News for hackers. Stuff that matters.
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by JoeAltmaier on Friday April 08, 2022 @04:37PM (#30962223)
Must be lots of low-hanging fruit in biological treatments.

See, I went camping with the Scouts on Isle Royale, at the end of the week we were comparing mosquito bites, averaging about 100 per. Then a young man Luke said offhand "Mosquitoes don't bite me."

And sure enough, his skin was totally clear. I said "Luke, you bottle that, you're a millionaire."

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by ccleve on Friday April 08, 2022 @05:19PM (#30962631)
Related: https://www.caryinstitute.org/news-insights/media-coverage/h...

A man who studies ticks was bitten so many times that his body developed antibodies to tick saliva, which are now so powerful that they kill the ticks.

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by x1798DE on Friday April 08, 2022 @04:47PM (#30962325)
I used to get mosquito bites but I stopped getting them as an adult. I realized after a while that my skin stopped reacting to them even though the mosquitos were still biting me.

I recently managed to coax one into biting me to test my hypothesis. I felt it go into my skin and watched it suck for a bit, but it didn't get particularly engorged on it. No mark the next day. My son had a bitemark from a non-deliberate bite, though.

It seems to be a known phenomenon (though I have no idea why it happened to me): https://outdoors.stackexchange.com/questions/4310/is-it-poss...

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by emerged on Friday April 08, 2022 @05:15PM (#30962609)
I think for some of us they literally don’t even bite anymore. They certainly have preferences in blood type. I also have super visible veins as a relatively thin athletic person, yet they just seem to have no interest in what’s on the menu.

It’s quite a luxury as someone who spends lots of time on trails. But I also feel somehow offended. What’s so bad about MY blood?

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by vmception on Friday April 08, 2022 @06:07PM (#30963094)
I believe they all follow trails of your breath, which is why they can be reliably found above your bed when inside

So its likely about how that smells

Or other trails toward you, while they probably would enjoy your blood in actuality even if they think they’re detecting something related to how the meal would taste or its nutrition levels by proxy

Let me know what you all know!

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by ashtonkem on Saturday April 09, 2022 @12:17AM (#30965245)
> So its likely about how that smells

I thought the theory was that they follow the CO2 we exhale.

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by vmception on Saturday April 09, 2022 @12:50AM (#30965345)
Yes thats the one, what word would you like to use for that sensory molecule detection

There is still some difference in who they choose to follow or act upon so I’m grasping for where that difference is. Could be something alongside the CO2

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by ashtonkem on Saturday April 09, 2022 @01:23AM (#30965461)
Humans exhale all kinds of stuff aside from just CO2, including moisture and other metabolic byproducts depending on what you’re eating. Probably some bacterial metabolic products from our mouths too.

I guess I’m less into the semantic difference between “smell” and “detect” and more whether it’s the CO2 they’re following or something else we exhale regularly.

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by vmception on Saturday April 09, 2022 @01:26AM (#30965472)
Yeah I’m curious too, I think thats the right direction to research
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by ashtonkem on Saturday April 09, 2022 @12:16AM (#30965244)
Oh, that’s an interesting observation I’ve never realized until you pointed it out. I’ve always been the target of mosquitos more than anyone else I know, but it seems to get worse the fitter I am. Now that I’m a bit pudgy and out of shape, I haven’t had anywhere near as many bites.

But, to be fair for me being fit and being in the regions where mosquitos exist en masse is a related phenomenon. Out of shape me spends less time on trails than fit me.

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by refurb on Saturday April 09, 2022 @04:21AM (#30966178)
They certainly have preferences in blood type.

How would they know your blood type before biting you?

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by samizdat311 on Saturday April 09, 2022 @10:46AM (#30968472)
The idea one of the preceding comments seemed to imply was that they sample a bit first.

> I felt it go into my skin and watched it suck for a bit, but it didn't get particularly engorged on it. No mark the next day.

So it might follow that with one resistant (R) and one non-resistant person (NR) exposed to a few dozen mosquitoes, NR will end up with lots of visible bites while R will be relatively unscathed - even though the mosquitoes might have sampled them each equally.

I know too that some mammals (e.g. mice) will sample a small amount of food (e.g. rodent poison), and then return later to try more if the food hasn't had ill effects.

I'm not sure that mosquitoes have anything like a memory capacity for this, but maybe something similar mediated via pheromones could be happening. (And something like pheromones could also signal to other mosquitoes that there's good eatin' to be had).

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by hackernewds on Saturday April 09, 2022 @12:34AM (#30965293)
It's possible you're getting bit but not seeing the symptoms afterwards
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by knodi123 on Friday April 08, 2022 @04:54PM (#30962384)
> "Luke, you bottle that, you're a millionaire."

Or you get assassinated by Big Mosquito Repellent. I wouldn't mess with those people. Stick to inventing a cheap carbon-negative replacement for gasoline. Far fewer people angry at you upsetting the apple cart.

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by MisterBastahrd on Friday April 08, 2022 @06:24PM (#30963254)
The little permetherin pads that OFF sells are the best things anywhere. I used to live in a suburb of New Orleans surrounded by swamps, and those things drive mosquitos away. Vastly better than mosquito coils and reusable... just dip them in more permetherin solution and they'll last for another 4 hours. Someone needs to come up with a system that involves a rechargable battery pack and a tiny heating element along with a little kit for redipping and storage. Sportsmen everywhere would love that product.
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by chiefalchemist on Friday April 08, 2022 @05:07PM (#30962529)
Fewer? Perhaps. But the depth of those pockets are 100× Big Mosquito Repellent.

Put another way, we've been going to war over oil for years. One more body on that pile isn't difficult to imagine.

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by Nition on Friday April 08, 2022 @05:23PM (#30962665)
I think the previous comment was being sarcastic. And sort of making a joke that whatever you go after, you're going to upset some big corp somewhere.
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by cellis on Friday April 08, 2022 @06:59PM (#30963516)
> 100x Big Mosquito […]

off by about 3 or 4 orders of magnitude unfortunately

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by rootusrootus on Friday April 08, 2022 @05:32PM (#30962762)
> "Mosquitoes don't bite me."

That seems less likely than "My body doesn't generate a histamine response which results in a raised bump at the bite location."

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by newman8r on Friday April 08, 2022 @07:15PM (#30963641)
I'm one of those people who's rarely affected by mosquitoes - but I'll still get bit. I'd estimate I get 1 bite for every 5 that anyone else I'm hiking with does. People will be complaining about how bad the mosquitoes are and I'll have ~0-2 bites.

So in my case, I do have a response to at least some bites, but consistently fewer than anyone else I'm with.

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by hombre_fatal on Saturday April 09, 2022 @11:33AM (#30968916)
Mosquitoes rarely bite me unless I'm their only option. They won't bite me at all if someone else is in the vicinity (so, my poor girlfriend).

You can quickly confirm whether it's no biting vs no reaction by the fact that you can see them flying around and landing on you. Or rather, around everyone else except you. They aren't invisible. Here in the tropics, other people will be covered in them.

Re:Turning back the clock: Human skin cells de-aged by 30 ye... by smileysteve on Friday April 08, 2022 @05:44PM (#30962875)
The secret we had in scouts was to take garlic supplements starting a week before. Did great at preventing all sorts of bites.
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by jelliclesfarm on Saturday April 09, 2022 @01:02AM (#30965382)
Neem oil here. It doesn’t kill insects..repels them and renders them sterile.
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by elorant on Friday April 08, 2022 @05:21PM (#30962649)
My dad is like that. I'll stay on a veranda for five minutes wearing short pants, I'll easily get two or three bites. He stays for half an hour, he's invisible.
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by Bellamy on Friday April 08, 2022 @04:44PM (#30962289)
You gotta explain this to me. I have no idea what this is about but made me laugh.
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by JoeAltmaier on Friday April 08, 2022 @04:52PM (#30962370)
Whatever gene or skin oil or whatever, Luke has it. I wish I could do that. I'd pay cash.
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by mrleinad on Saturday April 09, 2022 @07:47AM (#30967191)
Just a small pet peeve of mine: do mosquitoes bite or sting?
Re:Turning back the clock: Human skin cells de-aged by 30 ye... by InCityDreams on Saturday April 09, 2022 @10:00AM (#30968140)
Stab/ Puncture?