There are plenty of other words (including adjectives) that you can use as honorifics - you've got Little John (and Lil Jon), Short Bob and Tall Bob.
I think it's fair to move away from Mr. and Mrs. being as prominent as they are.
One of the two nouns is an appositive, but it's never been too clear to me which is which in English grammar. In my native tongue it definitely doesn't seem to be the case that Mr. modifies Smith, as our equivalent to Mr. is a common noun that is used to refer to any male human.
There is a real gap in the archaic forms of Romance languages when it comes to the level of gender sophistication that was in the even more archaic Latin.
Modern languages are evolving rapidly and it is entirely within the realm of reasonableness to expect that humanity will tend towards meta-evolving it’s own languages.
But I am not well read in linguistics and suspect that Noam Chomsky has already written a book on this topic.
MY MISTAKE: apparently the law does allow a doctor to say no for his believes. I cannot edit the previous post.
Again, so this people today say that you have to say "les", what prevents me from saying I am not filling included, I want everybody to start saying "lus" or "chimichangas" for that matter? The problem for me is that they force you to behave however they want you to behave.