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Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by code_runner on Tuesday January 03, 2023 @10:30AM (#34232637)
“One of the best things for society” is a very very bold claim. For the uninformed like myself how would psychedelic therapy be THIS beneficial?
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by chaps on Tuesday January 03, 2023 @10:51AM (#34232990)
Just one example:

https://www.nbcnews.com/health/mental-health/psilocybin-mush...

  "More than 80% of those who were given the psychedelic treatment had drastically reduced their drinking eight months after the study started, compared to just over 50% in the antihistamine control group, according to results published Wednesday in JAMA Psychiatry. At the end of the trial, half of those who received psilocybin had quit drinking altogether, compared to about one-quarter of those who were given the antihistamine."
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by rhacker on Tuesday January 03, 2023 @11:13AM (#34233333)
Sounds like anti-histamines are a good mechanism to stop drinking!
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by chaps on Tuesday January 03, 2023 @11:47AM (#34233903)
No need for the silly reductionist snark there, friend. They were also given 12 psychotherapy sessions during the 8mo study.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by gausswho on Tuesday January 03, 2023 @10:56AM (#34233072)
that the placebo led to abstinence in 25% of cases makes me concerned about a selection bias in the pool
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by SeanAnderson on Tuesday January 03, 2023 @11:02AM (#34233154)
What % would you expect to be affected by the placebo?
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by chairmanwow1 on Tuesday January 03, 2023 @11:21AM (#34233466)
I think most adults are in a steady state for their habitual behaviors around diet / exercise / drinking / drugs. Would be surprised by anything larger than 10% change in control tbh
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by TylerE on Tuesday January 03, 2023 @11:28AM (#34233575)
FTA: "helped people with alcohol use disorder reduce drinking for at least eight months after their first treatments, results from the largest clinical trial of its kind show."

This isn't a genpop study.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by TylerE on Tuesday January 03, 2023 @01:30PM (#34235640)
Also, both prongs were given psychotherapy, also.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by boomboomsubban on Tuesday January 03, 2023 @11:10AM (#34233282)
Is it that hard to imagine twelve psychotherapy sessions convincing someone to quit drinking for eight months?
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by more_corn on Thursday January 05, 2023 @05:48PM (#34268066)
Have you ever met an alcoholic?
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by boomboomsubban on Sunday January 08, 2023 @01:07PM (#34301429)
Yes. I've also met former alcoholics, and people who quit for a while then started drinking again. Twelve weeks of therapy leading to eight months of sobriety for 25% of people does not seem surprising.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by say_it_as_it_is on Tuesday January 03, 2023 @10:54AM (#34233042)
It can help treat a range of issues: addictions, various traumas, depression, fears and anxieties. Also, it can be very dangerous for anyone with genetic predispositions to a range of mental health issues, such as bipolarism and schizophrenia, so anyone who is dealing with mental health issues ought to know their family history or get personally tested for the genetic markers.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by meowmeowmoo on Tuesday January 03, 2023 @11:04AM (#34233177)
They have genetic markers for all these? Any good test recommendations?
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by marmadukester39 on Tuesday January 03, 2023 @03:28PM (#34237526)
Very interested to know this
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by paisleypepper on Tuesday January 03, 2023 @02:46PM (#34236954)
This is very serious.

My brother's schizophrenia started while I sat with him on the grass trying to comfort him after he had taken mushrooms.

This led to moment after moment of things that are difficult to for me to talk about. My family spent 3 Christmases at the state hospital to be with him. Thanks to the help he was able to get at the hospital and through continued care, he's now able to live with my parents.

Please be wise.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by hericium on Tuesday January 03, 2023 @11:02AM (#34233142)
Psychiatry barely understands HOW exactly many prescription meds work so don't expect exact answer on how non-prescription substances work.

But if approached properly, single session with psychedelics may have beneficial effects of months or even years of psychotherapy. Week or two after such session you start noticing that some things simply stopped being problematic.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by briffle on Tuesday January 03, 2023 @12:01PM (#34234154)
nothing better than seeing expensive ad-buys for very expensive drugs, and they say "XXXXX is thought to work by".. you have spent millions on development, billions on marketing, and you think???
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by hericium on Tuesday January 03, 2023 @12:14PM (#34234335)
Substances are tested and when it is found that they have beneficial effects on certain conditions, outweighing negative side-effects in individuals with these conditions - they are accepted for use after clinical phases.

Would you rather have no meds for some conditions because we don't fully understand how existing ones work, or would you dissect living humans' brains for faster research?

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by bjt2n3904 on Tuesday January 03, 2023 @11:17AM (#34233390)
What you're witnessing is a radical restructuring of what is socially acceptable, or seen as good.

This statement about what is "good for society" can't be evaluated by statistics or metrics. It has to be believed, taken on faith.

Oh, they'll cite studies about miraculous results with overcoming addiction and depression. Pardon me for being skeptical about the massive amount of junk science that has over promised, under delivered, or been outright unrepeatable.

This is no different than the "AI" algorithms that are quickly making their way into decision making in society. It's a black box that worked great in the lab, so let's ship it to everyone. Surely it will be good for us!

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by throwaway4aday on Tuesday January 03, 2023 @11:30AM (#34233616)
> This statement about what is "good for society" can't be evaluated by statistics or metrics

I'd beg to differ. One can think up any number of metrics that would be inarguably good for society. Reduction in suicide would be a huge one. Reduced crime rate. Reduced addiction rate. Increase in lifespan. Increase in standard of living. Reduction of domestic violence. There are many more dimensions you could measure, establishing direct causation is the tricky part but it is certainly possible to establish if the state of society in general is improving.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by bjt2n3904 on Tuesday January 03, 2023 @12:23PM (#34234514)
No, you've missed my point completely. You are talking about the ends. I'm talking about the means.

Yes, a society with less suicide is a better thing. We can achieve that in many ways -- however, some ways come with significant or unpredictable side effects.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by lurquer on Tuesday January 03, 2023 @11:27AM (#34233558)
Don’t remove fences unless you are damn sure why they were put up in the first place.

The Gods of the Copybook Headings will return as they always do.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by Stupulous on Tuesday January 03, 2023 @11:45AM (#34233865)
It's not as though this is some thousand-year-old fence; psychadelics were illegalized under Nixon. If there was a reason other than 'they are drugs', it has not been made public, and all research at the time suggested that they should not have been illegalized. I'm open to being told I'm wrong, but 3 pages of google results did not push me in that direction.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by notch656c on Tuesday January 03, 2023 @12:07PM (#34234239)
These drugs have been illegal for a lifetime. It's hard to get people to accept even overwhelmingly beneficial technology into the main fold of society. I'm not optimistic anything beyond weed is gonna get legalized federally in our lifetime.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by OkayPhysicist on Tuesday January 03, 2023 @01:07PM (#34235220)
As cannabis (and now psilocybin) have demonstrated, we don't really need federal legalization to make significant strides at the state level. If anything, it's a positive pushback against nearly a century of dramatic overreach by a federal government granted far too much power. At some point, the federal government will have to face the awkward situation that 100% of the desirable to live in states are in open contempt to federal law, and they have to play catch-up.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by notch656c on Tuesday January 03, 2023 @01:26PM (#34235560)
Generically (not always true) red states have that for gun stuff (decriminalized unregistered / federally illegal NFA items) and blue states have that for pot and maybe even something else. It's hard for me to imagine the government will eventually catch up to freedom-leaning on either side, but I agree improvements at the state level is far better than nothing.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by jobs_throwaway on Tuesday January 03, 2023 @11:49AM (#34233938)
If you do the slightest bit of research into the criminalization of drugs in the US you will find that the people putting up those fences were laughably far from protectors of society. They were demonstrably more motivated by racism and classism than by a desire to safeguard social progress.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by notch656c on Tuesday January 03, 2023 @12:03PM (#34234185)
I think we're better off with a rich, mixed, and multicultural society but it may actually be true that a more homogenous society that tosses fringe races into the shredder or whatever is actually a safer place for the "right" people. Maybe they were protectors in their own racist way.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by lurquer on Tuesday January 03, 2023 @12:30PM (#34234635)
US laws are not the fence.

Well-functioning societies have steered clear of intoxication. A

A Clear-headed, rational, and objective view of reality is the goal.

There’s nothing new about messing with your perception of reality.

Wise men steer clear of it. Wise men counsel against intoxication of any kind. Fools don’t ask why.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by notch656c on Tuesday January 03, 2023 @12:39PM (#34234785)
Spending a tiny fraction of your life intoxicated allows you to make rational decisions despite occasional enjoying altered consciousness. There may be some level of brain damage but depending on the substance and how often it's used I question whether it's necessarily going to be the limiting factor in the aging body.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by andrew_ on Tuesday January 03, 2023 @12:52PM (#34234999)
There is much new speculation by historians and archeologists that psychedelics are widely responsible for giant leaps in civilization and "society." Your take is a puritanical, modern view without regard to history or nuance.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by jobs_throwaway on Tuesday January 03, 2023 @01:38PM (#34235798)
Can you give a few examples of such well-functioning societies?
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by mythrwy on Tuesday January 03, 2023 @04:04PM (#34238029)
I think maybe there is no "clear headed and rational view" of reality in truth.

There is only perspective, which somehow relates to a thing we like to call "reality" but the relationship is tenuous at best and doesn't always directly correspond.

Understanding the role of perspective I believe can be valuable. Sometimes maybe a shakeup helps to understand perspective is just that, or otherwise produce a different way of looking at things.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by kbelder on Wednesday January 04, 2023 @04:47PM (#34252286)
Your comment is sensible and, apparently, roundly rejected.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by jobs_throwaway on Tuesday January 03, 2023 @11:45AM (#34233877)
no one is going to force you to take psychedelics. I understand and support skepticism, but I have yet to hear a cogent argument backed by evidence for why these substances should be so harshly criminalize. The overwhelming consensus among experts is that these drugs are at the very least much safer than alcohol and many prescription drugs like adderall
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by spritefs on Tuesday January 03, 2023 @03:45PM (#34237755)
People don't make decisions in a vacuum. I'm personally less worried about myself and more about children who don't know any better and fall for all the reddit-tier bullshitting with respect to these substances
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by jobs_throwaway on Tuesday January 03, 2023 @04:06PM (#34238050)
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by burnished on Wednesday January 04, 2023 @06:29AM (#34244379)
I think you might be missing all the first hand experiences where it was a powerful good. Or maybe not, those have to be taken on faith after all.

Not that being skeptical about this is bad, frankly its good, but probably best when it is specific and focused into criticism.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by Stupulous on Tuesday January 03, 2023 @11:21AM (#34233472)
As a depression treatment, it far exceeds the state-of-the-art SSRIs, which perform only slightly better than placebo. It's cheaper, more effective, and lasts longer. ~10% of Americans suffer from depression, and more than a third of them don't respond to SSRIs at all. Dramatically reducing the suffering of 3% of the population at net-negative cost is a big deal.

For comparison to topics-de-jour, in the US 0.3% of the population will get an abortion in a given year, 3.5% are gay/bi, 0.3% are trans, <0.03% die from gun violence (and over half are suicides potentially reduced by this treatment) each year, and about 1/40th of them are killed by law enforcement. Improvements in these areas will have a smaller effect size (ie. protecting gay marriage will not improve the lives of gay people as much as curing someone's depression will, gun control will not end all gun violence).

Big caveat here is that this treatment is relatively new, and depression treatments tend to be promising initially with results that fade in the long term. Additionally, the legalization of that treatment does not mean everyone who needs it will get it. On the other hand, depression is only one of the many issues that can be treated with psychadelics. We'll have to wait and see

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by lostmsu on Tuesday January 03, 2023 @11:31AM (#34233631)
I am curious about side effects, especially long term IQ changes.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by Stupulous on Tuesday January 03, 2023 @11:51AM (#34233969)
Absolutely, I should have brought up risks as well. Triggering early schizophrenia is a big one, personality changes also seem like a significant concern. I'm not aware of any IQ changes- if you have a study, send it my way if you please. If you're just gesturing at the fact that long-term research is lacking, I'm very much in agreement.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by w1nst0nsm1th on Sunday January 08, 2023 @11:24AM (#34300396)
Hallucigenic drugs are probably not good for math performance.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by bradly on Tuesday January 03, 2023 @12:03PM (#34234175)
Fwiw at least in the US it not likely to be cheaper. Until covered by insurance, a professionally administered experience will most likely be be similar to a guided ketemine session which is currently around $450 a session when it costs penny to make.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by asdff on Tuesday January 03, 2023 @02:32PM (#34236742)
I get why some people would want or need a physician, but these drugs should be offered at cost in take home form too. We let people take opioids and amphetamines at home without supervision, and for most people that's fine.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by sowbug on Tuesday January 03, 2023 @02:44PM (#34236915)
I'm with you in spirit, but practically speaking it's an excellent idea to have a friend with experience to accompany you during your first session.

Even if your friend just sits there for four hours while reading a book, it's comforting to know that someone you trust is there to say "yes" when you start asking "is this really happening?" That can make the difference between a wonderful experience and an alarming one.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by bradly on Tuesday January 03, 2023 @04:22PM (#34238258)
They do. Sublingual ketemine is about $3 a dosage with a prescription, but it is usually only offered after a series of IV or IM treatments.
Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by StanislavPetrov on Tuesday January 03, 2023 @10:42PM (#34241745)
>Fwiw at least in the US it not likely to be cheaper.

It is much cheaper if you have cows nearby.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by more_corn on Thursday January 05, 2023 @05:46PM (#34268047)
Compare that to SSRIs that you have to take for 3 weeks before they either succeed or fail (and have unpleasant side effects). Also suicide while coming down off of SSRIs is unfortunately very common.

Contrast with: One session of psychedelic assisted therapy has been shown to offer months of relief from depression.

I’m not saying it’s a magic cure, just that we owe it to ourselves to continue to study psychedelic assisted therapy.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by throwaway4aday on Tuesday January 03, 2023 @11:25AM (#34233538)
I think it could still qualify if the only outcome is that it reduces the amount of resources and power given over to enforcement agencies in the drug war. However, we won't see positive outcomes unless that energy is redirected towards prosecuting actual crimes committed against people and property.

If psychological and medical research on psychoactive substances is successfully resumed I believe we will see helpful and possibly ground breaking applications of these drugs. They're indisputably powerful compounds, the question is simply whether those effects can be harnessed by medicine and therapy to provide long lasting interventions.

Re:Legal Use of Hallucinogenic Mushrooms Begins in Oregon by Loveaway on Tuesday January 03, 2023 @11:37AM (#34233731)
Humans are the most insane species on this planet. Most problems of society do not stem from a lack of resources, but from a severe cluelessness of our own nature. If you could ask any animal for advise on the human condition, I'd bet they'd be utterly baffled as to wtf we're doing or trying to do. Mushrooms give perspective. Among all the noise, they tend to reveal a more sane view of life and let people recognize what's truly important. I think if more people are open for trying it society will likely change for the better.