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Re:Polio Is on the Brink of Eradication by hilbert42 on Thursday November 23, 2023 @08:10AM (#38392360)
As someone who lived through the polio epidemic during my childhood and having seen kids die of the disease or end up in iron lungs or having to wear calipers for life, I can only say hallelujah I hope this announcement about its likely eradication ends up being true.
Re:Polio Is on the Brink of Eradication by orra on Thursday November 23, 2023 @11:19AM (#38394395)
Indeed, it'd be wonderful to see polio eradicated. Eradication has been a decades long program; they originally aimed to do it by the year 2000, then ?, then 2018.

Even if the last stage of eradication is stubbornly slow, we have obviously been quite successful at limiting the number of cases.

Re:Polio Is on the Brink of Eradication by alfredpawney on Thursday November 23, 2023 @02:46PM (#38396719)
Honestly never thought i’d see the day.
Re:Polio Is on the Brink of Eradication by smegger001 on Thursday November 23, 2023 @03:15PM (#38397037)
Well it didn't help when the CIA got caught posing as health workers giving out polio vaccination in Pakistan.
Re:Polio Is on the Brink of Eradication by codezero on Thursday November 23, 2023 @04:06PM (#38397544)
The scheme was for hepatitis vaccinations. The article linked below just mentions that only health workers giving polio vaccines had previously been able to access the compound.
Re:Polio Is on the Brink of Eradication by LordShredda on Thursday November 23, 2023 @03:46PM (#38397338)
https://www.theguardian.com/world/2011/jul/11/cia-fake-vacci...

The taliban started attacking polio vaccine workers and the UN suspended operations. Polio exists in Pakistan, Afghanistan, and Nigeria

Re:Polio Is on the Brink of Eradication by jryle70 on Thursday November 23, 2023 @09:20PM (#38400066)
Why that certainly didn't help, the main reason has been misconception and religious belief:

According to a study conducted in Khyber Pakhtunkhwa, Pakistan, respondents misconceived the vaccine to be capable of causing harm to the immune system (93%), triggering adverse reactions 97.5%, to be against their social and moral values (95%), and to be not as good as traditional methods for treating children 98.5%

https://www.emro.who.int/emhj-volume-28-2022/volume-28-issue...

Re:Polio Is on the Brink of Eradication by honksillet on Thursday November 23, 2023 @10:50PM (#38400491)
Pakistani parents have good reason to not trust anything administered by a needle. 700 children recently contracted HIV. https://www.washingtonpost.com/world/asia_pacific/hundreds-o...
Re:Polio Is on the Brink of Eradication by freshpots on Thursday November 23, 2023 @11:09PM (#38400573)
"Pakistani parents have good reason to not trust anything administered by a needle. 700 children recently contracted HIV."

Is not a good rationale for making a decision. Parents, indeed anyone, shouldn't be worried about anything administered by a needle unless proper protocols are not followed, and they always should.

Re:Polio Is on the Brink of Eradication by austhrow743 on Thursday November 23, 2023 @11:23PM (#38400617)
They should pretend proper protocols are followed because proper protocols should be followed?
Re:Polio Is on the Brink of Eradication by ceejayoz on Thursday November 23, 2023 @11:40PM (#38400688)
That's like saying the cure for cancer is not getting cancer.
Re:Polio Is on the Brink of Eradication by polynomial on Friday November 24, 2023 @12:32AM (#38400898)
works every time.
Re:Polio Is on the Brink of Eradication by TomK32 on Friday November 24, 2023 @01:31AM (#38401161)
Also works against speeding tickets. But don't tell anyone
Re:Polio Is on the Brink of Eradication by K0balt on Friday November 24, 2023 @05:53AM (#38402631)
The outbreak of HIV in Pakistan is because of needle reuse.
Re:Polio Is on the Brink of Eradication by hilbert42 on Monday November 27, 2023 @02:23AM (#38429181)
I've mentioned this previously on HN. In the early 1960s when I was vaccinated at school we were done with a common needle that was used multiple times.

Nowadays it's a horrific notion and should never be done but back then the horrors of polio were so real and frightening that doing multiple vaccinations with one needle was of secondary importance (or so it seems). I've often wondered since how many cases of polio and hepatitis were actually spread back then by using a common needle (I've never understood why even back then doctors weren't concerned about this).

BTW, as I've mentioned previously, we kids were lined in the school's assembly hall in two long lines of over 100 that extended out the doors into the schoolyard—one line for boys and one for girls—and vaccinated immediately one after another. After every dozen or so kids the needle was changed.

It quickly got around that a new needle didn't hurt as much as a well-used one and we kids started jostling for positions in the line. We watched and counted how often the needle was changed then count our position in the line, we then we'd pay pennies to buy an optimal positions in the line (be first after the needle was changed). That being first was less risky never entered our minds.

At no time were we ever told about the dangers of sharing needles. As far as I am aware none of us got ill from that experience.

Incidentally, the whole school of about 1100 kids was vaccinated in about an hour and half—between the morning tea break and lunchtime. Compare that with the slow rigmarole of vaccination campaigns of today.

Re:Polio Is on the Brink of Eradication by unmole on Friday November 24, 2023 @04:55AM (#38402220)
Polio vaccine can be administered orally.
Re:Polio Is on the Brink of Eradication by pyuser583 on Thursday November 23, 2023 @11:51PM (#38400740)
Yeah there was an X-Files episode where the CIA gathered DNA via polio vaccines.

Which means someone at the CIA said, “Hey that thing that happened in the X-Files, let’s do that but for real!”

Re:Polio Is on the Brink of Eradication by smegger001 on Friday November 24, 2023 @06:41AM (#38402949)
It doesn't inspire confidence when your spy agencies start stealing ideas from the villain spies who got caught in a TV show from the 90s
Re:Polio Is on the Brink of Eradication by slavik81 on Saturday November 25, 2023 @01:14AM (#38411630)
Wasn't it the Smallpox Eradication Program?
Re:Polio Is on the Brink of Eradication by pyuser583 on Saturday November 25, 2023 @11:49AM (#38414609)
That may have been it!

Spoiler:

It was the one where Mulder finds his sister’s record, then tears off the name to see his own underneath.

I doesn’t really matter though. The real world CIA vaccines were against Hepatitis B.

Re:Polio Is on the Brink of Eradication by gumby on Thursday November 23, 2023 @01:18PM (#38395752)
FDR caught polio in his 20s and was wheelchair bound after that.

Mitch McConnell had a mild case of polio as a child and once you know that you can see the resulting trivial impairment in his gait and facial expressions. However his utterly evil attitude and actions have nothing to do with polio.

Re:Polio Is on the Brink of Eradication by shiroiuma on Friday November 24, 2023 @05:39AM (#38402524)
>However his utterly evil attitude and actions have nothing to do with polio.

You don't know that. Without looking into many alternate universes where he did not have polio, there's no way to know how having polio affected his mind, either biochemically or simply by affecting his experiences during his formative years in childhood. Remember the butterfly that causes a hurricane.

Re:Polio Is on the Brink of Eradication by gumby on Friday November 24, 2023 @02:34PM (#38407333)
A shame a rigorous, controlled A/B test wouldn't be ethical, much less possible. What if it turned out to be possible to vaccinate against becoming a jerk?
Re:Polio Is on the Brink of Eradication by shiroiuma on Sunday November 26, 2023 @11:50PM (#38428190)
The problem is that there's infinite ways that someone having a disease like polio could change their actions and therefore the future, and not all outcomes are actually worse. Perhaps having polio makes some people into jerks, and for others it somehow makes them better. Perhaps having polio effectively neutralizes some people who would have caused great harm if they had stayed healthy. Imagine if Hitler had contracted polio and was stuck in an iron lung for most of his life: history would be very different. Perhaps one of the people who did get stuck in an iron lung would have been another Hitler. The possibilities are endless.
Re:Polio Is on the Brink of Eradication by Modified3019 on Thursday November 23, 2023 @05:14PM (#38398194)
I wasn’t familiar with the term calipers outside of the measuring tool. For anyone else wondering, it refers to the leg braces used by those who have polio induced nerve damage and subsequent muscle weakness (poliomyelitis).
Re:Polio Is on the Brink of Eradication by shiroiuma on Friday November 24, 2023 @05:37AM (#38402497)
>I wasn’t familiar with the term calipers outside of the measuring tool.

It also refers to the part in disc brakes which holds the brake pads and squeezes them together onto the rotor.

Re:Polio Is on the Brink of Eradication by Clubber on Thursday November 23, 2023 @10:43PM (#38400466)
Jonas Salk is one of my personal heroes. Probably the best and most selfless human I can think of. A true credit of and benefit to humanity. A stark contrast with most of today's innovators.

https://en.wikipedia.org/wiki/Jonas_Salk

Salk was immediately hailed as a "miracle worker" when the vaccine's success was first made public in April 1955, and chose to not patent the vaccine or seek any profit from it in order to maximize its global distribution.

Re:Polio Is on the Brink of Eradication by pclmulqdq on Thursday November 23, 2023 @10:55PM (#38400516)
Salk tried and failed to patent the polio vaccine because it was rejected by the USPTO as not being novel. He didn't choose not to patent the vaccine out of the goodness of his heart.
Re:Polio Is on the Brink of Eradication by kaliumex on Friday November 24, 2023 @12:31AM (#38400895)
The patent was pursued by National Foundation for Infantile Paralysis who funded Salk's research.

Salk himself wasn't much in favour of a patent, stating that his techniques weren’t novel and the work was built upon the research of others.

https://www.latimes.com/business/hiltzik/la-fi-mh-polio-vacc...

Re:Polio Is on the Brink of Eradication by pclmulqdq on Friday November 24, 2023 @08:22AM (#38403705)
All of those famous public statements by Salk occurred after his work was determined to be unpatentable by the funding agency. We don't really know what happened behind closed doors other than the normal university/nonprofit research process, which involves a lot of profiteering. The same thing happened with Sabin before that vaccine was also released without a patent (Sabin would have been a Soviet/Russian patent, so it's a slightly different system).

The famous "could you patent the sun" quote was about obviousness, not about anything else.

Re:Polio Is on the Brink of Eradication by Aloha on Thursday November 23, 2023 @10:58PM (#38400529)
This runs counter to every source I've read - do you have a source for it?
Re:Polio Is on the Brink of Eradication by pclmulqdq on Thursday November 23, 2023 @10:53PM (#38400503)
There's been a lot of progress, but sadly the GPEI is still at least a decade from eradication if they are agressive... and already starting to slow down. They really need one last push, and it's becoming clear that it's not going to come from Gates or the WHO.

Dealing with vaccine-derived polio is going to be the big issue for the next decade, but projections suggest that type 1 polio will go out of control if OPV cessation happens on the desired timeline and the status quo is kept up until then.

If Ken Griffin or Jim Simons (or any hedge fund guy) wants some extra karma or has beef with Bill Gates, this is probably an $X billion project in total, but it seems to need someone who can out-asshole Afghan warlords and is willing to crack a few skulls to get it done.

Re:Polio Is on the Brink of Eradication by riffraff on Friday November 24, 2023 @03:17AM (#38401679)
> it's becoming clear that it's not going to come from Gates or the WHO.

Wasn't the gates foundation a big promoter of this? I thought it was one of their main focuses.

Re:Polio Is on the Brink of Eradication by pclmulqdq on Friday November 24, 2023 @09:22AM (#38404231)
Publicly, the Gates foundation wants to take credit for polio eradication, but they never seem to want to actually spend the money on the things that are required for polio eradication. If you look at the modeling results, Gates and the WHO manage to do less than the minimum required to have a decent chance of "turning the corner," while also doing a lot of fun science projects like making a new version of OPV.

Gates himself moves between a lot of different "current things" - it was polio 15 years ago, then it became malaria, and now it seems to be the climate (with a brief stopover on COVID).

Re:Polio Is on the Brink of Eradication by jasonwatkinspdx on Friday November 24, 2023 @02:27AM (#38401418)
When I was a kid a friend of the family was a polio survivor. It definitely made an impression on me. Polio is truly horrific. Eradicating it will truly be one of humanity's great achievements.
Re:Polio Is on the Brink of Eradication by ridgeguy on Friday November 24, 2023 @03:04AM (#38401614)
We may be of a similar age cohort.

I vividly recall my parents' mounting anxiety as three of our neighborhood kids were stricken and put in iron lungs. One died (age 4), two recovered (ages 5 & 6) after around 6 months in hospital. I've kept track of one - she's 74. In her 50s, she developed muscle degeneration as part of post-polio syndrome. Wrecked her ability to live independently.

I got both the Salk and the later Sabin vaccine. That took a huge weight from my parents' spirit, improved our family dynamics.

I'll track this story. I deeply hope for polio to follow smallpox into oblivion.