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Re:Vitamin D supplementation to prevent acute respiratory tr... by leto_ii on Monday March 02, 2020 @07:56AM (#22463950)
I can say from my own experience that the lack of vitamin D can have a significant impact on both mind and body.

I suspect that essentially all people living at relatively northern latitudes have some sort of vitamin D deficiency. From what I know you need to have your face and arms exposed to direct sunshine for at least 15 minutes/day to keep healthy vitamin D levels in the body. Good luck with that in the European/Canadian/Northern US winter.

Re:Vitamin D supplementation to prevent acute respiratory tr... by BurningFrog on Monday March 02, 2020 @09:58AM (#22464909)
This is one reason arctic people eat so much (vitamin D rich) fish. The other is of course that a plant based diet is impractical when plants are only alive half the year.

White skin itself is an evolutionary adaption for getting enough vitamin D outside of tropical Africa. The extreme "melanin-anemic" blond & blue eyes look of Scandinavia is thought to be because it has a uniquely warm weather for the latitude, which make it possible to grow (vitamin D poor) grains there. That supports by far the biggest population density that far north, but also induces extreme whiteness to soak up every possible sun ray.

Conversely, if you have dark skin and live in the non tropics, you absolutely need to monitor and enhance your vitamin D intake. Sadly, doctors don't seem to bring this up with dark skinned patients, at least from what I hear from my (OK, not that many...) black friends.

Re:Vitamin D supplementation to prevent acute respiratory tr... by alexpotato on Monday March 02, 2020 @10:55AM (#22465408)
I don't have the source handy but there was a geographic point made about Scandinavia that went something like this:

- Scandinavia is very far north and therefore gets less sun in the winter (obviously)

- Apparently the soil of Scandinavia is well suited to crops that are high in Vitamin D

The soil being good for Vitamin D crops (plus lightening of skin/hair and fish diets etc) was a part of why people were able to live in such far northern climates even if they didn't always have access to fish.

Re:Vitamin D supplementation to prevent acute respiratory tr... by bdcs on Monday March 02, 2020 @01:35PM (#22467286)
> - Apparently the soil of Scandinavia is well suited to crops that are high in Vitamin D

IIUC it's the other way around. soil/climate allows for foods low in Vitamin D -> Vitamin D needed from other sources -> evolutionary pressure for getting it from the sun -> less melanin in skin

Re:Vitamin D supplementation to prevent acute respiratory tr... by BurningFrog on Monday March 02, 2020 @02:04PM (#22467626)
I can't find any crops that are high in vitamin D.

Some fungi have decent vitamin D, but it's certainly not a major "crop" in Scandinavia.

Re:Vitamin D supplementation to prevent acute respiratory tr... by wdobbels on Monday March 02, 2020 @10:35AM (#22465222)
I'm probably missing something obvious but... Should white skin not reflect sunlight more, and dark skin absorb it more? I agree that northerners have more need to absorb sunrays and hence make more vitamin D, so shouldn't they be black?
Re:Vitamin D supplementation to prevent acute respiratory tr... by pdonis on Monday March 02, 2020 @11:21AM (#22465748)
> Should white skin not reflect sunlight more, and dark skin absorb it more?

"White" and "dark" refer to the skin's effects on visible light. Visible light is different wavelengths from UV light; vitamin D production in the skin depends on UV light. "Dark" skin blocks UV light more than "white" skin does.

Re:Vitamin D supplementation to prevent acute respiratory tr... by BurningFrog on Monday March 02, 2020 @10:42AM (#22465286)
Yeah, it's confusing.

I think this is how it works: The melanin is not transparent, so it stops the light from penetrating beyond the very surface, and so a smaller volume of skin cells get access to sunlight.

To go a little deeper: Sunlight does two major things in our skin. It creates vitamin D, and destroys folate. Both are essential, so the various skin colors we have reflect the balance evolution has struck in various environments.

Re:Vitamin D supplementation to prevent acute respiratory tr... by leto_ii on Monday March 02, 2020 @10:43AM (#22465313)
Nope. Dark skin is an adaptation to exposure to lots of UV rays: https://en.wikipedia.org/wiki/Melanin#Evolutionary_origins

Incidentally you can test this yourself: if you go out in the summer you will tan i.e. your skin will darken. This is adaptation to lower the risk of sunburn and skin cancer.

Re:Vitamin D supplementation to prevent acute respiratory tr... by hcarvalhoalves on Monday March 02, 2020 @10:41AM (#22465283)
Vitamin D synthesis happens underneath the skin, and requires UV B radiation. The dark skin is an adaptation to avoid UV damage from the normal UV levels you get at the less extreme latitudes by filtering out most of it.
Re:Vitamin D supplementation to prevent acute respiratory tr... by jshevek on Monday March 02, 2020 @12:34PM (#22466584)
Evolution makes adaptations to what it already has, unlike a sentient designer who might create an optimal design then look for ways to implement it.

If you could design a human from scratch, it might be most efficient to give northerners a D synthesizing pigment that's opaque in the necessary wavelength, resulting in the situation you describe.

Instead we have protective pigments near the surface, synthesizing structures underneath, and a need to balance D synthesis against UV damage.

Re:Vitamin D supplementation to prevent acute respiratory tr... by dreamcompiler on Monday March 02, 2020 @12:45PM (#22466721)
It's not obvious; this confused me for a long time. The skin we call "white" is fairly transparent to UV, and the skin we call "black" is much less so. Skin is a mixture of transparency and reflectivity at different wavelengths and different depths below the surface. As such it's extraordinarily difficult to model it so it looks right, as any CGI engineer will tell you.
Re:Vitamin D supplementation to prevent acute respiratory tr... by pygy_ on Monday March 02, 2020 @10:40AM (#22465270)
Melanin is deposited in the epidermis, vitamin D conversion happens deeper, in the blood vessels of the dermis.
Re:Vitamin D supplementation to prevent acute respiratory tr... by Florin_Andrei on Monday March 02, 2020 @12:57PM (#22466861)
The dark (or not so dark) layer is quite superficial, not far from surface. But the vit D production happens deeper in. For sun rays to get there, that layer must be light-colored.

Sure, some photons do get reflected, but the benefit is from those photons that get deeper into the skin.

Re:Vitamin D supplementation to prevent acute respiratory tr... by Raphmedia on Monday March 02, 2020 @10:44AM (#22465322)
Melanin in dark skin doesn't absorb as much UV radiation. It makes sense for people who live under the sun with relatively little protection to be dark skinned but it wouldn't make sense for people who are rarely exposed to the sun to be resistant to it.
Re:Vitamin D supplementation to prevent acute respiratory tr... by ahakki on Monday March 02, 2020 @10:43AM (#22465309)
IIRC from high school biology, the melanin in the upper skin layer absorbs the sunlight thus preventing it from going any deeper into the skin.
Re:Vitamin D supplementation to prevent acute respiratory tr... by chabes on Monday March 02, 2020 @11:39AM (#22465963)
Ummm, plants are alive longer than “half the year“. Humans have also preserved foods for out of season consumption for millennia. Natives in California had plenty of plant-based foods in winter months.
Re:Vitamin D supplementation to prevent acute respiratory tr... by Robotbeat on Monday March 02, 2020 @11:57AM (#22466161)
"California" being the operative word, there. Oslo, Norway has a 60 degree latitude. Sacramento has a 35.8 degree latitude.
Re:Vitamin D supplementation to prevent acute respiratory tr... by chabes on Monday March 02, 2020 @01:07PM (#22466989)
Most humans live closer to 27 degrees north of the equator. I mentioned California natives because that’s what I’m most familiar with. Plant preservation is a thing in northern latitudes too..
Re:Vitamin D supplementation to prevent acute respiratory tr... by bdamm on Monday March 02, 2020 @11:58AM (#22466187)
Natives in California can still be harvesting in November and can see the ground all year round except in the mountains. Natives at the far north might be done with harvesting by late September or early October and might not see the ground again until April. Not even remotely comparable in terms of the severity of the issue and the impact to survival.
Re:Vitamin D supplementation to prevent acute respiratory tr... by chabes on Monday March 02, 2020 @01:08PM (#22467000)
Natives in the far north still preserve food for consumption during winter months.
Re:Vitamin D supplementation to prevent acute respiratory tr... by BurningFrog on Monday March 02, 2020 @04:50PM (#22469438)
Sure, the plants are alive as roots, seeds etc under the snow, but they have nothing edible to offer, so for the purposes of nutrition, they might as well be dead.
Re:Vitamin D supplementation to prevent acute respiratory tr... by thinkingemote on Monday March 02, 2020 @08:18AM (#22464099)
Its not possible to get any vitamin D from the sun in the winter in these high latitudes even if you outside in the sun all day with short sleeves. The angle of the sun is too low. We are just beginning march now, so the sun should soon be beginning to be high enough to give some benefit.
Re:Vitamin D supplementation to prevent acute respiratory tr... by kaztal on Monday March 02, 2020 @09:26AM (#22464663)
Sweden here. My partner is a doctor, she claims with assurance that you can't make a carpet decision like this. People who come from norther latitudes are used to the lack of sun, and their bodies don't need more vitamin D than is provided. Depending on your heritage, ymvm.
Re:Vitamin D supplementation to prevent acute respiratory tr... by BurningFrog on Monday March 02, 2020 @10:00AM (#22464920)
Swedes need as much vitamin D as anyone, but usually get it from their diet. Herring is a vitamin D gold mine, for example :)
Re:Vitamin D supplementation to prevent acute respiratory tr... by abainbridge on Monday March 02, 2020 @11:08AM (#22465581)
That seems implausible. Obviously there was evolutionary pressure on northern Europeans to tolerate lower levels of sunlight and no doubt adaption happened. However, I expect even Swedes evolved in an environment that included more time outdoors than a modern Swedish office worker gets. So, in the absence of any actual evidence, I'd still expect a problem. On top of that, there is some evidence. Basically all the papers found by this search show some evidence of vitamin D deficiency in Swedish people: https://scholar.google.com/scholar?start=10&q=sweden+vitamin...
Re:Vitamin D supplementation to prevent acute respiratory tr... by SketchySeaBeast on Monday March 02, 2020 @11:51AM (#22466100)
The first two articles I get from that search looks at vitamin d and the older population, and the third[1] suggests that even in sub-arctic elevations "Adequate levels were found in 79.2%, more often in women (82.7%) than in men (75.6%). Only 0.7% of the population were vitamin D3–deficient but 23.1% of men and 17.1% of women had insufficient levels." That doesn't seem too damning.

At the end of the day I don't know enough, so I'm not making the claim about Vitamin D quantities, but isn't the evidence that there was at least some form of adaptation evident based upon skin tone alone?

https://www.tandfonline.com/doi/full/10.3402/ijch.v74.27963

Re:Vitamin D supplementation to prevent acute respiratory tr... by abainbridge on Monday March 02, 2020 @01:04PM (#22466945)
I already agreed there was adaption. I just can't see how there can have been adaption for an _indoor_ life at northern latitudes. That's doubly hard, compared to a traditional life in northern latitudes, right? Although, to argue against myself, I guess if you go far enough north, people won't be getting any sunlight in the winter even if they are outdoors all the time. People there must have adapted to that. I guess by eating things with lots of vitamin D.
Re:Vitamin D supplementation to prevent acute respiratory tr... by nitrogen on Monday March 02, 2020 @12:31PM (#22466557)
I wonder, have any northern populations developed an instinctive winter hibernation adaptation?
Re:Vitamin D supplementation to prevent acute respiratory tr... by therealcamino on Monday March 02, 2020 @01:10PM (#22467025)
I love the phrase "carpet decision". Although we don't have it in English, I'm guessing it's roughly equivalent to "blanket statement", something that applies in all cases without exception?
Re:Vitamin D supplementation to prevent acute respiratory tr... by preben on Monday March 02, 2020 @02:34PM (#22467949)
Very much what I meant. Happy the meaning went through.
Re:Vitamin D supplementation to prevent acute respiratory tr... by leto_ii on Monday March 02, 2020 @09:30AM (#22464695)
It may still be worth taking a blood test, especially if you have some symptoms that match vitamin D deficiency.
Re:Vitamin D supplementation to prevent acute respiratory tr... by v77 on Monday March 02, 2020 @09:45AM (#22464811)
Most people in North America are not from northern latitudes genetically unless we are talking about the UK and Germany and even then..
Re:Vitamin D supplementation to prevent acute respiratory tr... by orasis on Monday March 02, 2020 @10:18AM (#22465061)
Huh? Europe is generally populated further north than North America is.
Re:Vitamin D supplementation to prevent acute respiratory tr... by dreamcompiler on Monday March 02, 2020 @12:56PM (#22466850)
It doesn't work in the binary fashion you described. Low sun angles have two results: Cosine effect and greater atmospheric absorption. The cosine effect decreases the watts per square meter you receive, if your skin is not normal (90 degrees) to the incident sunlight. Greater atmospheric absorption means more UVB is absorbed by the atmosphere before it gets to you, but some still gets through, as anyone who has ever been sunburned in the winter can attest. Higher altitudes and snow on the ground both increase the amount of UVB you receive, even when the sun is low.
Re:Vitamin D supplementation to prevent acute respiratory tr... by MatthiasP on Monday March 02, 2020 @11:15AM (#22465680)
Do you have a source for that? Even at a lower angle you still get some UV B and energy from the sun.
Re:Vitamin D supplementation to prevent acute respiratory tr... by bproven on Monday March 02, 2020 @09:09AM (#22464551)
Yep - I learned that a few years ago.
Re:Vitamin D supplementation to prevent acute respiratory tr... by TacoToni on Monday March 02, 2020 @08:15AM (#22464078)
getting my blood panel ran and finding out i was deficient in Vitamin D changed my life for the better once i start daily supplementation of Vitamin D3 (5000 IU). I even live in Florida, but working in an office all day doesn't help. Now that my levels are good, i feel as if my memory is far better and i dont feel tired all the time.
Re:Vitamin D supplementation to prevent acute respiratory tr... by leto_ii on Monday March 02, 2020 @08:23AM (#22464133)
> i feel as if my memory is far better and i dont feel tired all the time.

I agree. Don't overdo it though, 5000 IU daily seems a bit much :) I live in Amsterdam and take 2000.

Re:Vitamin D supplementation to prevent acute respiratory tr... by chrismeller on Monday March 02, 2020 @10:14AM (#22465039)
There have actually been a couple of studies lately about Vitamin D recommendations being drastically too low. For example [1] recommends 4000 IU/day for adults and [2] recommends 8000 IU/day.

1: https://www.medscape.com/viewarticle/744128 2: https://www.ncbi.nlm.nih.gov/m/pubmed/28768407/

Re:Vitamin D supplementation to prevent acute respiratory tr... by speakeron on Monday March 02, 2020 @08:31AM (#22464210)
I take about 5000 IU daily (with one or two days off every 10 days or so). I get tested regularly and measure at the top of the lab's 'normal range' (200 nmol/l). I also take vitamin K (especially K2).
Re:Vitamin D supplementation to prevent acute respiratory tr... by pdonis on Monday March 02, 2020 @11:24AM (#22465780)
> 5000 IU daily seems a bit much

I think it depends on the person. If you get your blood level checked when you have a regular physical, you can adjust the dose as needed to keep the level where you want it (I shoot for the upper end of the normal range, and 5000 IU a day seems to be doing that for me).

Re:Vitamin D supplementation to prevent acute respiratory tr... by blaser-waffle on Monday March 02, 2020 @12:55PM (#22466836)
Canada here. "Central Canada" aka reasonably far up.

2000 IU a day, 3-5 days a week. Not strict about it, just whenever I remember. Big difference in terms of energy, depression, sleep quality, etc.

I've messed around with higher levels but they usually give me wicked headaches.

Re:Vitamin D supplementation to prevent acute respiratory tr... by ArikBe on Monday March 02, 2020 @09:11AM (#22464563)
Out of personal curiosity, what supplement brand do you take? I live in Ams as well and the season is...horrible.
Re:Vitamin D supplementation to prevent acute respiratory tr... by aries1980 on Monday March 02, 2020 @12:36PM (#22466605)
I take GAL D3 or D-complex+K2 Forte (https://www.gal.hu/en/spd/VIGAD303001/GAL-D3-vitamin and https://www.gal.hu/en/spd/VIGAKKF02001/GAL-K-complex-Forte). They are quite transparent on how they source and extract the ingredients.
Re:Vitamin D supplementation to prevent acute respiratory tr... by leto_ii on Monday March 02, 2020 @10:09AM (#22464997)
Currently I take the one from physalis: https://www.hollandandbarrett.nl/shop/product/physalis-vitam...

You can probably play around with the brands and doses a little. I think the important thing is to take gel capsules with oil inside and not solid pills. Vitamin D is fat-soluble so I think solid pills don't get absorbed very well.

Re:Vitamin D supplementation to prevent acute respiratory tr... by netheril96 on Monday March 02, 2020 @08:30AM (#22464196)
The FDA's recommendation for Vitamin D daily value is 400 IU. 5000 IU seems extremely and poisonous.
Re:Vitamin D supplementation to prevent acute respiratory tr... by SamBam on Monday March 02, 2020 @10:20AM (#22465078)
There is research showing that the figure of 400 IU is based on a statistical error [1] (that's the original article, there's plenty more if you search).

Most articles I have read recommend somewhere between 2000 and 5000 IUs. Some recommend higher.

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210929/

Re:Vitamin D supplementation to prevent acute respiratory tr... by elric on Monday March 02, 2020 @08:49AM (#22464362)
The body can produce up to 25000 IU/day in very sunny places on very pale skin. 10000IU/day is considered the safe upper limit. Whether or not that's a good idea long term is a different matter.
Re:Vitamin D supplementation to prevent acute respiratory tr... by jcampbell1 on Monday March 02, 2020 @10:07AM (#22464981)
The body can produce over 250,000 IU in short order delivered as 25,000 IU a day as a controlled release through the skin. If you want this, the best idea is to spend 5 minutes in your underwear in a tanning bed. Dietary supplements can work, but it takes months.
Re:Vitamin D supplementation to prevent acute respiratory tr... by alaaf on Monday March 02, 2020 @08:40AM (#22464284)
It actually isn’t. 400 IU is based on preventing disease. To obtain optimal health though, dosages should usually be much higher. Obviously this differs from person to person, but 2000 IU should lead to optimal vitamin D levels. This is an interesting video on the topic: https://www.youtube.com/watch?v=jeLC_b5gDUM
Re:Vitamin D supplementation to prevent acute respiratory tr... by anamexis on Monday March 02, 2020 @08:34AM (#22464233)
My MD prescribed me 5000 IU / day after a blood panel came back with me on the low end of healthy.
Re:Vitamin D supplementation to prevent acute respiratory tr... by ssully on Monday March 02, 2020 @10:33AM (#22465202)
Same. He wanted to do it after asking if I worked in an office, and the results came back pretty low.
Re:Vitamin D supplementation to prevent acute respiratory tr... by davidw on Monday March 02, 2020 @12:09PM (#22466305)
> your face and arms exposed to direct sunshine for at least 15 minutes/day

I wonder what the actual numbers are for this. This weekend, I got out for a couple of 3 hour bike rides, for instance, but it was chilly out, so nothing but my face was exposed.

Re:Vitamin D supplementation to prevent acute respiratory tr... by logfromblammo on Monday March 02, 2020 @01:51PM (#22467463)
The reaction is as follows:

7-dehydrocholesterol --(UVB @ 296nm)--> previtamin-D --(thermal isomerization)--> cholecalciferol

The first step reaches equilibrium after about 15 minutes in Fitzpatrick type 1 skin in UV index 3-5 (moderate), and about 2 hours in Fitzpatrick type 6. The total amount produced is dependent on the surface area of exposed skin, and the previtamin isomerizes slowly, over about 12 days.

Time to equilibrium is about half the time to acquire sunburn at a UV index high enough to catalyze the previtamin-D reaction. At UV index 6-7 (high), time to burn is about the same as the time to reach previtamin-D equilibrium. At UV index 8 or higher (very high), you will burn faster than you make previtamin-D, and should maybe avoid being exposed during the midday hours. At UV index 11 or higher (extreme), if you are Fitzpatrick type 1, you will carbonize to a burnt matchstick the instant you step out of shadow, like a cartoon vampire, and you should not only not be outside, but should also be huddling in a dark basement waiting on the tyranny of the sun to pass.

Thanks to the equilibrium in the skin, the maximum absorbed dose from sunlight is the equivalent of about 20000 IU per day. High vitamin-D intake also requires increased vitamin-K consumption to reduce calcification of soft tissues.

Re:Vitamin D supplementation to prevent acute respiratory tr... by pdonis on Monday March 02, 2020 @11:19AM (#22465718)
> you need to have your face and arms exposed to direct sunshine for at least 15 minutes/day to keep healthy vitamin D levels in the body

Even that might not be enough, since in many people the body's ability to synthesize vitamin D when exposed to sunlight decreases with age. The only way to know for sure where you stand is to get your blood levels checked when you get a physical, and supplement if you need to.

Re:Vitamin D supplementation to prevent acute respiratory tr... by GordonS on Monday March 02, 2020 @02:26PM (#22467844)
As a single, contrary data point, I live in the North of Scotland, and get very little sunlight - I started taking 4,000 IUs a day of vitamin D around a year ago, but haven't noticed any difference whatsoever.
Re:Vitamin D supplementation to prevent acute respiratory tr... by Florin_Andrei on Monday March 02, 2020 @12:58PM (#22466879)
I probably had life-long chronically low levels of vitamin D. Taking supplements was a major change for me - basically everything got better.

This sort of thing is impossible to diagnose correctly without lab tests.

Re:Vitamin D supplementation to prevent acute respiratory tr... by _d03 on Monday March 02, 2020 @08:24AM (#22464142)
What about DHA/EPA? Iodine and vitamin B1?

Our modern diets could cause further nutritional deficiencies. I doubt that many people in the West eat fish regularly or supplement with algae oil due to the conveniences of processed food. Same with iodine. Wheat germs have the highest concentrations in vitamin B1, but whole grains in general (rolled oats etc.) are good so you should probably cut the processed food out as much as possible.

Re:Vitamin D supplementation to prevent acute respiratory tr... by dr_coffee on Monday March 02, 2020 @08:34AM (#22464235)
True iodine deficiency is quite rare in the west as many table salts are fortified with iodine. It is extremely uncommon to see people with Goiter in the US. The same goes for thiamine/B1 deficiency which used to cause cardiovascular and neurological disease in alcoholics, but is now very rare becuse many pastas/breads/cereals are fortified with B1.
Re:Vitamin D supplementation to prevent acute respiratory tr... by aries1980 on Monday March 02, 2020 @12:42PM (#22466677)
In the UK, you can barely find table salt that has iodine. The one has the right potassium/sodium ratio with iodine (e.g. Iodized LoSalt) is zero.
Re:Vitamin D supplementation to prevent acute respiratory tr... by leto_ii on Monday March 02, 2020 @08:29AM (#22464187)
It can be that there are other hidden deficiencies. Vitamin D was the most surprising for me though because I wasn't aware that you can't really find it in food and that it's only synthesized in the skin in the presence of UV rays.
Re:Vitamin D supplementation to prevent acute respiratory tr... by pmoriarty on Monday March 02, 2020 @07:05PM (#22470499)
My biggest surprise: even meat eaters can have Vitamin B12 deficiency.

My doctor recommends all his patients supplement with B12, regardless of whether they're vegetarian, because of the above mentioned potential for everyone to have B12 deficiency, and, according to him, tests for B12 aren't reliable.

Re:Vitamin D supplementation to prevent acute respiratory tr... by joncrane on Monday March 02, 2020 @12:08PM (#22466297)
>you can't really find it in food

Pretty sure that's the reason almost all milk in the USA is fortified with Vitamin D (and A)

Re:Vitamin D supplementation to prevent acute respiratory tr... by egeozcan on Monday March 02, 2020 @08:19AM (#22464106)
South European winter is pretty okay, IMHO. Especially South Turkey and Cyprus, if we are not strictly speaking about Europe the continent.
Re:Vitamin D supplementation to prevent acute respiratory tr... by oblio on Monday March 02, 2020 @09:14AM (#22464583)
I'd say anything South of Prague is probably ok. Even if the winters are cold, the sun is still shining for a long part of winter.
Re:Vitamin D supplementation to prevent acute respiratory tr... by all_blue_chucks on Monday March 02, 2020 @02:10PM (#22467683)
One's person experience is not meaningful for a population.
Re:Vitamin D supplementation to prevent acute respiratory tr... by animalnewbie on Monday March 02, 2020 @12:21PM (#22466442)
> 15 minutes

Depends on your own skin color too.

Re:Vitamin D supplementation to prevent acute respiratory tr... by econcon on Monday March 02, 2020 @09:36AM (#22464741)
I doubt that's the case - for many years when I was a student I lived near equator and never went out. I never felt any impact or mind or body. I even tried some vitamin D3 supplement, smth like 2000IU but had no effects after few weeks, then I quit.

The biggest effect anything I had on me is Testosterone Enthante 250mg twice a week.

Also I wonder if taking 8,000 IU vitamin D can desentivize the system overtime

Re:Vitamin D supplementation to prevent acute respiratory tr... by hannob on Monday March 02, 2020 @08:19AM (#22464110)
> I can say from my own experience that the lack of vitamin D can have a significant impact on both mind and body.

No you can't. That's not how this works.

Re:Vitamin D supplementation to prevent acute respiratory tr... by leto_ii on Monday March 02, 2020 @08:26AM (#22464156)
> No you can't.

Yes I can :D

While my experience is obviously not definitive scientific proof it can still bring some value.

To give you a more simple example: when I broke my leg I went to the doctor's and put it in a cast. That helped me tremendously. Is that a well designed randomized controlled trial? No. Is it good advice to anybody with a broken leg? I would say so.

Re:Vitamin D supplementation to prevent acute respiratory tr... by lotsofpulp on Monday March 02, 2020 @08:35AM (#22464241)
A cast for a broken leg is not comparable to concluding cause and effect with a vitamin supplement. Vitamin supplement quality, absorption rate, measurement accuracy, etc are all difficult to pin down.
Re:Vitamin D supplementation to prevent acute respiratory tr... by leto_ii on Monday March 02, 2020 @08:45AM (#22464328)
There is science around this though. If you take a vitamin D blood test that shows low levels a doctor will prescribe a certain dose. Vitamin D is scientifically known to be important for humans, it's not just my opinion.
Re:Vitamin D supplementation to prevent acute respiratory tr... by lotsofpulp on Monday March 02, 2020 @09:50AM (#22464844)
That may be true, but it’s not the same as a broken leg and cast situation, and you need a well controlled randomized trial to say things about cause and effect for non observable phenomena such as the effects of vitamin supplements.
Re:Vitamin D supplementation to prevent acute respiratory tr... by coldtea on Monday March 02, 2020 @10:33AM (#22465207)
You seem confused as to how science works and what the parent said.

The setup you describe is for proving (with some statistical certainty) a certain causal relationship.

But the author doesn't want to prove it. It has already been proven experimentally. What he said is that he can tell us from his own experience. You don't need a controlled study for that.

I can tell from experience that a certain vitamin X deficiency can be very bad (e.g. because I had it, my doctor verified it, and I got very sick and had Y symptoms) without needing to prove that vitamin X causes Y if it's already proven.

Which is the same case with vitamin D. The parent didn't say he'll prove something novel, just that they'll verify it from experience.

Note that verification from experience is still very useful, even when something isn't proven. It's not as rigorous as science, but it's still very useful, can be life-saving, and it's how civilisation advanced for 1000s of years before we got "controlled studies". People already knew from experience not to eat X or Y plant for example (e.g. poisonous), without official studies and control groups.

People should still be required to be able to make deductions and learn from experience at this level before they offload everything to scientists.

Re:Vitamin D supplementation to prevent acute respiratory tr... by leto_ii on Monday March 02, 2020 @10:18AM (#22465062)
The point of the leg and cast example was to show that anecdotal evidence can be useful. I deliberately chose a clear and simple example. Indeed the case of vitamin D is more nuanced.
Re:Vitamin D supplementation to prevent acute respiratory tr... by 8bitsrule on Monday March 02, 2020 @08:09PM (#22470885)
A philosopher named Maxwell made an assertion in class one day.

Me: "You can't say that."

Philosopher: "I just did."

Remainder of students: laughter