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Re:Founder of GitLab battles cancer by founding companies by melling on Saturday March 28, 2026 @03:09PM (#47557370)
Why can’t we just ask our governments to spend more on research? Want some rich person to donate $100 billion on cancer research?

The US government and European governments could find that amount of money every year.

Re:Founder of GitLab battles cancer by founding companies by georgemcbay on Saturday March 28, 2026 @04:18PM (#47557826)
> The US government [...] could find that amount of money every year.

Sorry, that money is already earmarked for killing Iranian school girls and funding a gestapo to terrorize immigrants and American citizens. Ain't got enough left over after we cover those essentials.

Re:Founder of GitLab battles cancer by founding companies by PowerElectronix on Saturday March 28, 2026 @04:09PM (#47557778)
We are not the bosses of the people in the government, so asking does very little.
Re:Founder of GitLab battles cancer by founding companies by declan_roberts on Saturday March 28, 2026 @03:18PM (#47557422)
The United States and world spend huge amounts of money on this, not even to mention the enormous amounts of private research.

The takeaway here is getting money into the hands of smarter and more motivated people.

Re:Founder of GitLab battles cancer by founding companies by light_hue_1 on Saturday March 28, 2026 @03:31PM (#47557524)
No we absolutely don't. The US hardly spends anything on research.

The entire yearly budget for the National Cancer Institute is $7 billion dollars. To put this in perspective, that's 3 days of funding the DoD. For cancer. That kills well over half a million Americans per year.

The takeaway is that we should invest in research rather than letting people die.

Re:Founder of GitLab battles cancer by founding companies by miki123211 on Saturday March 28, 2026 @04:59PM (#47558060)
It's a problem of incentives.

Governments have a limited (although large) budget, and no incentive to spend it well[1]. You don't get promoted as a government administrator if you approve a Nobel-prize-winning grannt.

If you don't get rewarded for good work but may get punished for taking risks, you optimize for risk minimization, even if this means a lot of potentially-good work not getting done.

Nobody blames the FDA when millions of people die from the-medicine-hasn't-been-invented-yet-itis, everybody blames the FDA when ten or so people die from a side effect nobody saw. This impacts FDA policy.

This person has the best incentive there is in the world, the incentive to live. He didn't care whether the people getting his money correctly filled form 437-F, or whether they have the relevant paperwork that verifies their legitimacy in a way which can be described by legal rules.

[1] Incidentally, finance has (had?) the opposite problem. If your bonus is calculated as min(0, percentage * profit_generated), you will maximize risk, optimizing for bets that give you great returns most of the time, but wipe you out completely some of the time, as your losses are clamped to 0.

Re:Founder of GitLab battles cancer by founding companies by kelnos on Saturday March 28, 2026 @05:40PM (#47558352)
> If your bonus is calculated as min(0, percentage profit_generated)*

I assume you meant `max(...)`? Otherwise you will at best get zero dollars in bonus, and at worst owe your employer money. ;)

(I get min/max backward all the time too.)

Re:Founder of GitLab battles cancer by founding companies by BobbyJo on Saturday March 28, 2026 @03:22PM (#47557454)
You can't compare the output of small teams driven by a fanatic with a single output metric with government funded research. NIH invests about 40 billion in research a year in the US as it is I believe.
Re:Founder of GitLab battles cancer by founding companies by melling on Saturday March 28, 2026 @03:27PM (#47557489)
I asked Gemini AI and it says the NIH spent $7.3 billion last year.

Would it be a big deal to double that?

Re:Founder of GitLab battles cancer by founding companies by BobbyJo on Saturday April 04, 2026 @03:04AM (#47636626)
Do we just keep increasing spending until the marginal value of further spending goes to zero so long as the next incremental dollar "isn't a big deal?"
Re:Founder of GitLab battles cancer by founding companies by VectorLock on Saturday March 28, 2026 @03:24PM (#47557475)
In another timeline they're doing a "Cancer Moonshot" right now.
Re:Founder of GitLab battles cancer by founding companies by inglor_cz on Sunday March 29, 2026 @05:22AM (#47561601)
It is a bit simplistic to assume that more money translates into better research outcomes.

Alzheimer's is a warning tale. Lots of money flowed into research of this condition, and was mostly wasted on a flawed hypothesis supported by scientific VIPs who had a face to lose in case it proved incorrect.

We don't necessarily need more money in research, but smarter ways of spending it. The current grant system rewards established players and reliable production of mediocre (or even fraudulent) papers over honest failure and actual innovation too much.