They looked at 25 "averse events", and only half of them (12 of the 25) had higher prevalence with the vaccine than in the control group, which is what "no difference" looks like. The normal way you protect against this is by adjusting for the fact that you're doing multiple tests (one for each of the 25 adverse events), but "As is standard practice for studies of safety outcomes, no adjustment for multiple comparisons was performed.". Am I missing something?

Or to put it differently, if the vaccine puts you at risk for intracranial hemorrhages, does it also protect you against acute kidney injury (irrespective of Covid)? The difference is just as big in the other direction.

I'm starting to think that we should redesign all the older vaccines to be more like those ones.

But the risk of getting COVID in any time period is less than 1 (based on % of population that has actually had it, possibly less than 0.1 or 10% per year), so it's worth waiting for the safest vaccine for certain groups.

Given it's not slowing down, the likelihood of getting covid is actually quite high over time.

The Scandinavian solution will likely be to just delay vaccination for a week while a dose of the Pfeizer vaccine is tracked down. The change of contracting covid in that timeframe is very small.

These ethical considerations are necessarily local.

https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/burd...

Personally, I've effectively been self-isolating since January. Why should I get a shot now? Especially if it's going to wear off in 5 months?

Without a more detailed case behind this it feels like "just trust us".

I'd really like some trust but verify. The lack of ability to verify many of these directions, especially with some of them from different organizations contradicting each other, is bothersome.

While that's both vaccines, it's still quite rare especially given the large population size (2.3M people), especially considering for under 16s your risk of myocarditis is 37x more likely if you get Covid [2].

[1] https://jamanetwork.com/journals/jamainternalmedicine/fullar...

[2] https://www.aappublications.org/news/2021/08/31/covid-myocar...

In a world where people like to talk about their opinions, it's great to have some form of foundation. When I speak to folks and can talk about these details it often sways opinions on those who aren't at the extremes. I wish more people shared data and the foundation for their opinion.

I doubt that it would be 0/2M