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Re:Periodic fasting starves cisplatin‐resistant cancers to d... by bad_user on Friday August 03, 2018 @09:36AM (#17679685)
Fasting is great for weight loss and for lowering your insulin resistance, which is now considered by many the main cause of obesity and of course type 2 diabetes. This has been shown by studies.

Some say that fasting activates "autophagy" which has great health benefits, supposedly being great for preventing the remission of cancer: https://en.wikipedia.org/wiki/Autophagy — but note that I could not find any concrete study or proof of it, this being anecdotal evidence from some clinics that advise their patients to do fasting instead of chemotherapy.

I practice fasting for 36 hours, 3 times per week. Monday, Wednesday and Friday I don't eat or drink anything other than water and coffee. You can go shorter, like one meal per day in some days or longer, e.g. 5 days is easy once you get used to it.

As a tip: eating high fat, low carbs meals before fasting helps. Also if you get dizzy or if you get cramps, you probably have an electrolytes imbalance and you need to stop your fast. If that happens to you, make sure to take salt (sodium) and possibly magnesium supplements. Once I started doing that, the dizziness and the cramps stopped. But document yourself first and consulting a doctor and doing some blood work might be good ideas.

This is a pretty good book on the subject: https://www.amazon.com/Complete-Guide-Fasting-Intermittent-A...

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by S_A_P on Friday August 03, 2018 @10:48AM (#17680292)
Ive recently started doing "mini" fasts combined with a keto diet to shed a few pounds. I usually just eat one meal per day at dinner time. While getting started on it was somewhat difficult after about 7 days I was in the groove and feel like this is a diet/lifestyle that I can maintain indefinitely. My hunger has changed from "IM STARVING FEED ME NOW" when I was eating 3 meals a day on no particular diet, to "hmm I guess I could eat". Energy wise, I do feel a lot better, and Ive shed 25 of the 50 lbs I need to get off of me. I was never much of a sweet eater, so I think Im lucky, as my wife who does have a sweet tooth has struggled eating Keto.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by cageface on Friday August 03, 2018 @09:53AM (#17679832)
There are lots of different carbs with many different metabolic profiles. And there are plenty of people out there living very healthy lives and even reversing heart disease and diabetes on high carb diets provided they are unprocessed whole carbs. Okinawans used to get the vast majority of their calories from sweet potatoes, for example, and were the longest living people in the world.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by bad_user on Friday August 03, 2018 @10:00AM (#17679877)
I am not contradicting you, however:

1. the diet of Okinawans is irrelevant because they are not eating the refined carbohydrates that we do and

2. that fasting is easier if you eat high fat, low carbs meals just before is a fact known for thousands of years, because fasting isn't new ... all major religions that practice water fasting allow meat just before a water fast

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by PerfectElement on Friday August 03, 2018 @12:00PM (#17680925)
- the diet of Okinawans is irrelevant because they are not eating the refined carbohydrates that we do

I think you missed the point the parent was making. No one is forcing you to eat refined carbohydrates. People conflate carbohydrates with "refined carbohydrates" and end up thinking that eating a bowl of brow rice, lentils and veggies will make you diabetic because "carbs".

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by geomark on Friday August 03, 2018 @10:58PM (#17685131)
Depends a lot on the type of rice. A couple of rice varieties have a higher glycemic index than pure glucose. A lot of people where I live are diabetic and don't understand why because they don't eat sweets. But they do eat large amounts of jasimine rice and Thai sticky rice; both have GI > 100.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by GordonS on Saturday August 04, 2018 @12:16PM (#17687396)
Even how much you cook the rice affects it's glycemic index - al dente rice has a lower GI than soft rice (same deal with pasta)
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by 738472527784 on Monday August 06, 2018 @03:59PM (#17701197)
OP said brown rice...
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by triviatise on Friday August 03, 2018 @04:07PM (#17683190)
they dont keep you full like protein does. Eating high protein moderate fat, low (not zero) carb reduces hunger to nothing for fasting.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by cageface on Saturday August 04, 2018 @01:32AM (#17685520)
Many carbohydrates have a higher satiety index than beef does, for example. Potatoes and oats are both more filling than a steak.

https://www.healthline.com/nutrition/15-incredibly-filling-f...

Legumes are high in carbohydrates and protein and are extremely nutritious and filling.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by GordonS on Saturday August 04, 2018 @12:20PM (#17687414)
Sorry, but I very much doubt this - potatoes have a very high glycemic index (sometimes higher than that of straight glucose!), so you will have a blood glucose crash shortly after eating them, causing you to feel hungry.

I have reactive hypoglycemia, and potatoes are something I strongly avoid for this reason (they will cause me to hypo as soon as 30 mins after eating them).

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by cageface on Sunday August 05, 2018 @11:34AM (#17691817)
Glycemic index and insulin response are two different things. Both can be measured directly in the blood and aren't a matter of opinion or anecdote.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by GordonS on Tuesday August 07, 2018 @10:17AM (#17706802)
I was responding to your post about satiety, not insulin response?

Eating potatoes causes your blood sugar to rise rapidly. When it falls, it invokes a feeling of hunger. Blood glucose can be measured directly in the blood, and isn't a matter of opinion or anecdote :P

I was suspicious of the results, so I just downloaded the paper that your link refers to - low and behold, it has this at the end:

"This study was supported by a competitive investigator-initiated grant from the US Potato Board"

Well, what a surprise!

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by com2kid on Friday August 03, 2018 @12:13PM (#17681045)
The Okinawan diet is also famous for being a calorie restricted diet. There is a famous saying there that roughly translates to "eat until you are 80% full".

Source: https://en.wikipedia.org/wiki/Hara_hachi_bun_me

I'm actually surprised that Wikipedia says they consume 1800 calories a day. When I am doing intermittent fasting I am around 1400-1600.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by r_c_a_d on Friday August 03, 2018 @09:59AM (#17679871)
I'm confused. Do you mean you fast for 12 hours on each of Monday, Wednesday and Friday, totalling 36 hours? Or you fast for 36 hours starting on Monday, Wednesday and Friday... which would be all of Monday and half of Tuesday etc?
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by bad_user on Friday August 03, 2018 @10:06AM (#17679930)
No, I mean I don't eat anything on Monday, Wednesday and Friday. If you count the hours, that's 36 hours windows, as it includes sleep.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by andreygrehov on Friday August 03, 2018 @10:35AM (#17680171)
Isn't it the same as what he said in "Do you mean you fast for 12 hours on each of Monday, Wednesday and Friday, totalling 36 hours"?
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by moate on Friday August 03, 2018 @10:43AM (#17680249)
No. It's 36 hours straight of not eating. Think of it like this: You eat dinner at 7 PM, and you go to bed at 11 PM Sunday and wake up at 7 AM. that's 12 hours of not eating. You don't eat anything at all on Monday, and again go to be at 11 PM. You've now fasted 29 hours. You sleep until 7 AM, for a total of 36 hours. You then immediately eat breakfast.

If you sleep for 8 hours and don't snack before bed, you would probably "fast" for 12 hours in a day incidentally

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by athenot on Friday August 03, 2018 @02:59PM (#17682626)
> If you sleep for 8 hours and don't snack before bed, you would probably "fast" for 12 hours in a day incidentally

Which is why that next meal is called "break fast".

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by pbhjpbhj on Friday August 03, 2018 @02:05PM (#17682054)
Snacking before bed is my problem. I miss breakfast, and sometimes lunch; but I sleep better if I'm digesting ... and I sleep badly.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by arcticbull on Friday August 03, 2018 @10:39AM (#17680219)
Sounds like they're fasting 36hx3 = 108h, not 12x3 = 36h.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by infogulch on Friday August 03, 2018 @12:12PM (#17681029)
OP said:

> 36 hours, 3 times per week

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by magneticnorth on Friday August 03, 2018 @10:40AM (#17680229)
I believe they mean that they don't eat from, say, 8pm on Sunday night until 8am Tuesday morning (and again covering Wednesday and Friday).
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by guru4consulting on Friday August 03, 2018 @12:00PM (#17680927)
He means eating on Saturday,Sunday,Tuesday,Thursday but fasting the whole day on Monday,Wednesday,Friday...
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by slackwalker on Friday August 03, 2018 @01:23PM (#17681679)
I see, so as an example, you eat your final meal at 6:00 Sunday night. Nothing Monday. Breakfast at 6:00 on Tuesday. 6:00p Sunday to 6:00a Tuesday is 36 hours.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by mygo on Friday August 03, 2018 @10:46AM (#17680279)
sounds interesting, but I’m the type of person who defaults to scrawny, and if I don’t eat anything 3 days out of the week I’d likely be underweight and look like a stick. And I wouldn’t be able to keep my weight lifting routine.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by mistaken on Friday August 03, 2018 @10:23AM (#17680085)
You have to be careful though; it's easy to get gallstones if you regularly fast and don't flush you're gallbladder with fatty foods afterwards.
[dead]
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by lolc on Friday August 03, 2018 @11:47AM (#17680799)
It's possible to know the difference and still make the mistake.

It's possible to write a candid comment and come across as an ass.

It's possible that I'm unable to shut my mouth against better judgement.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by istjohn on Friday August 03, 2018 @12:58PM (#17681464)
english -> English

spanish -> Spanish

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by aviv on Friday August 03, 2018 @10:53AM (#17680341)
Your username is highly accurate based on this statement. This is just complete non-sense.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by user9182031 on Friday August 03, 2018 @09:43AM (#17679744)
It seems like every day somebody has figured out how to beat type 2 diabetes. I just read Proteinaholic by Dr. Garth Davis who advocates a vegan lifestyle (while telling you that carbs are not the enemy) to cure diabetes.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by teekert on Friday August 03, 2018 @09:45AM (#17679770)
Carbohydrates come in many forms, simple ones like sugar make your blood sugar spike and this is widely considered bad (and what leads to diabetes type 2). Complex ones take very long to digest, some can even only be digested by your microbiome, deep in your gut, those carbohydrates make for a consistent, stable, small flow of sugar to the blood. Which is considered a good thing.

Try eating oats (no sugar, just yogurt and fruit for sweetening, don't get tricked into thinking honey or brown sugar is healthy sugar ;) I personally like strawberry or pomegranate but the latter is pretty expensive even in-season). Or try heavy whole wheat bread (with something like peanut-only peanut butter) and see how much longer it takes before you get hungry again, compare it to breakfast cereals or white bread. I really notice the difference. If you like sweet, try backing a cake from oats and banana (and some flour, pancakes of oat and banana are also very nice by the way), perhaps add some nuts as well. Works great for me (results of delayed hunger in the day are immediate, which is motivating). Oats are cheap, bananas generally as well.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by fencepost on Saturday August 04, 2018 @03:51PM (#17688199)
It's worth being aware that milk and milk products can actually have a pretty significant amount of sugar in the form of lactose.

"If you're lactose intolerant and looking for yogurt, go Greek. Greek yogurt, which is thicker because much of the whey, the watery part of milk, has been strained out in processing. This also removes much of the lactose. Greek yogurt supplies less than 6.8 grams of lactose per 6-ounce serving, compared to less than 8.5 grams in whole-fat yogurt or 14 grams in non-fat yogurt. Hard cheeses such as cheddar have even less lactose, between 0 to 2 grams per ounce. Milk, in comparison, has approximately 11 grams in one cup." (from https://healthyeating.sfgate.com/can-lactose-intolerant-eat-...)

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by bad_user on Friday August 03, 2018 @09:50AM (#17679809)
Our metabolism is very complex. But if it's not backed up by studies and science, it doesn't count.

Type 2 diabetes is defined by insulin resistance. The only way to "beat" type 2 diabetes is to lower your insulin resistance and thus to lower your insulin response. At the moment you can only lower your insulin with lifestyle changes that implies fasting + eating a diet that triggers a low insulin response.

The vegan lifestyle is high in carbs. What many people don't understand is that there are only 3 macro-nutrients: proteins, fats and carbs. You cannot do a low carbs diet without at least eggs and diary. And carbs stimulate insulin.

Note that there are clinics that have successfully treated people of diabetes via fasting. Here's one: https://idmprogram.com/

N.B. carbohydrates are not the enemy, but _refined carbohydrates_ are and unfortunately for a type 2 diabetic it's too late to switch to healthy carbs.

Yes, a potato is healthy, however for a diabetic it is basically poison.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by teekert on Friday August 03, 2018 @10:29AM (#17680116)
Complex carbs (fibers or at least carbohydrates that are slowly digested) do not stimulate insulin production as far as I know. I think it is very important to realize that there are different types of carbohydrates. You need fuel (carbs/sugars), you just don't need them to get rushed into your blood at breakneck speeds requiring massive insulin dosages to bring it back down. You want them supplied slowly and steadily to your blood during the day and night. Which is what happens when your body and your gut microbes slowly degrade complex carbs into smaller constituents, such as sugars.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by com2kid on Friday August 03, 2018 @12:16PM (#17681077)
There are people doing vegan keto. It is theoretically possible.

I imagine it is the most boring diet in the world though. :)

From what I've heard vegetarian Keto isn't too bad.

I'd worry about getting healthy oils on a vegan keto diet, healthy vegetable oils get expensive very fast. Most keto diets don't pay much attention to fat sources, but while lots of canola oil technically meets the macros, it'd not be healthy at all...

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by moate on Friday August 03, 2018 @10:54AM (#17680349)
Point of order: Many nutritionists would disagree with your definition of a macronutrient. If you're talking about bio-energy sources, you're leaving out Alcohol, which is metabolized differently than Carbs. If you're talking "things your body needs in great volume" water, fiber and antioxidants should be on the list.

Sorry, this is just a pet-peeve about how the Fitness/bodybuilding community talk about "macros".

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by camelNotation on Friday August 03, 2018 @09:46AM (#17679774)
There are a lot of ways to look at that, but I think what all these "cures" have in common is that they drastically reduce the amount of sugar in your diet and allow the body to essentially rest and reset its insulin response. I don't think it really matters how you do it as long as you do that.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by cageface on Friday August 03, 2018 @09:51AM (#17679816)
Note that protein also provokes an insulin response. This is why a steak will actually result in more insulin release than a plate of spaghetti.

https://en.wikipedia.org/wiki/Insulin_index

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by bad_user on Friday August 03, 2018 @10:02AM (#17679899)
> This is why a steak will actually result in more insulin release than a plate of spaghetti.

That's bullshit, but yes, proteins do provoke an insulin response, which can be unhealthy with enough proteins. Note however that proteins != fat and fat does not provoke an insulin response.

And yes, for diabetics fat meat is healthier than lean meat.

Also note that fat and proteins keep you satisfied for longer, so you end up eating less meals per day. This is not about calories, but about the insulin response.

If you keep eating, the insulin does not go down.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by jackhack on Friday August 03, 2018 @11:09AM (#17680494)
Can we please keep YC a civil place without the entirely unnecessary profanity which is pervasive everywhere else?

It's fine to disagree; but do so based on the strength of your argument and facts.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by cageface on Friday August 03, 2018 @12:53PM (#17681437)
This is a direct measurement of blood insulin levels. It's not somebody's opinion. Complex carbs are extremely satiating and plenty of people have reversed type 2 diabetes eating high carb diets.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by com2kid on Friday August 03, 2018 @12:36PM (#17681291)
I seriously question that satiety index.

I can, quite literally, eat 2000+ calories of potatoes and not be full. I make a damned good loaded baked potato, and good mashed potatoes for that matter. Are they talking about a plain boiled potato with nothing on it or something? (even then, boiled red potatoes are good... :) )

Or oranges for that matter. Give me a 2lb bag of satsuma oranges and I'll give you back an empty bag a short time later.

Listing beef as lower than oranges is incredibly weird to me. Apparently the average satsuma is 4oz, realistically compare two of those tiny mandarin oranges to an 8oz steak, the steak will satiate more and for a longer period of time. No study is needed to prove that.

Unless they were comparing by "equivalent calorie consumption" in which case the chart is useless, but sure, 1 mandarin orange is probably better than 1oz of steak. (~64 calories in 1 mandarin orange, ~77 calories in 1oz of steak).

Trying to make an actual meal out of the oranges would be, naturally, quite pointless, where as the steak scales up to a meal quite well.

And this is why a huge % of nutritional studies are useless for day to day living.

Naturally YMMV and I know people who are satiated off of small portion of high carb foods, but people who can eat a small bowl of ice cream and be full are the minority, with my evidence of that assertion being America's waistline (and the average serving size of ice cream).

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by cageface on Friday August 03, 2018 @12:51PM (#17681415)
2000 calories of potatoes is like 15 potatoes. You can really eat that many potatoes in a day?
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by com2kid on Friday August 03, 2018 @01:13PM (#17681591)
Not without toppings.

But I can make one hell of a loaded baked potato.

Or cheesy mashed potatoes.

Pretty much no one eats just a regular potato.

Which is where the table falls apart. You can cook up a steak with some salt and pepper, or a good steak with nothing at all on it, and eat it just like that.

A regular boiled potato? Meh.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by cageface on Friday August 03, 2018 @03:35PM (#17682921)
Satiety index is just a measure of how full you are after eating something. It’s not meant to factor in how much you enjoy eating it, which is of course a very subjective thing.

Myself I’d rather eat 15 potatoes than a steak any day. I like them with a lot of herbs and spices which add a lot of other nutrients.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by Zimahl on Friday August 03, 2018 @10:55AM (#17680369)
> This is why a steak will actually result in more insulin release than a plate of spaghetti.

As the husband of a type-1 diabetic I can assure you this is absolutely wrong. Fats and proteins are practically insignificant to carbohydrates, essentially they are inconsequential when calculating insulin injections.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by InitialLastName on Friday August 03, 2018 @05:28PM (#17683779)
Note that your husband doesn't actually release any insulin. So it's not about calculating appropriate insulin injections, it's about how insulin a normally-functioning body releases in response to eating food.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by cageface on Friday August 03, 2018 @12:53PM (#17681424)
This is a scientifically measured insulin response. It's not somebody's opinion. Note that this is different from blood sugar levels. You'll find the same numbers on every insulin chart.
Re:Periodic fasting starves cisplatin‐resistant cancers to d... by GordonS on Saturday August 04, 2018 @01:42PM (#17687746)
Sorry, but this is just demonstrably untrue.

I regularly check my blood sugar levels and protein doesn't affect them at all, whereas eating a bowl of spaghetti will raise it a lot.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by godshatter on Friday August 03, 2018 @11:13AM (#17680538)
I'm fine living in a world where there are many ways to "beat" type 2 diabetes. Intermittent fasting (I eat one meal a day) has dropped my A1C from 8.9 to 5.5 (probably less, now). I've been doing this for about 15 months so far. My type 2 diabetes is not cured, if I drop off the diet and go back to my old habits my A1C will undoubtedly go right back up. But it's an easy diet to live with, especially since I don't limit myself and can eat whatever I want, though given the choice I'll try to reduce the worst refined carbs.

The high carb / low fat diet isn't one of the ways to beat type 2, though, and it's still the one pushed by many dieticians.

Re:Periodic fasting starves cisplatin‐resistant cancers to d... by supernovae on Friday August 03, 2018 @10:49AM (#17680298)
I went vegan for 5 years, my cholesterol kept getting worse in every way.

Now i do keto, and my cholesterol is happy. Diabetes wasn't my direct concern but i find it interesting how eating a ton of eggs every day has improved my balance.