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Re:Statisticians want to abandon science’s standard measure ... by TallGuyShort on Friday September 06, 2019 @09:27AM (#20895409)
The problem isn't p-values, the problem is a binary distinction between p=0.049 and p=0.051. The problem would go away if everyone understood p-values, or we replaced use of the term "statistically significant" with "3% probability we're just seeing a pattern by accident". Renaming the term to something that sounds just as binary isn't any different.
Re:Statisticians want to abandon science’s standard measure ... by krcz on Friday September 06, 2019 @09:56AM (#20895655)
It's worth to point that "3% probability we're just seeing a pattern by accident" is only right when you understand it as "in the world here our hypothesis is wrong the same experiment would give such pattern in 3% cases", not as "given such result probability that we are wrong is 3%".
Re:Statisticians want to abandon science’s standard measure ... by onlyrealcuzzo on Friday September 06, 2019 @10:45AM (#20896096)
It seems like an education fail to me. Most people don't know the very basics of stats and we live in a world that's highly probabilistic.

It seems like something that should be taught alongside math from elementary school, not something you can maybe get an elective in in high school or college.

Re:Statisticians want to abandon science’s standard measure ... by grawprog on Friday September 06, 2019 @02:56PM (#20898672)
I never learned statistics until my second year in university, it was really mind opening, especially with showing me just how much poorly done statistics with tiny sample sizes or misrepresented data are quoted and used as facts.

I actually found statistics pretty fun and eventually we learned to use R for it. Though I ended up missing 1 lecture and it almost screwed me over for the rest of the class. I found a Kahn academy video though that covered it and was able to catch up. There really is a ton of information to learn. It would have been nice to have at least touched on it a little bit in highschool beyond learning about means and the tiniest bit about standard deviations.

Re:Statisticians want to abandon science’s standard measure ... by TallGuyShort on Friday September 06, 2019 @11:10AM (#20896319)
This guy is one of my favorite TED speakers, and he makes a strong argument for exactly this: https://www.ted.com/talks/arthur_benjamin_s_formula_for_chan....
Re:Statisticians want to abandon science’s standard measure ... by susiecambria on Friday September 06, 2019 @07:28PM (#20900785)
Thanks for sharing! (writes the girl who barely passed pre-calc)
Re:Statisticians want to abandon science’s standard measure ... by DoofusOfDeath on Friday September 06, 2019 @03:01PM (#20898731)
> It seems like an education fail to me.

I know a lot of people have trouble thinking clearly and correctly about probability and statistical inference.

But do we know if, practically speaking, that can be addressed by a modified educational curriculum?

Or are these concepts that would take an extraordinary amount of effort for many persons to understand well?

Re:Statisticians want to abandon science’s standard measure ... by TallGuyShort on Friday September 06, 2019 @06:18PM (#20900391)
They're nuanced concepts that are easily misunderstood, but in a typical US public school, statistical significance (or anything beyond basic descriptive statistics) is not typically part of the curriculum[1]. It's a hard problem to effectively educate out of existence but right now we're not even really trying.

[1] source: I never saw it as a student, and I've consulted with math teachers (well, administrators, about math) in multiple states, and I've never had it come up there either.

Re:Statisticians want to abandon science’s standard measure ... by CreRecombinase on Friday September 06, 2019 @09:55AM (#20895646)
This is a a really common misconception about p values (that they can be interpreted as p(H0|x), or "probability of the null hypothesis given the data") when a p-value is in fact p(x|H0), or "probability of observing data at least this extreme given that the null hypothesis is true
Re:Statisticians want to abandon science’s standard measure ... by andrewla on Friday September 06, 2019 @02:21PM (#20898266)
This is a more mathematically precise restatement of kerkeslager's explanation below and the obligatory xkcd [1]. The problem boils down to the fact that null results are not usually published, and that intuitive skepticism is not quantifiable.

Essentially, we want to get p(H0|x), but we need Bayes Law to get this from p(x|H0). But we need some notion of what priors to use. This is of course impossible to actually get, but if we published null studies then it would allow us to estimate it with better confidence. Alternatively we can ballpark it by saying how unexpected the result is, and how long the effect being explained has been studied.

The "common-sense" version of this is intuitive, that "extraordinary claims require extraordinary evidence". The more unexpected a result is, the lower the p-value has to be to be convincing.

The epidemiological version of this shows up in things like the Bradford Hill criteria [2], which include significance of association but also attempt to bring in plausibility.

[1] https://xkcd.com/882/

[2] https://en.wikipedia.org/wiki/Bradford_Hill_criteria

Re:Statisticians want to abandon science’s standard measure ... by CreRecombinase on Friday September 06, 2019 @05:09PM (#20899926)
I'd argue that p(H0|x) is also (in most cases) pretty uninteresting from a scientific perspective, and so the whole "publish all the p-values" solution I think is only fighting half the battle. Gelman does a much better job of arguing this than I ever could [1], but this idea that rejecting the null is the "desired" outcome is the real problem. To put it another way, a low p-value is another way of saying "my model of the data generating process is bad", which is in most cases a pretty unsatisfactory outcome. As to the idea that priors are "impossible" to get, to quote Gelman [2] again, why "strain at the gnat that is the prior and swallow the ungainly camel that is the iid likelihood?

[1] https://statmodeling.stat.columbia.edu/2015/03/02/what-hypot... [2] https://statmodeling.stat.columbia.edu/2015/07/03/why-should...

Re:Statisticians want to abandon science’s standard measure ... by TallGuyShort on Friday September 06, 2019 @11:13AM (#20896340)
Do you have a better of wording for inclusion in paper abstracts / article summaries than what I said? I'd love to hear one, but p(x|H0) is just as bad as p = 0.05.
Re:Statisticians want to abandon science’s standard measure ... by SquishyPanda23 on Friday September 06, 2019 @11:40AM (#20896624)
The problem isn't that the wording is confusing, it's that p(x|H0) isn't a very useful thing to compute.

Everybody wants to compute p(H|x), the probility of a scientific hypothesis given the data. People want to do this so badly that they can't help interpreting the p-value that way.

You can actually compute p(H|x) if you use Bayesian stats.

Re:Statisticians want to abandon science’s standard measure ... by CrazyStat on Friday September 06, 2019 @11:55AM (#20896776)
With some caveats: the value you get for P(H|x) might be very sensitive to the priors you choose, and most people are not thoughtful enough about this.
Re:Statisticians want to abandon science’s standard measure ... by SquishyPanda23 on Friday September 06, 2019 @03:11PM (#20898816)
Yes that is true, but there is a sense in which that just makes explicit a problem that already exists.
Re:Statisticians want to abandon science’s standard measure ... by andrewla on Friday September 06, 2019 @02:23PM (#20898286)
> You can actually compute p(H|x) if you use Bayesian stats.

You can't "compute" it for any useful meaning of the word "compute". You can estimate it intuitively, or you can try to look at how many pre-registered unpublished studies or null results have been published. Otherwise there's no way to even consider getting a grasp of what P(H) would be.

Re:Statisticians want to abandon science’s standard measure ... by hervature on Friday September 06, 2019 @04:01PM (#20899367)
> Otherwise there's no way to even consider getting a grasp of what P(H) would be.

That's called picking a prior. Usually, pick the prior that maximizes the entropy on the given interval (zero prior knowledge).

For those reading and confused. Computing: p(H|x) = p(x|H)p(H)/p(x)

requires p(H) which the parent is suggesting is impossible to grasp.

If we want to know the probability that a coin is biased, we can assign probabilities to each hypothesis. For some people, p(bias=1/2)=1 (Dirac distribution), others might argue that p(bias=x)=1 for x in [0,1] (uniform distribution). Others might argue its some Beta function centered around 1/2. I believe what the parent is suggesting is that choosing which original belief we have in the system is a matter of philosophy, not computation.

Re:Statisticians want to abandon science’s standard measure ... by pfortuny on Friday September 06, 2019 @01:22PM (#20897616)
Wait wait wait: you need the priors, also. Where do they come from?
Re:Statisticians want to abandon science’s standard measure ... by SquishyPanda23 on Friday September 06, 2019 @02:48PM (#20898601)
That's definitely the hard part of switching to Bayesian methods. But the problem doesn't go away if you use p values, it just gets ignored.

Typically people doing research have prior information about what they are researching. E.g. previous studies have found effect sizes to be in some interval.

You can fallback on an uninformative prior or other tricks if you really want to model the idea that you know literally nothing about what you're researching. But that should be very rare.

Re:Statisticians want to abandon science’s standard measure ... by NohatCoder on Friday September 06, 2019 @02:59PM (#20898704)
You just make priors up, just like the 0.05 limit is made up. Making up a prior is basically asking the question: How likely does it seem that X has Y effect? Without having any data specific to that question.

Our 0.05 p-value limit is effectively just answering that question with a fixed 5%, no matter how ridiculous the proposition is.

Re:Statisticians want to abandon science’s standard measure ... by kazinator on Friday September 06, 2019 @03:20PM (#20898943)
"Our research creates a lot of confidence that the hypothesis is true. If our hypothesis happens to be false, then only 1 in 20 independent repetitions of our research (P = 0.05) will obtain the good results that we present here."
Re:Statisticians want to abandon science’s standard measure ... by roenxi on Friday September 06, 2019 @10:25AM (#20895893)
We use hard cutoffs for a bunch of things, they aren't perfect but they are fine.

The problem is that we are imbuing the words "statistical significance" with a whole bunch of math. This would be fine, except for the inconvenient fact that people also want to use the word "significance" as it is defined in English.

It is not only possible, but likely that people will be producing results that are insignificant but statistically significant. I mean seriously, if I tell my boss that the results are statistically significant, how do I expect him to understand that the results might reasonably be insignificant? How do I expect anyone non-technical to take that sentence seriously? You lose all credibility pretty quickly when people start saying that the result is significant except it doesn't matter.

This is even more stupid than calling complex numbers "imaginary" and "complex". Those names are just arbitrary. Statistical significance is overloading words that are likely to come up with meanings other than what they are expected to mean.

Anyway, this is the problem that things like this article are going to. People are treating significance values as though they are significant. They aren't significant, they are statistically significant. It means something different to significance.

For example; if I run an experiment 20 times and get a p value consistent with a 5% chance in one experiment, it is statistically significant but the result is obviously not significant in the English-language meaning of the word.

Re:Statisticians want to abandon science’s standard measure ... by abakker on Friday September 06, 2019 @11:27AM (#20896491)
This is an excellent point. In my work, the interpretation error I see the most among people around be is to confuse significance with the magnitude of the predicted effect. I.e. if you use OLS to create a model, it is possible to have a statistically significant beta, with essentially no magnitude.

If you look at research on carcinogens, it is frequent to see something like "it is statistically significant that eating chemical X increases your risk of cancer" but when you read on, the magnitude of the effect is "increases risk by .0023%, for a cancer that already has a .6% incidence in the population".

My point is that people who are not statisticians (or people who use statistics), tend to be concerned with the magnitude of an effect, and frequently misconstrue the statistical significance for that magnitude.

Re:Statisticians want to abandon science’s standard measure ... by kerkeslager on Friday September 06, 2019 @11:15AM (#20896371)
This is a really good point.

In fact, failures to reproduce "landmark" experiments have low significance (statistics word) because they find a result that is highly probable if the null hypothesis is true. But failures to reproduce have high significance (colloquial English word) because they indicate that widely-held beliefs are wrong. So in some of the most important cases, the statistics and colloquial English meanings of the words are exactly the opposite.

I don't know if there's a good solution to this, though--it's hard to change organically-emergent trends in language even if we did come up with a better term.

Re:Statisticians want to abandon science’s standard measure ... by vharuck on Friday September 06, 2019 @03:37PM (#20899116)
I've been trying to not use the words "statistical significance" in my reports. It's hard to find alternatives, but "confident" usually fits the bill. Sadly, the reports need reviewed by other statisticians, and they much prefer I use the normal jargon because it's clearer to them.

But these concepts aren't clear to the people using the data. I've seen people use statistical tests done in batch without correcting for multiple testing (one of my regrettable tasks), and flat out ignore any differences that weren't statistically significant. They thought it meant "no difference."

With population-level data (e.g., Census counts or hospital records), I sometimes wonder if statistical significance has any value. It's a tool to make sure we don't accidentally claim a difference where there isn't one. But I can guarantee you that nothing worth measuring is exactly the same for men, women, whites, blacks, young, old, whatever. It'd be amazing if the difference was 0. So statistical significance ends up being an obfuscated way to state the sample size.

Re:Statisticians want to abandon science’s standard measure ... by raizinho on Saturday September 07, 2019 @07:33AM (#20903151)
That's why the notion of practical significance exists expressed most frequently as an effect size.
Re:Statisticians want to abandon science’s standard measure ... by btilly on Friday September 06, 2019 @12:21PM (#20896989)
I disbelieve.

The problem is that people want an answer to the question, "Here is a pile of data, what should I believe?" But mathematically, the proper role of data is to modify existing beliefs, and not to dictate beliefs.

Statisticians can spend forever explaining this. But instead have gone with the cop-out of asking a question that is confusingly similar to the one that people want to ask. It is popular exactly because it is so easily misunderstood. You can give any number of lectures on what it actually means - I guarantee that it will be misunderstood.

Worse yet, p-values are sensitive to particulars of experimental design that logically should never matter to inferences. My aunt and uncle provide a classic example. They wanted a son and a daughter. They had 6 sons then a daughter. Are they biased towards one gender? The p-value for this question is .03125 (we'd see this much evidence against with all boys, all girls, last girl, last boy, so 4/2^7). But if I instead said that they planned to have 7 children, and had 6 sons then a daughter, the p-value changes to 0.125 because the one child out could have been anywhere in succession. But in Bayes' formula, their plans if something else had happened cannot ever affect how we adjust our inferences.

(This example is not made up. When Lorna found that they had a daughter, she told Bill to get a vasectomy from the delivery table. By another crazy coincidence, their 7 children were also born on all the days of the week.)

Re:Statisticians want to abandon science’s standard measure ... by ghkbrew on Friday September 06, 2019 @12:55PM (#20897338)
> But in Bayes' formula, their plans if something else had happened cannot ever affect how we adjust our inferences

That's not how statistics works. Frequentist p-values and Bayesian inferences are both entirely dependent on the mathematical model in question. "Their plans if something else had happened" are a key part of the model. What you're describing at 2 entirely different experiments:

1) A couple has children until they have 1 of each gender. they have 7 children. How likely is a result this extreme (or greater)?

2) A couple has 7 children. They have a gender ratio of 6:1. How likely is a result this extreme (or greater)?

Re:Statisticians want to abandon science’s standard measure ... by btilly on Friday September 06, 2019 @03:10PM (#20898808)
No, that is EXACTLY how probability theory works.

The probability of event A given that we observed B is the probability of A and B happening divided by the probability that B happened. Mighta, coulda, shoulda but didn't doesn't enter into it and can't affect the result. The fact that frequentist statistics does care and shouldn't is one of the major criticisms that Bayesians offer.

If you think you understand statistics and don't understand this fact, then you do not understand statistics as well as you think you do. But you can be pardoned. Most statistics classes are too busy cramming statistical tests into student's heads to bother them with bothersome facts about where the cracks in the foundations are.

Re:Statisticians want to abandon science’s standard measure ... by RosanaAnaDana on Friday September 06, 2019 @12:33PM (#20897109)
Well, sort-of.

Its not just about p-values or the likelyhood of making a particular type of error by agreeing with a thesis.

There is a fundamental misunderstanding that most people, and even many scientists make with regards to the philosophical interpretation of 'truth' using the scientific method.

By definition, scientific 'truth' is always fallible, and the vast majority of people have a very hard time dealing with this concept. A better explanation or additional data, or better data is always possible and needs to be possible for science to not be dogma. This is fundamentally different than how people interpret truth and understand what the word means. All scientific truths are replaceable.

Re:Statisticians want to abandon science’s standard measure ... by srpguy on Friday September 06, 2019 @01:07PM (#20897454)
"You can give any number of lectures on what it actually means - I guarantee that it will be misunderstood."

So true. That said, here's a great interactive explaining the p-value: https://www.jwilber.me/permutationtest/

Re:Statisticians want to abandon science’s standard measure ... by rjf72 on Friday September 06, 2019 @01:12PM (#20897511)
I agree with you, but I think there is an even more fundamental issue. P-values really don't tell you anything. They can refute a bad hypothesis but they cannot validate a good one. This [1] is such an awesome site. It lists a large number of spurious correlations. It's quite remarkable how strong many of them are. For instance there is a 99.79% correlation between suicides by hanging and US spending on science/space/technology.

The big problem is that since we've already long since entered the world of big data you can now find spurious correlations, similarly strong, but constrained to variables that are plausibly connected. For instance what if this correlation was between spending on science/space/technology and an increase in the number of people pursuing STEM fields? People would immediately just accept it without question, even though it should in theory be held to the same scientific rigor and critique as one that challenges our biases. Science should not be a glorified exercise in confirmation bias. Spurious correlations don't mean you have a biased sample or that such correlations don't exist - it simply means that correlations have no direct relationship.

538 has a great little interactive p-hacking game you can play, with real data. [2] Ultimately any single datum that tries to legitimize a piece of research is going to be gamed. Science should be judged as it was in its 'glory days' - by the logic, predictability, and falsifiability of the ideas presented. Anything that steps outside these bounds should be treated with the most extreme of prejudice. It may be legitimate but the great burden of proof is on the presenter, and that doesn't come down to p-hacking up a 0.00001 correlation and calling it causal.

[1] - http://www.tylervigen.com/spurious-correlations

[2] - https://projects.fivethirtyeight.com/p-hacking/

Re:Statisticians want to abandon science’s standard measure ... by WhompingWindows on Friday September 06, 2019 @12:55PM (#20897336)
P-values are much more problematic at the alpha=.05 threshold than the alpha=.005 or alpha=.01 thresholds.

In my work as a data scientist, 99% of the time this is not even relevant. We have huge sample sizes and most of the p-values we see are <.0001, meaning there is SO much data that even a very very small effect size can be found "significant."

The question then: does a mean of 20.02 being significantly different from a mean of 20.03 over 10 million patients, is that actually important to us?

Re:Statisticians want to abandon science’s standard measure ... by mswen on Friday September 06, 2019 @01:28PM (#20897670)
Yes, thank you. Practical significance. You cannot get away with just running statistical test or deep learning models. You often need to ask whether a change in product, service or process to take advantage of some trend or difference between customers segment will actually be worth doing. That involves getting your hands dirty in the business, trying to identify all the costs and side-effects of a change, and then how much of a size effect you will actually capture once the changes are made. My views in more detail [1]

[1] http://computationalimagination.com/article_practical_signif...

Re:Statisticians want to abandon science’s standard measure ... by jredwards on Friday September 06, 2019 @07:16PM (#20900727)
While I agree with that completely, the coinciding problem that I've run into time and time again is the temptation to accept statistical significance but ignore the size of the effect.

You might see p=0.00001 but if the size of the effect irrelevant, then the statistical significance of the relationship is still not something I care about. Great, orange juice shrinks tumors by 0.000001%. I'm still going with chemo, thanks.

Re:Statisticians want to abandon science’s standard measure ... by tschwimmer on Friday September 06, 2019 @07:04PM (#20900650)
I think this is part of the problem, but the more fundamental issue is that people are extremely bad about probabilistic reasoning. Even if we said "3% probability we're just seeing a pattern by accident" most people unconsciously round this down to zero.

People that work with computers often are slightly better about reasoning about probabilities because they often deal with high frequency events. A 1% error rate across 10 million events a day leads to 100,000 errors. If those events are transactions, payments, file uploads etc, a 1% chance starts to look very common. But even computer people are not immune to incorrectly reasoning about probabilities. I suspect there is some fundamental limitation at the cognitive level.

Re:Statisticians want to abandon science’s standard measure ... by analog31 on Friday September 06, 2019 @06:48PM (#20900568)
I have a rule of thumb: Multiply p by 10. In other words, p = 0.05 is as good as a coin toss. This is consistent with the so called replication crisis.

In my view, understanding p-values won't help. Feeding data into a formula that produces a p-value doesn't account for things that can go wrong with experiments: Uncontrolled experimental conditions, biased sampling, hidden correlations, and simply non-ergodic systems. It is possible that some systems can't be controlled to the point where it's reasonable to start looking for real effects.

I suspect that if the results were any good, the precise interpretation of the p-value wouldn't matter. Physics has lived without an agreed-upon interpretation of quantum theory for a century.

Re:Statisticians want to abandon science’s standard measure ... by ludamad on Friday September 06, 2019 @10:23AM (#20895872)
"3% probability we're just seeing a pattern by accident" in fact still sounds a lot better than it is if there is a positive result bias, as you'll miss the "but 99 percent of scientists who attempted this did not see a pattern"
Re:Statisticians want to abandon science’s standard measure ... by platz on Friday September 06, 2019 @11:25AM (#20896473)
At the end of the day, people need to make a decision about something, and I suspect this is what is forcing the importance of this binary distinction.

My decision to select, implement, go, or no go cannot itself be a probability distribution.

Re:Statisticians want to abandon science’s standard measure ... by TallGuyShort on Friday September 06, 2019 @11:27AM (#20896485)
Decision to select shouldn't be the subject of academic or scientific papers in the first place. There's far more context required in decision making than just how strong a correlation is.
Re:Statisticians want to abandon science’s standard measure ... by platz on Friday September 06, 2019 @11:40AM (#20896619)
I agree, but you might see how this error or preference creeps in psychologically
Re:Statisticians want to abandon science’s standard measure ... by usgroup on Friday September 06, 2019 @03:20PM (#20898936)
I’m a Bayesian flavoured, and the “problem” IMO is that model driven statistics are really hard and beyond most scientists (people generally tbh).

If we required scientists to be good statisticians there’d be far fewer scientists.

Re:Statisticians want to abandon science’s standard measure ... by godelski on Friday September 06, 2019 @04:14PM (#20899479)
Or we'd have just as many, but better at statistics.

P hacking isn't always done on purpose. It's misunderstanding. That's probably why it still passes peer review. There's also tons of incentives that encourage this behavior. These are the problems. An arbitrary mark to meet makes people weak at statistics not understand their data as well. I'd rather more accurate data than more scientists. More workers doing poor work isn't useful.

Also, you can Bayes hack. Bayes helps, but it doesn't address the underlying issues.

Re:Statisticians want to abandon science’s standard measure ... by buboard on Friday September 06, 2019 @09:48AM (#20895590)
Scientists have a duty to communicate what is true and what is not though. Passing that judgement duty to the general public is irresponsible and unwise (it's easy to claim anything with flawed / misleading statistics). Ideally someone would have come up with a framework that is better than statistic tests to justify levels of truth, but so far we dont have one
Re:Statisticians want to abandon science’s standard measure ... by mkl on Friday September 06, 2019 @09:53AM (#20895630)
When you've got empirically gathered data, pretty much every type of analysis you can do with it comes under the umbrella of "statistics". I think any better truth measuring framework can only be statistical.
Re:Statisticians want to abandon science’s standard measure ... by buboard on Friday September 06, 2019 @09:56AM (#20895656)
There are very few principles in science. Statistics tests seem to be something where scientists unanimouslu agree. Another is models, and applying occam's razor to choose the one with less parameters. Perhaps one could also justify choosing a hypothesis on the basis that it is simpler.
Re:Statisticians want to abandon science’s standard measure ... by bigfudge on Friday September 06, 2019 @10:24AM (#20895881)
They certainly don’t agree. There has been 30+ years of objection to p < .05. The fact that many scientists are statistically illiterate doesn’t constitute consensus.
Re:Statisticians want to abandon science’s standard measure ... by mkl on Friday September 06, 2019 @10:28AM (#20895916)
They pretty much agree that statistics is the tool to use, but disagree on the (important) details.
Re:Statisticians want to abandon science’s standard measure ... by buboard on Friday September 06, 2019 @12:52PM (#20897310)
Scientists (should) never really "agree", they just concede temporarily preparing their next attack. statistic tests are the de facto standard that everyone concedes to, and has not been replaced.
Re:Statisticians want to abandon science’s standard measure ... by merpnderp on Friday September 06, 2019 @10:40AM (#20896036)
Richard Feynman said anything you can't prove yourself must be taken on pure faith and most of the public must take everything on pure faith as somehow they've left school without the faintest idea how basic stats work.
Re:Statisticians want to abandon science’s standard measure ... by buboard on Friday September 06, 2019 @12:47PM (#20897256)
Feynman was talking to scientists. I do think that science has to provide answers, not just data. The public interprets every datum in a myriad of ways, and does not have a mechanism to establish consensus, hence you would end up with constant crisis.
Re:Statisticians want to abandon science’s standard measure ... by marknutter on Friday September 06, 2019 @01:57PM (#20897997)
Who says we're not in a constant crisis?