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Re:Paint.Net 4.0 is now available by shurcooL on Wednesday June 25, 2014 @03:55AM (#7942728)
Pixelmator is my go-to OS X alternative.
Re:Paint.Net 4.0 is now available by mythz on Wednesday June 25, 2014 @06:51AM (#7943184)
Massive fan of Pixelmator, my #1 goto option on OSX. Very few apps have Pixelmator's quality and polish.

Paint.NET is a great option on Windows for quick and easy graphic work, has been enough to keep me off Photoshop (as a web dev) for years.

Re:Paint.Net 4.0 is now available by TarpitCarnivore on Wednesday June 25, 2014 @09:07AM (#7943625)
What got me to buy Pixelmator was the amount of instructional material they provide on their website, that is well laid out and easy to follow.
Re:Paint.Net 4.0 is now available by bakareika on Wednesday June 25, 2014 @04:11AM (#7942775)
I second Pixelmator. It's great for simple edits, and also provides some of the more complex, Photoshop-esque tools. Also pretty fast.
Re:Paint.Net 4.0 is now available by rimantas on Wednesday June 25, 2014 @04:30AM (#7942811)
+1 for Pixelmator, but there is also Acorn, quite popular.
Re:Paint.Net 4.0 is now available by shaunpud on Wednesday June 25, 2014 @06:02AM (#7943030)
Seashore isn't too bad either, http://seashore.sourceforge.net
Re:Paint.Net 4.0 is now available by Tyrannosaurs on Wednesday June 25, 2014 @06:09AM (#7943051)
Yep, I like (and own and use) Pixelmator but before I was willing to pay money for something, Seashore was my go to app for basic editing.

My understanding is that it's bits of the GIMP processing engine with a nicer UI.

Re:Paint.Net 4.0 is now available by rogerdpack on Wednesday June 25, 2014 @09:13AM (#7943650)
That would be a non-free alternative...