a thing as zero danger.

- The vast majority of new drugs that undergo safety trials are found to have serious side effects.

- The near totality of new vaccines that undergo safety trials are found to have a formidably beneficial risk profile.

Don't make the mistake of applying the same risk heuristic in your mind for both things. Risk assessments in science have absolutely nothing to do with politics.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @07:04PM (#27454498)
I don't think this is incompatible with public health policy even if public health policy treats previously-infected people the same way as never-infected people.

Owing to the dramatic risk asymmetry between vaccine and disease, it's probably better to implement a policy that optimizes more for expediency, simplicity (fewer rules and fewer exceptions) and, in this case, minimizing the number of false assumptions made about the status of individuals. ie.: in the context of vaccination it's sometimes better to not assume that everyone who claims to have been previously infected was actually infected, even if we have lab data to back up this assumption.

I'm not saying current policies all make perfect sense or anything, but it doesn't particularly surprise me that everyone is being accounted for in the same way WRT the vaccine.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by ufo on Wednesday June 09, 2021 @11:31PM (#27456371)
I wish. Here in Brazil it's effectively the official policy. Multiple times our president has shown that he'd rather give us chloroquine instead of vaccines.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by BelenusMordred on Wednesday June 09, 2021 @09:01PM (#27455512)
Many EU countries will take either proof of prior infection, a vaccine cert, or PCR test for international arrivals. It's very much public policy for some.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by tootie on Wednesday June 09, 2021 @07:46PM (#27454926)
There were stories of reinfection happening. Also variants. Also, every covid study of every kind is getting an enormous amount of attention and resources
Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @07:49PM (#27454941)
Given a large enough sample size, reinfections are pretty much guaranteed to happen. These are not incompatible with each other.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by StavrosK on Wednesday June 09, 2021 @06:48PM (#27454331)
It's just nice for us laymen to have more confirmation.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by cuchoi on Wednesday June 09, 2021 @08:40PM (#27455356)
What made you 99.99% before reading this? I have seen plenty of experts saying that they don't know how long immunity will last.

Anecdotal data: my wife and I got COVID twice 9 months apart last year. The second time my wife ended up in the hospital.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by shitgoose on Wednesday June 09, 2021 @09:53PM (#27455855)
Aren't pcr tests notoriously unreliable? Maybe you didn't have it first time?
Re:Evaluating necessity of Covid-19 vaccination in previousl... by cuchoi on Thursday June 10, 2021 @11:14AM (#27461667)
Had the same symptoms both times (dry cough for 5 weeks, using inhalator, loss of smell, etc.). It could have been a very a flu very similar to COVID at the exact time NYC was locking down due to COVID?
Re:Evaluating necessity of Covid-19 vaccination in previousl... by rriepe on Wednesday June 09, 2021 @08:29PM (#27455263)
There's a bunch of hidden social rules around commenting on immunity because the last big pandemic was HIV.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by bregma on Thursday June 10, 2021 @07:24AM (#27459408)
If medicine depended on what we already know to be true then Big Leech would be in control of healthcare.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by psychlops on Wednesday June 09, 2021 @08:02PM (#27455046)
It's consistent with the past years saturated reporting of the obvious about infectious diseases.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by void_mint on Wednesday June 09, 2021 @08:07PM (#27455084)
Further evidence is further evidence, no? You have to measure and assess to get results...
Re:Evaluating necessity of Covid-19 vaccination in previousl... by rickspencer3 on Wednesday June 09, 2021 @08:58PM (#27455487)
All scientific findings are obvious or wrong.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by symlinkk on Wednesday June 09, 2021 @06:54PM (#27454393)
Because openly stating this obvious fact would get you downvoted on here a few months ago.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by adventured on Wednesday June 09, 2021 @08:49PM (#27455422)
> Because openly stating this obvious fact would get you downvoted on here a few months ago.

Attempting to discuss it here will still commonly get you downvoted. HN is not a particularly rational forum. People make the mistake of thinking it is because a lot of engineers hang out here. Engineers are not especially rational, that's a common myth derived from failing to understand the way people mentally compartmentalize; how they can frequently be rational about one subject and irrational about another.

Try this one for example: the numbers they've been reporting about Covid infections the past year are not the actual infection numbers, not even remotely close. Yet they're held up everywhere as being representative of how many infections there have been.

This is still the biggest comedy going about the pandemic. It's hilarious how batshit crazy people can be.

If the US were a sane nation, the people that have been trying to represent the supposedly official infection count as being fully representative of the number of infections that have occurred - those people would be publicly mocked and shamed for being anti-science, the equivalent of flat-earthers. Instead, the flat-earthers dominate the media and national discussion. That's why the lab-leak theory was buried under so much censorship and for so long, those same people have been holding that conversation back very aggressively.

Most people know on some level that the held-up official infection tally is not representative of the real number of infections. And yet the mainstream media, without exception, pretends those are the legitimate infection numbers. Any attempt to discuss how many infections have really occurred, will be shouted down. The shrieking emotionalism that pours out when you open this can of worms, is endlessly fascinating to me.

If you say: how many people in the US have had Covid, they'll point at the magic official number, which is not correct.

If we wanted to have a serious discussion nationally about herd immunity (for example), one of the most important steps is one they intentionally refuse to take: let's try to get a more serious estimate on how many people nationally have actually had Covid.

They won't have that conversation and the media goes out of its way to avoid it (and has done so for a year now). Why? Pick your poison on the why answer. Political psychopaths lusting for control, looking to prolong their ability to take advantage of a disaster (the 'ol never waste a good crisis mentality). Wildly irrational anti-science types in power that pretend they represent science, which is the wing that Fauci belongs to. Maybe a combination. Maybe it's just the fear that if the masses of people think we're anywhere near herd immunity, the vaccination rates will plunge even faster, so some people want to maintain the false illusion (on the actual infection counts) as long as possible.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by reducesuffering on Thursday June 10, 2021 @01:05AM (#27456861)
Ok, essentially you’re saying the real number of cases is higher than the official numbers reported, because the official numbers only report ones confirmed by tests, and there are many people who got Covid and were never tested.

I think most on HN would agree with your assessment that the real number of cases are somewhat higher than the official count, although I haven’t seen any evidence indicating exactly how much higher or lower. The Dakota states did seem to taper off cases immensely before the vaccines were distributed, indicating a possible early herd immunity.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by amanaplanacanal on Thursday June 10, 2021 @12:00AM (#27456521)
I’d love to see real numbers of how many people have been infected, but I have no idea how you would get them. Do you have any suggestions?
Re:Evaluating necessity of Covid-19 vaccination in previousl... by nradov on Thursday June 10, 2021 @12:41AM (#27456725)
The most accurate approach would be to do repeated blood tests of a large nationwide study population looking at both antibodies and memory T cells. The CDC really should have been doing that nationwide for the past year.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by manwe150 on Thursday June 10, 2021 @01:12AM (#27456892)
The Red Cross Blood Donation centers perhaps come closest to doing this. From their emails, it sounded like they never saw widespread active antibodies (until a few months ago).
Re:Evaluating necessity of Covid-19 vaccination in previousl... by nradov on Thursday June 10, 2021 @02:07AM (#27457341)
The Red Cross only did antibody testing which has a significant false negative rate, especially on patients who recovered from mild infections many months ago. That's why getting accurate numbers would require repeatedly testing the same subjects at regular intervals, and also assaying their memory T cells.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by ping_pong on Thursday June 10, 2021 @03:52AM (#27458090)
How can you do that with over 50% of the population fully vaccinated?
Re:Evaluating necessity of Covid-19 vaccination in previousl... by nradov on Thursday June 10, 2021 @08:31AM (#27459868)
The point is that they should have been doing that since tests were first available, before anyone was vaccinated. Even now it would still be a useful study in the unvaccinated population.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by kbelder on Thursday June 10, 2021 @03:18PM (#27464476)
My favorite was when they uncritically accepted China's claim of reducing infections to nearly zero within a span of a few weeks. (5,000 per day to 50 per day in four weeks).

That's so unlikely it's laughable, but it's widely reported and accepted.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @08:56PM (#27455473)
You're fixating on a very strange point.

No scientist ever believes any measurement to be perfectly accurate, and different types of random error, systematic errors, and statistical biases always need to be accounted for.

And they are.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by AndrewBissell on Wednesday June 09, 2021 @07:08PM (#27454530)
My brother-in-law who recovered from Covid was told that it actually put him at higher risk from a subsequent infection, and therefore taking the vaccine was even more important than if he had never had it. Every time someone with any prominence says, "I'm not getting vaccinated because I was already infected" there's a whole "well ackshually!" army that descends to insist that yes it's still SUPER IMPORTANT to get the shot. So I think your 99.99% number is overstating certainly the general public's level of knowledge on this question.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @07:18PM (#27454638)
The person who told your brother this is either a non-expert, or some expert who for some reason is giving medical advice which is incompatible with the scientific consensus (this would really boggle my mind).

PS.: my 99.99% refers to the state of human knowledge and is more about what experts in the field know than what the general public knows.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by rajin444 on Wednesday June 09, 2021 @07:27PM (#27454726)
> some expert who for some reason is giving medical advice which is incompatible with the scientific consensus

Does that really boggle your mind? We're all human. I don't think there's a relationship between being an expert and being honest.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @07:38PM (#27454853)
I know there's always going to be PhDs who believe the earth is flat, because humans are like that... But it's just so hard to relate to super intelligent people believing crazy things. It really does boggle my mind!
Re:Evaluating necessity of Covid-19 vaccination in previousl... by unanswered on Wednesday June 09, 2021 @07:57PM (#27455006)
You understand that people may not always say the same thing they believe to be true, right? People lie.
Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @08:51PM (#27455431)
Of course I realize this, but unless you're suggesting that most PhDs lie most of the time, I'm not sure how this is relevant.

Just a reminder that these are actually good heuristics to live by, in life in general:

- https://en.wikipedia.org/wiki/Wikipedia:Assume_good_faith

- https://en.wikipedia.org/wiki/Wikipedia:Assume_the_assumptio...

Re:Evaluating necessity of Covid-19 vaccination in previousl... by AndrewBissell on Wednesday June 09, 2021 @07:26PM (#27454721)
> some expert who for some reason is giving medical advice which is incompatible with the scientific consensus (this would really boggle my mind)

Doesn't really seem that mind boggling to me. The clear public health impetus at this point is simply to get shots in as many arms as possible. We've already had Fauci openly admit that he gave guidance against masking and low-balled herd immunity threshold estimates because he presumed it would not lead to the behavior he desired from the public at the time. It's not hard to imagine that mentality has made its way into the rank-and-file somewhat.

Re:Evaluating necessity of Covid-19 vaccination in previousl... by epgui on Wednesday June 09, 2021 @07:43PM (#27454893)
I think what I was referring to, and the examples you're giving, are very different. The early advice against masks were the best advice public health could give, with the information that was available (even among experts) at the time. I would give the same advice as Fauci at the time. There are a bunch of factors to consider: behavioural (people having a false sense of security and taking greater exposure risks, or people not using masks properly and actually increasing their risk), medical (at the time, the benefits of non-N95 masks were not as clear as they are now) and system-level (supply chain issues were real, many countries had a really hard time getting procurement of basic PPE for hospitals... and you want to make sure you prioritize hospital workers over the general population)