Psychological issues often stem from mitochondria not working properly, i.e. neurons not having enough energy to work well. Fix mitochondria and many psychological problems disappear.

See e.g.:

https://pubmed.ncbi.nlm.nih.gov/18979198/

https://www.quantamagazine.org/mitochondria-may-hold-keys-to...

what makes you think that your mitochondria isn't working properly. reading this it sounds like your throwing a bunch of supplements at something and hoping something else happens. it doesn't sound very scientific.

Did you read the second link?

I don't think that justifies saying its often mitochondira. it doesnt explain why in the first place. it sounds like the depression is caused by an chemical imbalance thing. i dont think you can make sweeping judgements like that and say something like just take some vitamins and youll be cured

OP talked about burnout which is seen as a lack of mental energy. Mitochondria would be the first thing to look at when it comes to energy as it's a "power plant" that makes cells work.

I think you should read a little of what burnout actually is instead of supplement pseudoscience

You are accusing me of following pseudoscience yet I am the only person in this conversation to actually post scientific links...

You already expressed you don't understand what causes burnout and what experience is like. It's not just mental energy. Go read about mental health and how people actually experience. I'm not here to educate you

Could you please stop posting unsubstantive and flamewar comments? You did that quite a bit in this thread and unfortunately have been doing it elsewhere too. It's not what this site is for, and destroys what it is for.

If you wouldn't mind reviewing https://news.ycombinator.com/newsguidelines.html and taking the intended spirit of the site more to heart, we'd be grateful.

Did someone go through my post history and just flag a bunch of posts?

This guy is giving out mental health advice based on not understanding what he is talking about. I think that is dangerous and isn't a place for being polite.

Yes, I did, because you've been breaking the site guidelines. We need you to follow HN's rules regardless of how wrong someone is or you feel they are. Could you please review https://news.ycombinator.com/newsguidelines.html and stick to them going forward? We'd appreciate it.

Even for unsubstantiated health claims and telling people to go and take unknown supplements? Would you prefer a comment like that gets flagged?

I get the guidelines for inconsequential topics, but pretending something is valid when engaging with something that could be harmful seems like its elevating its legitimacy. In this case there is plenty of reading to do on the topic of burnout causes.

I guess the simplest answer from you would be the answer to this question. If i posted something encouraging people to not take vaccines, how does that discussion get handled? Does every comment and thought really get treated equally with curious responses? I guess to me it seems fair to, be short direct and point out the misinformation even if it appears to be flaming

Yes, the guidelines cover this: "Don't feed egregious comments by replying; flag them instead."

https://news.ycombinator.com/newsguidelines.html

I see got it.

Anyway stuff like this https://greatergood.berkeley.edu/article/item/six_causes_of_...

is why suggesting taking supplements to cure burnout and dropping an irrelevant link to a study about mental illness is uninformed.

I'll hit report in the future then, thanks for the back and forth and explaining.

I think you might find this article relevant:

https://www.lesswrong.com/posts/fFY2HeC9i2Tx8FEnK/luck-based...

Fixing psychological issues with supplementation can sometimes be like trying to apply a bandage to a cut on your nose while somebody repeatedly punches you in the face. You should apply the bandage, but it's not going to do much good until you stop getting hit in the face.

Alternate take: get your energy levels and body function in order first and then face whatever problem you have.

Supplementation can also work wonders. There is literray almost zero downside to it except wasting money. So if you have some money to waste, start experimenting.

The above advice is solid, but I would add number of others. CoQ10, C in multiple forms, ALCAR, D, Bromelain, concentrated fish oil, etc.

Personally i'm convinced they work. If and only if you believe in the working of supplements.

I am also convinced they do not work for me, because of the premises.

What is amazing is you dismissing the entire domain of the science with a single unsubstantiated sentence. Feel free to read some schoolar journals and research papers, rather then popular zines, if that is not too much trouble...

If you could fight deficiency with a mind, we would not have deficiency disesases.

I'm only speaking from experience.

> If you could fight deficiency with a mind, we would not have deficiency disesases.

That is so true. The thing is, a lot of diseases get treated as a deficiency disease.

Experience is highly overrated. Some stuff may work for you some not, depending on your current state (dynamic thing, daily changing). Many stuff you can't experience but you must measure.

Science is important. In accute phase response deficiency is the norm, as one example.

Vitamin B1 won a Nobel Prize in 1929 and solved a major generational illness in Japan. Lack of vitamin B3 has the same symptoms as schizophrenia (look up pellagra) and many people are misdiagnosed with it instead of tested for low brain B3 or genetic defects leading to lower absorption of B3.

> There is literray almost zero downside to it except wasting money.

And/or nasty interactions with prescription drugs when you do it incorrectly.

And nasty depletions due to some drugs when you do it correctly - NSAID against C, beta blockers against CoQ10 etc...