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Re:Alternate Day Fasting Improves Physiological and Molecula... by kace91 on Tuesday August 27, 2019 @03:56PM (#20813819)
Are you fit? as in, do you lift weights or are active in sports that require strength?

I ask because I wonder about the effects of extended fasts on muscle loss/retention, a big problem cutting weight for some people is that they get rid of some muscle mass along with the calories they wanted to eliminate.

Re:Alternate Day Fasting Improves Physiological and Molecula... by jniedrauer on Tuesday August 27, 2019 @05:56PM (#20814831)
I can speak to this a bit. I practiced intermittent fasting (eating once per day) for nearly a decade, while maintaining a very low activity level. My resting metabolic rate dropped significantly during this time (down to about 1300 kcal/day).

About a year ago, I increased my activity level significantly (distance running, hiking, strength training, cycling) and quickly found that:

a) I wasn't recovering quickly enough

b) It was extremely difficult to take in enough calories for a day in a single meal

c) I had very low energy when in ketosis

Eventually I gave up and just started eating on a typical 3-4 meal a day schedule. My RMR steadily increased back to baseline, I got a lot more explosive energy, my body began responding much more rapidly to training, and my recovery speed improved significantly.

Personally I think that intermittent fasting is not a good idea if you are very physically active. That's just my opinion from my own experience.

Re:Alternate Day Fasting Improves Physiological and Molecula... by jodrellblank on Tuesday August 27, 2019 @06:06PM (#20814899)
There is a range of IF between one meal per day, and not doing it at all. Prof Sachin Panda’s research on mice shows effects of 12hrs/12hrs, 8hrs eat/16hrs fast, and fasting some days but not every day.

Did you experiment with any other patterns?

Re:Alternate Day Fasting Improves Physiological and Molecula... by heymijo on Tuesday August 27, 2019 @04:57PM (#20814346)
There is a recent US Military study that shows that under a severe caloric deficit and with increased energy expenditure that yes, you still preserve lean body mass. [0] Granted this was not fasting, but it's interesting nonetheless.

Don't be thrown off by the title. Yes, one group received testosterone, but even the placebo group that did not receive anabolic steroids, lost nearly 10 pounds of fat without losing any appreciable amount of lean body mass.

Dr. Peter Attia wrote about it in his newsletter this past week. [1]

Between my anecdotal experience of not feeling like I lose much lean body mass while fasting, this study above, and recent evidence from studies shown that "muscle memory", where a muscle can quickly regain any lost size it has had, is in fact real...I don't lose much sleep over losing muscle while fasting.

[0] https://www.sciencedirect.com/science/article/pii/S235239641... [1] https://peterattiamd.com/can-you-preserve-lean-body-mass-dur...

Re:Alternate Day Fasting Improves Physiological and Molecula... by dvt on Tuesday August 27, 2019 @04:01PM (#20813868)
I did for a few months this year, but I've been lazy over the summer. I'm 155lb, 6'0, so fairly skinny, maybe at around ~15% BF. I noticed that fasting doesn't help with BF at all unless I eat very clean and lift. I was at 170lb, around ~28% BF earlier this year and had to work my ass off to get my body fat percentage down.
Re:Alternate Day Fasting Improves Physiological and Molecula... by pmart123 on Tuesday August 27, 2019 @04:49PM (#20814283)
Interesting. I just started experimenting with a 16-8 fast, and I have noticed that it is hard to eat larger portions when you constrain the eating window to eight hours. Did you think it helped maintain your 15% BF?
Re:Alternate Day Fasting Improves Physiological and Molecula... by dvt on Tuesday August 27, 2019 @06:29PM (#20815092)
> Did you think it helped maintain your 15% BF?

Nope.

I stopped counting macros and started eating just whatever again at the beginning of the summer and I'm slowly gaining the fat back. Unfortunately, there are no shortcuts (at least for me).

Re:Alternate Day Fasting Improves Physiological and Molecula... by bradhoffman on Tuesday August 27, 2019 @04:16PM (#20814000)
Lifting specifically, or any sort of physical activity? I’ve been running and IF for the past month in order to cut my BF %. I was at about 16%, but I’d like to get down to 12%.
Re:Alternate Day Fasting Improves Physiological and Molecula... by mrosett on Tuesday August 27, 2019 @09:24PM (#20816067)
I've found that lifting is much better for weight loss than running/biking. I've gained weight while running 30-40 miles/week and typically lose weight while lifting (if I pay attention to my calories.) A lot of people say the same.

If you're focused on BF%, lifting is even more appealing since you'll be building muscle/reducing bf% even at a constant weight.

Re:Alternate Day Fasting Improves Physiological and Molecula... by dvt on Tuesday August 27, 2019 @04:21PM (#20814051)
Lifting; I did Stronglifts 5x5 3 times a week. Part of the reason I stopped is that it got kind of boring and I got absolutely sick of doing squats 3 times a week.

It sucked, it was hard (especially on a caloric deficit), but it worked.

Re:Alternate Day Fasting Improves Physiological and Molecula... by SketchySeaBeast on Tuesday August 27, 2019 @04:26PM (#20814090)
> I noticed that fasting doesn't help with BF at all unless I eat very clean and lift.

So what happens? You lose muscle and fat in the same ratio? Or do you keep the fat?

Re:Alternate Day Fasting Improves Physiological and Molecula... by alexbanks on Wednesday August 28, 2019 @01:29AM (#20817027)
I haven't seen any studies that imply that fasting increases or decreases metabolic rates, which would mean that most people probably won't implicitly gain or lose significant amounts of weight just by switching to intermittent fasting.

There are people that literally just start skipping breakfast while keeping lunch/dinner/snacking the same. This is both technically intermittent fasting but also a reduction in overall caloric consumption. These people sometimes attribute their newfound weightloss to IF, when really they just started skipping a calorically dense meal every day.

Re:Alternate Day Fasting Improves Physiological and Molecula... by dvt on Tuesday August 27, 2019 @06:26PM (#20815067)
I feel that my body kind of adjusts to the fasting and I just don't lose much of anything.
Re:Alternate Day Fasting Improves Physiological and Molecula... by SketchySeaBeast on Wednesday August 28, 2019 @09:29AM (#20819537)
That sounds to me like "I eat more to make up the calories when I'm not fasting".
Re:Alternate Day Fasting Improves Physiological and Molecula... by ulisesrmzroche on Wednesday August 28, 2019 @12:45PM (#20821481)
Fat first cus it’s easier to break down. Muscle afterward.
Re:Alternate Day Fasting Improves Physiological and Molecula... by SketchySeaBeast on Thursday August 29, 2019 @09:47AM (#20829427)
That's what I would assume, but they said the opposite.
Re:Alternate Day Fasting Improves Physiological and Molecula... by monkeyshelli on Wednesday August 28, 2019 @03:13AM (#20817587)
Around my 30s I was quite overweight ~310lbs/140kg. Had done some stronglifts 5x5 and then decide to incorporate Keto into the mix (later targeted keto + IF). In the course of few years went down to ~230lbs/105kg while my lifts all went up (e.q squats from around 375lbs/170kg --> 460/210kg). At least my personal "gut feeling" is that I gained some muscle mass (my priority was to drop weight/fat).

For the past year, as an experiment, I've eaten carbs "normally" while doing 4x week gym. Few things I've noticed. My gut doesn't feel as good as it did while keto/IF, when you are in Keto and eat a cup of oatmeal ~45min before gym and start lifting you have this insane focus for the heavy 1-3 reps, I can seem to tolerate more better quality volume now compared to while doing keto/IF. But the overall feeling I have outside of the gym while not being in Keto/IF is a bit "sad", so most likely I'll start doing Keto/IF again to feel better. It's funny how insanely sweet strawberries taste while in Keto, and I kinda miss that feeling.

Re:Alternate Day Fasting Improves Physiological and Molecula... by pizza234 on Tuesday August 27, 2019 @04:26PM (#20814095)
I'm personally very skeptical [as well]. I notice that almost nobody that recounts their fasting experience ever mentions sport.

I personally found very hard already to progress on weightlifting during diet cycles, as I need to cut on volume significantly; can't imagine to do that while fasting, unless fasting would "flip a switch" in how the (my) body works, which I doubt.

Re:Alternate Day Fasting Improves Physiological and Molecula... by rsync on Tuesday August 27, 2019 @04:42PM (#20814236)
"I'm personally very skeptical [as well]. I notice that almost nobody that recounts their fasting experience ever mentions sport."

Allow me to step right up.

First, as you might expect, aerobic and endurance exercise benefits greatly from being in a fasted (16-24 hr) state. You're light, quick and your body is devoting zero blood flow (and other resources) to digestion. I suspect you're not surprised by this.

Second, I do a 1.5 hour heavy leg workout which includes squats, deadlifts and other assorted "big" movements with weight that is significant, compared to my body weight. No issues at all. I wouldn't do this on a 24 hour fast, but it is my regular habit to do this workout while in a 16-18 hour fasted state and in general I have very slightly better results than if I had eaten recently. Again, the issue is the amount of blood flow (and other resources) your body is putting into digestion.

Finally, while it is easy and enjoyable to do my BJJ workouts in a fasted state, I cannot, then, do several rounds of sparring at the end without more recent calories. Or rather, I can but I after round one or two I am running out of gas.

YMMV. You should just try it. It costs nothing.

Re:Alternate Day Fasting Improves Physiological and Molecula... by CamperBob2 on Tuesday August 27, 2019 @04:59PM (#20814364)
First, as you might expect, aerobic and endurance exercise benefits greatly from being in a fasted (16-24 hr) state

If that's true, why isn't it a universal practice in amateur and professional athletic competition?

(Or, for that matter, why isn't it banned?)

Re:Alternate Day Fasting Improves Physiological and Molecula... by argyleaf on Tuesday August 27, 2019 @05:39PM (#20814667)
I can't speak to endurance (I got into IF after my endurance-athlete days) but I know that body weight-based athletes do this to perform better. My experience is specific to rock climbing.

When you are right at the edge of your abilities being just a couple pounds lighter can feel like a world of difference (people hone down their rack to precisely what they need for a route, nothing more), especially on sport and boulder problems. My anecdata points to it being great for the project/performative aspects of the sport but as a tool for consistent progression/improvement, I am less confident in stating anything.

Re:Alternate Day Fasting Improves Physiological and Molecula... by zbtaylor1 on Tuesday August 27, 2019 @08:43PM (#20815841)
> First, as you might expect, aerobic and endurance exercise benefits greatly from being in a fasted (16-24 hr) state. You're light, quick and your body is devoting zero blood flow (and other resources) to digestion.

I'd say it depends greatly on the effort and the individual. Long, slow distance for someone who is accustomed to training fasted? Fat stores will suffice as an energy source.

But add in some intensity and that's gonna be rough without much glycogen in the tank - which will be the case if you've been fasting for the past 16-24 hours.

Re:Alternate Day Fasting Improves Physiological and Molecula... by l_t on Tuesday August 27, 2019 @05:14PM (#20814456)
I've experimented with fasting and weightlifting and I want to share some thoughts.

First, fasting does not require that your overall calorie intake is reduced. If your cut-goal is 2000kcal per day, you can fast in the morning and eat all 2000kcal in the afternoon. Ultimately, I find this is actually an easier and less hunger-inducing way to each your cutting goals.

Second, you're right. Doing weightlifting while fasted is hard. It's better to coordinate your gym schedule with your eating schedule so that you can eat -- I like a simple protein shake -- before and after the gym.

Third, I'm seeing a lot of folks talking about intermittent fasting ("IF") and day-long fasting in the same breath. I think IF is great for weightlifters on a cut diet. But I think day-long or multi-day fasts are different and should only be done occasionally (weekly being the most frequent) if you are trying to progress with weightlifting. YMMV.

Re:Alternate Day Fasting Improves Physiological and Molecula... by gardner_alphero on Tuesday August 27, 2019 @08:58PM (#20815943)
There is some evidence that appears to support the idea that there is a difference between calorie restriction and complete fasting. You sound like the type of person that likes to dig into the studies. Dr. Jason Fung does a good job of writing in plain English while linked to and referring to the supporting studies: https://www.dietdoctor.com/fasting-muscle-mass

The studies may not have been conducted among athletes so, testing your own body's response (by measuring lean body mass before and after a fast) seems like the best way forward.

I have read that people on keto diets or fasting have less "explosive" energy for workouts. I am not concerned that my body is going to cannibalise my biceps if I don't eat for a day or two. There is a lot more energy kicking around that is less important.

For me, it's worth it for the HGH boost: https://www.dietdoctor.com/fasting-and-growth-hormone

Re:Alternate Day Fasting Improves Physiological and Molecula... by kdbg on Tuesday August 27, 2019 @07:25PM (#20815412)
I think for that you might want to research Protein sparing modified fasting, https://en.m.wikipedia.org/wiki/Protein-sparing_modified_fas...

Gist of it is you still cut significant calories only eating like 500-800 a day in mostly low fat protien rich foods. Targeting only enough protien to avoid muscle wasting.

While I'm no doctor or nutritionist, my understanding is that it's for that case, you want some of the benefits of fasting like going into ketosis while maintaining lean mass.

Unfortunately I'm on my phone only this week so I can't try and find any studies about it, but I came across it first in connection with type 2 Diabetes. So you might have some luck googling those topics for more info.

Re:Alternate Day Fasting Improves Physiological and Molecula... by appleiigs on Wednesday August 28, 2019 @12:32AM (#20816801)
In the book Obesity Code, it says that during fasting human growth hormone levels increase. This maintains muscle mass.