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Re:Covid-19: Do many people have pre-existing immunity? by choeger on Thursday September 17, 2020 @11:09AM (#24505552)
Right now, this seems to be the best explanation for a lot of the unexpected observations we made so far:

* few children seem to be sick from that virus * geographical disparity in Europe (compare northern Germany vs. northern Italy), even considering population density * the high number of reportedly asymptomatic cases * uneven distribution of infectiousness ("superspreaders")

My pet theory so far is that one or more very similar viruses have been in circulation for a while and that "asymptomatic" carriers of COVID-19 are in fact at least partially immune due to exposure to these similar viruses.

Note that this also means that COVID-19 is much scarier than it looks. Because if you are not among those with prior immunity, you are much more likely to suffer from the bad effects of that virus.

Re:Covid-19: Do many people have pre-existing immunity? by gnusty_gnurc on Thursday September 17, 2020 @11:19AM (#24505697)
My pet theory is that chronic disease like obesity, combined with pre-existing immunity, and possibly some correlation to vitamin-d deficiency explains most of how this has played out.

Factor in a glut of people who're living into advanced age, due to the progress of medical technology, so naturally in a precarious place against any infection. And of course, mismanagement of those people in nursing homes means guaranteed disaster.

So really, I think it's much less dangerous than we've let on, but deadly to certain demographics, that happen to be larger in the West (obese, diabetic, etc.).

Re:Covid-19: Do many people have pre-existing immunity? by nradov on Thursday September 17, 2020 @11:51AM (#24506128)
Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @11:25AM (#24505784)
This doesn't pan out when children have developed severe inflammatory responses, young adults have died, and not all people with comorbidities have had severe reactions. You can't just say it's fat and/or old people who are having severe symptoms or dying.
Re:Covid-19: Do many people have pre-existing immunity? by jaywalk on Thursday September 17, 2020 @11:37AM (#24505941)
We have to look at the bigger statistics. Some young children die of many things that the vast majority of them easily survive, but that doesn't mean we need to lock down every flu season.
Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @11:51AM (#24506134)
Flu is harder to transmit and there is vaccine infrastructure available every year, despite that, it can still be very severe. Let's add a coronavirus with potentially greater severity than a flu, which has no vaccine, and has easier transmission, with a severe flu season this year and just watch the bodies pile up.
Re:Covid-19: Do many people have pre-existing immunity? by just-juan-post on Thursday September 17, 2020 @12:09PM (#24506401)
> with a severe flu season this year and just watch the bodies pile up.

There is no evidence of this and you are continually creating worst-case scenarios.

Please stop.

Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @01:20PM (#24507317)
Do you know that this year will not be a difficult flu season? Do you know the ramifications of combined flu and COVID-19 infection?

If the flu season is severe, then it could be quite catastrophic when combined with COVID-19. We should definitely be preparing for worst-case scenarios, and not downplaying potential severity because it's inconvenient.

Re:Covid-19: Do many people have pre-existing immunity? by Gwypaas on Thursday September 17, 2020 @01:30PM (#24507437)
Influenza and Noro/Calicivirus (Winter vomiting disease) stats for Sweden this year. Social distancing and increased hygiene measures implemented mid March, about week 11, killed them off much earlier than usual.

Influenza: https://www.folkhalsomyndigheten.se/globalassets/statistik-u...

Calicivirus (Vinter vomiting disease): https://www.folkhalsomyndigheten.se/contentassets/0ad710ef37...

Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @01:42PM (#24507599)
Technically that was "last flu season", not the upcoming flu season, and it was relatively mild. It is hard to predict if 2020-2021 will be similar, or 2017 levels, or 2009 levels. At minimum it will add more strain to medical services.
Re:Covid-19: Do many people have pre-existing immunity? by Gwypaas on Thursday September 17, 2020 @02:07PM (#24507935)
It shows that "okay" measures against COVID are strong enough to push the R_eff value for those viruses well below 1, unless something extraordinary happens. I.e. no extra strain for medical services.

As said, this hinges on social distancing and hygiene measures being kept enforced. If you open a country fully again and get two simultaneous peaks then you are in for a bad time.

Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @02:29PM (#24508254)
I think we're on the same page here. My catastrophic scenario involved no mitigation steps and removal of lockdown. The goal was to dissuade people from thinking since things are "fine/better" right now, lockdown/mitigation is not needed anymore. We still need to get through this winter, and on to a vaccine.
Re:Covid-19: Do many people have pre-existing immunity? by mikem170 on Thursday September 17, 2020 @02:02PM (#24507872)
"The southern hemisphere skipped flu season in 2020, Efforts to stop covid-19 have had at least one welcome side-effect"

https://www.economist.com/graphic-detail/2020/09/12/the-sout...

Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @02:15PM (#24508066)
My point to jaywalk was that combined COVID-19 + severe flu w/o mitigations like a lockdown, could be catastrophic. Their post was anti-lockdown comparing COVID-19 to flu.

I am not surprised that measures to avoid COVID-19 also reduces the spread of flu.

Re:Covid-19: Do many people have pre-existing immunity? by guenthert on Thursday September 17, 2020 @04:07PM (#24509324)
I wonder whether skipping flu season is alike fire suppression in forests. When, not if, it eventually burns, it'll be that much more devastating.
Re:Covid-19: Do many people have pre-existing immunity? by throwaway0a5e on Thursday September 17, 2020 @11:30AM (#24505856)
>This doesn't pan out when children have developed severe inflammatory responses, young adults have died, and not all people with comorbidities have had severe reactions

How many millions has covid infected thus far? It would be concerning if it hadn't killed a couple healthy kids and not killed a couple obese old people.

Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @11:47AM (#24506070)
It's not "a couple", there's been about 105 child deaths, and 4600 child hospitalizations. It's not as bad as adults, but you can't say little Johnny is magically immune, nor can you say that Brad the football star at the local college is either. I don't think it's currently clear why some apparently healthy people develop severe reactions.
Re:Covid-19: Do many people have pre-existing immunity? by just-juan-post on Thursday September 17, 2020 @12:08PM (#24506375)
Do you feel we should restrict billions from gathering with and hugging their family so that we can save 105 children?

Can you help us understand the thinking you use to make that tradeoff?

Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @01:08PM (#24507176)
The point of the 105 dead children was to show children can be severely affected and don't have magic immunity. 500K children have been diagnosed with COVID, with varying symptom levels. We have 200,000 dead overall in the USA, so it's not just a matter of 105 dead children justifying lockdown, it's all those other dead people you seem to have forgotten about.

Also FYI, you can't hug your family member anymore once they're dead.

Re:Covid-19: Do many people have pre-existing immunity? by iso1631 on Thursday September 17, 2020 @02:30PM (#24508258)
They don't, but they are far more susceptible to Measles. In 2018 140,000 children died from measles -- a disease we actually have a well known vaccine that's been proven safe!
Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @02:50PM (#24508480)
Well we've yet to develop a COVID-19 vaccine that ditzy parents can ignore/avoid. Stupidity isn't an excuse for more stupidity.
Re:Covid-19: Do many people have pre-existing immunity? by neilwilson on Thursday September 17, 2020 @01:55PM (#24507772)
What’s the median age of those that have sadly passed and the percentage with comorbidities?
Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @02:09PM (#24507971)
Do you really mean "sadly" when trying to make the point that old people or people with pre-existing conditions are acceptable deaths?
Re:Covid-19: Do many people have pre-existing immunity? by seattletech on Thursday September 17, 2020 @03:23PM (#24508827)
Re:Covid-19: Do many people have pre-existing immunity? by neilwilson on Friday September 18, 2020 @04:07AM (#24514178)
Am I. Which part of the question is leading? Which part is not Socratic?
Re:Covid-19: Do many people have pre-existing immunity? by neilwilson on Friday September 18, 2020 @04:05AM (#24514170)
Well that would be an extremely unpleasant attempt at putting words in somebody's mouth that makes me wonder whether you are actually engaging honestly here.
Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Friday September 18, 2020 @01:44PM (#24519701)
Did you honestly not know the answer? What was your point?
Re:Covid-19: Do many people have pre-existing immunity? by michaelmrose on Thursday September 17, 2020 @02:17PM (#24508096)
This is emotional manipulation that we can all engage in. The 105 children are not the only victims.

I have bad asthma and my wife is ill I don't appreciate you gathering and hugging your family and killing mine.

Did that advance the discussion? Was it manipulation? No and you bet!

Re:Covid-19: Do many people have pre-existing immunity? by thelean12 on Thursday September 17, 2020 @05:12PM (#24510032)
It's small enough that it's not a concern and not something we should spend much effort worrying about. 105 is absolutely nothing compared to nearly 200k deaths in the US.

It's also a HUGE distraction to the real concern: We don't fully understand how contagious children are.

Re:Covid-19: Do many people have pre-existing immunity? by hervature on Thursday September 17, 2020 @11:55AM (#24506208)
Go here: https://www.cdc.gov/nchs/nvss/vsrr/covid19/excess_deaths.htm

Filter by 'Weekly Number of Deaths by Age' and you will see that it is literally the safest time ever for children and young adults because they are not allowed to go outside and do dumb stuff. Yes, some of them have died because of COVID, but the number is staggeringly small.

Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @11:57AM (#24506220)
Maybe fewer have died of covid because of lockdown?
Re:Covid-19: Do many people have pre-existing immunity? by username90 on Thursday September 17, 2020 @12:29PM (#24506665)
Sweden didn't close schools, 1 person under 20 has died out of about 2 million.
Re:Covid-19: Do many people have pre-existing immunity? by vkou on Thursday September 17, 2020 @01:04PM (#24507137)
How many people do people under 20 infect?

How many of those secondary infections die? How many of them stay sick for months?

There was a case right before schools opened in Georgia, I believe, of a kid who caught COVID at football practice. He's fine, but both of his parents died in a week.

Fortunately, he now no longer needs to worry about COVID. Unfortunately, he's now an orphan.

Re:Covid-19: Do many people have pre-existing immunity? by jtbayly on Thursday September 17, 2020 @01:35PM (#24507506)
And he's still proof that "few children get sick" from this.
Re:Covid-19: Do many people have pre-existing immunity? by vkou on Thursday September 17, 2020 @02:17PM (#24508092)
I did not realize that the sole metric that our society should optimize for, to the exclusion of all else is 'how many children get sick and die from COVID'.

(It's a very convenient optimization metric, though, because it requires us to do quite literally nothing.)

Re:Covid-19: Do many people have pre-existing immunity? by username90 on Thursday September 17, 2020 @02:56PM (#24508542)
Lots of people argue that children aren't dying because they were more locked down. For example the person I responded to. That is wrong, children aren't dying since covid doesn't hit them very hard. Children being vectors infecting others wasn't a part of this discussion.
Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @01:43PM (#24507614)
Children get sick, few have got sick enough to have died from it.
Re:Covid-19: Do many people have pre-existing immunity? by jtbayly on Thursday September 17, 2020 @11:30AM (#24505852)
It mostly does. Those cases you mention are quite rare.
Re:Covid-19: Do many people have pre-existing immunity? by belltaco on Thursday September 17, 2020 @12:29PM (#24506667)
>Factor in a glut of people who're living into advanced age, due to the progress of medical technology, so naturally in a precarious place against any infection

Then why does the annual flu not wipe out this population? Immunity lasts about 3 years so every such person who is exposed to the flu should be dying in one 3 year cycle.

Re:Covid-19: Do many people have pre-existing immunity? by treis on Thursday September 17, 2020 @01:23PM (#24507355)
Immunity lasts longer than 3 years:

>According to our study, it appears they can last the entire lifespan of the human organism — 90 years plus.

>n our study we were looking for antibodies to the 1918 flu. This flu virus was reconstructed a number of years ago in the lab, so we were able to test to see if 90 years later we could still find antibodies. I recruited survivors, people who were born in 1915 or earlier and thus presumably survived the 1918 flu. We found that virtually all the people born in 1915 or earlier — about 90% of them — had good "titers" to the 1918 flu, which means they still had reasonably high concentrations of the antibodies in their blood, whereas among controls, people who were born in 1926 or later, it was only about 10%. That was really quite a remarkable finding.

http://content.time.com/time/health/article/0,8599,1835907,0...

Re:Covid-19: Do many people have pre-existing immunity? by gligorot on Thursday September 17, 2020 @12:48PM (#24506906)
Wouldn't annual re-exposure to a similar virus "renew" the immunity?
Re:Covid-19: Do many people have pre-existing immunity? by gnusty_gnurc on Thursday September 17, 2020 @01:29PM (#24507426)
It does, in recent years, the flu death tolls have been below average mortality - Levitt's been looking at EuroMOMO for this.
Re:Covid-19: Do many people have pre-existing immunity? by aaronblohowiak on Thursday September 17, 2020 @01:00PM (#24507072)
Flu vaccination is pretty prevalent among seniors.
Re:Covid-19: Do many people have pre-existing immunity? by ineedasername on Thursday September 17, 2020 @01:05PM (#24507148)
Which reinforces the need to have vaccines to get to herd immunity, not just herd immunity except for seniors who will die a lot.
Re:Covid-19: Do many people have pre-existing immunity? by acqq on Thursday September 17, 2020 @11:34AM (#24505909)
No. "Obesity" and "vitamin-d deficiency" can't explain what happened in Italy (a lot of sun), and also can't explain what happened in the Nordic countries (much less sun), including Germany and Sweden (the later having order of magnitude more deaths than the former, measured as the percentage of the population). Sweden is particularly bad, having the deaths per capita even worse than the U.S. the last time I've checked.

What we see is that countries that were lucky enough to do strong enough prevention actions early enough had order of magnitude less deaths than those who didn't do them (and Sweden is in the latter camp, even if they did have more response than most admit -- they did close all universities, for example). The scale of deaths seen in New York would have never happened, had the use of masks been common early enough.

Eidt: Regarding "vulnerable populations" Italy and Germany have similar number of "vulnerable" and it seems Sweden would be better than Germany then:

https://commons.wikimedia.org/wiki/File:Population_pyramid_o...

https://commons.wikimedia.org/wiki/File:Population_pyramid_o...

https://commons.wikimedia.org/wiki/File:Sweden_population_py...

Re:Covid-19: Do many people have pre-existing immunity? by samsa on Thursday September 17, 2020 @11:49AM (#24506096)
It is worth noting that living in a sunny country does not guarantee the larger population receiving adequate Vitamin D through sun exposure, as many such populations somewhat paradoxically avoid sun exposure, as there are legitimate health reasons for doing so (extreme heat, concerns about skin cancer, etc.).
Re:Covid-19: Do many people have pre-existing immunity? by neilwilson on Thursday September 17, 2020 @01:56PM (#24507802)
India being the case in point where exposed skin is culturally unacceptable
Re:Covid-19: Do many people have pre-existing immunity? by acqq on Thursday September 17, 2020 @11:53AM (#24506171)
To support that you'd have to show that Italians have order of magnitudes higher deficiency than most of Nordic countries, and I don't think it is possible.

Another country with equivalent sun exposure to Italy is Greece, again orders of magnitude less deaths (like Germany). They also had strong lockdowns and early enough.

It's the measures. Analyzing what happened in Europe (and still happens) can't be explained with anything else.

Compare it with fires. Small fires are easy to extinguish. Pretending "it will go away" will simply result in a big fires. Eventually there won't be anything to burn. With people, eventually everybody who can and "feels the heat" will try to protect themselves.

A lot of older people in Sweden stay in their homes and take care not to be infected. Masks are common in the supermarkets, etc.

Re:Covid-19: Do many people have pre-existing immunity? by chucky on Thursday September 17, 2020 @12:33PM (#24506734)
> Masks are common in the supermarkets, etc.

Not sure where you got this information - masks are not commonly worn at all in Sweden. I see perhaps 1 mask per week, unless I go into the city center, then I might see 10 in a day.

The Swedish public health authorities are not currently recommending general usage of face masks, citing mainly the lack of evidence of the effectiveness of general mask usage (wearing a mask can cause you to get lulled into a false sense of security, for example).

See https://www.folkhalsomyndigheten.se/smittskydd-beredskap/utb...

(in Swedish, unfortunately)

Re:Covid-19: Do many people have pre-existing immunity? by username90 on Thursday September 17, 2020 @12:36PM (#24506765)
> To support that you'd have to show that Italians have order of magnitudes higher deficiency than most of Nordic countries, and I don't think it is possible.

Sweden adds vitamin D to food items so I wouldn't be surprised if Sweden has less vitamin D deficiency than many southern countries.

https://www.nutraingredients.com/Article/2015/05/28/Sweden-t...

Re:Covid-19: Do many people have pre-existing immunity? by gnusty_gnurc on Thursday September 17, 2020 @03:23PM (#24508829)
Can we find order of magnitude difference among darker skinned people? We've all heard about the disparity there.
Re:Covid-19: Do many people have pre-existing immunity? by Kiro on Thursday September 17, 2020 @12:48PM (#24506903)
> Masks are common in the supermarkets, etc.

This is outright false. I've been to a big supermarket twice this week and didn't see a single mask as far as I can recall.

Re:Covid-19: Do many people have pre-existing immunity? by clairity on Thursday September 17, 2020 @02:01PM (#24507863)
yes, masks are marginal at best, and as long as you're not spending a lot of time breathing another's direct exhaust, even indoors, you're at negligibly low risk of transmission.

i get super frustrated with the random corona rules at supermarkets in the US (like one-way only aisles, exit only doors), especially trader joe's, which is as draconian as it is arbitrary. for a while they weren't allowing you to take in your reusable grocery bags. later they relented and switched to just bagging your own groceries outdoors, leading to an awkward triple handling of your purchased items for what amounts to nothing other than safety theater.

for 6 months i've worn the same useless surgical mask to play my part in that misguided spectacle, when required. folks are slowly starting to realize their lack of utility, but have nothing else to latch onto because the obvious solution of modest distancing seems so mundanely unbelievable (and lacking obvious and spectacular conformance).

Re:Covid-19: Do many people have pre-existing immunity? by samsa on Thursday September 17, 2020 @01:29PM (#24507422)
For reference, see this article in the Lancet:

https://www.thelancet.com/journals/landia/article/PIIS2213-8...

Re:Covid-19: Do many people have pre-existing immunity? by acqq on Thursday September 17, 2020 @02:52PM (#24508512)
It's just an argument that the actual deficiency could cause worse outcome. But that article in Lancet doesn't claim that Italy had Vitamin D deficient population. The number of deaths per capita due to Covid-19 was however orders of magnitude higher in Italy and Sweden than in Germany. I don't think that there's anywhere any evidence that Germans are less Vitamin D deficient than Italians and Germans.

Vitamin D doesn't explain anything related to Covid-19 deaths in Europe, whereas the existence or lack of measures do, almost perfectly. Whoever can look at the curves of number of deaths since the begin of the epidemics, check the times of partial lockdowns or the introduction of some measures, can see that exactly around three weeks after these the curves stop going up and begin going down.

Italy as the first country seriously hit in Europe had the curve raising exponentially up until the measures started to work (there's a delay -- for people to stop dying the spread of infection has to turn first etc). Sweden also had the curve raising comparably to Italy, even if they had a negative example from Italy -- because there was a decision of targeting the "herd immunity". Germany's curve remained very low, as they had low prevalence at the time their measures started to be applied.

It's all about the measures and the adherence of the people to them.

Re:Covid-19: Do many people have pre-existing immunity? by samsa on Thursday September 17, 2020 @03:30PM (#24508905)
Many countries have Vitamin D deficient populations, including Italy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986426/

In Italy, it gets worse the older the population gets.

It is also an issue in Germany: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499202/

I make no claims other than: 1) there is a very strong correlation between vitamin D insufficiency/deficiency and poor outcomes for COVID-19, and 2) many populations, including those in sunny countries, suffer from widespread vitamin D insufficiency.

I for one have been taking 1,000 IUs of vitamin D every day since March, and trying to get sun exposure mid-day whenever I can.

Re:Covid-19: Do many people have pre-existing immunity? by acqq on Thursday September 17, 2020 @11:18PM (#24512628)
Look at the graph, it has obviously nothing to do with any deficiencies, and everything to do with the measures:

https://ourworldindata.org/coronavirus-data-explorer?zoomToS...

The comparison is possible because it’s per million. See Italy and Spain hit before they were aware what is going on., then introducing lockdowns.

See Sweden’s and the US denial, then limiting the initial outbreaks but continuing just not doing enough.

See Greece and Germany doing early enough good enough measures, and still doing it.

It’s that simple. The US not being aware how wrong they are doing is a crime to their own people. It’s historical failure.

You claim: “there is a very strong correlation between vitamin D insufficiency/deficiency and poor outcomes for COVID-19“ — show me that on the graph above. It’s obviously a red herring talking about Vitamin D once one sees it.

Re:Covid-19: Do many people have pre-existing immunity? by eCa on Thursday September 17, 2020 @12:18PM (#24506536)
> Sweden is particularly bad, having the deaths per capita even worse than the U.S. the last time I've checked.

No. USA: 608 per million. Sweden: 580. [1]

But the current trajectory is also important. In Sweden, the last day with more than 0.6 deaths/million was July 21 (according to actual date of death, not the date when death was reported), while the US currently is about 2-3 deaths/million/day.

[1] https://www.worldometers.info/coronavirus/

Re:Covid-19: Do many people have pre-existing immunity? by jahaja on Thursday September 17, 2020 @12:40PM (#24506813)
People really see what they want to see. As a Swede this whole pandemic has been truly enlightening regarding peoples propensity for confirmation bias. It has been truly shocking how prevalent it is throughout entire societies and ideologies.

Here in Sweden the right-wing folks want to lock everything down and the left-wing want to keep deferring it to the experts. In the rest of the world it seems to be the other way around.

Re:Covid-19: Do many people have pre-existing immunity? by natrik on Thursday September 17, 2020 @01:59PM (#24507828)
Can you provide some articles/material regarding right wingers wanting to lock things down in Sweden? I'm not familiar with Swedish politics and would be interested in reading more.
Re:Covid-19: Do many people have pre-existing immunity? by username90 on Thursday September 17, 2020 @03:16PM (#24508736)
The debate is pretty calm compared to USA, most politicians agree with the general strategy so the opposition mostly criticize the execution.

https://www.thelocal.se/20200530/swedish-opposition-demands-...

Re:Covid-19: Do many people have pre-existing immunity? by Kiro on Thursday September 17, 2020 @05:01PM (#24509911)
I wish this complete upside-down debate would get more attention in international media but it's truly the reverse of what's happening in the US.

While the official stance for all parties is that they support the strategy (the most right-wing party being the exception who is heavily criticizing it), it's more telling in social media.

Hanif Bali, one of the most prominent right-wing figures in social media, has really been pushing for lockdowns/masks and is cheered on by his tail of alt-right followers. Meanwhile the left is mocking him, lockdowns and masks in general.

Re:Covid-19: Do many people have pre-existing immunity? by jahaja on Thursday September 17, 2020 @03:15PM (#24508734)
Throughout the pandemic the (neo-)Liberal (right-wing by Swedish standards) newspaper Dagens Nyheter (Today's News, dn.se) have led a campaign criticising the Swedish lax approach. The news site is paywalled however.

The leader of the Swedish Democrats, the most right-wing in the Swedish parliament, called for the state epidemiologist, Anders Tegnells, to take responsibility and resign immediately: https://www.expressen.se/nyheter/jimmie-akesson-tegnell-mast...

Interesting enough it's also the same kind of fringe-right that are protesting in against restrictions in Germany that is calling our approach genocidal here:

"Tegnell is a danger to society" https://projektsanning.com/2020/03/12/coronaviruset-statsepi...

"Tegnell reported to the Police due to the mass death among elderly" https://www.friatider.se/tegnell-polisanmald-massdoden-bland...

Re:Covid-19: Do many people have pre-existing immunity? by jtbayly on Thursday September 17, 2020 @01:38PM (#24507539)
Another way of looking at it: the left-wing people everywhere want to defer to the experts. It's just that the experts in different places are saying different things.
Re:Covid-19: Do many people have pre-existing immunity? by ynfnehf on Thursday September 17, 2020 @02:11PM (#24508022)
Sweden has 5x deaths of Germany. Not quite an order of magnitude. And as someone else pointed out, the US has more deaths per capita than Sweden.
Re:Covid-19: Do many people have pre-existing immunity? by shpeedy on Thursday September 17, 2020 @04:41PM (#24509720)
5x is order of magnitude larger. Quote:

Generally, the order of magnitude of a number is the smallest power of 10 used to represent that number.[2] To work out the order of magnitude of a number N, the number is first expressed in the following form:

    N = a × 10^b
where 1/sqrt(10) ≤ a < sqrt(10) . Then, b represents the order of magnitude of the number.

https://en.wikipedia.org/wiki/Order_of_magnitude

Re:Covid-19: Do many people have pre-existing immunity? by acqq on Thursday September 17, 2020 @03:05PM (#24508639)
> the US has more deaths per capita than Sweden

Nothing to be proud about for either of them. Anyway, until e.g. month ago Sweden had the lead.

Re:Covid-19: Do many people have pre-existing immunity? by acqq on Saturday September 19, 2020 @10:17AM (#24527592)
Just checked: it seems the last day the U.S. was better than Sweden in deaths per capita was 11. September, so just 8 days ago. And, when the trends continue, in a week the U.S. will be worse than the U.K. too. The only countries in Europe with more Covid-19 deaths per million then will be Belgium and Spain.
Re:Covid-19: Do many people have pre-existing immunity? by ynfnehf on Saturday September 19, 2020 @10:38AM (#24527703)
If I recall correctly the US passed Sweden in excess mortality sometime in June/July. So they have probably passed some of the other European countries already. I couldn't find a good up to date source, but Belgium seems to have lower excess than US. Comparing death statistics is not trivial.

Anyways, I don't think comparing the US to most countries in Europe really makes sense, considering the size and population differences.

Re:Covid-19: Do many people have pre-existing immunity? by acqq on Saturday September 19, 2020 @01:07PM (#24528868)
> If I recall correctly the US passed Sweden in excess mortality sometime in June/July.

According to ourworldindata, in reported Covid-19 deaths per million, on Sept 12:

https://ourworldindata.org/coronavirus-data-explorer?zoomToS...

> I don't think comparing the US to most countries in Europe really makes sense

You are missing "per million" which is what I used. Comparing absolute numbers has of course no sense. When comparing relative numbers ("per million"), the big country spread across big area, like U.S. is, would be expected have huge advantages compared to any country in Europe (due to slower spread over the distances, much less dependency on public transportation). Moreover, the countries worst hit in Europe were only those where the spread happened first -- others took note and introduced measures early enough. Not the U.S. which totally botched its response even ignoring the initial hit in NY. Compare the slopes of all other European countries for months, v.s. what's going on in the U.S. The response in the U.S. is criminally bad, and continues to be so -- and not looking at the "cases" but simply and tragically, deaths. Those that are reported.

I admit that comparing some other estimates of "excess deaths" could give some other numbers, but I don't see any way in which U.S. can look good, especially as it was Italy being hit the first and everybody else having the time to react somehow.

Also see daily average of deaths per million, to get the idea how bad it is still:

https://ourworldindata.org/grapher/daily-covid-deaths-per-mi...

Re:Covid-19: Do many people have pre-existing immunity? by gnusty_gnurc on Thursday September 17, 2020 @12:06PM (#24506352)
I said the interplay of chronic disease, vitamin-d and vulnerable populations.
Re:Covid-19: Do many people have pre-existing immunity? by andy_ppp on Thursday September 17, 2020 @11:12AM (#24505594)
I keep wondering if the immunity to these viruses disappears while in lockdown causing a much more severe second wave than expected...
Re:Covid-19: Do many people have pre-existing immunity? by yomly on Thursday September 17, 2020 @11:23AM (#24505755)
Don't know why you were down voted - I take your position to mean "has lockdown led to a loss of general immunity due to lack of exposure to general pathogens" which I think is a valid question to ask.

Seems some people are too trigger happy and unwilling to explore charitable interpretation of posts.

Re:Covid-19: Do many people have pre-existing immunity? by andy_ppp on Thursday September 17, 2020 @11:33AM (#24505893)
Precisely, it’s not as if we don’t know from other pandemics that the second wave is almost always more severe... I’m not suggesting we go full Sweden and start coughing on each other in the sauna, but there are lots of factors we are struggling to account for in all this.
Re:Covid-19: Do many people have pre-existing immunity? by dehrmann on Thursday September 17, 2020 @09:41PM (#24512065)
The answer is probably "we don't know." The closest example I can think of for this is what the immune systems of ISS astronauts look like after 6 months in orbit.

Listening to epidemiologists alone was/is a bad choice because they study the spread of disease. You also to consider long-term effects on the immune system, the economy, education, social structure, politics.

The second-order effects have already been surprising:

- Social unrest in the US - China restricting freedoms in Hong Kong - Bifurcated "K" economy - Covid case surges in countries that "did it right" with hard lockdowns

Re:Covid-19: Do many people have pre-existing immunity? by michaelmrose on Thursday September 17, 2020 @02:24PM (#24508191)
It's a bad theory with no medical evidence.
Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @11:31AM (#24505874)
The article and your wondering doesn't provide enough evidence that we should go counter to not trying to spread the virus in the first place. Social distancing, hygiene and a vaccine are much more definitive ways to combat a severe second wave than hoping magically some people have built-in immunity or some unknown environmental trigger results in a similar immune response.
Re:Covid-19: Do many people have pre-existing immunity? by yomly on Thursday September 17, 2020 @03:17PM (#24508750)
The parent never suggested anything anti-lockdown. At face value it is merely questioning the existence of a possible trade off of lockdown. As you've not provided evidence or anecdotal stories to refute the question I'm still in no better position to consider the parent's question with more information.

I mean if we really want to start projecting our own agendas or anti agendas, the whole notion of "evidence" leaves a bad taste in my mouth given the WHO went on record saying "there is no evidence of human transmission". And I am saying this as a scientist!

Our obsession with evidence and data is important (as what are we without empiricism) but boy has it seemed more like a curse rather than a blessing at various stages throughout this pandemic. I am definitely team Bayes on these matters, common sense and experience do hold some value sometimes.

Re:Covid-19: Do many people have pre-existing immunity? by Klinky on Thursday September 17, 2020 @04:32PM (#24509616)
Germ theory and the science around vaccines is well established. Winging it because maybe some unknown might protect us sounds absurd. To get to the point where the existence of this unknown can be proven yes/no will take longer than it will to develop a vaccine.
Re:Covid-19: Do many people have pre-existing immunity? by yomly on Thursday September 17, 2020 @07:11PM (#24511081)
I never questioned germ theory nor the science of vaccines.

I do raise an eyebrow however when there's so much rigmarole around "evidence" and mask wearing. Just like there was rigmarole around hand washing when Semmelweis promoted it. What a bizarre hill people have made to die on.

And how slow the WHO were to declare the dangers of covid in its early stages.

Re:Covid-19: Do many people have pre-existing immunity? by subsubzero on Thursday September 17, 2020 @03:04PM (#24508629)
I completely agree with this hypothesis, it explains why groups so disparate have all seen similar outcomes(low instances of severe covid:

-homeless

-celebrities

-children

What do all these groups have in common?

Age? well count out celebrities, ie. Tom Hanks, Prince Philip(both are in advanced age).

Good health? I'd count out homeless as a lot suffer from chronic ill-health.

Weight? Some heavier celebrities have had covid and been fine, its an important metric though.

Exposure to a lot of viruses? Yes, all three groups are in constant exposure to a multitude of viruses, from children in daycare, to celebrities interacting with tons of people to always traveling, to homeless getting exposed to viruses in trash and living in unsanitary conditions.

Re:Covid-19: Do many people have pre-existing immunity? by teorema on Thursday September 17, 2020 @03:51PM (#24509152)
I've been wondering this since the beginning, as a parent of a relatively small child in preschool.

I've had one prediction all along, which is that parents of small children would probably also have lower rates of symptomatic disease, lower severity, etc. than matched controls, because they'd also be exposed to prexisting coronaviruses and therefore have some cross-immunity.

You could probably extend this to other groups too.

I admit it might be totally wrong but it seems straightforward to test with the right data, and if it were wrong that would also be interesting.

Re:Covid-19: Do many people have pre-existing immunity? by notatoad on Thursday September 17, 2020 @01:26PM (#24507377)
>one or more very similar viruses have been in circulation for a while

the genetic makeup of covid-19 has been well studied and this is not the case. If it were multiple different diseases, it would be very obvious.