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Re:Eye scans detect signs of Parkinson’s disease up to seven... by devindotcom on Tuesday August 22, 2023 @11:40PM (#37231585)
I recall two companies working on this - RightEye and Neuralight:

https://techcrunch.com/2018/02/17/righteyes-portable-eye-tra...

https://techcrunch.com/2022/05/24/neuralight-aims-to-track-a...

Probably there are more by now. As I recall this data is great for essentially saying "you should go get a real test." No one is diagnosing - just saying that a certain, say, eye movement slowness is correlated and you can detect it much earlier than a hand tremor or other more prominent symptoms.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by harry8 on Tuesday August 22, 2023 @11:47PM (#37231617)
is early diagnosis useful?
Re:Eye scans detect signs of Parkinson’s disease up to seven... by kadoban on Wednesday August 23, 2023 @12:00AM (#37231710)
If nothing else, it could allow you to make different decisions in your life. If my mind is going to be gone in 10 years, I'm sure as shit not saving for long term retirement anymore.
Re:Eye scans detect signs of Parkinson’s disease up to seven... by tasty_freeze on Wednesday August 23, 2023 @12:15AM (#37231812)
> If my mind is going to be gone in 10 years

Parkinsons affects motor control, not mental functioning. The point still stands -- if I got a diagnosis I would be less likely to embark on learning to play the piano, and I'd start educating myself on the disease.

EDIT: I'll correct myself. It primarily affects motor control, but late in the disease it can affect cognition.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by wombatpm on Wednesday August 23, 2023 @12:39AM (#37231941)
Lewey Body Dementia is common with Parkinson’s
Re:Eye scans detect signs of Parkinson’s disease up to seven... by JimtheCoder on Wednesday August 23, 2023 @12:30AM (#37231894)
"if I got a diagnosis I would be less likely to embark on learning to play the piano"

Perhaps counterintuitively, doing something like learning to play the piano could potentially slow the progression of fine motor skill impairment. Same with things like Tai Chi, dancing, exercise in general...

Re:Eye scans detect signs of Parkinson’s disease up to seven... by hacoo on Wednesday August 23, 2023 @02:45AM (#37232578)
Every case is different , but Parkinson’s is often associated with severe dementia that can manifest fairly quickly. I saw this happen to a close family member unfortunately.
Re:Eye scans detect signs of Parkinson’s disease up to seven... by jefozabuss on Wednesday August 23, 2023 @03:49AM (#37232984)
My friend's grandmother's hand started shaking badly eating soup and she got bedridden due to a fall in their home, 1 year later she started calling her daughter "nurse" because she didn't recognize her and passed away not too long after due to heart failure. I really hope they will find a treatment to this disease eventually.
Re:Eye scans detect signs of Parkinson’s disease up to seven... by 1234letshaveatw on Wednesday August 23, 2023 @08:57AM (#37235141)
I think "primarily" is overstating it. You don't just keep on truckin' with diminished motor control. It is degenerative and causes dementia
Re:Eye scans detect signs of Parkinson’s disease up to seven... by efitz on Wednesday August 23, 2023 @12:23AM (#37231859)
But what if you’re a false positive? What opportunities dis you forgo by choosing a path based on incorrect foreknowledge?
Re:Eye scans detect signs of Parkinson’s disease up to seven... by anonzzzies on Wednesday August 23, 2023 @12:29AM (#37231889)
As someone who is somewhat older and had a medical scare, I am going to say I wish I had done everything always as if I am going to die in a year.
Re:Eye scans detect signs of Parkinson’s disease up to seven... by OJFord on Wednesday August 23, 2023 @06:04AM (#37233806)
I can't really think of any significant short-term interests I have, I think if I (relatively young) was told I was going to die in a year, or otherwise decided I should heed this advice and live that way, I'd spend the year in depression. Or at best just closing out investments, selling things, etc. to make it easier for family to deal with. I just can't imagine thinking Oh right now's the time for that (quick) 'experience' I always wanted (because what?) - I could travel and eat & drink very well perhaps, but I think I'd just find it futile.

And yes I'm well aware this applies inductively to all of life, it's just somehow better if you don't know the value of N.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by anonzzzies on Wednesday August 23, 2023 @06:26AM (#37233904)
> I could travel and eat & drink very well perhaps, but I think I'd just find it futile.

I tried that and found it absolutely depressing and futile. Quick experiences never did anything for me or my family. But just doing what I like/want to do only (which not everyone can; some people seem to like/want things that cost a lot of money) is what I should've done for the past 40, not only the past 20 years is what I mean. Maybe dying next year is stressful for most, so make it 5 years; is that better? Or 7 as the article says?

Re:Eye scans detect signs of Parkinson’s disease up to seven... by darkclouds on Wednesday August 23, 2023 @08:26AM (#37234804)
> I wish I had done everything always as if I am going to die in a year.

But euthanasia as a non traumatic form of death unlike suicide, is still prohibitively expensive.

Crowdfunding steals your privacy.

Science steals your privacy, and can keep you alive for longer.

So are you not over rating life somewhat?

Re:Eye scans detect signs of Parkinson’s disease up to seven... by stubish on Wednesday August 23, 2023 @05:09AM (#37233512)
Alas, decisions need to be made today when hindsight is only available tomorrow.
Re:Eye scans detect signs of Parkinson’s disease up to seven... by justin66 on Wednesday August 23, 2023 @09:10AM (#37235308)
> If my mind is going to be gone in 10 years, I'm sure as shit not saving for long term retirement anymore.

But hopefully if you could get a Parkinson's diagnosis seven years prior to symptoms, you'd be able to save some money to keep from becoming a burden on your family later on.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by kadoban on Wednesday August 23, 2023 @02:43PM (#37240415)
There's other ways to avoid becoming a burden, but yes that would be worth planning for.
Re:Eye scans detect signs of Parkinson’s disease up to seven... by haldujai on Wednesday August 23, 2023 @12:09AM (#37231765)
I don't believe any disease modifying interventions exist which would suggest no, from a purely medical patient perspective at least.

There are some candidates advertised as promising but I'm not sure how much stock I have in this. This isn't my area of expertise but disease modifying therapies for neurodegenerative diseases have been touted as being "around the corner" since I was a first year medical student.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by JimtheCoder on Wednesday August 23, 2023 @12:04AM (#37231734)
If we could diagnose before actual Parkinsonian symptoms emerge, studying and developing preventative strategies and pharma will be a lot easier.

Parkinson's is funny in that sometimes what initially presents as Parkinsonian symptoms could develop into something like MSA over a span of 5 or more years. If this person were in a clinical trial for pure Parkinson's, it would sort of mess things up...

Re:Eye scans detect signs of Parkinson’s disease up to seven... by mensetmanusman on Wednesday August 23, 2023 @08:13AM (#37234664)
For insurance companies, yes.
Re:Eye scans detect signs of Parkinson’s disease up to seven... by TaupeRanger on Wednesday August 23, 2023 @08:52AM (#37235055)
To medicine, generally? Yes, because we could enroll patients in trials to look at prevention/delay of symptom onset. To patients right now? No, and probably a net negative, because the psychological harms from knowing what's coming would cause greater harm than the benefit of planning.
Re:Eye scans detect signs of Parkinson’s disease up to seven... by peterfirefly on Wednesday August 23, 2023 @12:25PM (#37238439)
Probably only for research at the moment.

I expect people will look into why eye scans work and how to make them work better.

I also expect them to use this to catch potential Parkinson's patients early and see if they can find out more about early stages of the disease. Maybe they'll find something that works even earlier than eye scans.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by ShamelessC on Wednesday August 23, 2023 @12:18AM (#37231831)
Neat! And they're VC backed too so you can be _sure_ that the minute that have a working product that makes a great impact on the world will be the minute that they sell out completely and sell all your data to advertisers or some shit.

Am I right?!

Just kidding I know people hate this sort of comment. "Ah, so cynical. Sometimes companies do good stuff!"

Not really though. I mean sure, one here or there. But on average? Nah. Particularly when VC's are involved!

Woo!! The world is burning!!

edit: This is going to get buried in the negative with downvotes, but to the person that upvoted this just now - I suspect you're a pretty rad person. That is all.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by ianbutler on Wednesday August 23, 2023 @12:37AM (#37231931)
[delayed]
Re:Eye scans detect signs of Parkinson’s disease up to seven... by ShamelessC on Wednesday August 23, 2023 @03:12AM (#37232749)
Ya got me there guy!
Re:Eye scans detect signs of Parkinson’s disease up to seven... by robertlagrant on Wednesday August 23, 2023 @03:49AM (#37232982)
> Sometimes companies do good stuff!

Obviously. Otherwise they wouldn't get paid for very long.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by orangepurple on Wednesday August 23, 2023 @04:53AM (#37233414)
That's not necessarily true. Major US corporations like DICK's are all aboard the woke train despite hemorrhaging customers massively from the second and third order consequences of banning scary things from their stores several years ago. To the tune of $250 million. And the CEO kept his job!
Re:Eye scans detect signs of Parkinson’s disease up to seven... by flir on Wednesday August 23, 2023 @06:00AM (#37233787)
https://www.statista.com/statistics/205758/net-sales-of-dick...

Not seeing much customer hemorrhaging in that graph.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by orangepurple on Wednesday August 23, 2023 @09:59AM (#37235987)
Surprising if true. How do you dig yourself into a $250 million hole with ever increasing net sales?
Re:Eye scans detect signs of Parkinson’s disease up to seven... by flir on Wednesday August 23, 2023 @11:48AM (#37237872)
In the UK, Wilko has gone into receivership because it's been borrowing at cheap rates, and the bill's just come due. It's widely believed that it's just the first of many.

No idea if that's what is happening with this company or not, I haven't chased any further than a revenue graph (and even that isn't from a source I trust much).

Re:Eye scans detect signs of Parkinson’s disease up to seven... by robertlagrant on Wednesday August 23, 2023 @06:55PM (#37242968)
Your expenditures beat your income.
Re:Eye scans detect signs of Parkinson’s disease up to seven... by playto on Wednesday August 23, 2023 @12:22AM (#37231852)
> say, eye movement slowness

It’s not just movement. Retinal tissue develops from the same embryonic tissue as the brain. They probably looked at structure, vasculature.

The best anecdote in this space- nobody with congenital blindness has developed schizophrenia.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by divbzero on Wednesday August 23, 2023 @12:41AM (#37231948)
> nobody with congenital blindness has developed schizophrenia

What’s the rationale for why this might happen?

Re:Eye scans detect signs of Parkinson’s disease up to seven... by tremon on Wednesday August 23, 2023 @09:10AM (#37235301)
You could posit that a necessary trigger for developing schizophrenia is (over)stimulation of the visual cortex. If that can't happen in blind people (I don't know if all blindness is the same), they'd be naturally protected without even having to consider a genetic component.

But to me, very low incidence rate for both seems like a sufficient rationale. Given that there's both viral and genetic causes for congenital blindness, it just doesn't make sense to imply the protection is genetic: even if true, there would still be cases of schizophrenia among the people that were blinded by a viral infection in-utero.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by i_cannot_hack on Wednesday August 23, 2023 @12:47AM (#37231982)
That anecdote is not necessarily true. The combination world be very rare even if blindness offers no protection, and it seems to simply not have been studied enough to be confident those rare individuals have been identified as such and published as case reports.

https://www.lesswrong.com/posts/z9Syf3pGffpvHwfr4/i-m-mildly...

Re:Eye scans detect signs of Parkinson’s disease up to seven... by srcreigh on Wednesday August 23, 2023 @01:00AM (#37232055)
It’s not an anecdote, it’s the idea that there are no anecdotes.

That is a much more risky idea in the first place, and your link provides quite a few such anecdotes.

Re:Eye scans detect signs of Parkinson’s disease up to seven... by po8tin on Wednesday August 23, 2023 @12:49AM (#37231993)
Tomorrow; new Worldcoin orbs with Parkinson’s detection!