LMAO, this was really funny. I did not really think of it as blind I just wanted to remove confirmation bias. I saw so much of that at goop. I have no formal training and I just learn on the fly and try to execute. I have no doubt there are better and smarter ways, I would love critical feedback here or via email.

I'm not sure I have any useful advice; I get the impression you're doing incredibly well for someone with no formal training. On the one hand you might benefit from someone with a more rigorous background helping you avoid known non-obvious risks, but on the other hand almost all such people are going to run screaming because your risk tolerance is way higher than theirs. Having a chronic condition for which the existing treatments are inadequate really sucks. I wish you luck and safety.

(For the "era of higher risk tolerance", the good old "Ignition!" by John D Clarke is a fun read from the era when the official US rocket fuels programme consisted of just lighting stuff on fire and seeing what happened)

Maybe a buddy who knows what you are taking (but doesn't tell it to you) and provides a sanity check?

All of my "buddies" kind of abandoned me pre-pandemic. Much of what was driving me here was boredom, curiosity and solitude.

The CEO/Founder at my old job used to kind of check-in on me from time to time via slack, she thought my work was cool which kind of helped me keep going once I was no longer at the company.