Could you please provide some evidence for how these impact longevity? Especially those from natural sources, e.g. stevia and monk fruit. Not trying to be snarky, just genuinely curious!
Besides that? I can tell you my body is very sensitive and artificial sweeteners (I literally tried all different kinds) make hell break lose in it, much worse than sugar could ever be. So perhaps they aren't such a great replacement after all? This usually applies to everything humans try to lazily swap out in foods. Oh so I am vegan? Keep these meat replicas coming, only they are like 100 times worse for your health than the real thing...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257251/
> Artificial sweeteners are related to non-alcoholic fatty liver disease: Microbiota dysbiosis as a novel potential mechanism
> Non-alcoholic fatty liver disease (NAFLD) is a systemic and wide-spread disease characterized by accumulation of excess fat in the liver of people who drink little or no alcohol. Artificial sweeteners (ASs) or sugar substitutes are food additives that provide a sweet taste, and are also known as low-calorie or non-calorie sweeteners. Recently people consume increasingly more ASs to reduce their calorie intake. Gut microbiome is a complex ecosystem where 1014 microorganisms play several roles in host nutrition, bone mineralization, immune system regulation, xenobiotics metabolism, proliferation of intestinal cells, and protection against pathogens. A disruption in composition of the normal microbiota is known as ‘gut dysbiosis’ which may adversely affect body metabolism. It has recently been suggested that dysbiosis may contribute to the occurrence of NAFLD. The aim of the present study was to investigate the effects of ASs on the risk of NAFLD. The focus of this review is on microbiota changes and dysbiosis. Increasing evidence shows that ASs have a potential role in microbiota alteration and dysbiosis. We speculate that increased consumption of ASs can further raise the prevalence of NAFLD. However, further human studies are needed to determine this relationship definitively.
All of that is already hard to execute consistently in this society and is our most well known age reducing things we can do currently.
Edit: Some more: Do you fast semi regularly? Eat clean fish? Get outdoors in nature? Avoid allergens to stop triggering your immune system? Live in a dry and mold free house that still gets enough air circulation?