Vaccine are building an immune response, they're not drugs that try to cope the symptoms (eg. Panadol) and they are the safest drugs out there.
Is so interesting how people eat Panadol and many other drugs like candies (without reading the KNOWN side effects - which are also nasty), while they focus so much on things they know nothing about thinking that has mysterious "long term effects"
I strongly doubt that Acetaminophen would be approved as an OTC drug if proposed today.
> He died at a hospital in Seattle. His wife, Cindy Engstrom, said he had injured one of his feet in October, accidentally took too much Tylenol for pain relief and suffered liver damage.
Once I realise that the Flu (or whatever) is inducing enough pain that I can't ignore it, or I start to run a serious fever, I take paracetamol to get on top of that, usually in the form of Lemsip because I'm bad at taking pills, Lemsip is cheap, and none of the other ingredients in ordinary Lemsip these days really do anything much, just the paracetamol.
I find maybe 1 or at most 2 of the "maximum" 1g (= 1000mg) doses a day gets the job done, which is well inside the indicated limits.
None of the OTC alternatives do it for me, they're not useless but the effect from the indicated dose is far reduced so I'm glad to have paracetamol. I've had fentanyl after surgery, which was certainly effective but seems like a very bad idea to have around the house, and Entonox after a road accident which again, effective but seems like a bad idea for OTC usage.
Popping NSAIDs multiple times a week on a regular basis is definitely not good, and yet the same people who do that are often afraid of vaccines.
People are seriously clueless about relative risks.
I'm not saying Advil is dangerous, I'm saying people significantly overestimate the risks of vaccines.
If you're concerned about vaccines but not about other common drugs, you're in need of some risk calibration.
The good news is that I am not concerned about the safety and efficacy of vaccinations. I misinterpreted your comment because of the way it was worded. This is because I know some over the counter pain medications, like Tylenol, can be dangerous. So, I assumed there was a risk to Advil that I wasn't aware of and wanted to know more, given your background as a Biochemist.
Also, NSAIDs are shown to slow healing from injury in most cases.
Ibuprofen is terrifically useful but also a little scary for something we use so routinely.
e.g. some parents gave their 7 year old a motrin, and all her skin sloughed off her body and she had brain damage and lost 80% of her lung function.
https://www.cbsnews.com/news/jury-awards-63m-to-samantha-rec....
And fatal anaphylactic reactions to vaccines aren’t atypical.
My point is not that Advil is particularly dangerous, my point is that people dramatically overestimate the dangers of vaccines.
Look at Vioxx. It took 4 years on the market before anyone realized it increased the risk of heart attacks.
Advil has been around for decades. It has known risks.
I have all three vaccine doses too, I’m not saying don’t take the vaccine, I’m saying Advil has a more robust safety profile.
Other drugs don't have a better safety profile if they were tested for so long. If anything, it proves that is highly toxic for your body (similarly to many chemio treatments)
Covid has been around for 2 years. The vaccines for 1 year. We don’t know the long term effects of either.
Vaccines were trialed for dengue fever that made the disease worse. Vaccines are NOT “the safest drugs out there”.
Anyone who says “the vaccines are the safest drugs out there” is just lying or incompetent.
The risk of an autoimmune disorder may not show up for years.
Our data collection right now is garbage and it’ll take years to sort through.
"Autoimmune disorder" probably have a very low correlation and if anything vaccine have saved the life of many, more than any other drug.
- This isn't really the reason why mRNA is attractive here (see my other comment above). (Though, ability to iterate/try many protein combinations quickly in animal models was helpful).
- Almost no drugs or treatments do we really know the long term picture of. Running studies in a way that lets you detect effects far later in life isn't practical.
- When we're talking about treatments to prevent severe disease, bounding the consequences to be very, very likely to be well below the consequences of the virus times the likely infection chance is "good enough".