You might like the book Transformer: The Deep Chemistry of Life and Death by Nick Lane. (anyone enjoying this comment section would) but specifically he presents some really cool interesting ideas related to this and metabolism

A joke from one of the greatest Spider-Man movies of all time, so you get a pass

I have that thought quite often, both for cells and for aggregate things like countries or religions.

Most recently I found myself framing zoonotic diseases (e.g. Lyme, Covid, Malaria) as ecosystem-level weapons against habitat loss i.e. as a manufactured reason to keep humans away.

As an expert myself, I say both of you deserve the Ig Nobel.

> I have that thought quite often, both for cells and for aggregate things like countries or religions.

You both might find this interesting :)

Information Closure Theory of Consciousness (2020) https://www.researchgate.net/publication/342956066_Informati...

> However, only information processed at specific scales of coarse-graining appears to be available for conscious awareness. We do not have direct experience of information available at the scale of individual neurons, which is noisy and highly stochastic. Neither do we have experience of more macro-scale interactions, such as interpersonal communications. Neurophysiological evidence suggests that conscious experiences co-vary with information encoded in coarse-grained neural states such as the firing pattern of a population of neurons. In this article, we introduce a new informational theory of consciousness: Information Closure Theory of Consciousness (ICT)

Still watching the seminars, but this is the clearest text summary I've found online so far: https://www.reddit.com/r/MachineLearning/comments/dco3t1/com...

Isn’t another explanation that they travel in such large amounts they will eventually interact with the right system due to chemical interactions? That is the right proteins will activate the right channels eventually when you have hundreds of thousands of attempts? I don’t think they are conscious in the sense they are driving along a road and know where to turn. It’s all chemical signaling and statistics.

I travel in such large amounts that I eventually interact with the right systems. I have some neat meta processes for changing direction and re-orienting myself on a couple of important goals for my existence. It’s not really conscious when I change direction, it’s just kinda natural. I end up being like “whoa that was a big change.”

I can’t remember where I’ve seen it but there’s some interesting work done Michael Levin in this space. Something along the lines of how cells alone can have a goal but within a group exhibit different goals. This can go from cell to tissue to organ, all the way up to society. I’m not a biologist so I’m butchering his ideas, just writing this if anyone finds it interesting to look him up.

> I find myself wondering if there is a primitive consciousness on the cellular level

Has anyone seriously tried tackling this with fiction?

Possibly, although I always thought Osmosis Jones was a documentary.

Right cells of a single individual co-operate, why should sperm-cells be any different.

Yes and no. What's different about sperm-cells is you would expect an "every man for himself" behavior. Instead, they recognize (?) there might be other competition, other sperm donors if you will, and they therefore co-operate so one of their own wins.

Does this mean monogamy is unnatural? Or at least at one point was not the norm? And still isn't? As why continue to optimize for co-operation?

One hypothesis is that the shape of the glans penis serves to push rival sperm out of the way and behind the glans to be scooped out of the vagina.

I wouldn't call monogamy unnatural. But it may be a more recent invention for humans. We still aren't sure how long it's been the norm.

It's possible that humans used to rape more often. It's also possible that humans practiced forms of polygamy. Either way, cooperative sperm makes sense. It's one of those things where a simple mutation would provide a clear benefit over the competition.

> What's different about sperm-cells is you would expect an "every man for himself"

You could expect that if each of them were an individual. Are they? One could say that all sperm-cells in a single ejaculation are part of the same single man.

Therefore the principle still holds, but it could be re-phrased as:

"Every sperm-cell for the donor-man"

All the other cells have the same DNA[1], they are like identical twins. It's like an army of clones.

Each sperm has a different DNA, they are like siblings. It's expected some cooperatio, but also some treason and backstabing.

[1] Ignoring some interesting cases.

> It's expected some cooperatio, but also some treason and backstabing.

That wouldn't be surprising, but I don't know if that is true.

I wouldn't not be surprised either way. A species survives not because its individuals do but because its genes do. Taking all available genes and spreading a subset of them amongst sperm-cells randomly is an interesting strategy.

It might be even optimal because the traits of a sperm-cell that make it survive during conception are not the same traits that help an individual thrive outside the womb.

If the 'fastest swimming' sperm-cell would always win, it would mean that in future generations faster and faster sperm-cells would win, but that would not necessarily help the survival of the species.

> I find myself wondering if there is a primitive consciousness on the cellular level

That seems to be obviously true to me. The alternative would be that consciousness simply appears at some point out of literally nowhere because there would be no lower levels from which it emerges.

Sounds like this

* pushes the problem one level down ("why are cells conscious?")

* adds the problem of explaining how consciousness of a person relates to consciousness of its cells.

What would this model help explain?

Right, but it seems that both problems are easier than "it just emerges out of nothing".

Cells consciousness would be a much, much simpler sort of consciousness, something any "object" that somehow is capable of searching for food and avoiding "danger" should possess.

Higher level things emerging from similar, but lower level things is not a mystery, it's something expected (like ant colonies).

I'm vaguely for pan-psychism as in, it sounds good but I haven't thought about it for even 5 minutes. But I'm more interested in the version where all matter has some kind of proto-consciousness. Still, no idea how it's suposed to work in detail: how can it make a difference whether a particle is part of an information-processing system? There is an infinitude of mappings between physical systems and mathematical functions (I'm probably plagiarizing a half-forgotten version of this https://joe-antognini.github.io/ml/consciousness )

I has to go all the way down by that logic, right?

> Conversely, when you look at the dynamics of large groups, organizations, and corporate entities (institutions as well as business, up to whole nations), it's hard not to see them as organisms in their own right that have a sort of meta-consciousness independent of their component humans.

That's actually a thing, or at least there's a name for it:

https://en.wikipedia.org/wiki/Egregore

This struck me like a Medicare benefits review commercial. I think those are also a bit more substantive. ;)

I don’t think there’s a consciousness but I think most biologist would agree there must be some kind of “awareness” within cells and imo likely that awareness is the basis for what we’d call consciousness.