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A comment on Study: Electroshock therapy more successful for depression than ketamine. Parent comment

Re:Study: Electroshock therapy more successful for depressio... by boredtofears on Monday October 24, 2022 @03:58AM (#33314025)
> The day after an acid trip isn’t a new neurochemical environment because of the powerful hallucinations the day before, it is something else

What is a "new neurochemical environment" exactly? I've had many acid comedowns, and they have all been affected by how the high was - emotionally, mentally, and physically. What do you mean by "its something else"?

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Re:Study: Electroshock therapy more successful for depressio... by tekknik on Monday October 24, 2022 @08:55AM (#33316023)
I’m far from an expert here, but as I understand it there is no repeated, or daily dose of the psilocybin. Instead it physically changes your brain. Here’s one study:

https://www.mdpi.com/1422-0067/22/2/835/htm

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Re:Study: Electroshock therapy more successful for depressio... by novok on Monday October 24, 2022 @02:06PM (#33320178)
IMO I think it is still a new neurochemical environment, much like how the body is different after intense exercise for the next few days, as it recovers. It gets sore, weaker, etc. There is definitely a training & depletion effect for the brain.
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