Negative points for that company name.

How can you be so sure about that?

surely it should be +/- points for the company name

In my version of the multiverse, it turned out to be -

I think the article correctly points out the problem with the story of the company. At least to investors, their effort looks too unfocused by trying to be everything at once. Is it a software company or biotech company? I guess you’ll have to open the box to find out.

From my observations, I think Cony is very quick to identify when a particular technology has outpaced the rest is the portfolio, and so he is very quick to spin up a new venture to try and capitalize on that, rather than waiting for the rest of the portfolio to catch up and deliver.

How many useful technologies were created in pursuit of a goal that ultimately was never realized, but were later repurposed into something incredible in an entirely different field or market? My guess is (and this is just a guess), that the newcos were attempts to capitalize on technology created in pursuit of other goals. If you need 5 things to come together to design a drug, and you only get 3 of them, you may fail to get the drug, but you still have 3 pieces of valuable technology that it might make sense to commercialize.

Also, biotech failure rate is up there with restaurants. It's always a roll of the dice....so if you can roll more dice for marginal cost, its basically always a good idea.

> Schrödinger (NASDAQ: $SDGR) uses quantum mechanics to design new medicines and materials. Schrödinger is also a key AI winner.

So like Theranos? But with all the latest marketing buzzwords.

The company is an established leader in molecular design software suite. Everyone uses their docking software.

TIL Docking: https://en.m.wikipedia.org/wiki/Docking_(molecular)

There is also another definition you may or may not find as interesting!

Not remotely, Schrödinger is well established and basically leads the commoditized computational chemistry market. In fact, there are very many companies that would love to find a cheaper alternative to Schrödinger tools, but no alternatives are performant enough.

Interesting, but doesn't really overlap with Glide docking at all.

Ligand-receptor docking is one of the many additional modules ModelMole does as part of the custom pipelines, along with things like pH constant, thermal stability and more. I know as I'm one of the directors, happy to talk more if you're interested.

Interesting. Couple questions:

Why only mention peptides?

Does it work on membrane proteins?

How do performance and cost compare to Glide? Or Vina? (Performance anyways)

My email is firstname.last names superluminalrx.com

Are you implying that quantum mechanics is not that important to medicine and material design?

“Think bigger” - what do you mean Jensen?

“I mean, buy more Nvidia GPUs” - Jensen.

My message to Huang after spending hours trying to get nvidia/cuda drivers installed: think better.

Ya know I used to have these types of issues more often but I was a.) on PopOS instead of arch (which i use now) and b.) it was awhile ago and the software seemed to have matured a bit.

As such, Im a little surprised to see someone blaming Nvidia specifically for issues rather than Windows, WSL, or any distribution of linux that makes it difficult to install software outside of the official channels (e.g. debian variants). Can you elaborate on the context?

Seems sensible to blame Nvidia for driver issues while everyone else provide upstream kernel and userspace drivers nowadays.

Linus expressed clearly what many feel on the matter.

POPos has a nvidia iso? I haven’t used it but did things go awry for you using that?

A few times. Hence the switching to Arch.

What trouble did you have?

If you're all wondering why that company name is a bad one, I would urge you not to look into the personal life that that particular scientist.

That sounds completely irrelevant to the company.

Well I did say DON'T look into it, but ya'll had go ahead and Streisand this.

You’ve got 88 in your name bro DON’T look into that

This was actually the year I was born. Also very auspicious if you're Chinese. I'd be the most asian white supremacist north of Tila Tequila if this was actually a coded Neo Nazi user handle.

(Also, don't look up Tila Tequila Nazi's you won't like what you find)

So you're saying your name shouldn't be associated with every possible negative thing that can be related to it?

Which part? The one where he had a kid with his colleagues wife? Or the one where he was "petting and cuddling" 14 year old girls he tutored?

Both parts are completely irrelevant to the company yeah.

Barbara Streisand effect.

Wow, did not know that about his history. What a scumbag.

While irrelevant, I have to thank you for bringing this to my attention - I had no idea that he was, by all accounts, a pedophile. How disappointing.

what I read basically is Jensen bullied Huang into buying more GPUs and embracing the AI crapware.

> basically is Jensen bullied Huang into buying more GPUs

Jensen is Huang. Jensen Huang is NVidia’s CEO.

Schrödinger’s CEO is Ramy Farid

yeah I messed that up, but your correction is right and is what I meant :)

I do think you have to have a split personality a la Dr. Jekyll and Mr. Hyde in order to be CEO of nvidia.

You can clearly see this struggle for control anytime poor Huang has to a present new GPU, the evil Jensen comes roaring out "the more you buy... More you save".

Trying to grab some marketing shine from dropping names of market juggernaut Nvidia and CEO