The influence of Hericium erinaceus extract on myelination process in vitro https://pubmed.ncbi.nlm.nih.gov/12675022/
Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacines https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987239/
Protip: If/When buying supplements -- There's many that are just selling capsules of ground myceliated brf (brown rice flour - the substrate inoculated/grown on). Mycelium is the 'roots/pre fruiting stage' of the fungi -- The fruit body/ mushroom itself has much greater concentrations of the desired compounds.
Here's also an easy summary of it's effect and recommendation If one consider buying supplements:
https://www.reddit.com/r/MushroomSupplements/comments/h090ry...
Bought some myself and tried to track its effect by playing 3DS Devilish Brain Training game and track performance.
I feel like I have less "brain-fog" or rather, brain-fog induced procrastination though. But taking this coincided with a less-stressful time of my life so It might be related to both.
I was pretty bummed, I was hoping for a little boost from this as I had read good things about it, including the NIH articles you posted.
I can also confirm, finding the supplements that are not just mostly the ground brown rice flour is also a little difficult.
I'd made sure t get one that was comprised only of the fruiting bodies, with a tested percentage of polysaccharides.
Here's just another link of some lighter details. https://learn.freshcap.com/tips/myceliated-grain/
I learned today that senolytics are molecules that "... can selectively induce death of senescent cells ..."[1]
Which is interesting but you can already do this with exercise.
Nick Lane wrote a fascinating book[2] about this subject which suggests that your internal mitochondrial population is under selection pressure from your own activity.
If you don't put any pressure on it, energetically ill-performing cells are allowed to thrive.
[1] https://en.wikipedia.org/wiki/Senolytic
[2] _Power, Sex, Suicide_
Senolytics might help reducing aged cells to get benefit. Not directly contribute to brain health I think.
TL;DR - CBD may offer a pathway to help control the inflammatory threat to the myelin sheath.
Helps substantially with balance, which should give you some more time on your own feet.
1 March – Scientists use lipid nanoparticles to deliver CRISPR genome editing into the livers of mice, resulting in a 57% reduction of cholesterol levels.[160]
Rejuvenation is not science fiction, it just require funding but expecting this from humanity might be considered science fiction and the situation isn't going to improve given than the Flynn effect is reversing..
See also those related thoughts I wrote years ago: https://github.com/LifeIsStrange/An-algorithm-for-curing-age...