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Re:Suppressing a gene by using its antibody can lead to toot... by dannyw on Tuesday March 30, 2021 @10:46PM (#26642987)
It's so sad that most dentists optimise for billable revenue, even at the detriment of long term patient health.

Fillings for example always degrade and need repairs after X years. Drilling and filling even the smallest cavity puts that teeth on a lifetime progression to bigger and bigger fillings, eventually a root canal, eventually an implant.

Cavities, on the other hand can be arrested (stopped), and if small can even be remineralised. Yes, most dentists don't tell you that!

Careful monitoring and patient education on the other hand can lead to permanently keeping that natural teeth, as our teeth are living and can heal.

My personal lived experience: a dentist told me I must fill 2 cavities six years ago. I got a second opinion. That dentist told me I should wait, focus on oral care, chew xylitol gum, and use a toothpaste with novamin.

Both cavities have "arrested" and need no restorative work.

Disclaimer: Not a dentist. Listen to your dentist you trust, and get second opinions if you have doubt.

Re:Suppressing a gene by using its antibody can lead to toot... by donatj on Tuesday March 30, 2021 @11:13PM (#26643124)
Novamin toothpaste has been life changing for me. Cannot recommend highly enough. A tooth that was deteriorating and the dentist wanted to cap is now fine enough for them to simply keep an eye on.
Re:Suppressing a gene by using its antibody can lead to toot... by Benjamin_Dobell on Wednesday March 31, 2021 @03:45AM (#26644501)
I just started using toothpaste with nano-Hydroxypatite after a recommendation from a friend. Obviously I can't say much about its effectiveness long-term. But it feels amazing. Feels like there's a protective layer over the enamel - hopefully there actually is!

Apparently, nano-Hydroxypatite is even more effective than Novamin (which is still good): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121804/

If you're in Australia and struggling to find toothpaste with Hydroxypatite, Chemist Warehouse stock "Healthy Care Sensitive Propolis Toothpaste". So far, highly recommended.

Re:Suppressing a gene by using its antibody can lead to toot... by kristofferR on Friday April 02, 2021 @03:45AM (#26669712)
Another interesting teeth restoring substance I just discovered:

Oligopeptide P11-4 [1]

[1]https://en.wikipedia.org/wiki/Oligopeptide_P11-4

Re:Suppressing a gene by using its antibody can lead to toot... by social_quotient on Wednesday March 31, 2021 @03:51AM (#26644540)
Totally agree! The brands I use are - Apagard - Boka - CTx4
Re:Suppressing a gene by using its antibody can lead to toot... by social_quotient on Wednesday March 31, 2021 @03:49AM (#26644531)
I’ve had similar success with toothpastes containing “nano-hydroxyapatite” Amazon has several good ones.

I also have 2 kids, the youngest (4 yr old) had cavity issues which required intervention and then we started using the hydroxyapatite toothpaste and had no issues since.

I also headed down this path via looking for Novamin. I wish there was a reliable way to get it without the “is it fake” on Amazon. I’d gladly accept any reliable sources.

Re:Suppressing a gene by using its antibody can lead to toot... by Black101 on Wednesday March 31, 2021 @06:24AM (#26645507)
I ordered some from Canada, made in Canada, using Ebay (about as reliable as Amazon but it doesn't come from India and it is cheaper).
Re:Suppressing a gene by using its antibody can lead to toot... by nickspacek on Wednesday March 31, 2021 @10:16AM (#26647605)
I went looking on Ebay but couldn't find anything in Canada, do you mind sharing the brand or keyword?
Re:Suppressing a gene by using its antibody can lead to toot... by Black101 on Wednesday March 31, 2021 @02:21PM (#26650974)
Sorry I was talking about the Novamin one... I think the nano-hydroxyapatite one is available in the US.
Re:Suppressing a gene by using its antibody can lead to toot... by dharma1 on Wednesday March 31, 2021 @05:04AM (#26645003)
Have you checked out Biomin? It’s meant to be an improved version of Novamin.
Re:Suppressing a gene by using its antibody can lead to toot... by blackrock on Wednesday March 31, 2021 @12:39AM (#26643581)
I have never heard of this Novamin toothpaste before. Nor has any of my dentists ever recommended it.

It looks like the popular brand is Sensodyne.

Re:Suppressing a gene by using its antibody can lead to toot... by elsonrodriguez on Wednesday March 31, 2021 @01:22AM (#26643800)
Sensodyne does not have Novamin in the USA(insert conspiracy theory here). You'd either have to import it from a reputable supplier, or try an alternative like Apagard or Biomin F(both of those have to be imported too, but are more readily available).
Re:Suppressing a gene by using its antibody can lead to toot... by spyder on Wednesday March 31, 2021 @03:23AM (#26644392)
Article from 2018 about that:

"As of the time of this update, Sensodyne toothpaste with NovaMin is now available on Amazon to buyers in the USA, directly from Sensodyne/GSK."

https://medium.com/@ravenstine/the-curious-history-of-novami...

https://www.amazon.com/Sensodyne-Protect-Whitening-Toothpast...

Re:Suppressing a gene by using its antibody can lead to toot... by throw1234651234 on Wednesday March 31, 2021 @02:19PM (#26650948)
That article really helped me understand what this is all about, ty!
Re:Suppressing a gene by using its antibody can lead to toot... by bemmu on Wednesday March 31, 2021 @01:30AM (#26643834)
Quick googling found a funny metastudy: "The articles from the database obtained for further review was N = 1. According to the study..."
Re:Suppressing a gene by using its antibody can lead to toot... by boruto on Wednesday March 31, 2021 @03:31AM (#26644444)
Haha, I read the same after googling.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068624/

Re:Suppressing a gene by using its antibody can lead to toot... by ClumsyPilot on Wednesday March 31, 2021 @05:39AM (#26645219)
I never heard of Novamin, but I used Sensodyne for years becase it tastes better.
Re:Suppressing a gene by using its antibody can lead to toot... by blackrock on Wednesday March 31, 2021 @02:37PM (#26651188)
Has it helped with maintaining the health of your teeth?
Re:Suppressing a gene by using its antibody can lead to toot... by logicchains on Tuesday March 30, 2021 @11:17PM (#26643154)
>Cavities, on the other hand can be arrested (stopped), and if small can even be remineralised. Yes, most dentists don't tell you that!

>Careful monitoring and patient education on the other hand can lead to permanently keeping that natural teeth, as our teeth are living and can heal.

Do you have any sources for this? I'm not disagreeing; I hope it's true.

Re:Suppressing a gene by using its antibody can lead to toot... by tablespoon on Tuesday March 30, 2021 @11:29PM (#26643207)
> Do you have any sources for this? I'm not disagreeing; I hope it's true.

My dentist prescribed/sold me this for some decay: http://www.mi-paste.com/whyMIP.php

She said it works sometimes. I definitely like this conservative approach better than my last dentist's, who filled 4 teeth unnecessarily because his DIAGNOdent beeped once.

Re:Suppressing a gene by using its antibody can lead to toot... by drawfloat on Wednesday March 31, 2021 @12:44AM (#26643606)
I'd be suspicious of those claims – anecdotal but, unless US doctors differ greatly, neither of those are secrets that have been withheld from me by dentists in 3 European countries.

In fact the second statement is surely the basis for most modern dentistry...?

(I said US there because it's an assumption that the US approach to dentistry may be different to rest of the world. From afar, seems more cosmetic focused with a lot more emphasis put on whitening/straightening/veneer/fixing procedures than over here)

Re:Suppressing a gene by using its antibody can lead to toot... by blamestross on Wednesday March 31, 2021 @08:31AM (#26646366)
Well it isn't like dentists in the US are real doctors like in other countries
Re:Suppressing a gene by using its antibody can lead to toot... by tmamic on Wednesday March 31, 2021 @04:00AM (#26644602)
https://youtu.be/3zL4Hou1P-c?t=187

Mineralisation of tooth is a constant process with a tug-of-war between pathogenic and protective factors [3:09].

If it's in the balance, of the remineralisation factors prevail, you can stop the progress of the cavity. But deeper the cavity, this is harder to achieve.

Arrested dental caries is an official diagnosis recognized by ADA: https://www.icd10data.com/ICD10CM/Codes/K00-K95/K00-K14/K02-...

Re:Suppressing a gene by using its antibody can lead to toot... by HWR_14 on Wednesday March 31, 2021 @03:04AM (#26644308)
My dentist friend claims he makes far more money per hour from cleanings than from fillings. This is because most of a cleaning is done by a relatively lowly paid hygienist but still requires him popping in for 5 minutes and a filling requires him to be there the whole time.
Re:Suppressing a gene by using its antibody can lead to toot... by kwhitefoot on Wednesday March 31, 2021 @04:07AM (#26644648)
That's really strange. Here in Norway I visit a dentist roughly once a year and usually only see my dentist if the dental hygienist has found a problem.
Re:Suppressing a gene by using its antibody can lead to toot... by HWR_14 on Thursday April 01, 2021 @11:19AM (#26661552)
5 minutes may be a bit long for the US. I don't know if it's a legal requirement that the dentist pop in (to supervise) or because people will balk at paying as much without a Doctor appearing. I'm not aware of the dentist usually finding things that the hygienist missed.
Re:Suppressing a gene by using its antibody can lead to toot... by xenadu02 on Wednesday March 31, 2021 @03:26AM (#26644411)
My dentist simply put me on toothpaste with high fluoride (IIRC 8%?). Two caries remineralized over the span of about a year and I didn't need fillings.

Unfortunately high fluoride toothpastes require an RX.

Re:Suppressing a gene by using its antibody can lead to toot... by kristofferR on Friday April 02, 2021 @03:49AM (#26669733)
I just take fluoride pills after brushing in the evening. Common here in Norway a least. Tastes great too, it's like a small treat before bedtime.

Has worked great, have never had a cavity.

Re:Suppressing a gene by using its antibody can lead to toot... by ClumsyPilot on Wednesday March 31, 2021 @05:41AM (#26645228)
Whats an RX?
Re:Suppressing a gene by using its antibody can lead to toot... by zeta0134 on Wednesday March 31, 2021 @05:51AM (#26645290)
For some reason, that's short for "prescription."

English is weird.

Re:Suppressing a gene by using its antibody can lead to toot... by monocasa on Wednesday March 31, 2021 @06:19AM (#26645476)
Well, Latin. It's short for 'recipere'.
Re:Suppressing a gene by using its antibody can lead to toot... by raducu on Wednesday March 31, 2021 @08:25AM (#26646303)
I've had multiple dentists(including my wife) tell me not to work on certain small cavities, or to use sensodyne.

Some have been under observation for more than 20 years.

I'm also sure they have re-mineralization treatments they do on site, if it was really worth it, they'd be glad to take your money for that.

I'm sure they have exact procedures for when to work on a cavity or not.

Re:Suppressing a gene by using its antibody can lead to toot... by Duckey on Tuesday March 30, 2021 @11:19PM (#26643159)
Interesting, I knew of someone who also claimed they reversed a cavity by focusing on oral care, and drinking a ton of milk.

Personally, I had a chipped tooth in my early teens and it went away after a decade. I was also drinking about a gallon of milk a day, but I don't know if that's what really fixed my tooth. I wasn't actively doing anything special with my teeth to try to fix them. I just really like milk. The problem just seemed to go away on its own.

Re:Suppressing a gene by using its antibody can lead to toot... by rexf on Wednesday March 31, 2021 @03:02AM (#26644291)
> Listen to your dentist you trust

Sure, but it's tough to find a dentist since:

> most dentists optimise for billable revenue

I find it hard to trust dentists since they may exaggerate cavities to put money in their pocket.

Re:Suppressing a gene by using its antibody can lead to toot... by wmeredith on Wednesday March 31, 2021 @04:36PM (#26652807)
> Cavities, on the other hand can be arrested (stopped), and if small can even be remineralised. Yes, most dentists don't tell you that!

What is with this sentiment about evil dentists wrecking peoples' teeth prevalent in this thread? Any dentist will tell you that if you brush and floss daily and consume sugar responsibly, that your teeth will be healthy and happy for the vast majority of your life. A VERY small percentage of the population actually does this.

There is no big dental conspiracy to destroy our teeth. We do that just fine on our own.

Re:Suppressing a gene by using its antibody can lead to toot... by throwaway57832 on Wednesday March 31, 2021 @02:33AM (#26644136)
> It's so sad that most dentists optimise for billable revenue

I've heard this so often as well as the more general statement that doctors optimize for revenue. I think it's nonsense and even dangerous. People are more likely to die from deadly diseases like cancer because they avoid doctors. The anti-vaccination movement is also very likely linked to this sentiment.

> Cavities, on the other hand can be arrested (stopped),

If they are really small. And even if, teeth with rough surface require multiple times more effort to take care of. (So you really need to chew a lot of gum) Only exception are deep holes, those you sometimes don't want to fill so the tooth can "breathe", at least for some years IIRC.

> and if small can even be remineralised. Yes, most dentists don't tell you that!

2 out of 3 dentists told me to buy remineralization tooth paste and use it once a week. Also I'm getting urged nowadays to go twice a year for tooth cleaning including professional remineralization treatment.

Disclaimer: Not a dentist either. I think medical advice should be taken from people that have actually studied that stuff.

Re:Suppressing a gene by using its antibody can lead to toot... by tmamic on Wednesday March 31, 2021 @03:46AM (#26644515)
> optimize for revenue. I think it's nonsense and even dangerous.

As with everything, there are caveats to the kind of doctor you are talking. The key distinction is that most dentists keep the residual income: the difference between the fixed costs and income. It can be a quite large sum and high % of dentists' earnings. So a dentist has a very strong incentive to increase it. Overtreating patients is the easiest way to do it since increasing the prices is not an option due to competition.

Who isn't keeping the residual income? It's the doctors who work only for a fixed salary. They can't earn more by overtreating. In fact, if they have less work, they are at profit since their salary is fixed. They don't care about increasing the residual income since they don't get it.

So, this is not some conspiracy theory. It is based on economic facts. I've analyzed this in more details here: https://documentation.denther.com/docs/industry/inefficienci...

Re:Suppressing a gene by using its antibody can lead to toot... by airhead969 on Wednesday March 31, 2021 @01:44AM (#26643910)
Orthopedic surgeons do the same thing. Inject steroids repeatedly, degrading joints in order to do joint replacements. And those joint replacements aren't great, so they need to be replaced periodically.