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Re:An Experience with Modafinil by ei8htyfi5e on Monday January 24, 2022 @11:09PM (#30067883)
I took it heavily in grad school. Prescribed off label for adhd. You can be in any state of exhaustion, take a modafinil, and an hour later feel like you just woke up on a Sunday morning after sleeping in. It’s nuts. The military uses it for fighter pilots. You can take it for days and only lose minimal amounts of reaction timing. At my peak, I stayed up for finals for a week straight with maybe 2 hours of sleep total. Don’t lecture me, I know.

Anyway, it took 2 days in bed for me to recover after. Brutal.

Towards the end of that time period, my brain stopped processing information in the 30 degrees at the edge of my peripheral vision on either side. We were at a restaurant celebrating being done and the waiter kept teleporting into view at around 60 degrees off my center line. Very startling. Done with it now since I don’t have anything nearly that stressful in my life, but back then, it was a godsend.

Modafinil has a 15 hour half life so my main complaint was my sleep schedule was about 26-28 hours so I was constantly shifting. Adrafinil is only the active isomer in modafinil so it’s more potent. I didn’t like it as much. Even at a half tab it still kept me up longer than modafinil. Also modafinil makes your pee smell when it’s metabolized whereas adrafinil not nearly as much.

Re:An Experience with Modafinil by marcan_42 on Monday January 24, 2022 @11:17PM (#30067944)
Am I the only one thinking there is something seriously wrong with an education system if students have to resort to drugs that keep them awake for a week to succeed in it?

I mean I'm not exactly anti-medication but... wow.

Re:An Experience with Modafinil by brimble on Monday January 24, 2022 @11:28PM (#30068011)
"Have to", maybe not. Will perform better if they do, probably. Will be outcompeted by others if they don't, many of whom only did better because they used drugs, yes.

It took me half a lifetime to really come to grips with it, but fact is, winners absolutely do use drugs. William S. Sessions' anti-drug arcade game ads lied to me.

Re:An Experience with Modafinil by mise_en_place on Tuesday January 25, 2022 @01:11AM (#30068736)
Be careful with this line of thinking. It can lead you to justify some extremely unhealthy habits. You'll justify it by saying it's fine, you're getting things done. But the cost will always be there, either physical or mental.
Re:An Experience with Modafinil by brimble on Tuesday January 25, 2022 @01:35PM (#30075943)
Don't worry, I'm still taking it pretty easy. I'm just not surprised when I see someone who's very successful and seems far more alert and energetic than I could possibly be without some serious uppers—mystery solved, they're very probably on some serious uppers.
Re:An Experience with Modafinil by mellavora on Tuesday January 25, 2022 @06:43AM (#30070740)
Agreed and note that 3 of 4 paragraphs in ei8htyfi5e's post were describing the costs:

> Anyway, it took 2 days in bed for me to recover after. Brutal.

> my brain stopped processing information in the 30 degrees at the edge of my peripheral vision on either side.

> makes your pee smell

Re:An Experience with Modafinil by Zababa on Tuesday January 25, 2022 @07:54AM (#30071222)
On the other hand, the cost of not using those things can be not getting a good job, or not being able to do your job, which has costs too. A small difference in work done can be the difference between keeping a job and getting fired.
Re:An Experience with Modafinil by marcan_42 on Tuesday January 25, 2022 @12:34AM (#30068499)
Maybe school shouldn't be a competition with winners and losers.
Re:An Experience with Modafinil by xboxnolifes on Tuesday January 25, 2022 @01:10AM (#30068724)
School is just a part of life, and life has limited resources. There will always be winners and losers. At least, until (and if) we reach a point where the total sum of resources exceeds the total demand for them.
Re:An Experience with Modafinil by pfortuny on Tuesday January 25, 2022 @03:25AM (#30069528)
Is the score what makes a student a winner, though? That is what parents have to learn to curb.
Re:An Experience with Modafinil by xboxnolifes on Tuesday January 25, 2022 @10:10AM (#30072605)
The score is supposed to be representative of your knowledge in a subject. And the entire point of going to school is to become more knowledgeable in a subject so you can apply it somewhere in your life.

If the score was not an indicator, then it serves no purpose.

Re:An Experience with Modafinil by marcan_42 on Tuesday January 25, 2022 @11:45PM (#30081827)
Unfortunately, academic scores in most of the world stopped representing knowledge and started representing rote memorization long ago. They are a very, very poor indication of knowledge.
Re:An Experience with Modafinil by pfortuny on Wednesday January 26, 2022 @10:42AM (#30086822)
Well, if success in life is measured by getting the highest score, then we are really doomed.
Re:An Experience with Modafinil by ei8htyfi5e on Tuesday January 25, 2022 @02:11AM (#30069061)
Maybe most schools but I went to the top school (most years) so it was. …and I had imposter syndrome, so I did everything I could to keep pace.
Re:An Experience with Modafinil by krageon on Tuesday January 25, 2022 @06:05AM (#30070500)
Capitalist life is a competition with winners and losers. The losers are basically debt-slaves, and the winners are modern royalty.
Re:An Experience with Modafinil by mannerheim on Wednesday January 26, 2022 @12:42AM (#30082204)
Capitalism has nothing to do with it. Schooling in China is and was even more competitive, making competition in American schools look like child's play. This was the case even before China opened up and introduced market reforms in the 90s.
Re:An Experience with Modafinil by CountDrewku on Tuesday January 25, 2022 @09:11AM (#30071950)
ALL LIFE is competition regardless of whether it's capitalistic or not. People need it or they're miserable. Competition is not a bad thing.
Re:An Experience with Modafinil by akimball on Tuesday January 25, 2022 @11:01AM (#30073308)
Competition is a bad thing when it squeezes out cooperative strategies with superior outcomes. This can be expected to be more frequent in a society perfuse with pro-competitive and anti-cooperative incentives. Competition is conceptually aligned with defection strategies. The fitness landscape generally has fragile optima at cooperative strategies. That said, competitive substrategies may contribute to the beneficial outcomes of a cooperative superstrategy of which they are a part.

Not all life is competition. Ecosystems in general are a complex web of cooperation. One could say that all life is cooperation with equal merit.

Re:An Experience with Modafinil by CountDrewku on Tuesday January 25, 2022 @11:17AM (#30073598)
Yes, it's a sliding scale like everything.

The idea that competition should not exist and is some outcome of "evil" capitalism is absolute ridiculousness. I was responding directly to that asinine comment.

Life without competition doesn't exist, nor should it.

Re:An Experience with Modafinil by krageon on Tuesday January 25, 2022 @11:07AM (#30073440)
Maybe all of your life is competition, but mine certainly is not. It's an unhealthy attitude to have in your private life as far as I'm concerned.
Re:An Experience with Modafinil by CountDrewku on Tuesday January 25, 2022 @11:14AM (#30073540)
I did not say all my life is competition, it was a generalization that life cannot exist without competition. Reading comprehension bud.

It's a natural attitude that's innate to human survival. You need competition or you will be a miserable mentally unhealthy person. You're in denial if you don't realize this truth.

This ridiculous socialist utopia where everyone is at peace doing finger painting all day doesn't exist. It's a good way for your society to collapse though. Competition is not some artificial outcome produced by capitalist economic systems.

Re:An Experience with Modafinil by adrianN on Tuesday January 25, 2022 @01:09AM (#30068722)
That is impossible because there is limited supply of the things you want to achieve with your education, e.g. a tenure track position, and the demand is always higher than the supply.
Re:An Experience with Modafinil by bryan_w on Tuesday January 25, 2022 @02:15AM (#30069088)
Shhh don't tell them, let them stay unambitious. It makes it easier for the rest of us.
Re:An Experience with Modafinil by akimball on Tuesday January 25, 2022 @11:06AM (#30073423)
This is true only if your range of available strategies is constrained to a closed competitive subsystem. The actual range of available strategies is unbounded, given unlimited rationality.
Re:An Experience with Modafinil by gunshai on Tuesday January 25, 2022 @12:07AM (#30068314)
I hate that I feel so congruent with this comment.
Re:An Experience with Modafinil by torginus on Tuesday January 25, 2022 @07:25AM (#30071012)
My favorite thing is more often than not, the faces of anti-drug campaigns tend to be celebrities/athletes who were caught in a drug scandal, and do this campaigning to improve their public image.

Arnold Schwarzenegger is a prominent example.

Re:An Experience with Modafinil by majormajor on Monday January 24, 2022 @11:31PM (#30068037)
Cramming is less "required" then "an alternative way to get a good grade than working all semester long."
Re:An Experience with Modafinil by ei8htyfi5e on Tuesday January 25, 2022 @02:16AM (#30069095)
It wasn’t a paper test and cramming. I had to create a product from scratch. I could have made a simpler product but I’m type a and challenged myself. 3D modeling, waiting for a 3D printer to complete, designing and manufacturing creating circuit boards, programming them, setting up a server, modifying the printed case by hand to insert glass, iterating when tolerances aren’t right. …it was a lot of work.

But now I get to make cool shit for a living.

Honestly believe if you give me enough time and money I can make anything. Worth it.

Re:An Experience with Modafinil by marcan_42 on Tuesday January 25, 2022 @03:03AM (#30069384)
> Honestly believe if you give me enough time and money I can make anything. Worth it.

Same, but it didn't take a week on modafinil to finish a crazy project for me, I just always just liked making cool shit ever since I was a kid. Currently more on the software/kernel side, but I've done my share of hardware projects.

For me, after bouncing around a few universities, I realized how much of a broken joke the system was and resolved to go the easiest route to get the piece of paper (an on-line university), which I'm glad I did because the one time in my life I needed it it was important... but uni never taught me anything I couldn't have learned more efficiently on my own.

I distinctly remember that time in a microcontrollers class where the book was wrong and teaching the exact opposite of the solution to the problem it was trying to teach, and I'd known about that one for like 7 years at that point, and when I offered to the teacher to write a little article about it so we could all learn about it, he said yes and never even read it...

Or that time where as a sophomore I was helping a team of seniors working on a project to build a CubeSat, and I designed the PCBs and all the firmware and we won the competition to get funding and actually launch... and the uni's response was to kick us out of the lab we were in because "we were using too much space" (about 1m of desk space there). That CubeSat never launched.

Also, there was one part of that board designed by a professor instead of me. It was the only part that didn't work. And I thought it was dodgy at the time, and with my current experience I can confidently say that design was utterly insane and broken and he had no idea what he was doing.

Meanwhile in Calc II they wanted me to memorize three dozen identities because... why? I liked math until I got to that class, because even though it wasn't exactly being taught in an engaging way, I could work out the underlying concepts and understand and appreciate it, and work from first principles. Then it got complicated enough that doing that at the exam was no longer viable and I was just expected to become a computer and memorize all the damn formulas (and it wasn't just a few), understanding be damned. I cheated my way through that exam ("yes professor, I promise this TI-84 emulator on my Zaurus PDA is exactly like the real thing and I don't have a little formula database app in another window"). I damn well know what integration is and how it fundamentally works and how to apply it, but storing rote trivially looked up information is what we have paper and computers for. I don't go around memorizing programming APIs, I look up what I need and whatever I use often enough comes naturally.

Chemistry was more fun. We were allowed one index card, handwritten, both sides for the exam. I developed an electrical arc sharpening mechanism for mechanical pencil lead, so I could handwrite it all in 4pt size or so. Give me limitations and I will make the best use of them :)

Yeah, the system is broken.

Re:An Experience with Modafinil by WalterSear on Monday January 24, 2022 @11:36PM (#30068062)
I had multiple classes in university where the professor didn't finish their syllabus for the term and so the TAs crammed the last few weeks worth of class into a study session.
Re:An Experience with Modafinil by bbreier on Tuesday January 25, 2022 @12:51AM (#30068608)
I definitely remember approximately weekly having to stay up all night to finish my regular assignments assigned the same day and due the next
Re:An Experience with Modafinil by echelon on Monday January 24, 2022 @11:53PM (#30068181)
Some students have ADHD or simply learn in a way that does not track with how school and university are taught. The rewards and incentives are typically orthogonal to what a person diagnosed with ADHD wants, and often times extreme measures must be taken to adapt to the rigid expectations.
Re:An Experience with Modafinil by marcan_42 on Tuesday January 25, 2022 @12:33AM (#30068493)
That is a failure of the system to adapt to the needs of students. I have adult-diagnosed ADHD and school sucked for me too... and I'm on medication now, which makes me function normally, not stay up for a week.
Re:An Experience with Modafinil by mlac on Tuesday January 25, 2022 @07:39AM (#30071110)
I’ll never forget that I was sitting outside the hallway before my SATs, and some random girl I just met offered me Adderall - I had 3 thoughts:

1) I’m not taking random pills from a stranger, let alone before the SATs

2) If it is adderall, I have no idea what it would do to me

3) If I need adderall to do well on the SATs that would get me into a better college, I’m going to need it through college

Seeing this story makes me think that, yeah, some people probably do make it through hard programs with medication…

Re:An Experience with Modafinil by PragmaticPulp on Tuesday January 25, 2022 @01:38AM (#30068874)
Definitely don’t have to. It’s an anecdote from a single person, it’s not normal behavior.

Don’t read too much into individual HN comments, especially those describing outlier behavior.

Re:An Experience with Modafinil by Bancakes on Tuesday January 25, 2022 @02:03AM (#30069001)
How about kids don't procrastinate and play videogames?
Re:An Experience with Modafinil by kfarr on Monday January 24, 2022 @11:27PM (#30068004)
It’s worth it, no faster way to get into lifelong debt!
Re:An Experience with Modafinil by jack_pp on Tuesday January 25, 2022 @01:08AM (#30068712)
Different effects on different people I guess. Whoever is reading parent, don't expect this to be true for you. It certainly wasn't for me.. if I didn't get proper sleep and then took modafinil I would get super anxious, fidgeting and just plain feeling bad. Certainly couldn't work on it.
Re:An Experience with Modafinil by samatman on Tuesday January 25, 2022 @08:49AM (#30071723)
Small correction: adrafinil is a prodrug to modafinil and is less potent, it turns into modafinil after liver action. It also makes your pee smell more, if anything.

I expect you're thinking of armodafinil, the isolated r-isomer. I've taken it a few times, it's more potent by weight than modafinil but I'm unconvinced the chiral group is anywhere near so decisive as it is with amphetamine, where the laevo-rotary molecule is useless unless you have a head cold.

Re:An Experience with Modafinil by ei8htyfi5e on Tuesday January 25, 2022 @11:02AM (#30073335)
This is 100% correct. I’ve never taken adrafinil, late night typi.
Re:An Experience with Modafinil by nojs on Tuesday January 25, 2022 @12:06AM (#30068304)
> I stayed up for finals for a week straight with maybe 2 hours of sleep total

I’m confused when I read anecdotes like this. Are you staying you literally slept for 2 hours over the course of 7 days, averaging 17 minutes of sleep per night for a week? I think that’s very unlikely!

Re:An Experience with Modafinil by oceanghost on Tuesday January 25, 2022 @01:02AM (#30068678)
It's possible but unlikely. You physically cannot sleep on these drugs without something like clonazepam. So I have no doubt a series of bad decisions could lead to someone being up that long.

However,

psychosis usually sets in around ~96 hours of sleep deprivation. It is however possible that this individual is unique or resistant, or maybe just his youth helped him. When I was 16 and MTV still played music-- I could survive on 2hrs sleep a day for weeks.

Re:An Experience with Modafinil by r_hoods_ghost on Tuesday January 25, 2022 @01:09AM (#30068716)
I'm sorry, this is rubbish. One of the reasons Modafinil is useful is that it will help you stay awake and alert for long periods AND when you want to sleep you still can do. It isn't like speed.
Re:An Experience with Modafinil by Apfel on Tuesday January 25, 2022 @08:12AM (#30071383)
Yeah, I'm afraid you're definitely wrong on this. I've used Modafinil extensively at several different doses. Even at a quarter pill (50mg) you will struggle to feel even remotely tired if you take it after 9am (assuming you go to bed at a normal-ish time).
Re:An Experience with Modafinil by px43 on Tuesday January 25, 2022 @11:18AM (#30073615)
You should probably be saying "I" instead of "you". Anecdotally, I've never had trouble going to sleep even a couple hours after having modafinil. If anything, it's a more peaceful transition to sleep too. Modafinil makes me feel relaxed and refreshed. Like going to bed after taking a shower, or being in a hot tub or something.
Re:An Experience with Modafinil by krageon on Tuesday January 25, 2022 @06:08AM (#30070515)
It is categorically impossible (for me) to sleep on Modafinil, or it is at least significantly harder than on amphetamines (which I'll grant you can sleep on... Sometimes).
Re:An Experience with Modafinil by oceanghost on Tuesday January 25, 2022 @01:10AM (#30068730)
You know not of what you speak.
Re:An Experience with Modafinil by r_hoods_ghost on Tuesday January 25, 2022 @02:19AM (#30069116)
~15 years of taking Adrafinil and then Modifinil on prescription and "recreationally" says otherwise. The actual effect of a drug and then the psychosomatic effect of those who expect it to have a certain effect are two very different things.
Re:An Experience with Modafinil by netizen-936824 on Tuesday January 25, 2022 @05:49AM (#30070416)
Also, not everyone is the same neurologically. People seem to write off this difference as moot. It's not
Re:An Experience with Modafinil by torginus on Tuesday January 25, 2022 @07:27AM (#30071030)
You may have developed a tolerance.
Re:An Experience with Modafinil by RankingMember on Tuesday January 25, 2022 @10:12AM (#30072628)
> You physically cannot sleep on these drugs without something like clonazepam.

Please tell my brain this. Around 50% of the time my ADHD meds (Adderall) make me sleepy because, for once, my brain is calm and focused and it's a very relaxing experience as opposed to my typical state.

Re:An Experience with Modafinil by oceanghost on Tuesday January 25, 2022 @03:49PM (#30077823)
That just means you have real ADHD. Stimulants can have the opposite effect on people with ADHD.
Re:An Experience with Modafinil by RankingMember on Wednesday January 26, 2022 @10:00AM (#30086264)
We're in agreement there. Your original statement did not have this caveat.
Re:An Experience with Modafinil by jack_pp on Tuesday January 25, 2022 @01:10AM (#30068729)
I've once given it to a friend without telling him what it was exactly and he sure did sleep through it, he said he didn't feel anything at all and he was up from the night before (was in vacation). Asked him how he felt afterward and he reported no issues sleeping a couple of hours after taking it.
Re:An Experience with Modafinil by papandada on Tuesday January 25, 2022 @07:26AM (#30071014)
This seems to be a ... trusting and open-minded action on the part of your friend, might be one way to put it
Re:An Experience with Modafinil by jack_pp on Tuesday January 25, 2022 @07:35AM (#30071086)
We were young and yes, he did trust I wouldn't give him poison. I certainly didn't have a reputation of using illegal drugs, he knew I dabbled with supplements like Piracetam / Ashwagandha etc.
Re:An Experience with Modafinil by ei8htyfi5e on Tuesday January 25, 2022 @02:08AM (#30069034)
Yes. I slept for 2 hours on Wednesday under my desk on a camping pad. You don’t have to believe me. If anybody on HN ever outs me, there were a lot of people who can corroborate this.
Re:An Experience with Modafinil by argc on Tuesday January 25, 2022 @12:09AM (#30068329)
probably a slight exaggeration
Re:An Experience with Modafinil by thePostFuturist on Tuesday January 25, 2022 @12:18AM (#30068390)
The rumour is Limitless (the movie with Bradley Cooper in the early '10s) was modeled on Modafinil, the side effects being "inspired by" as well. I didn't have the peripheral vision failures to register, but the death like fatigue is real.
Re:An Experience with Modafinil by octoberfranklin on Tuesday January 25, 2022 @01:11AM (#30068732)
Limitless is the film version of Alan Glynn's book The Dark Fields. It was published in 2001, so it would've been written before or at most a year or two after modafinil got FDA approval, and long before modafinil was popularized by Wired, etc in the mid-2000s.

https://en.m.wikipedia.org/wiki/The_Dark_Fields

The book is really, really good. Much darker than the film, however. The ending is completely different, particularly the implications of the last paragraph.

If you're on a Dark Fields kick, Ted Chiang's 1991 short story Understand is worthwhile. Geekier and not as philosophically weighty, but way more fun.

Re:An Experience with Modafinil by jasonladuke0311 on Tuesday January 25, 2022 @11:19AM (#30073626)
> Ted Chiang's 1991 short story Understand is worthwhile.

Great story, as are most of his. It reminded me of the Dark Forest Theory [0] from the Remembrance of Earth's Past trilogy [1].

[0] https://bigthink.com/surprising-science/the-dark-forest-theo... [1] https://en.wikipedia.org/wiki/Remembrance_of_Earth%27s_Past

Re:An Experience with Modafinil by throwawayke on Tuesday January 25, 2022 @08:31AM (#30071554)
I take 200mg every morning. I can still have a midday nap.

I'm not narcoleptic but somehow it just doesn't work that well for me.

Dexamphetamine worked but ooh boy the side effects like munting.

Re:An Experience with Modafinil by musicale on Tuesday January 25, 2022 @02:16AM (#30069093)
Does skipping sleep during finals affect your ability to recall the material long term?
Re:An Experience with Modafinil by ei8htyfi5e on Tuesday January 25, 2022 @02:32AM (#30069185)
I had to make something. It wasn’t a cramming session. If it was a mental task, I would have taken a different approach. But I needed more hours and I got them.