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Re:BioNTech alone could lift German economy by 0.5% this year by lm28469 on Tuesday August 10, 2021 @11:14AM (#28129841)
When people ask for the difference between US and EU business thinking I'll send them that comment.

This shit simply doesn't fly in Germany, it's so insane that no one would ever think about pricing life saving drugs that high

Re:BioNTech alone could lift German economy by 0.5% this year by dang on Thursday August 12, 2021 @12:51AM (#28152089)
Please don't take HN threads into nationalistic flamewar. It's tedious, poisonous, and off topic. Moreover, you don't know anything about where the other user was posting from.

https://news.ycombinator.com/newsguidelines.html

Re:BioNTech alone could lift German economy by 0.5% this year by wil421 on Tuesday August 10, 2021 @11:44AM (#28130244)
It costs the same in the US and Germany, $19.50. There will always be a scummy Martin Shkreli[1] type and Germany is not immune to this. See VW and Wireguard. BaFin seemed to ignore red flags presumably because it was another darling of the German economy similar to VW.

The US also moves very slow legally but the reckoning is coming for Pharmaceutical price gouging. Lots and lots of hype in the past few years about it.

[1] https://www.usatoday.com/story/money/2018/03/09/martin-shkre...

Re:BioNTech alone could lift German economy by 0.5% this year by OJFord on Tuesday August 10, 2021 @12:19PM (#28130713)
> There will always be a scummy Martin Shkreli[1] type and Germany is not immune to this. See VW and Wireguard.

I assume you are referring to Wirecard [0] and not privy to information which I am not about the stellar Wireguard [1]? :)

[0] - https://en.wikipedia.org/wiki/Wirecard_scandal

[1] - https://www.wireguard.com/

Re:BioNTech alone could lift German economy by 0.5% this year by wil421 on Tuesday August 10, 2021 @10:07PM (#28137114)
Yes autocorrect on my phone.
Re:BioNTech alone could lift German economy by 0.5% this year by albatross13 on Tuesday August 10, 2021 @11:56AM (#28130423)
How did you figure out it was 19.50 a dose in the US? As far as I've seen, Pfizer has all but ensured their contracts with various governments are not publicly available.
Re:BioNTech alone could lift German economy by 0.5% this year by wil421 on Tuesday August 10, 2021 @12:05PM (#28130534)
It’s mentioned in this article[1] but they won’t tell you the specific contract. I assumed it was universal but I guess Federal and State agencies negotiate their own contracts.

My state will pay for it wether or not you have insurance.

> Pfizer's agreement with the federal government is the most lucrative to date. The government agreed to buy 100 million doses of the Pfizer coronavirus vaccine, being developed with German biotech firm BioNTech, for $1.95 billion. That works out to about $20 per dose.[2]

[1]https://www.fiercepharma.com/pharma/pfizer-eyes-higher-covid...

[2] https://www.gpb.org/news/shots-health-news/2020/08/08/prices...

Re:BioNTech alone could lift German economy by 0.5% this year by odiroot on Tuesday August 10, 2021 @12:33PM (#28130898)
> See VW and Wireguard

You probably meant Wirecard.

Re:BioNTech alone could lift German economy by 0.5% this year by suction on Tuesday August 10, 2021 @12:09PM (#28130589)
What VW did was dirty, but didn't really include a component of price gouging. Wiregard was straight-up fraud, by an agent working for Russia and greediness paired with stupidity on part of the CEO etc.

Not to diminish the negative effects for the reputation of Germany of these two cases, but they both aren't an expression of libertarianism like the idea that a company has no moral obligations to offer an important drug for an affordable price, but should make as much money as possible from it, which wouldn't fly in Germany.

Re:BioNTech alone could lift German economy by 0.5% this year by manuel_w on Tuesday August 10, 2021 @12:42PM (#28131018)
> by an agent working for Russia

You're talking about Jan Marsalek, right? That he worked for Russia is new to me.

According to [1], he did business in Russia, but that doesn't make him work for Russia. If you have more information in that, I'd be interested to hear.

[1] https://thebell.io/en/what-links-russia-to-germany-s-wirecar...

Re:BioNTech alone could lift German economy by 0.5% this year by suction on Wednesday August 11, 2021 @02:21AM (#28138689)
Hard to find an English speaking source for it (we know how friendly the UK and Russian governments are lately), but for example, here https://www.nzz.ch/wirtschaft/wirecard-jan-marsaleks-spuren-... are claims that Marsalek himself admitted relations with the FSB.
Re:BioNTech alone could lift German economy by 0.5% this year by lostlogin on Tuesday August 10, 2021 @11:45AM (#28130253)
> When people ask for the difference between US and EU business thinking I'll send them that comment.

The comment you refer to is also a good summary of US healthcare practices and billing.

Re:BioNTech alone could lift German economy by 0.5% this year by oaiey on Tuesday August 10, 2021 @11:24AM (#28129949)
It does not work because of our insurance system. In all other businesses it would work.

Ask yourself what a security package in any German car brand costs extra. Camera in the rear, extra airbags, lidar/ai, speed sign scanning,.. that is not default but a very expensive extra.

Re:BioNTech alone could lift German economy by 0.5% this year by mathverse on Tuesday August 10, 2021 @12:10PM (#28130600)
I think countries would simply threaten with nationalizing the company if the company tried something ridiculous during a global pandemic.
Re:BioNTech alone could lift German economy by 0.5% this year by skybrian on Tuesday August 10, 2021 @11:23AM (#28129939)
I agree that they shouldn’t charge that much, but it’s definitely worth that much, and probably a lot more.

Maybe they should have done a charity auction of a few doses at the beginning to billionaires to show what it’s really worth, for the marketing value of “you’re getting a medicine worth hundreds of thousands of dollars for free.” Maybe that would convince the anti-vaxers?

Re:BioNTech alone could lift German economy by 0.5% this year by input_sh on Tuesday August 10, 2021 @12:02PM (#28130498)
I agree on the worth part. I could afford to spend hundreds of euros to go to a nearby country and get an EU-approved vaccine months ago. Overall I estimate those hundreds of euros got me vaccinated about six months earlier than I would be in my own country.

During that time months ago one of our politicians came out and said that thousands of my fellow citizens that did the same were "wasting money on something that only costs €10", but that means nothing when you can't get to that something that only costs €10.

Re:BioNTech alone could lift German economy by 0.5% this year by trynumber9 on Tuesday August 10, 2021 @02:52PM (#28132685)
Why the US? The poster you reply to is from London. It's even in his user name. Did any US companies price their vaccines high either?
Re:BioNTech alone could lift German economy by 0.5% this year by usrusr on Tuesday August 10, 2021 @11:26AM (#28129990)
Even Germany bought from Pfizer, not from Biontech, which indicates that the differences can't be as wide as you suggest (or as gp suggests)
Re:BioNTech alone could lift German economy by 0.5% this year by danck on Tuesday August 10, 2021 @11:35AM (#28130112)
It may help to know that BioNTech were in fact the developers of the Pfizer vaccine:

https://en.wikipedia.org/wiki/Pfizer%E2%80%93BioNTech_COVID-...

Re:BioNTech alone could lift German economy by 0.5% this year by adventured on Tuesday August 10, 2021 @11:53AM (#28130376)
> It may help to know that BioNTech were in fact the developers of the Pfizer vaccine

It may help to know that Pfizer directly helped with the development - not just the manufacturing & distribution - and deserves some credit as well (even if not as much as BioNTech).

From their March 27, 2020 co-development press release:

"Pfizer and BioNTech to Co-develop Potential COVID-19 Vaccine"

"Builds on 2018 agreement to jointly develop an mRNA-based influenza vaccine"

"The collaboration aims to accelerate development of BioNTech’s potential first-in-class COVID-19 mRNA vaccine program, BNT162, which is expected to enter clinical testing by the end of April 2020. The rapid advancement of this collaboration builds on the research and development collaboration into which Pfizer and BioNTech entered in 2018 to develop mRNA-based vaccines for prevention of influenza."

Re:BioNTech alone could lift German economy by 0.5% this year by suction on Tuesday August 10, 2021 @12:11PM (#28130613)
Pfizer surely did help monetarily (investments) and offers global distribution, but that doesn't mean they had any hand in developing the science and the product. Any big pharmaceutical company, like Bayer, could have done the same, but randomly Pfizer got lucky this time.
Re:BioNTech alone could lift German economy by 0.5% this year by spywaregorilla on Tuesday August 10, 2021 @01:01PM (#28131268)
Pfizer played a major role in the trials, which is an enormous part of the process.
Re:BioNTech alone could lift German economy by 0.5% this year by suction on Wednesday August 11, 2021 @02:17AM (#28138665)
Which, again, any big pharmaceutical company would have offered to a drug developer, and was in no way a special attribute of Pfizer.
Re:BioNTech alone could lift German economy by 0.5% this year by spywaregorilla on Wednesday August 11, 2021 @11:21AM (#28143068)
I mean yeah, but it's still a large complicated task. I don't think executing major projects like this should be handwaved because there's alternative options.

This is equivalent to saying there's nothing special about biontech as any specialist in novel MRNA vaccines could have developed these. Which did happen, at moderna.

Re:BioNTech alone could lift German economy by 0.5% this year by kken on Tuesday August 10, 2021 @12:37PM (#28130954)
They started working together even before Covid.

https://biontech.de/sites/default/files/2019-08/20180816_Bio...

The Pfizer head of vaccine research seems to be from Germany as well.

Re:BioNTech alone could lift German economy by 0.5% this year by skybrian on Tuesday August 10, 2021 @12:31PM (#28130883)
That’s discounting the difficulty of manufacturing these new vaccines, which only a few companies know how to do, and also required many subcontractors.

If it were easy, it wouldn’t have taken so long to scale up manufacturing, even by the largest pharmaceutical companies.

Re:BioNTech alone could lift German economy by 0.5% this year by suction on Wednesday August 11, 2021 @02:17AM (#28138668)
What's the endgame here - to point out "Pfizer is awesome!!"? Seems a little strange.
Re:BioNTech alone could lift German economy by 0.5% this year by usrusr on Tuesday August 10, 2021 @11:49AM (#28130308)
Sure, and they can be proud of it and make all that money, but if you are in the market to ramp up a vaccination programme, you talk to Pfizer and not to Biontech. Almost like you'd go to Apple and not to FHG IIS for buying an iPod.

(I'm pretty sure that this comparison is a wild exaggeration of what actually happened and that Biontech representatives were very much involved in all the talks, but I assume more in an expert advisor role than as someone with actual influence on the outcome)

Re:BioNTech alone could lift German economy by 0.5% this year by kansface on Tuesday August 10, 2021 @01:10PM (#28131420)
> This shit simply doesn't fly in Germany, it's so insane that no one would ever think about pricing life saving drugs that high

A sizeable portion of my friends and coworkers managed to work the system to gain access to vaccines well before they otherwise would have. I'd strongly prefer the honest version of that system, wherein we wouldn't pretend that elites wouldn't cut the queue to finagle vaccines for themselves and their families. One option would have been setting aside ~5% of the total supply and putting it on the open market. I'd guess early doses would have gone for a few thousand dollars and we could have used the money to support vaccinations elsewhere.

Re:BioNTech alone could lift German economy by 0.5% this year by jopsen on Tuesday August 10, 2021 @11:25AM (#28129971)
Just a reminder it was the US that blocked vaccine exports.

While we in the EU let the free market handle things.

Of course, EU countries were smart enough to buy vaccines collectively :)

Re:BioNTech alone could lift German economy by 0.5% this year by TMWNN on Tuesday August 10, 2021 @04:04PM (#28133604)
>Just a reminder it was the US that blocked vaccine exports.

There is and has never been a US vaccine export ban, and the US has not seized vaccines meant for other countries.

The Trump administration last year signed gigantic contracts for every planned vaccine, because no one knew which ones would work. Like, enough for every American from one manufacturer, let alone the current four major available ones. More importantly, the contracts guaranteed the US the earliest deliveries.

By early June 2020 (<https://web.archive.org/web/20200603171013/https://www.nytim...>) the Trump administration had already identified and was planning to sign the aforementioned huge contracts with Moderna, AstraZeneca, J&J, Merck, and Pfizer. (An 80% success rate is fantastic in drug discovery.) By that time the US had already paid $2.2 billion to three of the companies. (Also note the skepticism throughout that any vaccines could be delivered anywhere within the timeframe the administration was promising.)

The UK signed a similar contract for the AstraZeneca vaccine. The EU and Canada did not assure themselves of such quantities. Canada also bet on CanSino because it was afraid that the US would ban vaccine exports (which, again, never happened). Of course, the Chinese did not live up to the contract.

Before you say "But what about—", the Trump executive order from December 2020 merely sets up the legal framework to prohibit exports if desired. But that does not mean that the framework is invoked. Let me repeat: The US signed contracts that were a) huge in size/scope and b) from every pharmaceutical company working on a vaccine, which c) got the country the largest and among the first deliveries. The UK did the same thing with the AstraZeneca vaccine, and spent a lot of money to retool domestic plants to produce it in addition to the non-UK doses it bought.

(I don't disagree that to country B waiting on doses, the outcome is the same whether or not the cause is country A implementing an export ban or country A having bought up all the doses by having signed the contract first. But there is a difference.)

If the situation were different, might the US have implemented a ban on exports, similar to what the EU did implement toward Australia? Perhaps. But, fortunately, the US never faced this issue, because of the huge amounts of money it invested a year ago and the contracts it signed with said money.

>While we in the EU let the free market handle things.

Except Italy as I mentioned, blocking export of vaccine to Australia that the latter had paid for. More to the point, the EU did not ban vaccine exports more widely because it was afraid that the US would cut off component supply chains.

>Of course, EU countries were smart enough to buy vaccines collectively :)

... and because the aforementioned collective effort was delayed relative to the US and UK, the EU saw significant vaccine shortages earlier this year.

Re:BioNTech alone could lift German economy by 0.5% this year by jopsen on Friday August 13, 2021 @02:56AM (#28166233)
> the Trump executive order from December 2020 merely sets up the legal framework to prohibit exports if desired.

Not how I understood it. But it seems you're right, the US only used war time powers to force companies to fill their orders first. The effect is quiet similar, the EU (not even UK) employed such powers.

In either case, it was argued that this made negotiations easier for US.

And yes, it's a fair point that it didn't matter, because the US would have bought the vaccines at whatever price point :)

> Except Italy as I mentioned, blocking export of vaccine to Australia that the latter had paid for.

Fair point :)

> ... and because the aforementioned collective effort was delayed relative to the US and UK

The UK (and probably the US) invested in supporting research, but EU closed contracts for vaccine purchases sooner. (I suspect the EU also sponsored research, but didn't attach strings the same way the UK did)

-----

To be clear, I don't think I would argue that the EU did fantastically well here. Nor that it couldn't have done much better. Namely because it doesn't have a powerful administration, like the US does. (I'm not arguing that it should have one)

Whether or not all this was unfair is hard to tell. Lots of countries poured money into R&D. (Also not sure how relevant it is).

But it is a bit funny that the EU largely let the free market forces play out, while the US didn't.

Re:BioNTech alone could lift German economy by 0.5% this year by TMWNN on Friday August 13, 2021 @04:20AM (#28166693)
>Not how I understood it. But it seems you're right, the US only used war time powers to force companies to fill their orders first.

No. The US did invoke the Defense Production Act for certain medical equipment, to further ensure that its vaccine contracts are fulfilled first (<https://www.bloomberg.com/news/articles/2021-03-24/biden-use...>). (But, let me quote for others' benefit (<https://www.ft.com/content/82fa8fb4-a867-4005-b6c2-a79969139...>): "The DPA does not allow the administration to block exports overseas".)

The US's contracts would have been fulfilled first regardless (albeit more slowly) without the DPA, because (as I said) the US was the first and paid the most. We know this because the US's Pfizer contract explicitly prohibited the company from exporting US-produced vaccine doses until March 31, but the company only began to export US-produced doses at the end of April because it still had to fulfill said US contract first (<https://www.barrons.com/articles/pfizer-to-export-u-s-made-v...>).

Re:BioNTech alone could lift German economy by 0.5% this year by systemvoltage on Tuesday August 10, 2021 @11:29AM (#28130031)
Re:BioNTech alone could lift German economy by 0.5% this year by cmrdporcupine on Tuesday August 10, 2021 @11:58AM (#28130440)
The EU did the right thing ethically and let vaccines be exported to their allies. In the long run they caught up though.

Amazing that Canada was forced to import from the EU because we were prevented from importing from our nearest neighbour and "closest ally" and so were set back by two months on vaccinations.

Re:BioNTech alone could lift German economy by 0.5% this year by TMWNN on Tuesday August 10, 2021 @04:07PM (#28133647)
>Amazing that Canada was forced to import from the EU because we were prevented from importing from our nearest neighbour and "closest ally" and so were set back by two months on vaccinations.

There was never a vaccine export ban by the US (see my other comment for more on this). If I purchase an item before others, purchase by far the most quantities of that item, pay by far the most overall, and pay a considerable amount of money toward funding its development, I should expect that item before others. Any Kickstarter backer knows this; it's what the US and UK did, and what Canada and the EU did not.

By early June 2020 (<https://web.archive.org/web/20200603171013/https://www.nytim...>) the Trump administration had already identified and was planning to sign the aforementioned huge contracts with Moderna, AstraZeneca, J&J, Merck, and Pfizer. (An 80% success rate is fantastic in drug discovery.) By that time the US had already paid $2.2 billion to three of the companies. (Also note the skepticism throughout that any vaccines could be delivered anywhere within the timeframe the administration was promising.)

By contrast, look at Canada as counterexample. Consider Maclean's desperate attempt to spin its procurement difficulties (<https://www.macleans.ca/news/canada/where-did-canadas-vaccin...>). If you look past the predictable false eliding of the US's firstest-with-the-mostest contracts as an "export ban", the best the magazine can do is admit that

* all Canadian contracts with vaccine providers that actually delivered were signed between late July and late September

* all contracts were signed after the collapse of the CanSino deal, which Canada had loudly bragged about as proof of its savviness at obtaining vaccines ASAP and circumvent any perfidious US vaccine export ban (which, again, never happened), and which it has done its best since the collapse to pretend that said contract never existed

* the other contracts that the magazine cites as proof that CanSino wasn't the only basket Ottawa was putting all its eggs in are with VBI (Who?) and USask. They may or may not yet deliver effective vaccines, but it's all now a bit beside the point, eh?

Re:BioNTech alone could lift German economy by 0.5% this year by blibble on Tuesday August 10, 2021 @01:45PM (#28131877)
> The EU did the right thing ethically and let vaccines be exported to their allies.

no, it thought it had control over the situation and started virtue signalling that it was being ethical and that vaccine nationalism was only the sort of thing the Trump administration would do

and at the point it became apparent that it had lost control: the nationalistic flailing began

Re:BioNTech alone could lift German economy by 0.5% this year by jopsen on Tuesday August 10, 2021 @02:16PM (#28132271)
> no, it thought it had control over the situation and started virtue signalling...

As I understood it, the US had laws necessary to administratively enact export restrictions during emergencies.

I suspect the EU didn't have the same leaver it could just magically pull. Some individual countries might, but that's no use when production is distributed across the EU.

Unlike the US the EU doesn't have disasters management agencies, many things are left for individual countries.

Generally, there is no administrative authority in the EU that can really do much -- where as the US president can take a lot of actions. The EU would like have had to draft laws stopping exports, and those could be challenged in courts, etc.

More likely, the EU just didn't have an easy button to push, and nobody has agreed upfront on which cases such button should be used.

Re:BioNTech alone could lift German economy by 0.5% this year by blibble on Tuesday August 10, 2021 @04:59PM (#28134432)
> As I understood it, the US had laws necessary to administratively enact export restrictions during emergencies.

> I suspect the EU didn't have the same leaver it could just magically pull.

it was given these powers after it was obvious it had lost control of the situation:

https://www.independent.ie/business/brexit/eu-gets-new-power...

then it attempted to use the new powers against the UK

this backfired badly: if it had been enacted it would have created a border across Ireland, when the EU had spent the previous 5 years arguing that a border of exactly this type could never be created any circumstances

at which point it was forced politically to withdraw the measures

Re:BioNTech alone could lift German economy by 0.5% this year by jopsen on Friday August 13, 2021 @03:02AM (#28166276)
> it was given these powers after it was obvious it had lost control of the situation...

> this backfired badly: if it had been enacted it would have created a border across Ireland...

Yeah, creating such measures overnight probably wouldn't workout well.

Had consistent and thought-out policy existed upfront maybe it would have been a different story.

Of course Brexit probably would have ruined many such plans with factories distributed throughout EU and UK.

Re:BioNTech alone could lift German economy by 0.5% this year by jopsen on Tuesday August 10, 2021 @12:04PM (#28130521)
Really? We got the most vulnerable population vaccinated pretty quickly.

And today we have plenty of vaccines. Is it really a catastrophe that it took 2 months longer?

(Two summer months with weather slightly less conductive to virus transmission)

Re:BioNTech alone could lift German economy by 0.5% this year by cmrdporcupine on Tuesday August 10, 2021 @04:58PM (#28134422)
Nothing like people throwing rocks from the US where they had lots of vaccine supply but also an obscene supply of people who refuse to get it. Having advance supply has hardly done them any good, judging from this week's new case and hospitalization rates.
Re:BioNTech alone could lift German economy by 0.5% this year by thepasswordis on Tuesday August 10, 2021 @12:34PM (#28130915)
For much of the world there is no difference between $20, $1000, and $100,000.

This vaccine should be free. Covid is the biggest threat to the future of humanity that has existed since the development of nuclear weapons and we're holding back the solution over $20.

It's pathetic.

Re:BioNTech alone could lift German economy by 0.5% this year by refurb on Tuesday August 10, 2021 @11:22AM (#28129922)
Oh really? The first million dollar drug came out of Europe.

https://bioengineeringcommunity.nature.com/posts/45406-1-mil...

“The first gene therapy approved in the Western world is set to go on sale in Germany at a cost close to $1 million per treatment. The record-breaking price tag came to light in November 2014, when Amsterdam-based Uniqure and its marketing partner Chiesi, of Parma, Italy, filed a pricing dossier with German authorities to launch Glybera.”

Re:BioNTech alone could lift German economy by 0.5% this year by oaiey on Tuesday August 10, 2021 @11:25AM (#28129968)
The key difference: the insurences in Germany would never pay that.
[dead]
Re:BioNTech alone could lift German economy by 0.5% this year by systemvoltage on Tuesday August 10, 2021 @11:31AM (#28130053)
Your comment is just fanning the flames with no interesting discussion for the audience. When a counter point is presented, you're moving goal posts.

Moderna is selling vaccines for $20/pop. That's a US company.

Vaccines are also purchased by the Governments usually to be distributed for free. In US, you can get a COVID-vaccine shot for free anywhere in any state.