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Re:Do Viruses Trigger Alzheimer's? by anovikov on Sunday March 23, 2025 @09:07AM (#43452641)
The frequently cited "stress" thing of modern lives is just eyebrows-raising. Do anyone actually believe that lives of people 100 or 200 years ago have been less stressful?
Re:Do Viruses Trigger Alzheimer's? by vjk800 on Sunday March 23, 2025 @10:15AM (#43453077)
Physical activity gives an outlet to stress, and people used to get way more of it. Stress and physical effort are supposed to go hand-in-hand; you feel stressed, which gives you a boost of adrenaline, which you need to physically fight back whatever caused the stress. When the physical component is missing, the stress just lingers and wreaks havoc on your body.
Re:Do Viruses Trigger Alzheimer's? by OutOfHere on Monday March 24, 2025 @01:00AM (#43457879)
Also, sunlight exposure (with limited UV) went hand in hand. Now we have neither.
Re:Do Viruses Trigger Alzheimer's? by butlike on Monday March 24, 2025 @12:01PM (#43462547)
Careful. Exercise also causes a stress response in-and-of itself.
Re:Do Viruses Trigger Alzheimer's? by phkahler on Sunday March 23, 2025 @09:55AM (#43452961)
Work is not the same as stress. People today (especially near the bottom of the ladder) are not in control of their own destiny like they used to be. It's a different kind of stress.
Re:Do Viruses Trigger Alzheimer's? by victorbjorklund on Sunday March 23, 2025 @10:17AM (#43453097)
Slaves were more on control of their own destinys than someone working an entry job today?
Re:Do Viruses Trigger Alzheimer's? by phkahler on Monday March 24, 2025 @11:08AM (#43461952)
I was thinking more about farmers.
Re:Do Viruses Trigger Alzheimer's? by anovikov on Sunday March 23, 2025 @10:24AM (#43453147)
And they used to be more in control? Epidemics wiping out whole families? Gulags, concentration camps? Religious violence? Persistent threat of starvation death that was just the norm of life? One year of crop failures, and your kids are dead. Two years, and you are dead yourself. And it doesn't depend on you at all, just bad luck (if there was too much luck - like a generation without crop failures - population doubled, then just one year of crop failures meant you were dead). And yeah, the Church that keeps telling people that they were all sinners and will burn in hell, very comforting. Tell me about "control of one's own destiny".
Re:Do Viruses Trigger Alzheimer's? by cosmic_cheese on Sunday March 23, 2025 @12:20PM (#43453907)
I think there’s something to this. Life in those times was difficult and stressful, yes, but most hardships then were entirely beyond any individual’s control. To a large extent, good times and bad times would come and go regardless of what you did.

Contrast this to the modern day where more often than not, hardships are attributed to personal failings (“You should’ve worked harder if you didn’t want to be stuck working abusive under-compensated jobs!”) and people perpetually teeter on the edge of a knife suspended over a bottomless pit. If anything goes wrong, it’s treated as nobody’s fault but your own, regardless of the reality of the situation. It’s almost a type of psychological torture.

Re:Do Viruses Trigger Alzheimer's? by theoreticalmal on Sunday March 23, 2025 @09:23AM (#43452766)
I think the idea is that the cells are stressed due to inflammation due to diet, rather than psychological feelings of stress
Re:Do Viruses Trigger Alzheimer's? by anovikov on Sunday March 23, 2025 @10:28AM (#43453168)
Average "healthy" body temperature is down more than half degree exactly because of reduction in inflammation. People used to have very unsanitary lives and were fighting infections nonstop. 37.0C was the "normal" body temperature when the "norm" was first discovered in the early XIX century, now it's considered to be a sickness already.
Re:Do Viruses Trigger Alzheimer's? by xeromal on Sunday March 23, 2025 @11:45AM (#43453681)
I'm not an expert but maybe keeping the immuno-army busy with constant infections keeps it from going bored and attacking itself
Re:Do Viruses Trigger Alzheimer's? by serf on Sunday March 23, 2025 @02:48PM (#43454879)
also not-an-expert opinion, but an average higher body temperature would reduce immune system workload by virtue of killing a lot of stuff dead via inhospitable environment before an immune reaction could ever muster..
Re:Do Viruses Trigger Alzheimer's? by SamPatt on Sunday March 23, 2025 @09:37PM (#43457237)
Fascinating claim, where did you hear this?
Re:Do Viruses Trigger Alzheimer's? by anovikov on Monday March 24, 2025 @02:19AM (#43458139)
Re:Do Viruses Trigger Alzheimer's? by ta12653421 on Sunday March 23, 2025 @10:17AM (#43453101)
Re:Do Viruses Trigger Alzheimer's? by giantg2 on Sunday March 23, 2025 @09:14AM (#43452684)
It's possible they had better support systems due to larger families, church being more prominent, etc.
Re:Do Viruses Trigger Alzheimer's? by MrMcCall on Sunday March 23, 2025 @11:07AM (#43453413)
Any form of positive community is helpful, religous or not. Just having caring neighbors is a boon to well-being.