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Re:Bryan Johnson – The Most Expensive Eating Disorder by Mistletoe on Tuesday December 10, 2024 @09:32PM (#42384090)
I don’t think you understand how down the rabbit hole this guy goes.

> Bryan Johnson’s supplements list includes more than 100 compounds taken as powders, tablets, and capsules, designed to support different aspects of his health.

This is an insane thing to do and I have delved deeply into supplements myself and it is stunning how hard it is to find evidence that any of them do anything beneficial long term.

This matches me own experience and daily diary of trying things, rating how I feel, bloodwork, etc. The only thing I’ve ever found beneficial long term is testosterone, sunlight, and exercise.

Re:Bryan Johnson – The Most Expensive Eating Disorder by bitzun on Tuesday December 10, 2024 @09:39PM (#42384157)
He sells supplements, including specific ingredients for which there isn't much evidence of efficacy. Even if you assume most of what he preaches and sells is scientific, some of it is unscientific which sort of undermines the entire pitch, I think.
Re:Bryan Johnson – The Most Expensive Eating Disorder by BadHumans on Tuesday December 10, 2024 @09:40PM (#42384161)
Testosterone in the form of steroids and TRT? Not judging just curious.
Re:Bryan Johnson – The Most Expensive Eating Disorder by Mistletoe on Wednesday December 11, 2024 @02:45PM (#42391965)
Just trt, actually going too high >1000 feels awful to me.

Just fixing this world decline helps so much.

https://sci-hub.se/10.1016/j.euf.2020.02.006

Re:Bryan Johnson – The Most Expensive Eating Disorder by xenator on Tuesday December 10, 2024 @10:14PM (#42384348)
There is also big question isn't it is more harm to the system removing its ability to produce what it should produce by itself.
Re:Bryan Johnson – The Most Expensive Eating Disorder by wyldberry on Tuesday December 10, 2024 @10:04PM (#42384300)
Yeah, you won't find evidence for two decades because of the time and resourcing it would take to fund it, plus none of them being in metabolic wards.

You can sit around and wait for "The Science" or you can be a data point for yourself.