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Re:mRNA's next challenge: Will it work as a drug? by anonymouse008 on Friday December 18, 2020 @08:27PM (#25474129)
You’re going to tell me building random proteins in a persons body is not a Faustian Bargain?
Re:mRNA's next challenge: Will it work as a drug? by isoprophlex on Saturday December 19, 2020 @01:30AM (#25475560)
Your body constructs "wrong" proteins all the time due to translation or folding errors.

It depends on the function of the protein if this leads to a bad outcome.

Re:mRNA's next challenge: Will it work as a drug? by anonymouse008 on Saturday December 19, 2020 @02:18AM (#25475763)
Exactly — and I rely upon the many hundreds of thousands of years of experience and direct “winning” to beat adversaries.

This statement cuts both ways — if this recent pandemic was human made we need human solutions... only IF the virus is insurmountable.

As someone with direct experience with a large N, this virus is nothing to exponentially increase long term and second order risk with human “solutions” ... UNLESS the long term effects for asymptomatic cases are severe and under reported.

Again... too many variables outstanding to be certain, but highly cautious

Re:mRNA's next challenge: Will it work as a drug? by Filligree on Friday December 18, 2020 @09:29PM (#25474437)
Viruses do it all the time. It can indeed cause trouble, but a random mutated rhinovirus is more likely to do so (allergies, typically) than a vaccine which was developed specifically to not cause any damage.
Re:mRNA's next challenge: Will it work as a drug? by schoen on Saturday December 19, 2020 @01:06AM (#25475474)
This xkcd from last week is about precisely this issue! https://xkcd.com/2397/
Re:mRNA's next challenge: Will it work as a drug? by anonymouse008 on Saturday December 19, 2020 @01:51AM (#25475649)
We think way too highly of ourselves as a species
Re:mRNA's next challenge: Will it work as a drug? by anonymouse008 on Friday December 18, 2020 @09:50PM (#25474533)
I’ll fight natural selection any day... crispr, no way.

We are not gods. At least with previous vaccines we just killed off the active parts and said “hey, go bull fight this” to our immune system.

Last bit: Leverage works in both ways

Re:mRNA's next challenge: Will it work as a drug? by emsy on Friday December 18, 2020 @10:57PM (#25474872)
Organism evolves the capabilities to understands diseases and develops ways to fight them, if that isn’t natural selection what is?
Re:mRNA's next challenge: Will it work as a drug? by m4eta on Saturday December 19, 2020 @02:11AM (#25475735)
This idea that "We are not gods." Such a peculiar argument. If something is capable by a mortal man what makes you think it has god-like qualities? To me it is the opposite. Also since you're using the word "gods" are you referring to polytheism? Where did you decide you were capable of determining a "god-like" thing? You. Are. Confusing. Me.
Re:mRNA's next challenge: Will it work as a drug? by m3kw9 on Friday December 18, 2020 @09:23PM (#25474417)
Prob a safety req foe most work or travel. You gonna need one or another.
Re:mRNA's next challenge: Will it work as a drug? by chrisco255 on Friday December 18, 2020 @11:19PM (#25474979)
Sorry. No that's a violation of HIPAA and basic human rights.
Re:mRNA's next challenge: Will it work as a drug? by vkou on Saturday December 19, 2020 @12:09AM (#25475242)
Being a vector of a deadly infectious disease, and not taking basic precautions infringes on the human rights of people around you.

Anti-vaxxers are generally tolerated until there's a critical mass of them, which start causing problems for everyone else.

Re:mRNA's next challenge: Will it work as a drug? by chrisco255 on Saturday December 19, 2020 @01:54AM (#25475665)
No it doesn't. Viruses have been around longer than humans have, so NOTHING HAS CHANGED. We have been through SMALLPOX, TUBERCULOSIS, SPANISH FLU, PLAGUE, AIDS, and many, many other pandemics and NEVER, EVER has anyone been insidious enough to suggest a vaccine as a prerequisite for human rights. You need to reevaluate your logic and life choices. This disease already has a 99.9% survival rate for the general population and much higher in certain demographics.

At any rate, government tyranny has killed millions and millions more than viruses have. And I won't stand for it. Medical tyranny will never be tolerated. If YOU want the vaccine, you get it. That's how liberty works.

Re:mRNA's next challenge: Will it work as a drug? by blackbear_ on Saturday December 19, 2020 @05:25AM (#25476510)
Uhm, the Spanish flu infected 500 million people (6.5 times more than covid19) and killed about 50 million (33 times more than covid19). And if you consider that the world at that time had just about 2 billion people, a modern Spanish flu would have killed 175 million people (100 times more than covid19), and probably more since denser population makes it easier for viruses to spread.

Now, we have the (repeatedly) proven ability to avoid such a disaster, and you argue we should not? You really think protection from disease is not a basic human right?

Re:mRNA's next challenge: Will it work as a drug? by anonymouse008 on Saturday December 19, 2020 @01:59AM (#25475689)
It feels like screaming into the void
Re:mRNA's next challenge: Will it work as a drug? by useragent86 on Saturday December 19, 2020 @02:56AM (#25475898)
I've mostly given up on HN as a forum for free discussion, because the mods' endorsement of downvote-for-disagreement results in comments like yours (reasonable, historically informed, advocating liberty and actual human rights) being downvoted to obscurity, while the comments full of manipulative, Orwellian word games ("You don't want to take a vaccine? You're refusing basic precautions and infringing upon my human rights!") are prized.

So, while I used to write comments like yours, myself, I don't bother anymore. I'd have to spend years toeing the line to build up enough karma to not get shadowbanned for it.

Anyway, I sign in here to say that I'm with you. I think it's important to show that this point of view is not the minority view in this country, and maybe even the world, despite all the media does to make it look like it is.

It looks like China's already started World War 3 in terms of "Unrestricted Warfare" (China's term, not mine): financial, biological, psychological, political. Just regarding COVID, they told the world COVID wasn't infectious between people, they held a 40,000-person potluck dinner in Wuhan while the virus was spreading and then let people travel out of the city, they threatened to turn ships around and withhold masks and medicine produced in China...how can anyone look at what China's done and not recognize their malicious intent? At the same time, they're building up their military around the world, indebting poor African nations, pushing their troops into Nepal and India (and actually killing Indian soldiers)...the list goes on and on. We have to wake up before it's too late.

[Of course, the 50 Cent Army is active on HN. Watch my comment fade away...]