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Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by a_bonobo on Monday July 31, 2023 @01:56AM (#36939252)
This is the code used in the paper:

https://gitlab.com/machine-biology-group-public/pancleave

>This package implements a scikit-learn-based random forest classifier to predict the location of proteoylytic cleavage sites in amino acid sequences. The panCleave model is trained and tested on all human protease substrates in the MEROPS Peptidase Database as of June 2020. This pan-protease approach is designed to facilitate protease-agnostic cleavage site recognition and proteome-scale searches. When presented with an 8-residue input, panCleave returns a binary classification indicating that the sequence is predicted to be a cleavage site or non-cleavage site. Additionally, panCleave returns the estimated probability of class membership. Through probability reporting, this classifier allows the user to filter by probability threshold, e.g. to bias toward predictions of high probability.

In the face of current hype around LLMs and 'fear of AI', calling a Random Forest Classifier 'AI' is a bit... far

Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by beeforpork on Monday July 31, 2023 @03:28AM (#36939695)
Every algorithm is now called AI, unfortunately. 'AI' is being used 'exponentially'.
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by wrp on Monday July 31, 2023 @04:40AM (#36940103)
Under current usage of the term, I think the bimetallic switch in my office thermostat qualifies as an AI.
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by IanCal on Monday July 31, 2023 @05:44AM (#36940426)
Random forests are absolutely AI as the term has been used for a very long time in academia and in public.
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by uoaei on Monday July 31, 2023 @01:22PM (#36945897)
I fear this kind of retconning will become more commonplace as new entrants to the space who are unfamiliar with the history of the field put words in the mouths of academics that academics themselves would vociferously reject.

Academics have long pushed back against the labeling of everything as "AI", and only the most public-facing ones with more than a buck to make on the hype treadmill ever stoop so low.

In academia, "AI" is usually reserved as a synonym of "AGI" in large part because of the fuzziness and lack of consensus around a good definition of "intelligence". The term is simply not applied to actual outputs of research because there's no way to justify calling anything "intelligence".

As the saying goes, what's the difference between ML and AI? ML is what the PhDs call it, AI is what the MBAs call it.

Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by IanCal on Tuesday August 01, 2023 @03:50PM (#36961673)
> In academia, "AI" is usually reserved as a synonym of "AGI"

Now this is retconning. I did my uni course called AI almost twenty years ago. The same processes had been called that for a long time.

Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by bluenose69 on Monday July 31, 2023 @04:38PM (#36948447)
Agree completely, particularly with the smirk I can see in the final word! As an academic, "AI" means "fund me". It's the new "big data". And "exponential" is the new "rising" (or, sometimes, "falling").
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by jjcon on Monday July 31, 2023 @04:02AM (#36939887)
The AI term has been coopted by Hollywood notions of synthetic human-level intelligence but it really is just referring to the academic discipline which Random Forests definitely falls under and has for decades.
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by a_bonobo on Monday July 31, 2023 @05:04AM (#36940221)
Yes I agree, but OP's link is not aimed at academics, it's aimed at the general public. And you can't expect the general public to know that distinction: they see 'AI', they think 'ChatGPT', not Random Forests
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by IanCal on Monday July 31, 2023 @05:44AM (#36940423)
AI has been discussed in public for years and was attached to huge numbers of things well before chatgpt. Chatgpt only came out less than a year ago.
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by nerdponx on Monday July 31, 2023 @07:14AM (#36940996)
We've also been using the term Machine Learning for a long time to try to avoid this. Using "AI" where "ML" would suffice is just trying to cash in on recent hype for clicks.

Still an interesting result of course.

Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by fluidcruft on Monday July 31, 2023 @08:47AM (#36941790)
My understanding is "ML" came into existence after the term "AI" became an untouchable and disrespectful dirty word in academia after a previous hype cycle went bust. Statisticians wouldn't be caught dead working on "AI". See also xkcd purity scale (435).
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by Kye on Monday July 31, 2023 @10:00AM (#36942579)
It looks like machine learning took over in the 2010s after a long convergence starting in the 2000s.

https://books.google.com/ngrams/graph?content=artificial+int...

This is from published books, so probably less affected by popular narratives. For that, we have Google Trends!

It looks like they trade places repeatedly when constrained to news searches: https://trends.google.com/trends/explore?cat=5&date=all_2008...

Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by nerdponx on Monday July 31, 2023 @10:12AM (#36942779)
Right. ML is less likely to arouse emotions in either direction.
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by 6D794163636F756 on Monday July 31, 2023 @05:04PM (#36948794)
It's also a refinement on the term. AI can include a lot while ML is much more specific.
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by jjcon on Tuesday August 01, 2023 @02:51AM (#36953127)
Not really though it may seem that way. Not all AI is ML. There are a ton of things within AI such as planning algorithms or Expert Systems. Again those are under the academic discipline of AI but not in the subfield of ML.
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Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by antegamisou on Monday July 31, 2023 @08:32AM (#36941648)
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Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by jeroenhd on Monday July 31, 2023 @07:49AM (#36941252)
A random forrest classifier is a classic example of AI, quite popular before hardware caught up with the computational needs of neural networks.

Random forests of significant size also suffer some of the same inexplicability problems that neural networks suffer from, so it makes even more sense to make the comparison.

Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by fodkodrasz on Monday July 31, 2023 @07:49AM (#36941253)
At a job where the company specialized in mathematical optimizations (think operations research, logistic planning, timetable optimization, etc.) we jokingly called the solvers with heuristics "A.I. technology, short for Advanced If technology". Some customers got the joke, some didn't, but they were generally content with the results :)
Re:AI search of Neanderthal proteins resurrects ‘extinct’ an... by selimthegrim on Monday July 31, 2023 @08:26AM (#36941575)
Now the question is, could this be done for stuff like marine immune genomes?