If you have access to the game's memory etc, it's pretty easy to create an aimbot or thing that lets you see thru walls et cetera.
How you gonna cheat in a moba? It's a strategy game, you need, like, cutting edge AI to beat the best humans at it. In fact OpenAI specifically worked on an AI to play Dota 2, it was that hard.
Mind you I don't know if that's the case on privately hosted servers as well, since those could be manipulated to give players the points needed to get the lootboxes.
Not that there isn't options of making money that do benefit from cheating. Like creating high ranking accounts to sell. Which some people buy for the status of the rank...
Escape from Tarkov comes to mind. An extremely hard and niche first person shooter with RPG elements. It is a private Russian company so we don't know exact player numbers, but it is estimated to be ~200k by some hits in a google search.
There are people who will provide carry services and guns and gear for plenty of people who will pay for it, as well as other providers selling the cheats that the carriers use for a weekly fee. The people who are providing these services are getting paid in USD when their local currency has a far lower value. It isn't a moral thing, it is a money thing.
You know that you sometimes don't know a bug exists before someone exploits it or uses your software in a way that you did not think of. There are experts who stand to make tons of cash if they can create or use an exploit that people will pay money to advance with.
The only way to prevent this is something that no one wants to hear, but it needs to be a unique citizenship identifier of some sort, since HWIDs and other means of tracking are mostly useless.
FPS games are kind of the gold standard when it comes to competitive environments, and thus gather cheaters or people complaining about cheaters substantially more than most other game genres.
Which seem to be exclusively FPS games with ~10+M players ?
I don't even remember the last time when I've heard of a game outside that very narrow (albeit decently popular) category to have complaints about cheaters. Meanwhile for these games, I hear about it like every month, and all this despite this genre being amongst the ones that I play the least !