Could use of this be detected by the ad networks and get filtered out?

It's usually detected by anti-click-fraud stuff (since it's the same UA, cookies, and IP that's mass whacking ads, it's the easy case). However, the users of the tool occasionally intend to punish the publishers (people who put these ads on their sites) which does happen for some low volume publishers - like your buddy's blog with AdSense and stuff.

Set it further towards the “rarely” setting, and this is less likely.

It _could_...

But the ad networks get paid for those clicks, so while businesses keep buying ads from a known[1] mostly fraudulent industry, they will not.

1: "Uber discovered they’d been defrauded out of 2/3 of their ad spend" -- https://news.ycombinator.com/item?id=25623858

I usually block all known trackers and advertisers, so even if they could track me (which is less likely to happen) they don't get any benefit from that.

This sounds like cutting off the nose to spite the face. Sure, you may be harming the advertisers, but you are directly reinforcing the ecosystem that creates those annoying ads in the first place by telling them you like those ads.

I hate ads too, but let's not pretend like this childish rebellion is actually self-serving. It's like me saying I'm upset with politics so I'll show the world by not voting.

How does clicking an add in bad faith reinforce the ecosystem? How does thinking you like the product benefit the advertiser or market?

Platform: wow people click ads more often than organic results. We should put more ads in there.

they are not going to notice anyway. just look how difficult it was for Uber

That $.5 to $12 goes to big tech. That's only a win in the case of very vile advertisers.