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Re:Link between inflammation and mental sluggishness shown i... by TurkishPoptart on Wednesday November 27, 2019 @04:26PM (#21652278)
What's the solution? I've felt brain fog for 15 years.
Re:Link between inflammation and mental sluggishness shown i... by AnimalMuppet on Wednesday November 27, 2019 @06:05PM (#21653062)
Without going to a "name brand" diet (keto, vegan, or whatever), just pay attention to what you eat and what your brain feels like a few hours afterword. I found some foods (certain chocolates, unfortunately) where, somewhat less than an hour after I ate it, it felt like someone had kicked my brain.

When you notice something like that, stop eating it. You may be able to add it back in small quantities later, but for now, just stop.

When you've identified the major ones and stopped eating them, then take stock of where you are. Is it enough? Or do you want to go further?

We started being very careful what we eat because one of my daughters had extreme food sensitivities. I said "Nah, not me, I'm good". But I felt a lot better/less mentally foggy as well.

Re:Link between inflammation and mental sluggishness shown i... by loceng on Wednesday November 27, 2019 @04:42PM (#21652404)
Ketogenic (including carnivore) diet will greatly reduce inflammation. You'll also want to do an Igg food sensitivity test to see what specific foods your body is creating inflammatory markers for, and a microbiome test can also let you know if bacterial/yeast infections that could be adding to brain fog.

Fasting is useful for seeing how your mental state is while limiting external food resources (you're using internal fat reserves otherwise), otherwise intermittent fasting is the best option.

Re:Link between inflammation and mental sluggishness shown i... by OneGuy123 on Wednesday November 27, 2019 @04:49PM (#21652485)
It seems that in practice the issue is not keto vs vegan vs omnivore but that all of those proponents of extreme diets like full vegan or full carnivore usually measure their food intake carefully to ensure they get enough of all macros (carbs, fat, protein).

This measuring alone ensures that they get enough fats, which seem to be the main reason for brain fog in most people (combined with too much artifical sweets).

Also because of this extreme diet they completely throw all all processed food & artifical sugar/sweets.

Re:Link between inflammation and mental sluggishness shown i... by loceng on Wednesday November 27, 2019 @05:56PM (#21652993)
You're close to right. The "vegan honeymoon" - as an example - is an example of why many people will feel better cutting out bad foods, however carbohydrates and sugars are some of the largest inflammatory factors from my understanding, so cutting that out will help. Following vegan or omnivore doesn't mean eating a balanced (carbs, fat, protein) diet nor anti-inflammatory, doesn't mean eating a diet specifically that is healthy for your body either - doesn't remove foods you may individually be sensitive to.
Re:Link between inflammation and mental sluggishness shown i... by tayo42 on Wednesday November 27, 2019 @09:42PM (#21654216)
Fasting would just make me irritable and hungry. I don't think I'm the only one that would experience that
Re:Link between inflammation and mental sluggishness shown i... by kranner on Wednesday November 27, 2019 @11:35PM (#21654607)
You get used to it remarkably quickly. The problem is getting over the hump (and also, knowing there is a hump).

Buddhist monks are not supposed to eat after noon, although some cheat by adding a lot of sugar to their evening tea or coffee. This is supposed to keep their minds sharp and clear and aid in meditation. It appears to be a well-tested rule.

Re:Link between inflammation and mental sluggishness shown i... by asterix_pano on Thursday November 28, 2019 @04:34AM (#21655823)
Are animal proteins not a source of inflammation? It's quite well studied.
Re:Link between inflammation and mental sluggishness shown i... by virtuallynathan on Thursday November 28, 2019 @02:54PM (#21659790)
Nope, not in free living humans.
Re:Link between inflammation and mental sluggishness shown i... by zadler on Wednesday November 27, 2019 @09:36PM (#21654195)
Seems like IGG doesn’t have the best reputation...
Re:Link between inflammation and mental sluggishness shown i... by loceng on Thursday November 28, 2019 @04:29PM (#21660310)
Just like fat didn't have a good reputation for awhile due to X, Y, Z - be weary of your sources.

I use my own experience with Igg food sensitivity testing and removing those foods to see how I felt after. After allowing my system to calm from the foods then reintroducing just one of the foods that I was conditioned to the discomfort of, it let me see how much discomfort/pain different foods that showed up on the Igg test that make me feel horrible.

Re:Link between inflammation and mental sluggishness shown i... by virtuallynathan on Thursday November 28, 2019 @02:54PM (#21659793)
Correct, these tests are mostly useless.
Re:Link between inflammation and mental sluggishness shown i... by djohnston on Wednesday November 27, 2019 @06:01PM (#21653037)
Obviously this is anecdotal, but I've been fasting for about a month, and I've noticed a significant difference between the days I fast and the days I don't (FRIDAYS!!!). After about 16-18 hours of not eating I feel quite sharp. There seems to be preliminary clinical evidence to support this, but I'll leave the googling to you.
Re:Link between inflammation and mental sluggishness shown i... by jfrbfbreudh on Wednesday November 27, 2019 @08:48PM (#21654006)
I’ve had the same experience, but feeling sharper doesn’t mean actually being sharper. If you look at traffic accident rates in Muslim majority countries, there’s a sharp rise in incidents during the fasting months of Ramadan.
Re:Link between inflammation and mental sluggishness shown i... by handedness on Wednesday November 27, 2019 @09:00PM (#21654052)
Ramadan involves a number of societal changes beyond just not eating during daylight hours, from fasting to abstinence to busier public squares and restaurants. I'd want to see something control for the differences in movement patterns, passenger miles driven, meals eaten outside the home vs. at home, and so on. Public squares and restaurants are typically packed during Ramadan at night.

Here's one (theoretically) similar example:

https://www.datagraver.com/case/relation-terrorism-attacks-a...

Re:Link between inflammation and mental sluggishness shown i... by kranner on Wednesday November 27, 2019 @11:32PM (#21654593)
Fasting during Ramadan is not the same as IF at all. During Ramadan you can't have even a sip of water, whereas in IF you are encouraged to drink water and even add a bit of salt if needed. That alone makes them too different to compare effects.
Re:Link between inflammation and mental sluggishness shown i... by jfrbfbreudh on Thursday November 28, 2019 @12:31AM (#21654828)
That’s a very good point and not something I had considered. Still, I am curious as to how the feeling of sharpness translates to actual performance.
Re:Link between inflammation and mental sluggishness shown i... by emmanuel_1234 on Thursday November 28, 2019 @02:39AM (#21655345)
The most obvious culprit is the lack of sleep, since feeding can only be done at night.
Re:Link between inflammation and mental sluggishness shown i... by alpaca128 on Wednesday November 27, 2019 @06:51PM (#21653366)
I've experienced similar effects with intermittent fasting. I started cutting out the breakfast and after a while my mind was super clear in the morning. Eating lunch caused that to flip around drastically, though.
Re:Link between inflammation and mental sluggishness shown i... by matwood on Wednesday November 27, 2019 @09:11PM (#21654100)
I'm glad you mentioned IF. It's one of the easier ways to get many of the keto benefits without having to do keto.
Re:Link between inflammation and mental sluggishness shown i... by ScoobleDoodle on Wednesday November 27, 2019 @06:37PM (#21653266)
Unrelated to diet but still could be helpful with brain fog: Have you ever been tested for sleep apnea? I was diagnosed with severe sleep apnea over a decade ago and was prescribed a CPAP machine. Although it took some getting used to. Getting effective sleep has helped me.
Re:Link between inflammation and mental sluggishness shown i... by bitL on Wednesday November 27, 2019 @08:58PM (#21654044)
I use sauna; 10-15 minutes in hot, followed by a short break (1-2 minutes), then up to 2 minutes immersed in cold water. Repeat 5-6x. I feel like a new person afterwards, total mental clarity and many ideas immediately. Also removes stress. It might take you a few months to get adapted to that cycle though (2-minute cold immersion is not trivial at first). If you start feeling bad, abort, you can try next time.
Re:Link between inflammation and mental sluggishness shown i... by thomk on Wednesday November 27, 2019 @10:27PM (#21654380)
This is no joke. After a shower, I turn off the hot water and just stand there under the cold water for a while. It makes a big difference for me. So does not eating late.
Re:Link between inflammation and mental sluggishness shown i... by Buttons840 on Wednesday November 27, 2019 @09:13PM (#21654107)
If knowingly taking a placebo can affect a person, I have no doubt that the ritual you described can also have an effect.
Re:Link between inflammation and mental sluggishness shown i... by friendlybus on Wednesday November 27, 2019 @10:11PM (#21654324)
Heat shock forces some cells or proteins to rejuvenate themselves. Dr Rhonda Patrick and the anti-aging guy have talked about similar ideas for hours in depth on joe rogan's podcast but I never remember the details in full.
Re:Link between inflammation and mental sluggishness shown i... by sharedfrog on Thursday November 28, 2019 @03:49AM (#21655644)
> the anti-aging guy

Aubrey de Grey?

Re:Link between inflammation and mental sluggishness shown i... by friendlybus on Thursday November 28, 2019 @11:24PM (#21662036)
David Sinclair
Re:Link between inflammation and mental sluggishness shown i... by bitL on Thursday November 28, 2019 @05:59AM (#21656223)
This came from trial and error from about 6 months of trying different things in sauna. Just heating myself multiple times in hot sauna didn't work that well, but once I started to rigorously follow >1 minute cold water immersions, after 3-4x cycles I almost always ended up in a stress-less state of mental clarity (not when I felt bad/sick or didn't sleep well though). After ~4 cold immersions I also look like my skin was full of veins, connected red patches over white patches everywhere. YMMV
Re:Link between inflammation and mental sluggishness shown i... by DenisM on Wednesday November 27, 2019 @07:39PM (#21653689)
Before trying various changes which takes a long time to se through consider measuring things you can actually test:

1. Sleep study.

2. Vitamin D blood test.

3. Generally a conversation with your doctor who might suggest other tests.

Re:Link between inflammation and mental sluggishness shown i... by mixmastamyk on Wednesday November 27, 2019 @04:29PM (#21652298)
Look into reducing inflammation. There are a number of foods that are supposed to be beneficial. I believe avoiding corporate grain products may also help.
Re:Link between inflammation and mental sluggishness shown i... by MrBuddyCasino on Wednesday November 27, 2019 @06:48PM (#21653349)
Keto worked for me. The difference is remarkable.
Re:Link between inflammation and mental sluggishness shown i... by flybrand on Wednesday November 27, 2019 @08:20PM (#21653877)
It was another set of symptoms - skin rash like chicken pox - that helped me find my celiac / gluten free diagnosis.

However, the brain fog went away. Brain fog is a common reason people try gluten free or low carb (keto, Meng, etc).

Good luck.

Re:Link between inflammation and mental sluggishness shown i... by nimvlaj30 on Wednesday November 27, 2019 @07:44PM (#21653717)
I would try intermittent fasting for a while. If you feel better, it means it could be exacerbated by something you're eating. Then it's a just a process of elimination.
Re:Link between inflammation and mental sluggishness shown i... by Cougher on Thursday November 28, 2019 @06:40AM (#21656450)
One thing would be to get rid of as many fragranced products as you can. It's amazing how many people live 24/7 without ever truly breathing fresh air. This would be especially had with fragranced dryer sheets, as the residual fragrance will last through many washings. New mattresses are also notoriously toxic.
Re:Link between inflammation and mental sluggishness shown i... by m463 on Wednesday November 27, 2019 @07:23PM (#21653601)
nobody has mentioned exercise.

I remember the study with the "rats in a sterile environment" vs "rats in a rich environment" where the latter group formed many more brain connections.

In the end, they found it wasn't the rich environment that caused the brain growth, it was the exercise wheel in it.

Re:Link between inflammation and mental sluggishness shown i... by Bizarro on Wednesday November 27, 2019 @07:30PM (#21653646)
Be careful with the exercise remedy. It's easy to overdue it and cause more inflammation and stress via elevated cortisols, etc..
Re:Link between inflammation and mental sluggishness shown i... by Broken_Hippo on Wednesday November 27, 2019 @06:18PM (#21653154)
talk to a doctor and, if you are lucky, they find something they can cure. If you are unlucky, they find nothing. If you are really unlucky, you find something like an autoimmune disorder - lots of autoimmune disorders get both some inflammation and 'brain fog' or other cognitive issues.

All the diets folks recommend are not really proven to help with things like autoimmune disorders (even though some folks swear by them). If it were that simple, it would be standard treatment and no one would go through the side effects that some of the medicines for autoimmune disorders have. I don't know how effective the diets and supplements are for other things, but I'd not trust it unless it came from the mouth of a medical doctor I trusted.

Re:Link between inflammation and mental sluggishness shown i... by MrBuddyCasino on Wednesday November 27, 2019 @06:53PM (#21653375)
No. Docs have no clue about these sort of things. They are good for "leg broken, must fix leg". They suck at chronic and ambiguous illnesses. In the US, you can try the Mayo Clinic, they have specialists. Otherwise, help yourself.
Re:Link between inflammation and mental sluggishness shown i... by Bizarro on Wednesday November 27, 2019 @07:29PM (#21653635)
Unfortunately, that's really true. I have a doctor friend that looked at me like a deer in headlights when I asked about fatigue, brain fog, inflammation, food sensitivities, etc..
Re:Link between inflammation and mental sluggishness shown i... by Broken_Hippo on Thursday November 28, 2019 @09:19AM (#21657517)
Because.. internists don't exist as primary care doctors? Because the start of getting diagnosed with chronic illnesses doesn't start with a primary care doctor?

OR because insurances and governments aren't interested in not spending thousands of dollars per month per patient on autoimmune medicines when a simple diet change could do the same thing?

There are more players than doctors. Folks go to specialists all the freaking time for their disorders, but not all disorders need that. You'll probably be just fine going to the normal doctor for type II diabetes. You'll probably go to a neurologist for your MS. Not all disorders need something like the Mayo Clinic. When we suck, we simply suck and that includes the Mayo Clinic and similar clinics.

None of this changes the fact that there isn't evidence that diet helps in the long run for a lot of disorders. Staying generally healthy helps, sure, but saying anything else dupes folks into trying a bunch of weird, non-approved things and buying into snake oils.

Re:Link between inflammation and mental sluggishness shown i... by MrBuddyCasino on Thursday November 28, 2019 @02:47PM (#21659756)
> Staying generally healthy helps

Its that easy huh. I'm afraid you got it exactly backwards. Snake oil is the last resort of people who are not being helped by the medical system. People don't love going from one doc to another, being told that "its probably psychological". Countless tests are not great even if they don't bankrupt you. I'm not saying its easy! Most doctors aren't even remotely trained for this, and they don't have the time per patient. Its a difficult task.

What we need are special doctors for chronic diseases. There is a department at a German university (Heidelberg I think), which is being subsidised by the other things they do. They have good successes, helping people that could not be helped for years, but the waiting list is very very very long.

Re:Link between inflammation and mental sluggishness shown i... by Broken_Hippo on Thursday November 28, 2019 @04:44PM (#21660381)
Generally healthy: You can have a chronic disease and work on being generally healthy. Eat a varied diet. Exercise as you can. Don't smoke. I should mention at this point that I have a chronic disease - MS. There is no cure. But all that stuff helps people's outcome. The special diets do not.

There are special doctors for some chronic diseases - like MS. Most folks go to a normal neurologist, and a few are lucky enough to have some specialists near them. I have nurses that are specialized that I see more than the neurologist as it helps the neurologist see more folks.

That said, not all chronic diseases and conditions need a specialist. Type 2 diabetes is a chronic condition. High blood pressure is a chronic condition (and not always caused by diet/exercise). Depression is chronic. The thing is that some of these are common enough that it is pretty easy for a doctor to know about them. If you are lucky, you see an internist, who specialises in adult general medicine.

Not all chronic diseases and conditions are things that are puzzling either. There is no reason for most folks to see these sorts of specialists, but I wish they were more available for folks that need them. This is a pretty slim portion of patients, though. Some diseases we don't know much about, and we need science to help. I've donated spinal fluid to help things along and I'll donate my body to science after whatever organ donation they'll let me do. I urge others to do similar stuff, and this is why I both want medical records digital and want them to be searchable by researchers. For everyone that doesn't specifically opt out, anyway.

Most of the tests you mention? Yeah, if you are going to see a specialist, they are going to do the tests. Medicine is a profession of puzzles. You take vague symptoms that could have many causes and do tests to rule things out.

Re:Link between inflammation and mental sluggishness shown i... by rorykoehler on Wednesday November 27, 2019 @11:56PM (#21654680)
I have conclusive evidence (sample size 1)that keto reduces inflammation from my AS. The blood tests don't lie but its far from being a cure.
Re:Link between inflammation and mental sluggishness shown i... by belltaco on Wednesday November 27, 2019 @11:52PM (#21654665)
Curcumin supplements and/or consuming a lot of turmeric with a little pepper can help.
Re:Link between inflammation and mental sluggishness shown i... by virtuallynathan on Thursday November 28, 2019 @02:56PM (#21659799)
No randomized clinical trials of curcumin have shown benefit. Fixing the source of the inflammation is a better idea than taking anti-inflammatory compounds of dubious benefit.
Re:Link between inflammation and mental sluggishness shown i... by belltaco on Thursday November 28, 2019 @04:54PM (#21660440)
Re:Link between inflammation and mental sluggishness shown i... by lambdaba on Wednesday November 27, 2019 @06:10PM (#21653103)
High (10g+) doses of omega-3 (mostly as EPA) are extremely effective and clinically proven.

Standard doses are way too small to be effective, and most of the science and anecdotes refer to small (1-3g) doses.

Re:Link between inflammation and mental sluggishness shown i... by Asooka on Wednesday November 27, 2019 @06:49PM (#21653351)
I had vitamin D deficiency that was the cause of my brain fog. I'm not yet back to full power, but the last 3 months of taking it have definitely been better than before.
Re:Link between inflammation and mental sluggishness shown i... by OneGuy123 on Wednesday November 27, 2019 @04:34PM (#21652337)
I've had issues like that:

Buy hydrolyzed collagen supplements (take 30g per day at start for 1 week) and increase fat intake, simplest is beef tallow (ideally grassfed), eat 2x 5 table spoons of it per day for 5 days at start.

And cut all processed sugar and sweets.

Replace table sugar and fructose with glucose.

Re:Link between inflammation and mental sluggishness shown i... by kyuudou on Wednesday November 27, 2019 @10:07PM (#21654313)
A whole (organic) chicken in a pot, cooked until the cartilage liquefies, is similar to this suggestion IMO
Re:Link between inflammation and mental sluggishness shown i... by viburnum on Thursday November 28, 2019 @12:11AM (#21654746)
I stopped eating anything with added sugar and my brain fog lifted after about a week. Now I get headaches if I eat sugar (Berries are good, it’s just stuff with sugar added to it that messes me up).
Re:Link between inflammation and mental sluggishness shown i... by goodname on Wednesday November 27, 2019 @06:30PM (#21653234)
Have you been tested for celiac disease?