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Re:Liquid water 'lake' revealed on Mars by ChuckMcM on Wednesday July 25, 2018 @11:31AM (#17610035)
This is a false dichotomy that always annoys me. It is entirely possible that by spending $400B to safely send people to Mars and live there, especially in a moderately high radiation environment, that we will discover EXACTLY the mechanisms that send cells into cancer states and how to reverse that so they stop. Otherwise we're going to have colonists getting cancer and dying too quickly.

Then not only do we get to be multiplanetary so that when the crap really starts hitting the fan there is a lifeboat, but we also cure cancer.

Re:Liquid water 'lake' revealed on Mars by wilsonnb2 on Wednesday July 25, 2018 @11:35AM (#17610058)
It's also entirely possible that the cure for all forms of cancer is a diet consisting entirely of frosted flakes, and that spending $400B researching the effects of all-cereal diets would also discover the cure for cancer.

However, it's far more likely that $400B in cancer research will do more for curing cancer than hoping for side effects from $400B in other research.

Re:Liquid water 'lake' revealed on Mars by ChuckMcM on Wednesday July 25, 2018 @12:03PM (#17610272)
We have already spent $500B on cancer research[1] and it hasn't cured. This also isn't an "either/or" proposition. As I mentioned, people travelling in space are subject to a lot of radiation which is known to cause cancer, so part of the research is going to be figuring out how to fix cells that are cancerous.

Cancer is a systemic problem, it isn't measles or polio or TB. You have to understand the system in order to fix it and pushing humans into new environments will give us better insights into the system we call human life.

[1] https://bigthink.com/devil-in-the-data/the-never-ending-war-...

Re:Liquid water 'lake' revealed on Mars by forapurpose on Wednesday July 25, 2018 @12:33PM (#17610535)
> We have already spent $500B on cancer research[1] and it hasn't cured

That's a pretty absolutist statement. We've spent more preventing murder, but murder still happens. We have developed many treatments for cancer that have added many quality life years for millions of people.

Re:Liquid water 'lake' revealed on Mars by ChuckMcM on Wednesday July 25, 2018 @04:03PM (#17612316)
I agree, both that it is absolutist and that we've spent more on preventing murder. What is the common thread to both of these absolutist comments? Both cancer and murder are systems in crisis, not 'things' in their own right. They have the same questions

1a) What causes a cell to decide live forever (metastasize)?

1b) What causes a person to decide that killing another person is the solution to some problem?

2a) How can we detect a cell that is about to metastasize? How can we stop it?

2b) How can we detect a person that is about to murder? How can we stop them?

3a) What would have to be true for cancer to never be the cause of death ever again?

3b) What would have to be true for murder to never be the cause of death ever again?

See? Both are systems where individual elements within the system have decided to work against the system rather than within its constructs.

There is no drug, no treatment, that will 'cure' cancer until we understand exactly what is going on in a cell that knocks it out of line. And there will be no end to murder until we understand exactly what is going on inside a person's head when they decide that is the correct course of action. Everything we do on these two fronts (cancer, and murder) are delaying actions to minimize their impact on the greater whole.

The other part that some people have assumed (but the GP did not) is that spending this money on Mars exploration would reduce the amount of money that is currently allocated to cancer research. It wouldn't, it was specified as 'new funds'.

Re:Liquid water 'lake' revealed on Mars by forapurpose on Wednesday July 25, 2018 @09:37PM (#17614469)
> There is no drug, no treatment, that will 'cure' cancer until we understand exactly what is going on in a cell that knocks it out of line. ... Everything we do on these two fronts (cancer, and murder) are delaying actions to minimize their impact on the greater whole.

So what? Even if everything you say is true, the outcome of the research is possibly hundreds of millions of additional quality life years.

And there are many treatments that 'cure' cancer. Many people have cancer, are treated, and never have it again. Many have it, are treated, and live much longer than they otherwise would have. I'm not sure what you are saying, or why research that saves and prolongs lives has to meet some other standard (and what is that standard?).

Re:Liquid water 'lake' revealed on Mars by anticensor on Wednesday July 25, 2018 @05:45PM (#17613185)
Yes, cancer and murder are duals. Do you think there may be a way to convert between measures against either?
Re:Liquid water 'lake' revealed on Mars by ChuckMcM on Wednesday July 25, 2018 @06:03PM (#17613331)
Not sure how this relates to the argument. Can you be a bit more specific?
Re:Liquid water 'lake' revealed on Mars by bordercases on Wednesday July 25, 2018 @01:07PM (#17610880)
I think what might be more damning is if the preventative measure for cancer is better full spectrum healthy habits
Re:Liquid water 'lake' revealed on Mars by mattigames on Wednesday July 25, 2018 @11:53AM (#17610186)
Imagine giving someone 200 years ago $400B for cancer research; what do you think it would have happen? Do you think they would have found the cure? No. The same thing happens today, $400B may do nothing big for cancer research and what's needed to advance in that area its time; decades (maybe centuries) of advancements in many fields that are not directly related to cancer research but given enough time those advancements will be used together to find a cure (e.g. map the entire DNA; nanorobots, etc)
Re:Liquid water 'lake' revealed on Mars by enraged_camel on Wednesday July 25, 2018 @12:32PM (#17610529)
There are about a thousand things you use and benefit from everyday that were side effects of other research and spending (primarily military). But you take them for granted and so it is easy for you to make value judgments regarding how money is spent.
Re:Liquid water 'lake' revealed on Mars by SiempreViernes on Wednesday July 25, 2018 @01:06PM (#17610862)
Eh, the military invents very few things, they mostly spend money on custom development of existing tech to make it better at killing things or facilitating the killing of things.

The car, the calculating machine, the photograph, the steam engine, the radar: none where invented by military men or even those funded by the military.

Re:Liquid water 'lake' revealed on Mars by gls2ro on Wednesday July 25, 2018 @02:32PM (#17611617)
I might be very wrong (as I don’t have right now time to research more) but I think _the calculating machine_ and _the radar_ are things actually created as usable products because the military needed them in the first place. I am not in favor of spending (more) money on military.
Re:Liquid water 'lake' revealed on Mars by SiempreViernes on Wednesday July 25, 2018 @06:04PM (#17613333)
Not really, their further development certainly benefitted from military money, but the basics came from civilian need for navigation, in general and in mist.
Re:Liquid water 'lake' revealed on Mars by mattkrause on Thursday July 26, 2018 @02:48AM (#17615522)
I'm fairly certain this is not true. Marconi and Hülsmeyer had some early ideas about using radar to find ships, but they weren't really developed and didn't use the pulsed approach that subsequent systems used.

This wikipedia article (https://en.wikipedia.org/wiki/History_of_radar) suggests a huge military involvement from the 1930s onwards

Re:Liquid water 'lake' revealed on Mars by SiempreViernes on Thursday July 26, 2018 @04:32AM (#17615948)
If you count nothing but the earliest version of military radars, then of course nothing but the military has funded it.

I will, however, not count pulsing as more than an improvement to the basic invention of distant object detection with radio waves.

As you can read on the page you linked Hülsmeyer made a working system, clunky as it was, for detecting ships in mist. Taking a system from prototype to mass produced, worthy as this investment might be, is not inventing it.

Re:Liquid water 'lake' revealed on Mars by wilsonnb2 on Wednesday July 25, 2018 @12:41PM (#17610609)
> But you take them for granted and so it is easy for you to make value judgments regarding how money is spent.

It's rude to make such assumptions about me. I do not take the positive side effects from research for granted.

You simply haven't made a case showing why $400B in space research will generate more or better positive side effects than $400B in cancer research.

All research will have side effects that can't be anticipated. It's stupid to perform research with "random, unknowable" side positive side effects as a primary justification.

Re:Liquid water 'lake' revealed on Mars by enraged_camel on Wednesday July 25, 2018 @01:02PM (#17610824)
>>You simply haven't made a case showing why $400B in space research will generate more or better positive side effects than $400B in cancer research.

You made the original claim that spending that money on cancer research would be more beneficial. The burden of proof is on you, not me.

Re:Liquid water 'lake' revealed on Mars by pc86 on Wednesday July 25, 2018 @01:33PM (#17611104)
Eventually the Earth is going to be hit by an asteroid or cooked by the sun. It's an eventuality that on cosmic timescales is going to happen sooner rather than later.

Getting mankind off of Earth and spread across multiple planets and solar system will yield untold positive side effects, and one or more of those may impact cancer research.

More cancer research is not going to stop an asteroid.

Re:Liquid water 'lake' revealed on Mars by xvector on Wednesday July 25, 2018 @04:12PM (#17612369)
> Getting mankind off of Earth and spread across multiple planets and solar system will yield untold positive side effects, and one or more of those may impact cancer research.

And yet perhaps one of the blocks with modern science is people hitting the grave before they can finish innovative research. It takes at least 26 years to train a human from scratch to advance to basic research level in a field. You can add another 10, 20 years before proficiency. At least half the human life until total proficiency (as it stands) is reached and perhaps a quarter of the human life for which researchers can make meaningful contributions.

Arguably, focusing on problems on Earth - like eliminating mortality, solving longevity, curing cancer and dealing with death - will do more for our species long-term than exploring space right now. When your scientists live longer, more discoveries, contributions, and innovations can be made.

Spending $400B on dealing with the greatest tragedies and sources of sorrow known to mankind today - death, disease, illness - would be far preferable to most people than investing in space.

Re:Liquid water 'lake' revealed on Mars by pixelbash on Wednesday July 25, 2018 @03:18PM (#17611990)
So far our legacy as a species on earth is one of destruction. Only by taking on the challenge a place that is already dead can we be certain of creating something new. Maybe we will learn some perspective in the process.

Going to Mars will have myriad discoveries & side effects, if we knew what they were what would be the point of going?

Also, what if curing cancer is harder than going to mars? One is by now a fairly quantifiable objective, the other is debugging a mind bogglingly complex system with no version control.

Re:Liquid water 'lake' revealed on Mars by ptero on Wednesday July 25, 2018 @01:49PM (#17611244)
I think it is the other way around. Somewhere up the thread someone made the that instead of spending 400B on space travel we should have spent it on cancer research.

There was little, if any, explanation of why this should be done; and the posters arguing the opposite are, in my view, suggesting some of the "why not" arguments. The burden of proof is still on the fellow who made that "we should" claim. My 2c.

Re:Liquid water 'lake' revealed on Mars by gamblor956 on Wednesday July 25, 2018 @12:22PM (#17610444)
Cancer isn't one disease, it's dozens, each with different causes.

For example, almost all cases of cervical cancer are traced to HPV infections...so the research into the HPV vaccine arguably did more to reduce future cancer cases than research into cancer has. Further research showed that HPV can also cause a number of cancers in men (though at lower rates), which is part of the justification for offering the HPV vaccine to boys.

Re:Liquid water 'lake' revealed on Mars by robotrout on Wednesday July 25, 2018 @12:50PM (#17610699)
Cancer is often caused when tissue is damaged and needs to heal or try to heal itself repeatedly (inflammation).

Sunburn, smoking, chewing tobacco, HPV, acid reflux, can all cause cancer. Saying those are all different cancers that require different cures is a good way to waste a lot of effort and money. It is more accurate to say that inflammation is a cause for cancer, and focus on that.

Re:Liquid water 'lake' revealed on Mars by TeMPOraL on Wednesday July 25, 2018 @12:57PM (#17610776)
Point is, this is one of but many causes of diseases jointly classified as "cancer". Cancers share similarities in their (visible) method of action, but they have very different causes. There isn't going to be a single cure for "cancer".
Re:Liquid water 'lake' revealed on Mars by robotrout on Wednesday July 25, 2018 @01:04PM (#17610850)
Yes, there are many causes. We are in violent agreement. If you focus on the causes, you are preventing cancer, not curing it. You are playing whack-a-mole.
Re:Liquid water 'lake' revealed on Mars by bordercases on Wednesday July 25, 2018 @01:09PM (#17610897)
LOL Seems more cost efficient long run to address lifestyle than deal with proximal consequence
Re:Liquid water 'lake' revealed on Mars by fucking_tragedy on Wednesday July 25, 2018 @01:52PM (#17611259)
The thing about cancer is that you can live a perfect lifestyle and still have it ravage your body.
Re:Liquid water 'lake' revealed on Mars by newnewpdro on Wednesday July 25, 2018 @02:02PM (#17611346)
The reality is there's no escaping the causes for cancer, many of which are environmental and increasing. No amount of lifestyle change is going to eliminate the growing number of carcinogens present throughout our air, food, and water.
Re:Liquid water 'lake' revealed on Mars by robotrout on Wednesday July 25, 2018 @01:22PM (#17611017)
OK. You tell your mom that, after she's gotten cancer, asshole. How did her lifestyle cause her cancer in her ovaries (another inflammation caused cancer), I wonder?

While you're chastising your mom for her lifestyle, the rest of us will be looking/hoping for a cure.

You should know that even you will experience increased and chronic inflammation as you age, no matter how much better than your mom, your lifestyle is. Increased chronic inflammation and aging are linked and we're still trying to understand why.

Re:Liquid water 'lake' revealed on Mars by dang on Friday July 27, 2018 @03:37AM (#17624177)
> You tell your mom that, after she's gotten cancer, asshole.

Posting like this is a bannable offense. I'm not going to ban you for this because it's clearly a personal topic, but if you post like this again, we will. Please review https://news.ycombinator.com/newsguidelines.html and follow the rules from now on.

Re:Liquid water 'lake' revealed on Mars by bordercases on Wednesday July 25, 2018 @03:08PM (#17611930)
My mother did get breast cancer and it went into remission partially by increasing the quality of her lifestyle during and after treatment, as mandated by a pilot study she went through to help assess such an intervention. The lifestyle change was more extreme than what we would have considered necessary before her cancer, but doing cardiovascular exercise every day is already known as having an influence on bodily inflammation. Yes chemotherapy was involved but we are speaking of where the next span of marginal investment would have to go to make the highest impact.

At the individual level finding a cure would be great, and during late-stage we would definitely want to understand how to have more successful treatments, but to remove the long-term load of the cancer problem on the medical system would mean better environmental and lifestyle interventions which act at a level of root cause instead of proximal treatment. If anything maybe we would find common ground have having cheaper diagnostics so that we could find more motivation to engage in preventative measures concretely rather than as a catch all.

Re:Liquid water 'lake' revealed on Mars by robotrout on Wednesday July 25, 2018 @07:41PM (#17613925)
Nice that your mom got better with her breast cancer. I'm sure you know that a lot of breast cancer "survivors" are victims of an over hyped mammogram screening that calls any lump, no matter how slow growing, "cancer". Whether that's what your mom had or not, it's still scary though. [1]

My mom died of ovarian cancer after living a lifestyle that even you would approve of. Victim shaming pisses me off.

Shaming the victim with this lifestyle bullshit is not productive, and neither is minimizing people who actually search for cures rather than preaching lifestyle.

[1] https://www.bmj.com/content/348/bmj.g366

Re:Liquid water 'lake' revealed on Mars by monadgonad on Thursday July 26, 2018 @02:05AM (#17615362)
> Victim shaming pisses me off.

Yet you’re going right ahead and assuming that someone else’s experience is not _real_ cancer because they survived it and your mom didn’t? You really don’t have the right to be calling anyone else an asshole.

> and neither is minimizing people who actually search for cures rather than preaching lifestyle.

It seems like your feelings about your mom are preventing you from thinking objectively about this. Lifestyle can be a cure as well as a preventative, an extremely effective one, but that’s often overlooked because it’s easier and more profitable to get someone to take pills than it is for them to change all their dietary and exercise habits. Attitudes like yours, that say it’s wrong to call it anyone’s fault, really don’t help.

Re:Liquid water 'lake' revealed on Mars by stickfigure on Wednesday July 25, 2018 @04:45PM (#17612662)
You have that precisely backwards. The humans don't get sent to live in a high-radiation environment until we figure out hot to prevent the cancers. We're not just going to send a bunch of people to their death.

This is what irks me about "send people to Mars!" - we aren't anywhere near high enough on the technology tree to even contemplate the endeavor. Or to quote Bruce Sterling:

I'll believe in people settling Mars at about the same time I see people setting the Gobi Desert. The Gobi Desert is about a thousand times as hospitable as Mars and five hundred times cheaper and easier to reach. Nobody ever writes "Gobi Desert Opera" because, well, it's just kind of plonkingly obvious that there's no good reason to go there and live. It's ugly, it's inhospitable and there's no way to make it pay. Mars is just the same, really. We just romanticize it because it's so hard to reach.

Re:Liquid water 'lake' revealed on Mars by ChuckMcM on Wednesday July 25, 2018 @04:58PM (#17612743)
I like this image, although when I think about deserts I think about the Mojave desert and the people who died crossing it to get to the gold that was in the Sierra's. Or the oceans people crossed to get to the Americas. While there is 'hospitable' there is 'hard to survive' and I think surviving a journey across the ocean with 16th century tech might have some parallels.

I get the mindset of staying at home around the known campfire and the known wildlife and the known hazards. But I observe that it has never been a winning strategy for humans.

Re:Liquid water 'lake' revealed on Mars by stickfigure on Wednesday July 25, 2018 @06:03PM (#17613332)
There's a pretty substantial difference between "living on the other side of the ocean" and "living in a submarine", which is probably what life on Mars would be like given foreseeable technology. It's not just fear of the unknown. It's the sheer practical matter that life on Mars (if possible) will be extremely difficult, and the only obvious benefit is that you can say "hey look, I'm on Mars!"

Hell, you can simulate life on Mars by signing up for a career in deep sea diving. Actually, deep sea diving is probably a million times easier since you can pretty easily get parts from the surface.

I should have posted the full Bruce Sterling quote:

I'll believe in people settling Mars at about the same time I see people setting the Gobi Desert. The Gobi Desert is about a thousand times as hospitable as Mars and five hundred times cheaper and easier to reach. Nobody ever writes "Gobi Desert Opera" because, well, it's just kind of plonkingly obvious that there's no good reason to go there and live. It's ugly, it's inhospitable and there's no way to make it pay. Mars is just the same, really. We just romanticize it because it's so hard to reach.

On the other hand, there might really be some way to make living in the Gobi Desert pay. And if that were the case, and you really had communities making a nice cheerful go of daily life on arid, freezing, barren rock and sand, then a cultural transfer to Mars might make a certain sense.

If there were a society with enough technical power to terraform Mars, they would certainly do it. On the other hand. by the time they got around to messing with Mars, they would have been using all that power to transform _themselves_. So by the time they got there and started rebuilding the Martian atmosphere wholesale, they wouldn't look or act a whole lot like Hollywood extras.

Re:Liquid water 'lake' revealed on Mars by ChuckMcM on Wednesday July 25, 2018 @06:54PM (#17613675)
I don't disagree, just like there is a substantial difference between living in a submarine and living in orbit. But we've gone from "impossible to live in a submarine" to living in orbit in less than 100 years."

There are a lot of indications that 'living under conditions that were true for the last 1500 years but may not be available again for a while' is also a good plan. A city on Mars is likely a 100% energy sufficient and materials sufficient city. Such a city could survive any global warming catastrophe as well.

Most of this discussion comes down to various belief systems. I believe that any civilization that can live on Mars will also be able to treat cancer effectively, as well as survive other threats like asteroid bombardment, climate change, or major volcanic events. I don't believe that a civilization that can "only" treat cancer can survive those other problems. Clearly others have a different set of beliefs and that guides their research investment priorities.

Re:Liquid water 'lake' revealed on Mars by jpatokal on Wednesday July 25, 2018 @07:34PM (#17613879)
Um, we have settled the Gobi Desert and there's plenty of ways to make it pay, most notably this one:

https://en.wikipedia.org/wiki/Oyu_Tolgoi_mine

Re:Liquid water 'lake' revealed on Mars by stickfigure on Wednesday July 25, 2018 @09:38PM (#17614473)
This is a good illustration of what Charlie Stross says:

But even so, when you get down to it, there's not really any economically viable activity on the horizon for people to engage in that would require them to settle on a planet or asteroid and live there for the rest of their lives. In general, when we need to extract resources from a hostile environment we tend to build infrastructure to exploit them (such as oil platforms) but we don't exactly scurry to move our families there. Rather, crews go out to work a long shift, then return home to take their leave. After all, there's no _there_ there — just a howling wilderness of north Atlantic gales and frigid water that will kill you within five minutes of exposure. And that, I submit, is the closest metaphor we'll find for interplanetary colonization. Most of the heavy lifting more than a million kilometres from Earth will be done by robots, overseen by human supervisors who will be itching to get home and spend their hardship pay.

This is not "settling" the Gobi desert any more than manning an oil rig is settling the north atlantic.

Much more well-reasoned detail here:

http://www.antipope.org/charlie/blog-static/2007/06/the_high...

Re:Liquid water 'lake' revealed on Mars by Tloewald on Wednesday July 25, 2018 @01:43PM (#17611182)
I look forward to seeing the summary of this discussion thread on n-gate.

If Earth were hit by a dinosaur killing asteroid it would be more habitable than mars before, during, and after.

Any ridiculous boondoggle might have beneficial side effects. There’s no evidence, however, that spending money on a boondoggle is a more effective way of generating positive side effects than spending the same money on something sensible.

I contend that if we were to spend $400B on a crash program to cure cancer we might accidentally end up figuring out how to live safely on mars.

Re:Liquid water 'lake' revealed on Mars by mnl on Thursday July 26, 2018 @12:20PM (#17618635)
My thoughts exactly about n-gate.

There's this funny assumption that the Earth might get hit by an asteroid but such an event can't happen to Mars. I'd like to know why Mars is asteroid-safe. Also what's the rationale in going to what in fact is an extinct planet to deal with the possibility of extinction in this of ours, which despite the bad press has been sustaining life continuously for billions of years.

Re:Liquid water 'lake' revealed on Mars by vxNsr on Wednesday August 01, 2018 @01:18PM (#17664581)
personal callouts.

You've been seen!